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Drug Metabolism & Disposition

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Table of Contents

July 01, 1984; Volume 12,Issue 4
  • You have access
    Exact mathematical equivalence of the venous equilibration ("well-stirred") model, the sinusoidal perfusion ("parallel-tube") model, and a specific two-compartment open model.
    J G Wagner, G J Szpunar and J J Ferry
    Drug Metabolism and Disposition July 1984, 12 (4) 385-388;
  • You have access
    The metabolism and excretion of 14C-styrene oxide-glutathione adducts administered to the winter flounder, Pseudopleuronectes americanus, a marine teleost. Identification of the corresponding S-cysteine derivatives as major urinary metabolites.
    B Yagen, G L Foureman, Z Ben-Zvi, A J Ryan, O Hernandez, R H Cox and J R Bend
    Drug Metabolism and Disposition July 1984, 12 (4) 389-395;
  • You have access
    Metabolism, disposition, and pharmacokinetics of tracazolate in rat and dog.
    M D Melgar, F R Zuleski and J O Malbica
    Drug Metabolism and Disposition July 1984, 12 (4) 396-402;
  • You have access
    Metabolism of 8-hydroxymethylbenz[a]anthracene by rat liver microsomes. Stereochemistry of dihydrodiol metabolites and the effect of enzyme induction.
    S K Yang, M W Chou, F E Evans and P P Fu
    Drug Metabolism and Disposition July 1984, 12 (4) 403-413;
  • You have access
    Biotransformation and elimination of 14C-flecainide acetate in humans.
    R L McQuinn, G J Quarfoth, J D Johnson, E H Banitt, S V Pathre, S F Chang, R E Ober and G J Conard
    Drug Metabolism and Disposition July 1984, 12 (4) 414-420;
  • You have access
    Metabolism of alcohol and ketone by cytochrome P-450 oxygenase: fluoren-9-ol in equilibrium with fluoren-9-one.
    C Chen, R C Lefers, E L Brough and D P Gurka
    Drug Metabolism and Disposition July 1984, 12 (4) 421-426;
  • You have access
    Oxidative and conjugative metabolism of xenobiotics by isolated rat and hamster acinar cells.
    P Wiebkin, B K Schaeffer, D S Longnecker and T J Curphey
    Drug Metabolism and Disposition July 1984, 12 (4) 427-431;
  • You have access
    Formation of nontoxic reactive metabolites of p-bromophenol. Identification of a new glutathione conjugate.
    T J Monks, S S Lau and R J Highet
    Drug Metabolism and Disposition July 1984, 12 (4) 432-437;
  • You have access
    Disposition of 14C-acetohydroxamic acid and 14C-acetamide in the rat.
    L Putcha, D P Griffith and S Feldman
    Drug Metabolism and Disposition July 1984, 12 (4) 438-443;
  • You have access
    Metabolic disposition of isoxicam in man, monkey, dog, and rat.
    P E Borondy and B M Michniewicz
    Drug Metabolism and Disposition July 1984, 12 (4) 444-451;
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    The disposition and metabolism of a hypnotic benzodiazepine, quazepam, in the hamster and mouse.
    J Hilbert, B Pramanik, S Symchowicz and N Zampaglione
    Drug Metabolism and Disposition July 1984, 12 (4) 452-459;
  • You have access
    Selective inactivation of rat lung and liver microsomal NADPH-cytochrome c reductase by acrolein.
    J M Patel, E Ortiz, C Kolmstetter and K C Leibman
    Drug Metabolism and Disposition July 1984, 12 (4) 460-463;
  • You have access
    The metabolism of avermectin-H2B1a and -H2B1b by pig liver microsomes.
    S H Chiu, E Sestokas, R Taub, J L Smith, B Arison and A Y Lu
    Drug Metabolism and Disposition July 1984, 12 (4) 464-469;
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    Human hepatic cytochrome P-450 composition as probed by in vitro microsomal metabolism of warfarin.
    L S Kaminsky, D A Dunbar, P P Wang, P Beaune, D Larrey, F P Guengerich, R G Schnellmann and I G Sipes
    Drug Metabolism and Disposition July 1984, 12 (4) 470-477;
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    Some chemical and biochemical aspects of liver microsomal metabolism of tamoxifen.
    P C Ruenitz, J R Bagley and C W Pape
    Drug Metabolism and Disposition July 1984, 12 (4) 478-483;
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    The formation and toxicity of catechol metabolites of acetaminophen in mice.
    A J Forte, J M Wilson, J T Slattery and S D Nelson
    Drug Metabolism and Disposition July 1984, 12 (4) 484-491;
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    Disposition and pharmacokinetics of a polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate, in the rat.
    M Hashida, A Kato, Y Takakura and H Sezaki
    Drug Metabolism and Disposition July 1984, 12 (4) 492-499;
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    Effect of pregnancy on tissue distribution of salicylate in rats.
    T Yoshikawa, Y Sugiyama, Y Sawada, T Iga and M Hanano
    Drug Metabolism and Disposition July 1984, 12 (4) 500-505;
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    Separation, characterization, and analysis of epirubicin (4'-epidoxorubicin) and its metabolites from human urine.
    G Cassinelli, E Configliacchi, S Penco, G Rivola, F Arcamone, A Pacciarini and L Ferrari
    Drug Metabolism and Disposition July 1984, 12 (4) 506-510;
  • You have access
    Metabolism of aminoglutethimide in humans. Identification of four new urinary metabolites.
    A B Foster, L J Griggs, I Howe, M Jarman, C S Leung, D Manson and M G Rowlands
    Drug Metabolism and Disposition July 1984, 12 (4) 511-516;
  • You have access
    Biochemical studies on phthalic esters. IV. Metabolism of diheptyl phthalate in rats.
    M Sato, T Adachi, A Tanaka and T Yamaha
    Drug Metabolism and Disposition July 1984, 12 (4) 517-522;
  • You have access
    Evidence for the formation of a novel glutathione conjugate in the metabolism of an aromatic amine derivative.
    D H Hutson, C J Logan and P D Regan
    Drug Metabolism and Disposition July 1984, 12 (4) 523-524;
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In this issue

Drug Metabolism and Disposition
Vol. 12, Issue 4
1 Jul 1984
  • Table of Contents
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  • PBPK Modeling for Clopidogrel and Its Active Metabolite
  • Physiology of the Neonatal Gastrointestinal System
  • Pharmacokinetics and Disposition of Biologics
  • Tissue Drug Concentrations: Beyond the Free Drug Hypothesis
  • Metabolism and Disposition of Volanesorsen across Species
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