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Drug Metabolism & Disposition

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Table of Contents

November 01, 1991; Volume 19,Issue 6
  • You have access
    Best Paper Award for 1990.
    Drug Metabolism and Disposition November 1991, 19 (6) 1015;
  • You have access
    Differential effects of proteinase K on the components of the liver microsomal cytochrome P-450 mixed function oxidase system.
    T L Shen, Z P Zhuang, R McCauley, D Putt and P F Hollenberg
    Drug Metabolism and Disposition November 1991, 19 (6) 1016-1021;
  • You have access
    Effect of perfusion rate on the local disposition of cefixime in liver perfusion system based on two-compartment dispersion model.
    Y Yano, K Yamaoka, H Yasui and T Nakagawa
    Drug Metabolism and Disposition November 1991, 19 (6) 1022-1027;
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    Identification and structure characterization of S-containing metabolites of 3-tert-butyl-4-hydroxyanisole in rat urine and liver microsomes.
    K Tajima, M Hashizaki, K Yamamoto and T Mizutani
    Drug Metabolism and Disposition November 1991, 19 (6) 1028-1033;
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    Sex differences in the pharmacokinetics of recombinant human granulocyte colony-stimulating factor in the rat.
    H Tanaka and T Kaneko
    Drug Metabolism and Disposition November 1991, 19 (6) 1034-1039;
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    Cardioselectivity of alpha-tocopherol analogues, with free radical scavenger activity, in the rat.
    J Dow, M A Petty, J M Grisar, E R Wagner and K D Haegele
    Drug Metabolism and Disposition November 1991, 19 (6) 1040-1045;
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    Human microsomal N-oxidative metabolism of cocaine.
    S M Roberts, R D Harbison and R C James
    Drug Metabolism and Disposition November 1991, 19 (6) 1046-1051;
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    Age-related changes in disposition and metabolism of benzene in male C57BL/6N mice.
    T F McMahon and L S Birnbaum
    Drug Metabolism and Disposition November 1991, 19 (6) 1052-1057;
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    Elimination of the antiviral drug 5-ethyl-2'-deoxyuridine by the isolated perfused rat liver.
    J M Joly and W M Williams
    Drug Metabolism and Disposition November 1991, 19 (6) 1058-1065;
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    Metabolism and disposition of diethylene glycol in rat and dog.
    J M Mathews, M K Parker and H B Matthews
    Drug Metabolism and Disposition November 1991, 19 (6) 1066-1070;
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    Human liver arylamine N-sulfotransferase activity. Thermostable phenol sulfotransferase catalyzes the N-sulfation of 2-naphthylamine.
    J S Hernández, S P Powers and R M Weinshilboum
    Drug Metabolism and Disposition November 1991, 19 (6) 1071-1079;
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    Stereoselective degradation of the fenoprofen acyl glucuronide enantiomers and irreversible binding to plasma protein.
    C Volland, H Sun, J Dammeyer and L Z Benet
    Drug Metabolism and Disposition November 1991, 19 (6) 1080-1086;
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    Renal tubular transport of morphine, morphine-6-glucuronide, and morphine-3-glucuronide in the isolated perfused rat kidney.
    J T Van Crugten, B C Sallustio, R L Nation and A A Somogyi
    Drug Metabolism and Disposition November 1991, 19 (6) 1087-1092;
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    Pharmacokinetic interaction between verapamil and metoprolol in the dog. Stereochemical aspects.
    S S Murthy, W L Nelson, D D Shen, J M Power, C M Cahill and A J McLean
    Drug Metabolism and Disposition November 1991, 19 (6) 1093-1100;
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    Metabolism and disposition of cyclohexanone oxime in male F-344 rats.
    D Parmar and L T Burka
    Drug Metabolism and Disposition November 1991, 19 (6) 1101-1107;
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    Oxidation of ethylene glycol to formaldehyde by rat liver microsomes. Role of cytochrome P-450 and reactive oxygen species.
    E Kukiełka and A I Cederbaum
    Drug Metabolism and Disposition November 1991, 19 (6) 1108-1115;
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    Felbamate pharmacokinetics in the rat, rabbit, and dog.
    V E Adusumalli, J T Yang, K K Wong, N Kucharczyk and R D Sofia
    Drug Metabolism and Disposition November 1991, 19 (6) 1116-1125;
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    Felbamate metabolism in the rat, rabbit, and dog.
    J T Yang, V E Adusumalli, K K Wong, N Kucharczyk and R D Sofia
    Drug Metabolism and Disposition November 1991, 19 (6) 1126-1134;
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    Felbamate in vitro metabolism by rat liver microsomes.
    V E Adusumalli, K K Wong, N Kucharczyk and R D Sofia
    Drug Metabolism and Disposition November 1991, 19 (6) 1135-1138;
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    The disposition and metabolism of [14C]piritrexim in dogs after intravenous and oral administration.
    J L Woolley, D V Deangelis, M E Grace, S H Liao, R C Crouch and C W Sigel
    Drug Metabolism and Disposition November 1991, 19 (6) 1139-1146;
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    Tissue distribution and in vivo immunosuppressive activity of liposomal cyclosporine.
    K Vadiei, G Lopez-Berestein, R Perez-Soler and D R Luke
    Drug Metabolism and Disposition November 1991, 19 (6) 1147-1151;
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    Characterization of a rat liver glucuronosyltransferase that glucuronidates the selective D1 antagonist, SCH 23390, and other benzazepines.
    C E Tedford, V B Ruperto and A Barnett
    Drug Metabolism and Disposition November 1991, 19 (6) 1152-1159;
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    Synthesis and identification of a novel tetrazole metabolite of the angiotensin II receptor antagonist DuP 753.
    R A Stearns, G A Doss, R R Miller and S H Chiu
    Drug Metabolism and Disposition November 1991, 19 (6) 1160-1162;
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    Microsomal hydroxylation of triallate: identification of a 2-chloroacrylate glutathione conjugate using heteronuclear multiple quantum coherence NMR spectroscopy.
    A G Hackett, J J Kotyk, H Fujiwara and E W Logusch
    Drug Metabolism and Disposition November 1991, 19 (6) 1163-1165;
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In this issue

Drug Metabolism and Disposition
Vol. 19, Issue 6
1 Nov 1991
  • Table of Contents
  • Index by author
  • Back Matter (PDF)
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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