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Drug Metabolism & Disposition

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Table of Contents

January 01, 1989; Volume 17,Issue 1
  • You have access
    Effect of tick-borne fever (Ehrlichia phagocytophila) and trypanosomiasis (Trypanosoma brucei 1066) on the pharmacokinetics of sulfadimidine and its metabolites in goats.
    H van Gogh, A D Watson, J F Nouws, J Nieuwenhuijs and A S van Miert
    Drug Metabolism and Disposition January 1989, 17 (1) 1-6;
  • You have access
    Selective mechanism-based inactivation of the major phenobarbital-inducible P-450 cytochrome from rabbit liver by phencyclidine and its oxidation product, the iminium compound.
    Y Osawa and M J Coon
    Drug Metabolism and Disposition January 1989, 17 (1) 7-13;
  • You have access
    Metabolism of atrial natriuretic peptide. Extraction by organs in the rat.
    P A Krieter and A J Trapani
    Drug Metabolism and Disposition January 1989, 17 (1) 14-19;
  • You have access
    Activities of cytosolic and microsomal drug oxidases of rat hepatocytes in primary culture.
    A J Sherratt and L A Damani
    Drug Metabolism and Disposition January 1989, 17 (1) 20-25;
  • You have access
    Selective inactivation of rat liver cytochromes P-450 by 21-chlorinated steroids.
    J Halpert, J Y Jaw, L J Cornfield, C Balfour and E A Mash
    Drug Metabolism and Disposition January 1989, 17 (1) 26-31;
  • You have access
    Effect of organ perfusion on renal drug transport. Application to furosemide in the isolated perfused rat kidney.
    L J Lee and D E Smith
    Drug Metabolism and Disposition January 1989, 17 (1) 32-36;
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    Inhibition of 3-methylindole bioactivation by the cytochrome P-450 suicide substrates 1-aminobenzotriazole and alpha-methylbenzylaminobenzotriazole.
    J C Huijzer, J D Adams, J Y Jaw and G S Yost
    Drug Metabolism and Disposition January 1989, 17 (1) 37-42;
  • You have access
    Isolation and identification of 6-desmethylnaproxen sulfate as a new metabolite of naproxen in human plasma.
    C H Kiang, C Lee and S Kushinsky
    Drug Metabolism and Disposition January 1989, 17 (1) 43-48;
  • You have access
    Fluconazole is a potent inhibitor of antipyrine metabolism in vivo in mice.
    I La Delfa, Q M Zhu, Z Mo and T F Blaschke
    Drug Metabolism and Disposition January 1989, 17 (1) 49-53;
  • You have access
    Cilastatin-insulin interaction in the rat.
    G C Tompkins, L J Brunner and D R Luke
    Drug Metabolism and Disposition January 1989, 17 (1) 54-57;
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    Characterization of a carbamic acid ester glucuronide of the secondary amine sertraline.
    L M Tremaine, J G Stroh and R A Ronfeld
    Drug Metabolism and Disposition January 1989, 17 (1) 58-63;
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    Stereoselective oxidation of nilvadipine, a new dihydropyridine calcium antagonist, in rat and dog liver.
    T Niwa, Y Tokuma, K Nakagawa and H Noguchi
    Drug Metabolism and Disposition January 1989, 17 (1) 64-68;
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    Identification of two main urinary metabolites of [14C]omeprazole in humans.
    L Renberg, R Simonsson and K J Hoffmann
    Drug Metabolism and Disposition January 1989, 17 (1) 69-76;
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    (8S)-(glutathion-S-yl)dihydromorphinone, a novel metabolite of morphine from guinea pig bile.
    T Ishida, Y Kumagai, Y Ikeda, K Ito, M Yano, S Toki, K Mihashi, T Fujioka, Y Iwase and S Hachiyama
    Drug Metabolism and Disposition January 1989, 17 (1) 77-81;
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    Central nervous system kinetics of atenolol and metoprolol in the dog during long term treatment.
    T Abrahamsson, E Lignell, A Mikulski, S G Olovson and C G Regårdh
    Drug Metabolism and Disposition January 1989, 17 (1) 82-86;
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    The pharmacokinetics of salicylate in the pregnant Wistar rat.
    M Dean, S Penglis and B Stock
    Drug Metabolism and Disposition January 1989, 17 (1) 87-90;
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    Temporal variations in the pharmacokinetics of isoniazid and N-acetylisoniazid in rats.
    P M Belanger, M Lalande, F M Dore and G Labrecque
    Drug Metabolism and Disposition January 1989, 17 (1) 91-97;
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    In vivo and in vitro pharmacokinetic differences between four structurally closely related anthracyclines in hematopoietic cell subtypes in humans.
    P A Speth, P C Linssen, E F Termond, J B Boezeman, H M Wessels and C Haanen
    Drug Metabolism and Disposition January 1989, 17 (1) 98-105;
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    Pulmonary toxicity of trichloroethylene in mice. Covalent binding and morphological manifestations.
    P G Forkert and D W Birch
    Drug Metabolism and Disposition January 1989, 17 (1) 106-113;
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    Hepatic drug metabolism in female Fischer rats as a function of age.
    L E Rikans
    Drug Metabolism and Disposition January 1989, 17 (1) 114-116;
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In this issue

Drug Metabolism and Disposition
Vol. 17, Issue 1
1 Jan 1989
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Most Cited
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
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