Drug Metabolism and Disposition: 15 (6)

November 01, 1987; Volume 15,Issue 6

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The disposition and pharmacokinetics of ketoconazole in the rat.
R P Remmel, K Amoh and M M Abdel-Monem

Drug Metabolism and Disposition November 1987, 15 (6) 735-739;
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Metabolism and disposition of cyproheptadine and desmethylcyproheptadine in pregnant and fetal rats.
S A Chow and L J Fischer

Drug Metabolism and Disposition November 1987, 15 (6) 740-748;
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Effects of model traumatic injury on hepatic drug metabolism in the rat. VI. Major detoxification/toxification pathways.
L K Griffeth, G M Rosen and E J Rauchman

Drug Metabolism and Disposition November 1987, 15 (6) 749-759;
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Metabolite profile in milk of lactating rats after treatment with a carcinogen, N-2-fluorenylacetamide.
D Malejka-Giganti, W J Magat, A M Adelmann and R W Decker

Drug Metabolism and Disposition November 1987, 15 (6) 760-766;
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Species-dependent enantioselective glucuronidation of three 2-arylpropionic acids. Naproxen, ibuprofen, and benoxaprofen.
M el Mouelhi, H W Ruelius, C Fenselau and D M Dulik

Drug Metabolism and Disposition November 1987, 15 (6) 767-772;
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Pharmacokinetics and metabolism of the antitumor drug amonafide (NSC-308847) in humans.
T B Felder, M A McLean, M L Vestal, K Lu, D Farquhar, S S Legha, R Shah and R A Newman

Drug Metabolism and Disposition November 1987, 15 (6) 773-778;
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Disposition, pharmacokinetics, and metabolism of a dermal dose of [14C]2,5-hexanedione in hens.
E Suwita, A A Nomeir and M B Abou-Donia

Drug Metabolism and Disposition November 1987, 15 (6) 779-785;
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Monooxygenase-mediated activation of chlorotrianisene (TACE) in covalent binding to rat hepatic microsomal proteins.
M J Juedes, W H Bulger and D Kupfer

Drug Metabolism and Disposition November 1987, 15 (6) 786-793;
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The pharmacokinetics of pentane, a by-product of lipid peroxidation.
S R Allerheiligen, T M Ludden and R F Burk

Drug Metabolism and Disposition November 1987, 15 (6) 794-800;
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Co-oxidation of 2-bromohydroquinone by renal prostaglandin synthase. Modulation of prostaglandin synthesis by 2-bromohydroquinone and glutathione.
S S Lau and T J Monks

Drug Metabolism and Disposition November 1987, 15 (6) 801-807;
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N-oxidation of N-methylpyrrolidine released in vivo from cefepime.
S T Forgue, P Kari and R Barbhaiya

Drug Metabolism and Disposition November 1987, 15 (6) 808-815;
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Isolation and characterization of 4'-hydroxy T-2 toxin, a new metabolite of the trichothecene mycotoxin T-2.
C A Knupp, D G Corley, M S Tempesta and S P Swanson

Drug Metabolism and Disposition November 1987, 15 (6) 816-820;
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Metabolism and excretion of dinitrobenzenes by male Fischer-344 rats.
D D Nystrom and D E Rickert

Drug Metabolism and Disposition November 1987, 15 (6) 821-825;
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Cryopreservation of rat and dog hepatocytes for studies of xenobiotic metabolism and activation.
G Powis, K S Santone, D C Melder, L Thomas, D J Moore and T J Wilke

Drug Metabolism and Disposition November 1987, 15 (6) 826-832;
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Oxidative metabolism of butylated hydroxytoluene by hepatic and pulmonary microsomes from rats and mice.
J A Thompson, A M Malkinson, M D Wand, S L Mastovich, E W Mead, K M Schullek and W G Laudenschlager

Drug Metabolism and Disposition November 1987, 15 (6) 833-840;
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Evidence for diazotization of 14C-sulfamethazine [4-amino-N-(4,6-dimethyl-2-pyrimidinyl)benzene[U-14C]sulfonamide] in swine. The effect of nitrite.
G D Paulson and V J Feil

Drug Metabolism and Disposition November 1987, 15 (6) 841-845;
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Mechanism-based inactivation of the major beta-naphthoflavone-inducible isozyme of rat liver cytochrome P-450 by the chloramphenicol analog N-(2-p-nitrophenethyl)dichloroacetamide.
N E Miller and J R Halpert

Drug Metabolism and Disposition November 1987, 15 (6) 846-851;
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Selective inactivation by chloramphenicol of the major phenobarbital-inducible isozyme of dog liver cytochrome P-450.
P J Ciaccio, D B Duignan and J R Halpert

Drug Metabolism and Disposition November 1987, 15 (6) 852-856;
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Conversion of bromobenzene to 3-bromophenol. A route to 3- and 4-bromophenol through sulfur-series intermediates derived from the 3,4-oxide.
K Lertratanangkoon, E C Horning and M G Horning

Drug Metabolism and Disposition November 1987, 15 (6) 857-867;
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Isolation and identification of major metabolites of tixocortol pivalate in human urine.
F Chanoine, C Grenot, N Sellier, W E Barrett, R M Thompson, A F Fentiman, J R Nixon, R Goyer and J L Junien

Drug Metabolism and Disposition November 1987, 15 (6) 868-876;
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Mechanism of metabolic cleavage of a furan ring.
T Kobayashi, J Sugihara and S Harigaya

Drug Metabolism and Disposition November 1987, 15 (6) 877-881;
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Phenolic metabolites of amitriptyline and nortriptyline in rat bile.
U Breyer-Pfaff, A Prox, H Wachsmuth and P P Yao

Drug Metabolism and Disposition November 1987, 15 (6) 882-889;
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Amitriptyline metabolites in human urine. Identification of phenols, dihydrodiols, glycols, and ketones.
A Prox and U Breyer-Pfaff

Drug Metabolism and Disposition November 1987, 15 (6) 890-896;
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19F nuclear magnetic resonance analysis of the carbamate reaction of alpha-fluoro-beta-alanine (FBAL), the major catabolite of fluoropyrimidines. Application to FBAL carbamate determination in body fluids of patients treated with 5'-deoxy-5-fluorouridine.
R Martino, M C Malet-Martino, C Vialaneix, A Lopez and M Bon

Drug Metabolism and Disposition November 1987, 15 (6) 897-904;
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Excretion and biotransformation of alfentanil and sufentanil in rats and dogs.
W Meuldermans, J Hendrickx, W Lauwers, R Hurkmans, E Swysen, J Thijssen, P Timmerman, R Woestenborghs and J Heykants

Drug Metabolism and Disposition November 1987, 15 (6) 905-913;
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Metabolism of (+)-trans-delta 8-tetrahydrocannabinol in the mouse in vitro and in vivo.
D J Harvey and H J Marriage

Drug Metabolism and Disposition November 1987, 15 (6) 914-920;
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Identification of the etodolac metabolite, 4-ureidoetodolac, in mouse, rat, dog, and man.
E S Ferdinandi, D Cochran and R Gedamke

Drug Metabolism and Disposition November 1987, 15 (6) 921-924;
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[3H]chloramphenicol metabolism in human volunteer: oxamic acid as a new major metabolite.
D E Corpet and G F Bories

Drug Metabolism and Disposition November 1987, 15 (6) 925-927;

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