Drug Metabolism and Disposition: 16 (1)

January 01, 1988; Volume 16,Issue 1

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The 1986 Bernard B. Brodie award lecture. The genetic regulation of drug-metabolizing enzymes.
D W Nebert

Drug Metabolism and Disposition January 1988, 16 (1) 1-8;
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l-alpha-Acetylmethadol administration to lactating rat dams. Effect on hepatic aniline hydroxylase and ethylmorphine N-demethylase activities in rat pups.
G A Lesher and W P Beierschmitt

Drug Metabolism and Disposition January 1988, 16 (1) 9-14;
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In vitro evidence against the oxidation of quinidine by the sparteine/debrisoquine monooxygenase of human liver.
S V Otton, R U Brinn and L F Gram

Drug Metabolism and Disposition January 1988, 16 (1) 15-17;
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Interspecies comparison of acivicin pharmacokinetics.
J P McGovren, M G Williams and J C Stewart

Drug Metabolism and Disposition January 1988, 16 (1) 18-22;
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The effects of tin-protoporphyrin administration on hepatic xenobiotic metabolizing enzymes in the juvenile rat.
D L Stout and F F Becker

Drug Metabolism and Disposition January 1988, 16 (1) 23-26;
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Polyethylene glycol-L-asparaginase and L-asparaginase studies in rabbits.
D H Ho, C Y Wang, J R Lin, N Brown, R A Newman and I H Krakoff

Drug Metabolism and Disposition January 1988, 16 (1) 27-29;
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UDP-glucuronosyltransferase activity toward digitoxigenin-monodigitoxoside. Differences in activation and induction properties in rat and mouse liver.
G A Hazelton and C D Klaassen

Drug Metabolism and Disposition January 1988, 16 (1) 30-36;
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Inhibition of rat liver aldehyde dehydrogenases by acrolein.
D Y Mitchell and D R Petersen

Drug Metabolism and Disposition January 1988, 16 (1) 37-42;
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Effect of monooxygenase inducers and inhibitors on the hepatic metabolism of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat and hamster.
V J Wroblewski and J R Olson

Drug Metabolism and Disposition January 1988, 16 (1) 43-51;
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Kinetic studies on the competition between famotidine and cimetidine in rats. Evidence of multiple renal secretory systems for organic cations.
J H Lin, L E Los, E H Ulm and D E Duggan

Drug Metabolism and Disposition January 1988, 16 (1) 52-56;
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Cyclosporine-cimetidine interaction.
M J D'Souza, S H Pollock and H M Solomon

Drug Metabolism and Disposition January 1988, 16 (1) 57-59;
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Metabolism of 2,3-dichloro-1-propene in the rat. Consideration of bioactivation mechanisms.
E Eder and K Dornbusch

Drug Metabolism and Disposition January 1988, 16 (1) 60-68;
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Metabolism of bepridil in laboratory animals and humans.
W N Wu, J F Hills, S Y Chang and K T Ng

Drug Metabolism and Disposition January 1988, 16 (1) 69-77;
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19F NMR spectrometry evidence for bile acid conjugates of alpha-fluoro-beta-alanine as the main biliary metabolites of antineoplastic fluoropyrimidines in humans.
M C Malet-Martino, J Bernadou, R Martino and J P Armand

Drug Metabolism and Disposition January 1988, 16 (1) 78-84;
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Biliary excretion of a glutathione conjugate of busulfan and 1,4-diiodobutane in the rat.
D H Marchand, R P Remmel and M M Abdel-Monem

Drug Metabolism and Disposition January 1988, 16 (1) 85-92;
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Neonatal programming of ethylmorphine demethylase and corticosteroid 5 alpha-reductase by testosterone, dihydrotestosterone, and estradiol. Effects of an anti-estrogen, an anti-androgen, and an inhibitor of estrogen synthetase.
E F Reyes and B B Virgo

Drug Metabolism and Disposition January 1988, 16 (1) 93-97;
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Interaction of epicatechins derived from green tea with rat hepatic cytochrome P-450.
Z Y Wang, M Das, D R Bickers and H Mukhtar

Drug Metabolism and Disposition January 1988, 16 (1) 98-103;
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In vivo 31P nuclear magnetic resonance studies on the absorption of triphenyl phosphite and tri-o-cresyl phosphate following subcutaneous administration in hens.
C D Carrington, C T Burt and M B Abou-Donia

Drug Metabolism and Disposition January 1988, 16 (1) 104-109;
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Induction of sulfamethazine acetylation by hydrocortisone in the rabbit.
P T Reeves, R F Minchin and K F Ilett

Drug Metabolism and Disposition January 1988, 16 (1) 110-115;
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Regional distribution of xenobiotic metabolizing enzymes in respiratory airways of dogs.
J A Bond, J R Harkema and V I Russell

Drug Metabolism and Disposition January 1988, 16 (1) 116-124;
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Pharmacokinetics of nicotine and 12 metabolites in the rat. Application of a new radiometric high performance liquid chromatography assay.
G A Kyerematen, L H Taylor, J D deBethizy and E S Vesell

Drug Metabolism and Disposition January 1988, 16 (1) 125-129;
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Disposition of cefixime in the pregnant and lactating rat. Transfer to the fetus and nursing pup.
E Halperin-Walega, V K Batra, A P Tonelli, A Barr and A Yacobi

Drug Metabolism and Disposition January 1988, 16 (1) 130-134;
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Potential metabolic basis for enflurane hepatitis and the apparent cross-sensitization between enflurane and halothane.
D D Christ, H Satoh, J G Kenna and L R Pohl

Drug Metabolism and Disposition January 1988, 16 (1) 135-140;
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Pharmacokinetics and toxicity of high doses of antibody Fab fragments in rats.
P R Pentel, D E Keyler, D G Gilbertson, G Ruth and S M Pond

Drug Metabolism and Disposition January 1988, 16 (1) 141-145;
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Metabolic inhibition and di-2-ethylhexyl phthalate pharmacokinetics in fish.
A H Karara and W L Hayton

Drug Metabolism and Disposition January 1988, 16 (1) 146-150;
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Characterization of mixed-function oxidases and purified cytochrome P-450 of livers of house musk shrew, Suncus murinus.
K Mizokami, M Fukuhara, T Nohmi, M Sunouchi, K Fujimori, A Takanaka and Y Omori

Drug Metabolism and Disposition January 1988, 16 (1) 151-155;
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Enzymatic oxidation of 7-hydroxylated delta 8-tetrahydrocannabinol to 7-oxo-delta 8-tetrahydrocannabinol by hepatic microsomes of the guinea pig.
S Narimatsu, K Matsubara, T Shimonishi, K Watanabe, I Yamamoto and H Yoshimura

Drug Metabolism and Disposition January 1988, 16 (1) 156-161;
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The effect of N-acetylcysteine on the toxicity induced by N-nitrosodimethylamine.
W A Garland, E P Norkus, W A Kuenzig and M L Powell

Drug Metabolism and Disposition January 1988, 16 (1) 162-165;

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