Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Drug Metabolism & Disposition
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Drug Metabolism & Disposition

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit dmd on Facebook
  • Follow dmd on Twitter
  • Follow ASPET on LinkedIn

Table of Contents

November 01, 1990; Volume 18,Issue 6
  • You have access
    The 1988 Bernard B. Brodie Award lecture. Functional diversity of hepatic cytochromes P-450.
    W Levin
    Drug Metabolism and Disposition November 1990, 18 (6) 824-830;
  • You have access
    Pharmacokinetics and tissue distribution of the renin inhibitor N-(2-(R)-benzyl-3-tert-butyl-sulfonyl-propionyl)-His-ChacVal-n-butylami ne in marmosets.
    F Cumin, C Schnell, P Richert, F Raschdorf, A Probst, K Schmid, J M Wood and M de Gasparo
    Drug Metabolism and Disposition November 1990, 18 (6) 831-835;
  • You have access
    Dose-dependent pharmacokinetics of MK-417, a potent carbonic anhydrase inhibitor, in rabbits following single and multiple doses.
    J H Lin, I W Chen, E H Ulm, J R Gehret and D E Duggan
    Drug Metabolism and Disposition November 1990, 18 (6) 836-841;
  • You have access
    Disposition and metabolism of carbovir in mice dosed intravenously or orally.
    S M el Dareer, K F Tillery, L M Rose, R F Struck and D L Hill
    Drug Metabolism and Disposition November 1990, 18 (6) 842-845;
  • You have access
    Disposition of amiodarone and its proximate metabolite, desethylamiodarone, in the dog for oral administration of single-dose and short-term drug regimens.
    J F Brien, S Jimmo, F J Brennan, P W Armstrong and H Abdollah
    Drug Metabolism and Disposition November 1990, 18 (6) 846-851;
  • You have access
    Pharmacokinetics, N1-glucuronidation, and N4-acetylation of sulfa-6-monomethoxine in humans.
    T B Vree, E W Beneken Kolmer, Y A Hekster, M Shimoda, M Ono and T Miura
    Drug Metabolism and Disposition November 1990, 18 (6) 852-858;
  • You have access
    Progesterone metabolism in hepatic microsomes. Effect of the cytochrome P-450 inhibitor, ketoconazole, and the NADPH 5 alpha-reductase inhibitor, 4-MA, upon the metabolic profile in human, monkey, dog, and rat.
    D C Swinney
    Drug Metabolism and Disposition November 1990, 18 (6) 859-865;
  • You have access
    Metabolism of citral, an alpha,beta-unsaturated aldehyde, in male F344 rats.
    J J Diliberto, P Srinivas, D Overstreet, G Usha, L T Burka and L S Birnbaum
    Drug Metabolism and Disposition November 1990, 18 (6) 866-875;
  • You have access
    Metabolism of diphenyl sulfoxide in perfused guinea pig liver. Involvement of aldehyde oxidase as a sulfoxide reductase.
    S Yoshihara and K Tatsumi
    Drug Metabolism and Disposition November 1990, 18 (6) 876-881;
  • You have access
    Life span profiles of glutathione and acetaminophen detoxification.
    T S Chen, J P Richie and C A Lang
    Drug Metabolism and Disposition November 1990, 18 (6) 882-887;
  • You have access
    Metabolism of the anticonvulsant agent zonisamide in the rat.
    D D Stiff and M A Zemaitis
    Drug Metabolism and Disposition November 1990, 18 (6) 888-894;
  • You have access
    Taxol metabolism. Isolation and identification of three major metabolites of taxol in rat bile.
    B Monsarrat, E Mariel, S Cros, M Garès, D Guénard, F Guéritte-Voegelein and M Wright
    Drug Metabolism and Disposition November 1990, 18 (6) 895-901;
  • You have access
    Physiological pharmacokinetics of a new muscle-relaxant, inaperisone, combined with its pharmacological effect on blood flow rate.
    O Nagata, M Murata, H Kato, T Terasaki, H Sato and A Tsuji
    Drug Metabolism and Disposition November 1990, 18 (6) 902-910;
  • You have access
    Metabolism of hexafluoropropene. Evidence for bioactivation by glutathione conjugate formation in the kidney.
    M Koob and W Dekant
    Drug Metabolism and Disposition November 1990, 18 (6) 911-916;
  • You have access
    In vivo metabolites of S-(2-benzothiazolyl)-L-cysteine as markers of in vivo cysteine conjugate beta-lyase and thiol glucuronosyl transferase activities.
    A A Elfarra and I Y Hwang
    Drug Metabolism and Disposition November 1990, 18 (6) 917-922;
  • You have access
    Metabolism and disposition of the dopamine agonist 2-(N-propyl-N-2-thienylethylamino)-5-hydroxytetralin in conscious monkeys after subsequent i.v. oral, and ocular administration.
    T K Gerding, B F Drenth, R A de Zeeuw, P G Tepper and A S Horn
    Drug Metabolism and Disposition November 1990, 18 (6) 923-928;
  • You have access
    Metabolism and covalent binding of [14C]toluene by human and rat liver microsomal fractions and liver slices.
    D E Chapman, T J Moore, S R Michener and G Powis
    Drug Metabolism and Disposition November 1990, 18 (6) 929-936;
  • You have access
    Diflunisal disposition. Role of gastric absorption in the development of mucosal damage and anti-inflammatory potency in rodents.
    B Nuernberg, I Szelenyi, H T Schneider and K Brune
    Drug Metabolism and Disposition November 1990, 18 (6) 937-942;
  • You have access
    Cytochrome P-450 isozymes in metabolic activation of delta 9-tetrahydrocannabinol by rat liver microsomes.
    S Narimatsu, K Watanabe, T Matsunaga, I Yamamoto, S Imaoka, Y Funae and H Yoshimura
    Drug Metabolism and Disposition November 1990, 18 (6) 943-948;
  • You have access
    The metabolism of etintidine in rat, dog, and human.
    F A Wong, J R Lloyd and D W Graden
    Drug Metabolism and Disposition November 1990, 18 (6) 949-953;
  • You have access
    Ciprofloxacin does not impair the elimination of diazepam in humans.
    W J Wijnands, J F Trooster, P C Teunissen, H A Cats and T B Vree
    Drug Metabolism and Disposition November 1990, 18 (6) 954-957;
  • You have access
    Identification of N-acetyl-S-(2,5-dihydroxyphenyl)-L-cysteine as a urinary metabolite of benzene, phenol, and hydroquinone.
    D E Nerland and W M Pierce
    Drug Metabolism and Disposition November 1990, 18 (6) 958-961;
  • You have access
    Effects of sodium salicylate on elimination kinetics of indomethacin and bile production in dogs.
    W S Beck, K Dietzel, G Geisslinger, H Engler, H Vergin and K Brune
    Drug Metabolism and Disposition November 1990, 18 (6) 962-967;
  • You have access
    Disposition in humans of racemic picenadol, an opioid analgesic.
    P M Franz, S L Anliker, J T Callaghan, K A DeSante, P H Dhahir, R L Nelson and A Rubin
    Drug Metabolism and Disposition November 1990, 18 (6) 968-973;
  • You have access
    Isotope effect studies on the mechanism of the cytochrome P-450IIA1-catalyzed formation of delta 6-testosterone from testosterone.
    K R Korzekwa, W F Trager, K Nagata, A Parkinson and J R Gillette
    Drug Metabolism and Disposition November 1990, 18 (6) 974-979;
  • You have access
    Metabolic disposition of trimetrexate, a nonclassical dihydrofolate reductase inhibitor, in rat and dog.
    B K Wong, T F Woolf, T Chang and L R Whitfield
    Drug Metabolism and Disposition November 1990, 18 (6) 980-986;
  • You have access
    Pharmacokinetics of propafenone enantiomers in rats.
    R Mehvar
    Drug Metabolism and Disposition November 1990, 18 (6) 987-991;
  • You have access
    Oxidative defluorination of 1,1,1,2-tetrafluoroethane by rat liver microsomes.
    M J Olson, C A Reidy, J T Johnson and T C Pederson
    Drug Metabolism and Disposition November 1990, 18 (6) 992-998;
  • You have access
    The use of pig hepatocytes to study the biotransformation of beta-nortestosterone by pigs. Identification of glucuronidated 15 alpha-hydroxy-norandrostenedione as an important in vitro and in vivo metabolite.
    L A Hoogenboom, M C Berghmans, A Van Veldhuizen and H A Kuiper
    Drug Metabolism and Disposition November 1990, 18 (6) 999-1004;
  • You have access
    Quinolone inhibition of cytochrome P-450-dependent caffeine metabolism in human liver microsomes.
    U Fuhr, T Wolff, S Harder, P Schymanski and A H Staib
    Drug Metabolism and Disposition November 1990, 18 (6) 1005-1010;
  • You have access
    Pulmonary elimination and metabolism of 5-fluoro-2'-deoxyuridine in isolated perfused rat lung and lung slices.
    H Foth, J Hellkamp, E M Kunellis and G F Kahl
    Drug Metabolism and Disposition November 1990, 18 (6) 1011-1017;
  • You have access
    Plasma elimination and urinary excretion of methapyrilene in the rat.
    D W Kelly, C L Holder, W A Korfmacher and W Slikker
    Drug Metabolism and Disposition November 1990, 18 (6) 1018-1024;
  • You have access
    Metabolism of antiparkinson agent dopazinol by rat liver microsomes.
    K P Vyas, P H Kari, H G Ramjit, S M Pitzenberger and M Hichens
    Drug Metabolism and Disposition November 1990, 18 (6) 1025-1030;
  • You have access
    Three N-aralkylated derivatives of 1-aminobenzotriazole as potent and isozyme-selective, mechanism-based inhibitors of guinea pig pulmonary cytochrome P-450 in vitro.
    K J Woodcroft, E W Szczepan, L C Knickle and J R Bend
    Drug Metabolism and Disposition November 1990, 18 (6) 1031-1037;
  • You have access
    Formation and reversibility of S-linked conjugates of N-(1-methyl-3,3-diphenylpropyl)isocyanate, an in vivo metabolite of N-(1-methyl-3,3-diphenylpropyl)formamaide, in rats.
    A E Mutlib, R E Talaat, J G Slatter and F S Abbott
    Drug Metabolism and Disposition November 1990, 18 (6) 1038-1045;
  • You have access
    In vitro metabolism of (-)-cis-3-[2-hydroxy-4-(1,1-dimethylheptyl) phenyl]-trans-4-(3-hydroxypropyl) cyclohexanol, a synthetic bicyclic cannabinoid analog.
    B F Thomas and B R Martin
    Drug Metabolism and Disposition November 1990, 18 (6) 1046-1054;
  • You have access
    Species comparison of pharmacokinetics and metabolism of diltiazem in humans, dogs, rabbits, and rats.
    P K Yeung, S J Mosher, M A Quilliam and T J Montague
    Drug Metabolism and Disposition November 1990, 18 (6) 1055-1059;
  • You have access
    Pharmacokinetics of flobufen and its main active metabolite in the rat.
    R Lapka, S Smolík and V Rejholec
    Drug Metabolism and Disposition November 1990, 18 (6) 1060-1064;
  • You have access
    In vitro metabolism of cannabichromene in seven common laboratory animals.
    N K Brown and D J Harvey
    Drug Metabolism and Disposition November 1990, 18 (6) 1065-1070;
  • You have access
    Systemic pharmacokinetics of acetylenic retinoids in rats.
    S S Liu, R Sandri and D D Tang-Liu
    Drug Metabolism and Disposition November 1990, 18 (6) 1071-1077;
  • You have access
    The pharmacokinetics of (-)-carbovir in rats. Evidence for nonlinear elimination.
    K R Brouwer, R L St Claire, J Lagarde, J E Patanella, J S Walsh and G T Miwa
    Drug Metabolism and Disposition November 1990, 18 (6) 1078-1083;
  • You have access
    The metabolism and excretion of carbovir, a carbocyclic nucleoside, in the rat.
    J S Walsh, J E Patanella, S E Unger, K R Brouwer and G T Miwa
    Drug Metabolism and Disposition November 1990, 18 (6) 1084-1091;
  • You have access
    Identification of a glucuronide conjugate of the carbocyclic nucleoside, carbovir, isolated from marmoset urine.
    J E Patanella, J S Walsh, S E Unger, G T Miwa, P S Parry, M J Daniel and G L Evans
    Drug Metabolism and Disposition November 1990, 18 (6) 1092-1095;
  • You have access
    Identification of phenolic doxepin glucuronides from patient urine and rat bile.
    Y Z Shu, J W Hubbard, G McKay and K K Midha
    Drug Metabolism and Disposition November 1990, 18 (6) 1096-1099;
  • You have access
    Characterization of a quaternary, N-glucuronide metabolite of the imidazole antifungal, tioconazole.
    P V Macrae, M Kirrs, F S Pullen and M H Tarbit
    Drug Metabolism and Disposition November 1990, 18 (6) 1100-1102;
  • You have access
    The metabolism of ofloxacin in humans.
    F A Wong and S C Flor
    Drug Metabolism and Disposition November 1990, 18 (6) 1103-1104;
  • You have access
    The metabolic fate of 13-cis-retinoic acid in mouse skin microsomal preparations.
    N Oldfield
    Drug Metabolism and Disposition November 1990, 18 (6) 1105-1107;
Back to top
PreviousNext

In this issue

Drug Metabolism and Disposition
Vol. 18, Issue 6
1 Nov 1990
  • Table of Contents
  • Index by author
  • Back Matter (PDF)
Sign up for alerts
  • Most Read
Loading
  • Cannabinoid Metabolites as CYP450 Inhibitors
  • Physiology of the Neonatal Gastrointestinal System
  • Pharmacokinetics and Disposition of Biologics
  • Switch from CAR to PXR in the Presence of EGF
  • Alternative P450 Splicing Redirects Human Drug Metabolism
More...
Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About DMD
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-009X (Online)

Copyright © 2022 by the American Society for Pharmacology and Experimental Therapeutics