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Drug Metabolism & Disposition

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Table of Contents

March 01, 1992; Volume 20,Issue 2
  • You have access
    Influence of P-4502E1 induction on benzene metabolism in rat hepatocytes and on biliary metabolite excretion.
    D Schrenk, M Ingelman-Sundberg and K W Bock
    Drug Metabolism and Disposition March 1992, 20 (2) 137-141;
  • You have access
    Identification of the antibiotic hops component, colupulone, as an inducer of hepatic cytochrome P-4503A in the mouse.
    G J Mannering, J A Shoeman and L B Deloria
    Drug Metabolism and Disposition March 1992, 20 (2) 142-147;
  • You have access
    Disposition and pharmacokinetics of [14C]finasteride after oral administration in humans.
    J R Carlin, P Höglund, L O Eriksson, P Christofalo, S L Gregoire, A M Taylor and K E Andersson
    Drug Metabolism and Disposition March 1992, 20 (2) 148-155;
  • You have access
    Methacrylonitrile: in vivo metabolism to cyanide in rats, mice, and gerbils.
    M Y Farooqui, R G Diaz and J H Deleon
    Drug Metabolism and Disposition March 1992, 20 (2) 156-160;
  • You have access
    Identification of biliary metabolites of m-dichlorobenzene in rats.
    R Kimura, N Ohishi, Y Kato, S Yamada and M Sato
    Drug Metabolism and Disposition March 1992, 20 (2) 161-171;
  • You have access
    Glucuronidation of the dopamine D-1 receptor antagonists NNC 0756 and NNC 0772 in liver microsomes.
    K T Hansen, K F Thomsen and H Bundgaard
    Drug Metabolism and Disposition March 1992, 20 (2) 172-178;
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    Stereoselective renal tubular secretion of a new uricosuric diuretic, 6,7-dichloro-5-(N,N-dimethylsulfamoyl)-2,3-dihydro-2-benzofurancarboxyl ic acid (S-8666), in cynomolgus monkeys.
    M Nakano and S Kawahara
    Drug Metabolism and Disposition March 1992, 20 (2) 179-185;
  • You have access
    Isolation of two immunosuppressive metabolites after in vitro metabolism of rapamycin.
    U Christians, M Sattler, H M Schiebel, C Kruse, H H Radeke, A Linck and K F Sewing
    Drug Metabolism and Disposition March 1992, 20 (2) 186-191;
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    Evidence for urinary excretion of glucuronide conjugates of nicotine, cotinine, and trans-3'-hydroxycotinine in smokers.
    G D Byrd, K M Chang, J M Greene and J D deBethizy
    Drug Metabolism and Disposition March 1992, 20 (2) 192-197;
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    Comparative metabolism and disposition of furfural and furfuryl alcohol in rats.
    A A Nomeir, D M Silveira, M F McComish and M Chadwick
    Drug Metabolism and Disposition March 1992, 20 (2) 198-204;
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    Metabolism of isoniazid by activated leukocytes. Possible role in drug-induced lupus.
    A H Hofstra, S M Li-Muller and J P Uetrecht
    Drug Metabolism and Disposition March 1992, 20 (2) 205-210;
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    Systemic pharmacokinetics of acitretin, etretinate, isotretinoin, and acetylenic retinoids in guinea pigs and obese rats.
    D S Chien, R B Sandri and D S Tang-Liu
    Drug Metabolism and Disposition March 1992, 20 (2) 211-217;
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    Correlations between conceptal concentrations of all-trans-retinoic acid and dysmorphogenesis after microinjections of all-trans-retinoic acid, 13-cis-retinoic acid, all-trans-retinoyl-beta-glucuronide, or retinol in cultured whole rat embryos.
    J C Kraft and M R Juchau
    Drug Metabolism and Disposition March 1992, 20 (2) 218-225;
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    Metabolism of sodium nifurstyrenate, a veterinary antimicrobial nitrofuran, in animals and fish.
    K Tatsumi, S Kitamura, M Kato and K Hiraoka
    Drug Metabolism and Disposition March 1992, 20 (2) 226-233;
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    Availability of glycine and coenzyme A limits glycine conjugation in vivo.
    Z Gregus, T Fekete, F Varga and C D Klaassen
    Drug Metabolism and Disposition March 1992, 20 (2) 234-240;
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    Human hepatic microsomal metabolism of delta 1-tetrahydrocannabinol.
    L M Bornheim, J M Lasker and J L Raucy
    Drug Metabolism and Disposition March 1992, 20 (2) 241-246;
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    Human hepatic microsomal thiol methyltransferase. Assay conditions, biochemical properties, and correlation studies.
    T A Glauser, A L Kerremans and R M Weinshilboum
    Drug Metabolism and Disposition March 1992, 20 (2) 247-255;
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    Urinary metabolic profiles in human and rat of 1,2-dimethyl- and 1,2-diethyl-substituted 3-hydroxypyridin-4-ones.
    S Singh, R O Epemolu, P S Dobbin, G S Tilbrook, B L Ellis, L A Damani and R C Hider
    Drug Metabolism and Disposition March 1992, 20 (2) 256-261;
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    A metabolic route of omeprazole involving conjugation with glutathione identified in the rat.
    L Weidolf, K E Karlsson and I Nilsson
    Drug Metabolism and Disposition March 1992, 20 (2) 262-267;
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    Stereoselective acetonyl side chain reduction of warfarin and analogs. Partial characterization of two cytosolic carbonyl reductases.
    J J Hermans and H H Thijssen
    Drug Metabolism and Disposition March 1992, 20 (2) 268-274;
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    Guinea pig and rat hepatic microsomal metabolism of monocrotaline.
    S R Dueker, M W Lamé, D Morin, D W Wilson and H J Segall
    Drug Metabolism and Disposition March 1992, 20 (2) 275-280;
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    The metabolism of DuP 753, a nonpeptide angiotensin II receptor antagonist, by rat, monkey, and human liver slices.
    R A Stearns, R R Miller, G A Doss, P K Chakravarty, A Rosegay, G J Gatto and S H Chiu
    Drug Metabolism and Disposition March 1992, 20 (2) 281-287;
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    The influence of vitamin K3 treatment on the pharmacokinetics and metabolism of (+)-propranolol in the rat.
    H H Chow and D Lalka
    Drug Metabolism and Disposition March 1992, 20 (2) 288-294;
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    Metabolic fate of menthofuran in rats. Novel oxidative pathways.
    K M Madyastha and C P Raj
    Drug Metabolism and Disposition March 1992, 20 (2) 295-301;
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    Pharmacokinetics of caffeine and its demethylated metabolites in lactating adult rabbits and neonatal offspring. Predictions of breast milk to serum concentration ratios.
    P J McNamara, D Burgio and S D Yoo
    Drug Metabolism and Disposition March 1992, 20 (2) 302-308;
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    Alpha-glucoside formation of xenobiotics by rat liver alpha-glucosidases.
    H Kamimura, H Ogata and H Takahara
    Drug Metabolism and Disposition March 1992, 20 (2) 309-315;
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    Involvement of the cytochrome P-450IID subfamily in minaprine 4-hydroxylation by human hepatic microsomes.
    F Marre, G Fabre, B Lacarelle, M Bourrie, J Catalin, Y Berger, R Rahmani and J P Cano
    Drug Metabolism and Disposition March 1992, 20 (2) 316-321;
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    Metabolic inversion of (R)-ibuprofen. Epimerization and hydrolysis of ibuprofenyl-coenzyme A.
    T S Tracy and S D Hall
    Drug Metabolism and Disposition March 1992, 20 (2) 322-327;
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    Glucuronidation of zileuton (A-64077) by human hepatic microsomes.
    D J Sweeny, J Bouska, J Machinist, R Bell, G Carter, S Cepa and H N Nellans
    Drug Metabolism and Disposition March 1992, 20 (2) 328-329;
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    New evidence of sparteine metabolites in humans.
    J Pospísil, V Patzelová and B Máca
    Drug Metabolism and Disposition March 1992, 20 (2) 330-332;
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    Stereoselective sulfate conjugation of 4-hydroxypropranolol and terbutaline by the human liver phenolsulfotransferases.
    T Walle and U K Walle
    Drug Metabolism and Disposition March 1992, 20 (2) 333-336;
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    Carboxyphosphamide: NMR studies of its stability and cell membrane permeability.
    S M Ludeman, C K Ho, J H Boal, E M Sweet and Y H Chang
    Drug Metabolism and Disposition March 1992, 20 (2) 337-338;
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    Interactions of a primary N-hydroxy arylamine with rat hepatic aryl sulfotransferase IV.
    M W Duffel, R B Modi and R S King
    Drug Metabolism and Disposition March 1992, 20 (2) 339-341;
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In this issue

Drug Metabolism and Disposition
Vol. 20, Issue 2
1 Mar 1992
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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