Abstract

We need to recognize that incorrect representations of stereochemistry are appearing with increasing frequency in Drug Metabolism and Disposition and other scientific literature. Many misrepresentations of beta-D-glucuronides now exist in the Journal. To assume correctness of any given beta-D-glucuronide structure, or to "lift" or "copy" stereochemical formulas without making checks for correctness of configuration, is unsafe. Fundamental rules and conventions are available for stereochemical representations; and, although these guidelines are not intended to cover every possible case, they are sufficient for avoiding errors and ambiguities in the future of the type presented here.