Drug Metabolism and Disposition: 16 (4)

July 01, 1988; Volume 16,Issue 4

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Distribution of [3H]diisopropylfluorophosphate, [3H]soman, [3H]sarin, and their metabolites in mouse brain.
P J Little, J A Scimeca and B R Martin

Drug Metabolism and Disposition July 1988, 16 (4) 515-520;
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The influence of diffusional barriers on presystemic gut elimination.
P R Gwilt, S Comer, P R Chaturvedi and D H Waters

Drug Metabolism and Disposition July 1988, 16 (4) 521-526;
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Effect of galactosamine-induced hepatic UDP-glucuronic acid depletion on acetaminophen elimination in rats. Dispositional differences between hepatically and extrahepatically formed glucuronides of acetaminophen and other chemicals.
Z Gregus, C Madhu, D Goon and C D Klaassen

Drug Metabolism and Disposition July 1988, 16 (4) 527-533;
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The disposition of [3H]diisopropylfluorophosphate in guinea pigs after inhalation.
J A Scimeca and B R Martin

Drug Metabolism and Disposition July 1988, 16 (4) 534-539;
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Enantioselective disposition and protein binding of [(5,6-dichloro-9a-propyl-3-oxo-2,3,9,9a-tetrahydro-1-H-fluoren-7 -yl)-oxy] acetic acid, a new cerebral antiedemic agent, in rats.
J H Lin and J Y Hsieh

Drug Metabolism and Disposition July 1988, 16 (4) 540-545;
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Dose-response behavior of the induction of alpha 1-acid glycoprotein by phenobarbital in the dog.
F P Abramson

Drug Metabolism and Disposition July 1988, 16 (4) 546-550;
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Ascorbic acid deficiency and hepatic UDP-glucuronyltransferase.
C M Neumann and V G Zannoni

Drug Metabolism and Disposition July 1988, 16 (4) 551-556;
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Distribution of microsomal monooxygenases in the rabbit respiratory tract.
P J Sabourin, R E Tynes, R M Philpot, S Winquist and A R Dahl

Drug Metabolism and Disposition July 1988, 16 (4) 557-562;
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Species-dependent binding of disopyramide enantiomers.
J J Lima

Drug Metabolism and Disposition July 1988, 16 (4) 563-567;
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Disposition and metabolism of prinomide in laboratory animals.
H Egger, W Itterly, V John, R Rodebaugh, C Shimanskas, F Stancato and A Kapoor

Drug Metabolism and Disposition July 1988, 16 (4) 568-575;
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Coordinated maternal imprinting and paternal genotype determined the ultimate level of hepatic cytochrome P-450 and associated monooxygenase activities.
V J Simpson, H E Zhau, M N Runner and L W Chung

Drug Metabolism and Disposition July 1988, 16 (4) 576-581;
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Foreign compound metabolism studies with human liver obtained as surgical waste. Relation to donor characteristics and effects of tissue storage.
G Powis, I Jardine, R Van Dyke, R Weinshilboum, D Moore, T Wilke, W Rhodes, R Nelson, L Benson and C Szumlanski

Drug Metabolism and Disposition July 1988, 16 (4) 582-589;
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Cellular and subcellular localization of a binding protein for polychlorinated biphenyls in rat lung.
J Lund, T Devereux, H Glaumann and J A Gustafsson

Drug Metabolism and Disposition July 1988, 16 (4) 590-599;
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Metabolism of N,N-diethyl-m-toluamide (DEET) by liver microsomes from male and female rats. Simultaneous quantitation of DEET and its metabolites by high performance liquid chromatography.
J M Yeung and W G Taylor

Drug Metabolism and Disposition July 1988, 16 (4) 600-604;
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Metabolism of diazepam in vitro by human liver. Independent variability of N-demethylation and C3-hydroxylation.
T Inaba, A Tait, M Nakano, W A Mahon and W Kalow

Drug Metabolism and Disposition July 1988, 16 (4) 605-608;
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Biopharmaceutical characterization of 450191-S, a ring-opened derivative of 1,4-benzodiazepine. II. Evidence for reduced first-pass extraction by rat liver.
M Koike, S Futaguchi, S Takahashi and K Sugeno

Drug Metabolism and Disposition July 1988, 16 (4) 609-615;
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Stereoselective N-oxygenation of zimeldine and homozimeldine by the flavin-containing monooxygenase.
J R Cashman, J Proudfoot, D W Pate and T Högberg

Drug Metabolism and Disposition July 1988, 16 (4) 616-622;
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Stereoselective pharmacokinetics of ketoprofen in the rat. Influence of route of administration.
R T Foster and F Jamali

Drug Metabolism and Disposition July 1988, 16 (4) 623-626;
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Substrate specificity and enantioselectivity of arylcarboxylic acid glucuronidation.
S Fournel-Gigleux, C Hamar-Hansen, N Motassim, B Antoine, O Mothe, D Decolin, J Caldwell and G Siest

Drug Metabolism and Disposition July 1988, 16 (4) 627-634;
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New aspects of metabolic conjugation of chloramphenicol.
J M Wal, J C Peleran, E Perdu, D Rao and G Bories

Drug Metabolism and Disposition July 1988, 16 (4) 635-639;
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Possible hemodynamic basis to urethane anesthesia-induced reductions in renal clearance.
M Gumbleton, P J Nicholls and G Taylor

Drug Metabolism and Disposition July 1988, 16 (4) 640-644;
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Nonlinear tissue distribution of ouabain in rabbits.
H Harashima, Y Sugiyama, T Iga and M Hanano

Drug Metabolism and Disposition July 1988, 16 (4) 645-649;
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Glucuronidation in 4-chlorobiphenyl metabolism by rat and human liver microsomes.
R P Volp

Drug Metabolism and Disposition July 1988, 16 (4) 650-652;
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Effect of enoxacin and 4-oxo-enoxacin on antipyrine disposition in the rat.
D J Edwards, N M Waite and C K Svensson

Drug Metabolism and Disposition July 1988, 16 (4) 653-655;
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Isotope effects on formaldehyde oxidation.
H D Heck and M Casanova

Drug Metabolism and Disposition July 1988, 16 (4) 656-657;

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