Drug Metabolism and Disposition: 20 (1)

January 01, 1992; Volume 20,Issue 1

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Catalytic and immunologic similarities between monkey and human liver cytochrome P-450db1 (human cytochrome P-450 2D6).
S V Otton, R F Tyndale, D Wu, T Inaba, W Kalow and E M Sellers

Drug Metabolism and Disposition January 1992, 20 (1) 1-5;
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Pharmacokinetics of 2-ethyl-1,3-hexanediol. II. Nonsystemic disposition following single percutaneous or peroral doses in Fischer 344 rats.
S W Frantz, J L Beskitt, C M Grosse, M J Tallant and B Ballantyne

Drug Metabolism and Disposition January 1992, 20 (1) 6-18;
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Comparisons of hepatic and renal cytochromes P-450-dependent monooxygenases from fuzzy and Sprague-Dawley rats.
E Cheriathundam, R Almirez and A P Alvares

Drug Metabolism and Disposition January 1992, 20 (1) 19-22;
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Pharmacokinetic evaluation of two human epidermal growth factors (hEGF51 and hEGF53) in rats.
B S Kuo, W F Kusmik, J C Poole, S H Elsea, J Chang and K K Hwang

Drug Metabolism and Disposition January 1992, 20 (1) 23-30;
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Characterization of human liver cytochromes P-450 involved in theophylline metabolism.
M A Sarkar, C Hunt, P S Guzelian and H T Karnes

Drug Metabolism and Disposition January 1992, 20 (1) 31-37;
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Microbial models of mammalian metabolism. Biotransformations of N-methylcarbazole using the fungus Cunninghamella echinulata.
W Yang and P J Davis

Drug Metabolism and Disposition January 1992, 20 (1) 38-46;
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Pharmacokinetic evaluation of (-)-6-aminocarbovir as a prodrug for (-)-carbovir in rats.
C L Zimmerman, R P Remmel, S S Ibrahim, S A Beers and R Vince

Drug Metabolism and Disposition January 1992, 20 (1) 47-51;
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Deacetylation of cinobufagin by rat liver.
L Zhang, K Aoki, T Yoshida and Y Kuroiwa

Drug Metabolism and Disposition January 1992, 20 (1) 52-55;
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Characterization of the cytochrome P-450 gene family responsible for the N-dealkylation of the ergot alkaloid CQA 206-291 in humans.
S E Ball, G Maurer, M Zollinger, M Ladona and A E Vickers

Drug Metabolism and Disposition January 1992, 20 (1) 56-63;
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The urinary metabolic profile of metyrapone in the rat. Identification of two novel isomeric metyrapol N-oxide metabolites.
J I Usansky and L A Damani

Drug Metabolism and Disposition January 1992, 20 (1) 64-69;
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Disposition of 1-naphthol in the channel catfish (Ictalurus punctatus).
G R Stehly and S M Plakas

Drug Metabolism and Disposition January 1992, 20 (1) 70-73;
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Effect of H2-receptor antagonists on rat liver cytosolic acetyl CoA:arylamine N-acetyltransferase activity.
C K Svensson and M Tomilo

Drug Metabolism and Disposition January 1992, 20 (1) 74-78;
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Cytochrome P-450 isozymes involved in the oxidative metabolism of delta 9-tetrahydrocannabinol by liver microsomes of adult female rats.
S Narimatsu, K Watanabe, T Matsunaga, I Yamamoto, S Imaoka, Y Funae and H Yoshimura

Drug Metabolism and Disposition January 1992, 20 (1) 79-83;
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Felbamate metabolism in pediatric and adult beagle dogs.
J T Yang, M Morris, K K Wong, N Kucharczyk and R D Sofia

Drug Metabolism and Disposition January 1992, 20 (1) 84-88;
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Metabolism of the anticoagulant peptide, MDL 28,050, in rats.
M P Knadler, B L Ackermann, J E Coutant and G H Hurst

Drug Metabolism and Disposition January 1992, 20 (1) 89-95;
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Identification of cytochrome P-450IIB1 as a cocaine-bioactivating isoform in rat hepatic microsomes and in cultured rat hepatocytes.
U A Boelsterli, A Lanzotti, C Göldlin and M Oertle

Drug Metabolism and Disposition January 1992, 20 (1) 96-101;
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Disposition of the novel serotonin agonist, LY228729, in monkeys and rats.
S P Swanson and J Catlow

Drug Metabolism and Disposition January 1992, 20 (1) 102-107;
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Substituted pyridines: nonsteroidal inhibitors of human placental aromatase cytochrome P-450.
A D Vaz, M J Coon, H Peegel and K M Menon

Drug Metabolism and Disposition January 1992, 20 (1) 108-112;
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Pharmacokinetics and tissue distribution of 2-fluoro-beta-alanine in rats. Potential relevance to toxicity pattern of 5-fluorouracil.
R W Zhang, S J Soong, T P Liu, S Barnes and S B Diasio

Drug Metabolism and Disposition January 1992, 20 (1) 113-119;
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Comparative metabolism and covalent binding of procainamide by human leukocytes.
J Uetrecht and B Sokoluk

Drug Metabolism and Disposition January 1992, 20 (1) 120-123;
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Isolation and identification of the major urinary metabolite of N-methylpyrrolidinone in the rat.
D A Wells, A A Hawi and G A Digenis

Drug Metabolism and Disposition January 1992, 20 (1) 124-126;
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Metabolism of enflurane in dogs.
T Sakai, M Takaori and H Yoshida

Drug Metabolism and Disposition January 1992, 20 (1) 127-129;
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Formation of a carbamoyl glucuronide conjugate of carvedilol in vitro using dog and rat liver microsomes.
W H Schaefer

Drug Metabolism and Disposition January 1992, 20 (1) 130-133;
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Substrate specificity and other characteristics of a novel aldehyde dehydrogenase present in female DBA/2 mouse liver.
N S Zhoo and N E Sladek

Drug Metabolism and Disposition January 1992, 20 (1) 134-136;

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