Drug Metabolism and Disposition: 18 (1)

January 01, 1990; Volume 18,Issue 1

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Pharmacokinetics and metabolism of the pharmacologically active 4'-hydroxylated metabolite of propranolol in the dog.
D D Christ, U K Walle, J E Oatis and T Walle

Drug Metabolism and Disposition January 1990, 18 (1) 1-4;
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Metabolism of chloronitrobenzenes by isolated rat hepatocytes.
D E Rickert and S D Held

Drug Metabolism and Disposition January 1990, 18 (1) 5-9;
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Effect of microsomal enzyme inducers on biliary and urinary excretion of acetaminophen metabolites in rats. Decreased hepatobiliary and increased hepatovascular transport of acetaminophen-glucuronide after microsomal enzyme induction.
Z Gregus, C Madhu and C D Klaassen

Drug Metabolism and Disposition January 1990, 18 (1) 10-19;
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Comparative studies of the in vitro metabolism and covalent binding of 14C-benzene by liver slices and microsomal fraction of mouse, rat, and human.
J I Brodfuehrer, D E Chapman, T J Wilke and G Powis

Drug Metabolism and Disposition January 1990, 18 (1) 20-27;
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Structural characterization of urinary metabolites of the antiarrhythmic drug encainide in human subjects.
H K Jajoo, R F Mayol, J A LaBudde and I A Blair

Drug Metabolism and Disposition January 1990, 18 (1) 28-35;
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Azoreduction of dimethylaminoazobenzene (DAB) in primary cultures of rat hepatocytes. Effect of hypolipidemic agents.
A M Stoddart and W G Levine

Drug Metabolism and Disposition January 1990, 18 (1) 36-41;
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Pharmacokinetics of disopyramide in the dog. Importance of mono-N-dealkylated metabolite kinetics in assessing pharmacokinetic modeling of the parent drug.
C S Cook, P R Gwilt, K Kowalski, S Gupta, J Oppermann and A Karim

Drug Metabolism and Disposition January 1990, 18 (1) 42-49;
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Purification and characterization of human kidney cytosolic cysteine conjugate beta-lyase activity.
L H Lash, R M Nelson, R A Van Dyke and M W Anders

Drug Metabolism and Disposition January 1990, 18 (1) 50-54;
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Pharmacokinetics of prednisolone and its local anti-inflammatory steroid-21-oate ester derivatives. In vitro and in vivo comparative study.
S M al-Habet, I B Taraporewala and H J Lee

Drug Metabolism and Disposition January 1990, 18 (1) 55-60;
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Thiol-mediated catalysis of nitroglycerin degradation by serum proteins. Increase in metabolism was not accompanied by S-nitrosothiol production.
S Chong and H L Fung

Drug Metabolism and Disposition January 1990, 18 (1) 61-67;
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Isolation and identification of a novel human metabolite of cyclosporin A: dihydro-CsA M17.
G P Meier, S B Park, G C Yee and D J Gmur

Drug Metabolism and Disposition January 1990, 18 (1) 68-71;
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Phenytoin disposition in the pregnant rat. Dose-dependent studies and salicylate effects.
P A Cleveland and C T Ueda

Drug Metabolism and Disposition January 1990, 18 (1) 72-79;
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A reversible clearance model for the enterohepatic circulation of drug and conjugate metabolite pair.
R L Semmes and D D Shen

Drug Metabolism and Disposition January 1990, 18 (1) 80-87;
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Disposition of ethimizol, a xanthine-related nootropic drug, in perfused rat liver and isolated hepatocytes.
S Bezek, M Kukan, Z Kállay, T Trnovec, M Stefek and L B Piotrovskiy

Drug Metabolism and Disposition January 1990, 18 (1) 88-95;
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The effect of enzyme induction and inhibition on the disposition of the xanthine-related nootropic drug ethimizol in perfused liver and hepatocytes of rats.
M Kukan, S Bezek, M Stefek, T Trnovec, M Durisová and L B Piotrovskiy

Drug Metabolism and Disposition January 1990, 18 (1) 96-101;
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Placental transfer, tissue distribution, and pharmacokinetics of cyclosporine in the pregnant rabbit.
L Sangalli, A Bortolotti, F Passerini and M Bonati

Drug Metabolism and Disposition January 1990, 18 (1) 102-106;
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Metabolism of prostaglandin F2 alpha in sheep.
V Dimov and K Gréen

Drug Metabolism and Disposition January 1990, 18 (1) 107-114;
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The metabolism and disposition of 14C-fenofibrate in human volunteers.
A Weil, J Caldwell and M Strolin-Benedetti

Drug Metabolism and Disposition January 1990, 18 (1) 115-120;
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Drug interaction. Effects of salicylate on pharmacokinetics of valproic acid in rats.
H Y Yu, Y Z Shen, Y Sugiyama and M Hanano

Drug Metabolism and Disposition January 1990, 18 (1) 121-126;
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Pharmacokinetic interaction between ethanol and nitrendipine in the rat: role of hypothermia as a contributing mechanism.
K M Boje and H L Fung

Drug Metabolism and Disposition January 1990, 18 (1) 127-129;

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