Drug Metabolism and Disposition: 15 (2)

March 01, 1987; Volume 15,Issue 2

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Relationship between sulfotransferase activity and susceptibility to acetaminophen-induced liver necrosis in the hamster.
M G Miller and D J Jollow

Drug Metabolism and Disposition March 1987, 15 (2) 143-150;
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Dose-dependent pharmacokinetics of ibuprofen in the rat.
A Shah and D Jung

Drug Metabolism and Disposition March 1987, 15 (2) 151-154;
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Nonenzymatic bioreduction in rat liver and kidney of nitroxyl spin labels, potential contrast agents in magnetic resonance imaging.
U G Eriksson, R C Brasch and T N Tozer

Drug Metabolism and Disposition March 1987, 15 (2) 155-160;
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In vitro microsomal metabolism of the leukotriene receptor antagonist, 5-(2-dodecylphenyl)-4,6-dithianonanedioic acid (SK&F 102,081).
J F Newton, K M Straub, R H Dewey, C D Perchonock, T B Leonard, M E McCarthy, J G Gleason and R D Eckardt

Drug Metabolism and Disposition March 1987, 15 (2) 161-167;
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In vivo metabolism of the leukotriene receptor antagonist, 5-(2-dodecylphenyl)-4,6-dithianonanedioic acid (SK&F 102,081) in the guinea pig.
J F Newton, K M Straub, G Y Kuo, C D Perchonock, M E McCarthy, J G Gleason and R K Lynn

Drug Metabolism and Disposition March 1987, 15 (2) 168-176;
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Alterations in biliary excretory function by streptozotocin-induced diabetes.
J B Watkins and T P Dykstra

Drug Metabolism and Disposition March 1987, 15 (2) 177-183;
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Uptake, metabolism, and secretion of 3'-methyl-N,N-dimethyl-4-aminoazobenzene by isolated perfused rat liver.
A R Samuels, L Theilmann, Y R Stollman, A W Wolkoff and M M Bhargava

Drug Metabolism and Disposition March 1987, 15 (2) 184-188;
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Uptake and disposition of putrescine, spermidine, and spermine by rabbit lungs.
S B Rao and H M Mehendale

Drug Metabolism and Disposition March 1987, 15 (2) 189-194;
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Conversion of melphalan to 4-(glutathionyl)phenylalanine. A novel mechanism for conjugation by glutathione-S-transferases.
D M Dulik and C Fenselau

Drug Metabolism and Disposition March 1987, 15 (2) 195-199;
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Conversion of N,N-dimethylaniline to N,N-dimethylaniline-N-oxide by a cytosolic flavin-containing enzyme from Trypanosoma cruzi.
M Agosin and G T Ankley

Drug Metabolism and Disposition March 1987, 15 (2) 200-203;
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Pharmacokinetic interaction between theophylline and chloramphenicol in rats.
M Busby and L J Lesko

Drug Metabolism and Disposition March 1987, 15 (2) 204-206;
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The pharmacokinetics of all-trans-retinoic acid and N-(2-hydroxyethyl)retinamide in mice as determined with a sensitive and convenient procedure. Solid-phase extraction and reverse-phase high performance liquid chromatography.
D M McPhillips, J R Kalin and D L Hill

Drug Metabolism and Disposition March 1987, 15 (2) 207-211;
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Urinary excretion kinetics of famotidine in rats.
J H Lin, L E Los, E H Ulm and D E Duggan

Drug Metabolism and Disposition March 1987, 15 (2) 212-216;
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In vivo and in vitro biotransformation of theobromine by phenobarbital- and 3-methylcholanthrene-inducible cytochrome P-450 monooxygenases in rat liver. Role of thiol compounds.
C A Shively and E S Vesell

Drug Metabolism and Disposition March 1987, 15 (2) 217-224;
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Effects of aging on the properties of rhesus monkey liver microsomal NADPH-cytochrome c (P-450) reductase.
D L Schmucker and R K Wang

Drug Metabolism and Disposition March 1987, 15 (2) 225-232;
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Extraction of omega- and omega-1-hydroxylauric acids with ethyl acetate results in formation of acetoxy products.
A S Salhab, J Applewhite, M W Couch, R T Okita and K T Shiverick

Drug Metabolism and Disposition March 1987, 15 (2) 233-236;
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Biotransformation of caffeine, paraxanthine, theophylline, and theobromine by polycyclic aromatic hydrocarbon-inducible cytochrome(s) P-450 in human liver microsomes.
M E Campbell, D M Grant, T Inaba and W Kalow

Drug Metabolism and Disposition March 1987, 15 (2) 237-249;
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Pharmacokinetics of tetrabenazine and its major metabolite in man and rat. Bioavailability and dose dependency studies.
R Mehvar, F Jamali, M W Watson and D Skelton

Drug Metabolism and Disposition March 1987, 15 (2) 250-255;
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Flavin-containing monooxygenase activity in human liver microsomes.
M E McManus, I Stupans, W Burgess, J A Koenig, P M Hall and D J Birkett

Drug Metabolism and Disposition March 1987, 15 (2) 256-261;
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Metabolism of ethyl 2-(4-chlorophenyl)-5-(2-furyl)-oxazole-4-acetate, a new hypolipidemic agent, in the rat, rabbit, and dog. Glucuronidation of carboxyl group and cleavage of furan ring.
T Kobayashi, H Ando, J Sugihara and S Harigaya

Drug Metabolism and Disposition March 1987, 15 (2) 262-266;
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Mitotane (1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane) metabolism in perfusion studies with dog adrenal glands.
J E Sinsheimer and C J Freeman

Drug Metabolism and Disposition March 1987, 15 (2) 267-269;
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Comparison of hepatic and renal metabolism of acetaminophen in male and female miniature swine.
J O Peggins, T F McMahon, W P Beierschmitt and M Weiner

Drug Metabolism and Disposition March 1987, 15 (2) 270-273;
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In vivo inhibition of phenacetin oxidation by suicide substrate 1-aminobenzotriazole.
B A Mico, D A Federowicz, E Burak and J E Swagzdis

Drug Metabolism and Disposition March 1987, 15 (2) 274-276;
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Pharmacogenetic association between the formation of 4-hydroxymephenytoin and a new metabolite of S-mephenytoin in man.
P J Wedlund, B J Sweetman, G R Wilkinson and R A Branch

Drug Metabolism and Disposition March 1987, 15 (2) 277-279;

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