Drug Metabolism and Disposition: 15 (5)

September 01, 1987; Volume 15,Issue 5

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Criteria for the acceptability of experimental evidence for the enantiomeric composition of xenobiotics and their metabolites.
J Caldwell and B Testa

Drug Metabolism and Disposition September 1987, 15 (5) 587-588;
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The metabolism of the abortifacient terpene, (R)-(+)-pulegone, to a proximate toxin, menthofuran.
W P Gordon, A C Huitric, C L Seth, R H McClanahan and S D Nelson

Drug Metabolism and Disposition September 1987, 15 (5) 589-594;
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The disposition and metabolism of 2',3'-dideoxycytidine, an in vitro inhibitor of human T-lymphotrophic virus type III infectivity, in mice and monkeys.
J A Kelley, C L Litterst, J S Roth, D T Vistica, D G Poplack, D A Cooney, M Nadkarni, F M Balis, S Broder and D G Johns

Drug Metabolism and Disposition September 1987, 15 (5) 595-601;
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Influence of a purified diet and route of administration on the metabolism and disposition of estradiol in B6C3F1 mice.
F R Fullerton, D L Greenman and J F Young

Drug Metabolism and Disposition September 1987, 15 (5) 602-607;
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Distribution of trans-4-hydroxy-2-hexenal and tandem mass spectrometric detection of its urinary mercapturic acid in the rat.
C K Winter, H J Segall and A D Jones

Drug Metabolism and Disposition September 1987, 15 (5) 608-612;
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The role of the liver in mediating the acute toxicity of the pesticide methyl parathion in the mouse.
L G Sultatos

Drug Metabolism and Disposition September 1987, 15 (5) 613-617;
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Ketorolac tromethamine absorption, distribution, metabolism, excretion, and pharmacokinetics in animals and humans.
E J Mroszczak, F W Lee, D Combs, F H Sarnquist, B L Huang, A T Wu, L G Tokes, M L Maddox and D K Cho

Drug Metabolism and Disposition September 1987, 15 (5) 618-626;
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Pharmacokinetics and pharmacodynamics of physostigmine in the rat after intravenous administration.
S M Somani and A Khalique

Drug Metabolism and Disposition September 1987, 15 (5) 627-633;
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Oxidation of the alcohol dehydrogenase inhibitor pyrazole to 4-hydroxypyrazole by microsomes. Effect of cytochrome P-450 inducing agents.
D E Feierman and A I Cederbaum

Drug Metabolism and Disposition September 1987, 15 (5) 634-639;
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Disposition of the monoclonal antibody-vinca alkaloid conjugate, KS1/4-DAVLB (LY256787), in Fischer 344 rats and rhesus monkeys.
M E Spearman, R M Goodwin and D Kau

Drug Metabolism and Disposition September 1987, 15 (5) 640-647;
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Mechanism-based inhibition of cytochrome P-450 by heterocyclic analogues of phencyclidine.
J F Brady, J Dokko, E W Di Stefano and A K Cho

Drug Metabolism and Disposition September 1987, 15 (5) 648-652;
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Relationship between the murine Ah phenotype and the hepatic uptake and metabolism of 2,3,7,8-tetrachlorodibenzo-p-dioxin.
E S Shen and J R Olson

Drug Metabolism and Disposition September 1987, 15 (5) 653-660;
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The in vitro activity, radioimmunoassay cross-reactivity, and molecular weight of thirteen rabbit cyclosporine metabolites.
N R Hartman and I Jardine

Drug Metabolism and Disposition September 1987, 15 (5) 661-664;
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In vivo and in vitro renal metabolism and excretion of benzoic acid by a marine teleost, the southern flounder.
M O James and J B Pritchard

Drug Metabolism and Disposition September 1987, 15 (5) 665-670;
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The disposition of N-(4,6-dimethyl-2-pyrimidinyl)benzene[U-14C]sulfonamide in the rat.
G D Paulson and V J Feil

Drug Metabolism and Disposition September 1987, 15 (5) 671-675;
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The development of hepatic drug-metabolizing enzyme activity in the neonatal calf and its effect on drug disposition.
S E Shoaf, W S Schwark, C L Guard and J G Babish

Drug Metabolism and Disposition September 1987, 15 (5) 676-681;
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The metabolism of 7-ethylbenz[a]anthracene by rat liver microsomal preparations.
S McKay, P B Farmer, P D Cary and P L Grover

Drug Metabolism and Disposition September 1987, 15 (5) 682-694;
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Physiologically based pharmacokinetic model for the renal clearance of salicyluric acid and the interaction with phenolsulfonphthalein in the dog.
F G Russel, A C Wouterse and C A van Ginneken

Drug Metabolism and Disposition September 1987, 15 (5) 695-701;
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Bioactivation of tetrachloroethylene. Role of glutathione S-transferase-catalyzed conjugation versus cytochrome P-450-dependent phospholipid alkylation.
W Dekant, G Martens, S Vamvakas, M Metzler and D Henschler

Drug Metabolism and Disposition September 1987, 15 (5) 702-709;
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Glucuronidation in vitro and in vivo. Comparison of intestinal and hepatic conjugation of morphine, naloxone, and buprenorphine.
M Mistry and J B Houston

Drug Metabolism and Disposition September 1987, 15 (5) 710-717;
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Direct detection of new flucytosine metabolites in human biofluids by 19F nuclear magnetic resonance.
J P Vialaneix, M C Malet-Martino, J S Hoffmann, J Pris and R Martino

Drug Metabolism and Disposition September 1987, 15 (5) 718-724;
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Influence of gonadal hormones upon rat hepatic acetaminophen sulfotransferases.
R F Kane and L J Chen

Drug Metabolism and Disposition September 1987, 15 (5) 725-728;
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Pharmacokinetics of acetaminophen, vancomycin, and antipyrine in the Hanford miniature swine.
M B Bailie, D A Federowicz, K Dolce, C Kahn, B A Mico and M S Landi

Drug Metabolism and Disposition September 1987, 15 (5) 729-730;
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Effect of cyclosporine on hepatic oxidative and conjugative metabolism in rats.
R E Galinsky, D P Alexander and M R Franklin

Drug Metabolism and Disposition September 1987, 15 (5) 731-733;

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