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Drug Metabolism & Disposition

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Table of Contents

January 01, 1992; Volume 20,Issue 1
  • You have access
    Catalytic and immunologic similarities between monkey and human liver cytochrome P-450db1 (human cytochrome P-450 2D6).
    S V Otton, R F Tyndale, D Wu, T Inaba, W Kalow and E M Sellers
    Drug Metabolism and Disposition January 1992, 20 (1) 1-5;
  • You have access
    Pharmacokinetics of 2-ethyl-1,3-hexanediol. II. Nonsystemic disposition following single percutaneous or peroral doses in Fischer 344 rats.
    S W Frantz, J L Beskitt, C M Grosse, M J Tallant and B Ballantyne
    Drug Metabolism and Disposition January 1992, 20 (1) 6-18;
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    Comparisons of hepatic and renal cytochromes P-450-dependent monooxygenases from fuzzy and Sprague-Dawley rats.
    E Cheriathundam, R Almirez and A P Alvares
    Drug Metabolism and Disposition January 1992, 20 (1) 19-22;
  • You have access
    Pharmacokinetic evaluation of two human epidermal growth factors (hEGF51 and hEGF53) in rats.
    B S Kuo, W F Kusmik, J C Poole, S H Elsea, J Chang and K K Hwang
    Drug Metabolism and Disposition January 1992, 20 (1) 23-30;
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    Characterization of human liver cytochromes P-450 involved in theophylline metabolism.
    M A Sarkar, C Hunt, P S Guzelian and H T Karnes
    Drug Metabolism and Disposition January 1992, 20 (1) 31-37;
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    Microbial models of mammalian metabolism. Biotransformations of N-methylcarbazole using the fungus Cunninghamella echinulata.
    W Yang and P J Davis
    Drug Metabolism and Disposition January 1992, 20 (1) 38-46;
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    Pharmacokinetic evaluation of (-)-6-aminocarbovir as a prodrug for (-)-carbovir in rats.
    C L Zimmerman, R P Remmel, S S Ibrahim, S A Beers and R Vince
    Drug Metabolism and Disposition January 1992, 20 (1) 47-51;
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    Deacetylation of cinobufagin by rat liver.
    L Zhang, K Aoki, T Yoshida and Y Kuroiwa
    Drug Metabolism and Disposition January 1992, 20 (1) 52-55;
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    Characterization of the cytochrome P-450 gene family responsible for the N-dealkylation of the ergot alkaloid CQA 206-291 in humans.
    S E Ball, G Maurer, M Zollinger, M Ladona and A E Vickers
    Drug Metabolism and Disposition January 1992, 20 (1) 56-63;
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    The urinary metabolic profile of metyrapone in the rat. Identification of two novel isomeric metyrapol N-oxide metabolites.
    J I Usansky and L A Damani
    Drug Metabolism and Disposition January 1992, 20 (1) 64-69;
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    Disposition of 1-naphthol in the channel catfish (Ictalurus punctatus).
    G R Stehly and S M Plakas
    Drug Metabolism and Disposition January 1992, 20 (1) 70-73;
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    Effect of H2-receptor antagonists on rat liver cytosolic acetyl CoA:arylamine N-acetyltransferase activity.
    C K Svensson and M Tomilo
    Drug Metabolism and Disposition January 1992, 20 (1) 74-78;
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    Cytochrome P-450 isozymes involved in the oxidative metabolism of delta 9-tetrahydrocannabinol by liver microsomes of adult female rats.
    S Narimatsu, K Watanabe, T Matsunaga, I Yamamoto, S Imaoka, Y Funae and H Yoshimura
    Drug Metabolism and Disposition January 1992, 20 (1) 79-83;
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    Felbamate metabolism in pediatric and adult beagle dogs.
    J T Yang, M Morris, K K Wong, N Kucharczyk and R D Sofia
    Drug Metabolism and Disposition January 1992, 20 (1) 84-88;
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    Metabolism of the anticoagulant peptide, MDL 28,050, in rats.
    M P Knadler, B L Ackermann, J E Coutant and G H Hurst
    Drug Metabolism and Disposition January 1992, 20 (1) 89-95;
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    Identification of cytochrome P-450IIB1 as a cocaine-bioactivating isoform in rat hepatic microsomes and in cultured rat hepatocytes.
    U A Boelsterli, A Lanzotti, C Göldlin and M Oertle
    Drug Metabolism and Disposition January 1992, 20 (1) 96-101;
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    Disposition of the novel serotonin agonist, LY228729, in monkeys and rats.
    S P Swanson and J Catlow
    Drug Metabolism and Disposition January 1992, 20 (1) 102-107;
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    Substituted pyridines: nonsteroidal inhibitors of human placental aromatase cytochrome P-450.
    A D Vaz, M J Coon, H Peegel and K M Menon
    Drug Metabolism and Disposition January 1992, 20 (1) 108-112;
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    Pharmacokinetics and tissue distribution of 2-fluoro-beta-alanine in rats. Potential relevance to toxicity pattern of 5-fluorouracil.
    R W Zhang, S J Soong, T P Liu, S Barnes and S B Diasio
    Drug Metabolism and Disposition January 1992, 20 (1) 113-119;
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    Comparative metabolism and covalent binding of procainamide by human leukocytes.
    J Uetrecht and B Sokoluk
    Drug Metabolism and Disposition January 1992, 20 (1) 120-123;
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    Isolation and identification of the major urinary metabolite of N-methylpyrrolidinone in the rat.
    D A Wells, A A Hawi and G A Digenis
    Drug Metabolism and Disposition January 1992, 20 (1) 124-126;
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    Metabolism of enflurane in dogs.
    T Sakai, M Takaori and H Yoshida
    Drug Metabolism and Disposition January 1992, 20 (1) 127-129;
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    Formation of a carbamoyl glucuronide conjugate of carvedilol in vitro using dog and rat liver microsomes.
    W H Schaefer
    Drug Metabolism and Disposition January 1992, 20 (1) 130-133;
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    Substrate specificity and other characteristics of a novel aldehyde dehydrogenase present in female DBA/2 mouse liver.
    N S Zhoo and N E Sladek
    Drug Metabolism and Disposition January 1992, 20 (1) 134-136;
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In this issue

Drug Metabolism and Disposition
Vol. 20, Issue 1
1 Jan 1992
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Most Cited
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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