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Abstract

Selective mechanism-based inactivation of the major phenobarbital-inducible P-450 cytochrome from rabbit liver by phencyclidine and its oxidation product, the iminium compound.

Y Osawa and M J Coon
Drug Metabolism and Disposition January 1989, 17 (1) 7-13;

Article Information

vol. 17 no. 1 7-13
PubMed 
2566474
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Published online January 1, 1989.

Author Information

  1. Y Osawa and
  2. M J Coon
  1. Department of Biological Chemistry, Medical School, University of Michigan, Ann Arbor 48109.

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    Abstract

    Selective mechanism-based inactivation of the major phenobarbital-inducible P-450 cytochrome from rabbit liver by phencyclidine and its oxidation product, the iminium compound.

    Y Osawa and M J Coon
    Drug Metabolism and Disposition January 1, 1989, 17 (1) 7-13;
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