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Drug Metabolism & Disposition

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Table of Contents

January 01, 1990; Volume 18,Issue 1
  • You have access
    Pharmacokinetics and metabolism of the pharmacologically active 4'-hydroxylated metabolite of propranolol in the dog.
    D D Christ, U K Walle, J E Oatis and T Walle
    Drug Metabolism and Disposition January 1990, 18 (1) 1-4;
  • You have access
    Metabolism of chloronitrobenzenes by isolated rat hepatocytes.
    D E Rickert and S D Held
    Drug Metabolism and Disposition January 1990, 18 (1) 5-9;
  • You have access
    Effect of microsomal enzyme inducers on biliary and urinary excretion of acetaminophen metabolites in rats. Decreased hepatobiliary and increased hepatovascular transport of acetaminophen-glucuronide after microsomal enzyme induction.
    Z Gregus, C Madhu and C D Klaassen
    Drug Metabolism and Disposition January 1990, 18 (1) 10-19;
  • You have access
    Comparative studies of the in vitro metabolism and covalent binding of 14C-benzene by liver slices and microsomal fraction of mouse, rat, and human.
    J I Brodfuehrer, D E Chapman, T J Wilke and G Powis
    Drug Metabolism and Disposition January 1990, 18 (1) 20-27;
  • You have access
    Structural characterization of urinary metabolites of the antiarrhythmic drug encainide in human subjects.
    H K Jajoo, R F Mayol, J A LaBudde and I A Blair
    Drug Metabolism and Disposition January 1990, 18 (1) 28-35;
  • You have access
    Azoreduction of dimethylaminoazobenzene (DAB) in primary cultures of rat hepatocytes. Effect of hypolipidemic agents.
    A M Stoddart and W G Levine
    Drug Metabolism and Disposition January 1990, 18 (1) 36-41;
  • You have access
    Pharmacokinetics of disopyramide in the dog. Importance of mono-N-dealkylated metabolite kinetics in assessing pharmacokinetic modeling of the parent drug.
    C S Cook, P R Gwilt, K Kowalski, S Gupta, J Oppermann and A Karim
    Drug Metabolism and Disposition January 1990, 18 (1) 42-49;
  • You have access
    Purification and characterization of human kidney cytosolic cysteine conjugate beta-lyase activity.
    L H Lash, R M Nelson, R A Van Dyke and M W Anders
    Drug Metabolism and Disposition January 1990, 18 (1) 50-54;
  • You have access
    Pharmacokinetics of prednisolone and its local anti-inflammatory steroid-21-oate ester derivatives. In vitro and in vivo comparative study.
    S M al-Habet, I B Taraporewala and H J Lee
    Drug Metabolism and Disposition January 1990, 18 (1) 55-60;
  • You have access
    Thiol-mediated catalysis of nitroglycerin degradation by serum proteins. Increase in metabolism was not accompanied by S-nitrosothiol production.
    S Chong and H L Fung
    Drug Metabolism and Disposition January 1990, 18 (1) 61-67;
  • You have access
    Isolation and identification of a novel human metabolite of cyclosporin A: dihydro-CsA M17.
    G P Meier, S B Park, G C Yee and D J Gmur
    Drug Metabolism and Disposition January 1990, 18 (1) 68-71;
  • You have access
    Phenytoin disposition in the pregnant rat. Dose-dependent studies and salicylate effects.
    P A Cleveland and C T Ueda
    Drug Metabolism and Disposition January 1990, 18 (1) 72-79;
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    A reversible clearance model for the enterohepatic circulation of drug and conjugate metabolite pair.
    R L Semmes and D D Shen
    Drug Metabolism and Disposition January 1990, 18 (1) 80-87;
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    Disposition of ethimizol, a xanthine-related nootropic drug, in perfused rat liver and isolated hepatocytes.
    S Bezek, M Kukan, Z Kállay, T Trnovec, M Stefek and L B Piotrovskiy
    Drug Metabolism and Disposition January 1990, 18 (1) 88-95;
  • You have access
    The effect of enzyme induction and inhibition on the disposition of the xanthine-related nootropic drug ethimizol in perfused liver and hepatocytes of rats.
    M Kukan, S Bezek, M Stefek, T Trnovec, M Durisová and L B Piotrovskiy
    Drug Metabolism and Disposition January 1990, 18 (1) 96-101;
  • You have access
    Placental transfer, tissue distribution, and pharmacokinetics of cyclosporine in the pregnant rabbit.
    L Sangalli, A Bortolotti, F Passerini and M Bonati
    Drug Metabolism and Disposition January 1990, 18 (1) 102-106;
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    Metabolism of prostaglandin F2 alpha in sheep.
    V Dimov and K Gréen
    Drug Metabolism and Disposition January 1990, 18 (1) 107-114;
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    The metabolism and disposition of 14C-fenofibrate in human volunteers.
    A Weil, J Caldwell and M Strolin-Benedetti
    Drug Metabolism and Disposition January 1990, 18 (1) 115-120;
  • You have access
    Drug interaction. Effects of salicylate on pharmacokinetics of valproic acid in rats.
    H Y Yu, Y Z Shen, Y Sugiyama and M Hanano
    Drug Metabolism and Disposition January 1990, 18 (1) 121-126;
  • You have access
    Pharmacokinetic interaction between ethanol and nitrendipine in the rat: role of hypothermia as a contributing mechanism.
    K M Boje and H L Fung
    Drug Metabolism and Disposition January 1990, 18 (1) 127-129;
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In this issue

Drug Metabolism and Disposition
Vol. 18, Issue 1
1 Jan 1990
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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