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Drug Metabolism & Disposition

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Table of Contents

November 01, 1987; Volume 15,Issue 6
  • You have access
    The disposition and pharmacokinetics of ketoconazole in the rat.
    R P Remmel, K Amoh and M M Abdel-Monem
    Drug Metabolism and Disposition November 1987, 15 (6) 735-739;
  • You have access
    Metabolism and disposition of cyproheptadine and desmethylcyproheptadine in pregnant and fetal rats.
    S A Chow and L J Fischer
    Drug Metabolism and Disposition November 1987, 15 (6) 740-748;
  • You have access
    Effects of model traumatic injury on hepatic drug metabolism in the rat. VI. Major detoxification/toxification pathways.
    L K Griffeth, G M Rosen and E J Rauchman
    Drug Metabolism and Disposition November 1987, 15 (6) 749-759;
  • You have access
    Metabolite profile in milk of lactating rats after treatment with a carcinogen, N-2-fluorenylacetamide.
    D Malejka-Giganti, W J Magat, A M Adelmann and R W Decker
    Drug Metabolism and Disposition November 1987, 15 (6) 760-766;
  • You have access
    Species-dependent enantioselective glucuronidation of three 2-arylpropionic acids. Naproxen, ibuprofen, and benoxaprofen.
    M el Mouelhi, H W Ruelius, C Fenselau and D M Dulik
    Drug Metabolism and Disposition November 1987, 15 (6) 767-772;
  • You have access
    Pharmacokinetics and metabolism of the antitumor drug amonafide (NSC-308847) in humans.
    T B Felder, M A McLean, M L Vestal, K Lu, D Farquhar, S S Legha, R Shah and R A Newman
    Drug Metabolism and Disposition November 1987, 15 (6) 773-778;
  • You have access
    Disposition, pharmacokinetics, and metabolism of a dermal dose of [14C]2,5-hexanedione in hens.
    E Suwita, A A Nomeir and M B Abou-Donia
    Drug Metabolism and Disposition November 1987, 15 (6) 779-785;
  • You have access
    Monooxygenase-mediated activation of chlorotrianisene (TACE) in covalent binding to rat hepatic microsomal proteins.
    M J Juedes, W H Bulger and D Kupfer
    Drug Metabolism and Disposition November 1987, 15 (6) 786-793;
  • You have access
    The pharmacokinetics of pentane, a by-product of lipid peroxidation.
    S R Allerheiligen, T M Ludden and R F Burk
    Drug Metabolism and Disposition November 1987, 15 (6) 794-800;
  • You have access
    Co-oxidation of 2-bromohydroquinone by renal prostaglandin synthase. Modulation of prostaglandin synthesis by 2-bromohydroquinone and glutathione.
    S S Lau and T J Monks
    Drug Metabolism and Disposition November 1987, 15 (6) 801-807;
  • You have access
    N-oxidation of N-methylpyrrolidine released in vivo from cefepime.
    S T Forgue, P Kari and R Barbhaiya
    Drug Metabolism and Disposition November 1987, 15 (6) 808-815;
  • You have access
    Isolation and characterization of 4'-hydroxy T-2 toxin, a new metabolite of the trichothecene mycotoxin T-2.
    C A Knupp, D G Corley, M S Tempesta and S P Swanson
    Drug Metabolism and Disposition November 1987, 15 (6) 816-820;
  • You have access
    Metabolism and excretion of dinitrobenzenes by male Fischer-344 rats.
    D D Nystrom and D E Rickert
    Drug Metabolism and Disposition November 1987, 15 (6) 821-825;
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    Cryopreservation of rat and dog hepatocytes for studies of xenobiotic metabolism and activation.
    G Powis, K S Santone, D C Melder, L Thomas, D J Moore and T J Wilke
    Drug Metabolism and Disposition November 1987, 15 (6) 826-832;
  • You have access
    Oxidative metabolism of butylated hydroxytoluene by hepatic and pulmonary microsomes from rats and mice.
    J A Thompson, A M Malkinson, M D Wand, S L Mastovich, E W Mead, K M Schullek and W G Laudenschlager
    Drug Metabolism and Disposition November 1987, 15 (6) 833-840;
  • You have access
    Evidence for diazotization of 14C-sulfamethazine [4-amino-N-(4,6-dimethyl-2-pyrimidinyl)benzene[U-14C]sulfonamide] in swine. The effect of nitrite.
    G D Paulson and V J Feil
    Drug Metabolism and Disposition November 1987, 15 (6) 841-845;
  • You have access
    Mechanism-based inactivation of the major beta-naphthoflavone-inducible isozyme of rat liver cytochrome P-450 by the chloramphenicol analog N-(2-p-nitrophenethyl)dichloroacetamide.
    N E Miller and J R Halpert
    Drug Metabolism and Disposition November 1987, 15 (6) 846-851;
  • You have access
    Selective inactivation by chloramphenicol of the major phenobarbital-inducible isozyme of dog liver cytochrome P-450.
    P J Ciaccio, D B Duignan and J R Halpert
    Drug Metabolism and Disposition November 1987, 15 (6) 852-856;
  • You have access
    Conversion of bromobenzene to 3-bromophenol. A route to 3- and 4-bromophenol through sulfur-series intermediates derived from the 3,4-oxide.
    K Lertratanangkoon, E C Horning and M G Horning
    Drug Metabolism and Disposition November 1987, 15 (6) 857-867;
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    Isolation and identification of major metabolites of tixocortol pivalate in human urine.
    F Chanoine, C Grenot, N Sellier, W E Barrett, R M Thompson, A F Fentiman, J R Nixon, R Goyer and J L Junien
    Drug Metabolism and Disposition November 1987, 15 (6) 868-876;
  • You have access
    Mechanism of metabolic cleavage of a furan ring.
    T Kobayashi, J Sugihara and S Harigaya
    Drug Metabolism and Disposition November 1987, 15 (6) 877-881;
  • You have access
    Phenolic metabolites of amitriptyline and nortriptyline in rat bile.
    U Breyer-Pfaff, A Prox, H Wachsmuth and P P Yao
    Drug Metabolism and Disposition November 1987, 15 (6) 882-889;
  • You have access
    Amitriptyline metabolites in human urine. Identification of phenols, dihydrodiols, glycols, and ketones.
    A Prox and U Breyer-Pfaff
    Drug Metabolism and Disposition November 1987, 15 (6) 890-896;
  • You have access
    19F nuclear magnetic resonance analysis of the carbamate reaction of alpha-fluoro-beta-alanine (FBAL), the major catabolite of fluoropyrimidines. Application to FBAL carbamate determination in body fluids of patients treated with 5'-deoxy-5-fluorouridine.
    R Martino, M C Malet-Martino, C Vialaneix, A Lopez and M Bon
    Drug Metabolism and Disposition November 1987, 15 (6) 897-904;
  • You have access
    Excretion and biotransformation of alfentanil and sufentanil in rats and dogs.
    W Meuldermans, J Hendrickx, W Lauwers, R Hurkmans, E Swysen, J Thijssen, P Timmerman, R Woestenborghs and J Heykants
    Drug Metabolism and Disposition November 1987, 15 (6) 905-913;
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    Metabolism of (+)-trans-delta 8-tetrahydrocannabinol in the mouse in vitro and in vivo.
    D J Harvey and H J Marriage
    Drug Metabolism and Disposition November 1987, 15 (6) 914-920;
  • You have access
    Identification of the etodolac metabolite, 4-ureidoetodolac, in mouse, rat, dog, and man.
    E S Ferdinandi, D Cochran and R Gedamke
    Drug Metabolism and Disposition November 1987, 15 (6) 921-924;
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    [3H]chloramphenicol metabolism in human volunteer: oxamic acid as a new major metabolite.
    D E Corpet and G F Bories
    Drug Metabolism and Disposition November 1987, 15 (6) 925-927;
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In this issue

Drug Metabolism and Disposition
Vol. 15, Issue 6
1 Nov 1987
  • Table of Contents
  • Index by author
  • Back Matter (PDF)
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  • Cannabinoid Metabolites as CYP450 Inhibitors
  • Physiology of the Neonatal Gastrointestinal System
  • Pharmacokinetics and Disposition of Biologics
  • Alternative P450 Splicing Redirects Human Drug Metabolism
  • Switch from CAR to PXR in the Presence of EGF
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