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Drug Metabolism & Disposition

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  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
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Index by author

March 01, 1992; Volume 20,Issue 2
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Andersson, K E

    1. You have access
      Disposition and pharmacokinetics of [14C]finasteride after oral administration in humans.
      J R Carlin, P Höglund, L O Eriksson, P Christofalo, S L Gregoire, A M Taylor and K E Andersson
      Drug Metabolism and Disposition March 1992, 20 (2) 148-155;

B

  1. Bell, R

    1. You have access
      Glucuronidation of zileuton (A-64077) by human hepatic microsomes.
      D J Sweeny, J Bouska, J Machinist, R Bell, G Carter, S Cepa and H N Nellans
      Drug Metabolism and Disposition March 1992, 20 (2) 328-329;
  2. Berger, Y

    1. You have access
      Involvement of the cytochrome P-450IID subfamily in minaprine 4-hydroxylation by human hepatic microsomes.
      F Marre, G Fabre, B Lacarelle, M Bourrie, J Catalin, Y Berger, R Rahmani and J P Cano
      Drug Metabolism and Disposition March 1992, 20 (2) 316-321;
  3. Boal, J H

    1. You have access
      Carboxyphosphamide: NMR studies of its stability and cell membrane permeability.
      S M Ludeman, C K Ho, J H Boal, E M Sweet and Y H Chang
      Drug Metabolism and Disposition March 1992, 20 (2) 337-338;
  4. Bock, K W

    1. You have access
      Influence of P-4502E1 induction on benzene metabolism in rat hepatocytes and on biliary metabolite excretion.
      D Schrenk, M Ingelman-Sundberg and K W Bock
      Drug Metabolism and Disposition March 1992, 20 (2) 137-141;
  5. Bornheim, L M

    1. You have access
      Human hepatic microsomal metabolism of delta 1-tetrahydrocannabinol.
      L M Bornheim, J M Lasker and J L Raucy
      Drug Metabolism and Disposition March 1992, 20 (2) 241-246;
  6. Bourrie, M

    1. You have access
      Involvement of the cytochrome P-450IID subfamily in minaprine 4-hydroxylation by human hepatic microsomes.
      F Marre, G Fabre, B Lacarelle, M Bourrie, J Catalin, Y Berger, R Rahmani and J P Cano
      Drug Metabolism and Disposition March 1992, 20 (2) 316-321;
  7. Bouska, J

    1. You have access
      Glucuronidation of zileuton (A-64077) by human hepatic microsomes.
      D J Sweeny, J Bouska, J Machinist, R Bell, G Carter, S Cepa and H N Nellans
      Drug Metabolism and Disposition March 1992, 20 (2) 328-329;
  8. Bundgaard, H

    1. You have access
      Glucuronidation of the dopamine D-1 receptor antagonists NNC 0756 and NNC 0772 in liver microsomes.
      K T Hansen, K F Thomsen and H Bundgaard
      Drug Metabolism and Disposition March 1992, 20 (2) 172-178;
  9. Burgio, D

    1. You have access
      Pharmacokinetics of caffeine and its demethylated metabolites in lactating adult rabbits and neonatal offspring. Predictions of breast milk to serum concentration ratios.
      P J McNamara, D Burgio and S D Yoo
      Drug Metabolism and Disposition March 1992, 20 (2) 302-308;
  10. Byrd, G D

    1. You have access
      Evidence for urinary excretion of glucuronide conjugates of nicotine, cotinine, and trans-3'-hydroxycotinine in smokers.
      G D Byrd, K M Chang, J M Greene and J D deBethizy
      Drug Metabolism and Disposition March 1992, 20 (2) 192-197;

C

  1. Cano, J P

    1. You have access
      Involvement of the cytochrome P-450IID subfamily in minaprine 4-hydroxylation by human hepatic microsomes.
      F Marre, G Fabre, B Lacarelle, M Bourrie, J Catalin, Y Berger, R Rahmani and J P Cano
      Drug Metabolism and Disposition March 1992, 20 (2) 316-321;
  2. Carlin, J R

    1. You have access
      Disposition and pharmacokinetics of [14C]finasteride after oral administration in humans.
      J R Carlin, P Höglund, L O Eriksson, P Christofalo, S L Gregoire, A M Taylor and K E Andersson
      Drug Metabolism and Disposition March 1992, 20 (2) 148-155;
  3. Carter, G

    1. You have access
      Glucuronidation of zileuton (A-64077) by human hepatic microsomes.
      D J Sweeny, J Bouska, J Machinist, R Bell, G Carter, S Cepa and H N Nellans
      Drug Metabolism and Disposition March 1992, 20 (2) 328-329;
  4. Catalin, J

    1. You have access
      Involvement of the cytochrome P-450IID subfamily in minaprine 4-hydroxylation by human hepatic microsomes.
      F Marre, G Fabre, B Lacarelle, M Bourrie, J Catalin, Y Berger, R Rahmani and J P Cano
      Drug Metabolism and Disposition March 1992, 20 (2) 316-321;
  5. Cepa, S

    1. You have access
      Glucuronidation of zileuton (A-64077) by human hepatic microsomes.
      D J Sweeny, J Bouska, J Machinist, R Bell, G Carter, S Cepa and H N Nellans
      Drug Metabolism and Disposition March 1992, 20 (2) 328-329;
  6. Chadwick, M

    1. You have access
      Comparative metabolism and disposition of furfural and furfuryl alcohol in rats.
      A A Nomeir, D M Silveira, M F McComish and M Chadwick
      Drug Metabolism and Disposition March 1992, 20 (2) 198-204;
  7. Chakravarty, P K

    1. You have access
      The metabolism of DuP 753, a nonpeptide angiotensin II receptor antagonist, by rat, monkey, and human liver slices.
      R A Stearns, R R Miller, G A Doss, P K Chakravarty, A Rosegay, G J Gatto and S H Chiu
      Drug Metabolism and Disposition March 1992, 20 (2) 281-287;
  8. Chang, K M

    1. You have access
      Evidence for urinary excretion of glucuronide conjugates of nicotine, cotinine, and trans-3'-hydroxycotinine in smokers.
      G D Byrd, K M Chang, J M Greene and J D deBethizy
      Drug Metabolism and Disposition March 1992, 20 (2) 192-197;
  9. Chang, Y H

    1. You have access
      Carboxyphosphamide: NMR studies of its stability and cell membrane permeability.
      S M Ludeman, C K Ho, J H Boal, E M Sweet and Y H Chang
      Drug Metabolism and Disposition March 1992, 20 (2) 337-338;
  10. Chien, D S

    1. You have access
      Systemic pharmacokinetics of acitretin, etretinate, isotretinoin, and acetylenic retinoids in guinea pigs and obese rats.
      D S Chien, R B Sandri and D S Tang-Liu
      Drug Metabolism and Disposition March 1992, 20 (2) 211-217;
  11. Chiu, S H

    1. You have access
      The metabolism of DuP 753, a nonpeptide angiotensin II receptor antagonist, by rat, monkey, and human liver slices.
      R A Stearns, R R Miller, G A Doss, P K Chakravarty, A Rosegay, G J Gatto and S H Chiu
      Drug Metabolism and Disposition March 1992, 20 (2) 281-287;
  12. Chow, H H

    1. You have access
      The influence of vitamin K3 treatment on the pharmacokinetics and metabolism of (+)-propranolol in the rat.
      H H Chow and D Lalka
      Drug Metabolism and Disposition March 1992, 20 (2) 288-294;
  13. Christians, U

    1. You have access
      Isolation of two immunosuppressive metabolites after in vitro metabolism of rapamycin.
      U Christians, M Sattler, H M Schiebel, C Kruse, H H Radeke, A Linck and K F Sewing
      Drug Metabolism and Disposition March 1992, 20 (2) 186-191;
  14. Christofalo, P

    1. You have access
      Disposition and pharmacokinetics of [14C]finasteride after oral administration in humans.
      J R Carlin, P Höglund, L O Eriksson, P Christofalo, S L Gregoire, A M Taylor and K E Andersson
      Drug Metabolism and Disposition March 1992, 20 (2) 148-155;

D

  1. Damani, L A

    1. You have access
      Urinary metabolic profiles in human and rat of 1,2-dimethyl- and 1,2-diethyl-substituted 3-hydroxypyridin-4-ones.
      S Singh, R O Epemolu, P S Dobbin, G S Tilbrook, B L Ellis, L A Damani and R C Hider
      Drug Metabolism and Disposition March 1992, 20 (2) 256-261;
  2. deBethizy, J D

    1. You have access
      Evidence for urinary excretion of glucuronide conjugates of nicotine, cotinine, and trans-3'-hydroxycotinine in smokers.
      G D Byrd, K M Chang, J M Greene and J D deBethizy
      Drug Metabolism and Disposition March 1992, 20 (2) 192-197;
  3. Deleon, J H

    1. You have access
      Methacrylonitrile: in vivo metabolism to cyanide in rats, mice, and gerbils.
      M Y Farooqui, R G Diaz and J H Deleon
      Drug Metabolism and Disposition March 1992, 20 (2) 156-160;
  4. Deloria, L B

    1. You have access
      Identification of the antibiotic hops component, colupulone, as an inducer of hepatic cytochrome P-4503A in the mouse.
      G J Mannering, J A Shoeman and L B Deloria
      Drug Metabolism and Disposition March 1992, 20 (2) 142-147;
  5. Diaz, R G

    1. You have access
      Methacrylonitrile: in vivo metabolism to cyanide in rats, mice, and gerbils.
      M Y Farooqui, R G Diaz and J H Deleon
      Drug Metabolism and Disposition March 1992, 20 (2) 156-160;
  6. Dobbin, P S

    1. You have access
      Urinary metabolic profiles in human and rat of 1,2-dimethyl- and 1,2-diethyl-substituted 3-hydroxypyridin-4-ones.
      S Singh, R O Epemolu, P S Dobbin, G S Tilbrook, B L Ellis, L A Damani and R C Hider
      Drug Metabolism and Disposition March 1992, 20 (2) 256-261;
  7. Doss, G A

    1. You have access
      The metabolism of DuP 753, a nonpeptide angiotensin II receptor antagonist, by rat, monkey, and human liver slices.
      R A Stearns, R R Miller, G A Doss, P K Chakravarty, A Rosegay, G J Gatto and S H Chiu
      Drug Metabolism and Disposition March 1992, 20 (2) 281-287;
  8. Dueker, S R

    1. You have access
      Guinea pig and rat hepatic microsomal metabolism of monocrotaline.
      S R Dueker, M W Lamé, D Morin, D W Wilson and H J Segall
      Drug Metabolism and Disposition March 1992, 20 (2) 275-280;
  9. Duffel, M W

    1. You have access
      Interactions of a primary N-hydroxy arylamine with rat hepatic aryl sulfotransferase IV.
      M W Duffel, R B Modi and R S King
      Drug Metabolism and Disposition March 1992, 20 (2) 339-341;

E

  1. Ellis, B L

    1. You have access
      Urinary metabolic profiles in human and rat of 1,2-dimethyl- and 1,2-diethyl-substituted 3-hydroxypyridin-4-ones.
      S Singh, R O Epemolu, P S Dobbin, G S Tilbrook, B L Ellis, L A Damani and R C Hider
      Drug Metabolism and Disposition March 1992, 20 (2) 256-261;
  2. Epemolu, R O

    1. You have access
      Urinary metabolic profiles in human and rat of 1,2-dimethyl- and 1,2-diethyl-substituted 3-hydroxypyridin-4-ones.
      S Singh, R O Epemolu, P S Dobbin, G S Tilbrook, B L Ellis, L A Damani and R C Hider
      Drug Metabolism and Disposition March 1992, 20 (2) 256-261;
  3. Eriksson, L O

    1. You have access
      Disposition and pharmacokinetics of [14C]finasteride after oral administration in humans.
      J R Carlin, P Höglund, L O Eriksson, P Christofalo, S L Gregoire, A M Taylor and K E Andersson
      Drug Metabolism and Disposition March 1992, 20 (2) 148-155;

F

  1. Fabre, G

    1. You have access
      Involvement of the cytochrome P-450IID subfamily in minaprine 4-hydroxylation by human hepatic microsomes.
      F Marre, G Fabre, B Lacarelle, M Bourrie, J Catalin, Y Berger, R Rahmani and J P Cano
      Drug Metabolism and Disposition March 1992, 20 (2) 316-321;
  2. Farooqui, M Y

    1. You have access
      Methacrylonitrile: in vivo metabolism to cyanide in rats, mice, and gerbils.
      M Y Farooqui, R G Diaz and J H Deleon
      Drug Metabolism and Disposition March 1992, 20 (2) 156-160;
  3. Fekete, T

    1. You have access
      Availability of glycine and coenzyme A limits glycine conjugation in vivo.
      Z Gregus, T Fekete, F Varga and C D Klaassen
      Drug Metabolism and Disposition March 1992, 20 (2) 234-240;

G

  1. Gatto, G J

    1. You have access
      The metabolism of DuP 753, a nonpeptide angiotensin II receptor antagonist, by rat, monkey, and human liver slices.
      R A Stearns, R R Miller, G A Doss, P K Chakravarty, A Rosegay, G J Gatto and S H Chiu
      Drug Metabolism and Disposition March 1992, 20 (2) 281-287;
  2. Glauser, T A

    1. You have access
      Human hepatic microsomal thiol methyltransferase. Assay conditions, biochemical properties, and correlation studies.
      T A Glauser, A L Kerremans and R M Weinshilboum
      Drug Metabolism and Disposition March 1992, 20 (2) 247-255;
  3. Greene, J M

    1. You have access
      Evidence for urinary excretion of glucuronide conjugates of nicotine, cotinine, and trans-3'-hydroxycotinine in smokers.
      G D Byrd, K M Chang, J M Greene and J D deBethizy
      Drug Metabolism and Disposition March 1992, 20 (2) 192-197;
  4. Gregoire, S L

    1. You have access
      Disposition and pharmacokinetics of [14C]finasteride after oral administration in humans.
      J R Carlin, P Höglund, L O Eriksson, P Christofalo, S L Gregoire, A M Taylor and K E Andersson
      Drug Metabolism and Disposition March 1992, 20 (2) 148-155;
  5. Gregus, Z

    1. You have access
      Availability of glycine and coenzyme A limits glycine conjugation in vivo.
      Z Gregus, T Fekete, F Varga and C D Klaassen
      Drug Metabolism and Disposition March 1992, 20 (2) 234-240;

H

  1. Hall, S D

    1. You have access
      Metabolic inversion of (R)-ibuprofen. Epimerization and hydrolysis of ibuprofenyl-coenzyme A.
      T S Tracy and S D Hall
      Drug Metabolism and Disposition March 1992, 20 (2) 322-327;
  2. Hansen, K T

    1. You have access
      Glucuronidation of the dopamine D-1 receptor antagonists NNC 0756 and NNC 0772 in liver microsomes.
      K T Hansen, K F Thomsen and H Bundgaard
      Drug Metabolism and Disposition March 1992, 20 (2) 172-178;
  3. Hermans, J J

    1. You have access
      Stereoselective acetonyl side chain reduction of warfarin and analogs. Partial characterization of two cytosolic carbonyl reductases.
      J J Hermans and H H Thijssen
      Drug Metabolism and Disposition March 1992, 20 (2) 268-274;
  4. Hider, R C

    1. You have access
      Urinary metabolic profiles in human and rat of 1,2-dimethyl- and 1,2-diethyl-substituted 3-hydroxypyridin-4-ones.
      S Singh, R O Epemolu, P S Dobbin, G S Tilbrook, B L Ellis, L A Damani and R C Hider
      Drug Metabolism and Disposition March 1992, 20 (2) 256-261;
  5. Hiraoka, K

    1. You have access
      Metabolism of sodium nifurstyrenate, a veterinary antimicrobial nitrofuran, in animals and fish.
      K Tatsumi, S Kitamura, M Kato and K Hiraoka
      Drug Metabolism and Disposition March 1992, 20 (2) 226-233;
  6. Ho, C K

    1. You have access
      Carboxyphosphamide: NMR studies of its stability and cell membrane permeability.
      S M Ludeman, C K Ho, J H Boal, E M Sweet and Y H Chang
      Drug Metabolism and Disposition March 1992, 20 (2) 337-338;
  7. Hofstra, A H

    1. You have access
      Metabolism of isoniazid by activated leukocytes. Possible role in drug-induced lupus.
      A H Hofstra, S M Li-Muller and J P Uetrecht
      Drug Metabolism and Disposition March 1992, 20 (2) 205-210;
  8. Höglund, P

    1. You have access
      Disposition and pharmacokinetics of [14C]finasteride after oral administration in humans.
      J R Carlin, P Höglund, L O Eriksson, P Christofalo, S L Gregoire, A M Taylor and K E Andersson
      Drug Metabolism and Disposition March 1992, 20 (2) 148-155;

I

  1. Ingelman-Sundberg, M

    1. You have access
      Influence of P-4502E1 induction on benzene metabolism in rat hepatocytes and on biliary metabolite excretion.
      D Schrenk, M Ingelman-Sundberg and K W Bock
      Drug Metabolism and Disposition March 1992, 20 (2) 137-141;

J

  1. Juchau, M R

    1. You have access
      Correlations between conceptal concentrations of all-trans-retinoic acid and dysmorphogenesis after microinjections of all-trans-retinoic acid, 13-cis-retinoic acid, all-trans-retinoyl-beta-glucuronide, or retinol in cultured whole rat embryos.
      J C Kraft and M R Juchau
      Drug Metabolism and Disposition March 1992, 20 (2) 218-225;

K

  1. Kamimura, H

    1. You have access
      Alpha-glucoside formation of xenobiotics by rat liver alpha-glucosidases.
      H Kamimura, H Ogata and H Takahara
      Drug Metabolism and Disposition March 1992, 20 (2) 309-315;
  2. Karlsson, K E

    1. You have access
      A metabolic route of omeprazole involving conjugation with glutathione identified in the rat.
      L Weidolf, K E Karlsson and I Nilsson
      Drug Metabolism and Disposition March 1992, 20 (2) 262-267;
  3. Kato, M

    1. You have access
      Metabolism of sodium nifurstyrenate, a veterinary antimicrobial nitrofuran, in animals and fish.
      K Tatsumi, S Kitamura, M Kato and K Hiraoka
      Drug Metabolism and Disposition March 1992, 20 (2) 226-233;
  4. Kato, Y

    1. You have access
      Identification of biliary metabolites of m-dichlorobenzene in rats.
      R Kimura, N Ohishi, Y Kato, S Yamada and M Sato
      Drug Metabolism and Disposition March 1992, 20 (2) 161-171;
  5. Kawahara, S

    1. You have access
      Stereoselective renal tubular secretion of a new uricosuric diuretic, 6,7-dichloro-5-(N,N-dimethylsulfamoyl)-2,3-dihydro-2-benzofurancarboxyl ic acid (S-8666), in cynomolgus monkeys.
      M Nakano and S Kawahara
      Drug Metabolism and Disposition March 1992, 20 (2) 179-185;
  6. Kerremans, A L

    1. You have access
      Human hepatic microsomal thiol methyltransferase. Assay conditions, biochemical properties, and correlation studies.
      T A Glauser, A L Kerremans and R M Weinshilboum
      Drug Metabolism and Disposition March 1992, 20 (2) 247-255;
  7. Kimura, R

    1. You have access
      Identification of biliary metabolites of m-dichlorobenzene in rats.
      R Kimura, N Ohishi, Y Kato, S Yamada and M Sato
      Drug Metabolism and Disposition March 1992, 20 (2) 161-171;
  8. King, R S

    1. You have access
      Interactions of a primary N-hydroxy arylamine with rat hepatic aryl sulfotransferase IV.
      M W Duffel, R B Modi and R S King
      Drug Metabolism and Disposition March 1992, 20 (2) 339-341;
  9. Kitamura, S

    1. You have access
      Metabolism of sodium nifurstyrenate, a veterinary antimicrobial nitrofuran, in animals and fish.
      K Tatsumi, S Kitamura, M Kato and K Hiraoka
      Drug Metabolism and Disposition March 1992, 20 (2) 226-233;
  10. Klaassen, C D

    1. You have access
      Availability of glycine and coenzyme A limits glycine conjugation in vivo.
      Z Gregus, T Fekete, F Varga and C D Klaassen
      Drug Metabolism and Disposition March 1992, 20 (2) 234-240;
  11. Kraft, J C

    1. You have access
      Correlations between conceptal concentrations of all-trans-retinoic acid and dysmorphogenesis after microinjections of all-trans-retinoic acid, 13-cis-retinoic acid, all-trans-retinoyl-beta-glucuronide, or retinol in cultured whole rat embryos.
      J C Kraft and M R Juchau
      Drug Metabolism and Disposition March 1992, 20 (2) 218-225;
  12. Kruse, C

    1. You have access
      Isolation of two immunosuppressive metabolites after in vitro metabolism of rapamycin.
      U Christians, M Sattler, H M Schiebel, C Kruse, H H Radeke, A Linck and K F Sewing
      Drug Metabolism and Disposition March 1992, 20 (2) 186-191;

L

  1. Lacarelle, B

    1. You have access
      Involvement of the cytochrome P-450IID subfamily in minaprine 4-hydroxylation by human hepatic microsomes.
      F Marre, G Fabre, B Lacarelle, M Bourrie, J Catalin, Y Berger, R Rahmani and J P Cano
      Drug Metabolism and Disposition March 1992, 20 (2) 316-321;
  2. Lalka, D

    1. You have access
      The influence of vitamin K3 treatment on the pharmacokinetics and metabolism of (+)-propranolol in the rat.
      H H Chow and D Lalka
      Drug Metabolism and Disposition March 1992, 20 (2) 288-294;
  3. Lamé, M W

    1. You have access
      Guinea pig and rat hepatic microsomal metabolism of monocrotaline.
      S R Dueker, M W Lamé, D Morin, D W Wilson and H J Segall
      Drug Metabolism and Disposition March 1992, 20 (2) 275-280;
  4. Lasker, J M

    1. You have access
      Human hepatic microsomal metabolism of delta 1-tetrahydrocannabinol.
      L M Bornheim, J M Lasker and J L Raucy
      Drug Metabolism and Disposition March 1992, 20 (2) 241-246;
  5. Li-Muller, S M

    1. You have access
      Metabolism of isoniazid by activated leukocytes. Possible role in drug-induced lupus.
      A H Hofstra, S M Li-Muller and J P Uetrecht
      Drug Metabolism and Disposition March 1992, 20 (2) 205-210;
  6. Linck, A

    1. You have access
      Isolation of two immunosuppressive metabolites after in vitro metabolism of rapamycin.
      U Christians, M Sattler, H M Schiebel, C Kruse, H H Radeke, A Linck and K F Sewing
      Drug Metabolism and Disposition March 1992, 20 (2) 186-191;
  7. Ludeman, S M

    1. You have access
      Carboxyphosphamide: NMR studies of its stability and cell membrane permeability.
      S M Ludeman, C K Ho, J H Boal, E M Sweet and Y H Chang
      Drug Metabolism and Disposition March 1992, 20 (2) 337-338;

M

  1. Máca, B

    1. You have access
      New evidence of sparteine metabolites in humans.
      J Pospísil, V Patzelová and B Máca
      Drug Metabolism and Disposition March 1992, 20 (2) 330-332;
  2. Machinist, J

    1. You have access
      Glucuronidation of zileuton (A-64077) by human hepatic microsomes.
      D J Sweeny, J Bouska, J Machinist, R Bell, G Carter, S Cepa and H N Nellans
      Drug Metabolism and Disposition March 1992, 20 (2) 328-329;
  3. Madyastha, K M

    1. You have access
      Metabolic fate of menthofuran in rats. Novel oxidative pathways.
      K M Madyastha and C P Raj
      Drug Metabolism and Disposition March 1992, 20 (2) 295-301;
  4. Mannering, G J

    1. You have access
      Identification of the antibiotic hops component, colupulone, as an inducer of hepatic cytochrome P-4503A in the mouse.
      G J Mannering, J A Shoeman and L B Deloria
      Drug Metabolism and Disposition March 1992, 20 (2) 142-147;
  5. Marre, F

    1. You have access
      Involvement of the cytochrome P-450IID subfamily in minaprine 4-hydroxylation by human hepatic microsomes.
      F Marre, G Fabre, B Lacarelle, M Bourrie, J Catalin, Y Berger, R Rahmani and J P Cano
      Drug Metabolism and Disposition March 1992, 20 (2) 316-321;
  6. McComish, M F

    1. You have access
      Comparative metabolism and disposition of furfural and furfuryl alcohol in rats.
      A A Nomeir, D M Silveira, M F McComish and M Chadwick
      Drug Metabolism and Disposition March 1992, 20 (2) 198-204;
  7. McNamara, P J

    1. You have access
      Pharmacokinetics of caffeine and its demethylated metabolites in lactating adult rabbits and neonatal offspring. Predictions of breast milk to serum concentration ratios.
      P J McNamara, D Burgio and S D Yoo
      Drug Metabolism and Disposition March 1992, 20 (2) 302-308;
  8. Miller, R R

    1. You have access
      The metabolism of DuP 753, a nonpeptide angiotensin II receptor antagonist, by rat, monkey, and human liver slices.
      R A Stearns, R R Miller, G A Doss, P K Chakravarty, A Rosegay, G J Gatto and S H Chiu
      Drug Metabolism and Disposition March 1992, 20 (2) 281-287;
  9. Modi, R B

    1. You have access
      Interactions of a primary N-hydroxy arylamine with rat hepatic aryl sulfotransferase IV.
      M W Duffel, R B Modi and R S King
      Drug Metabolism and Disposition March 1992, 20 (2) 339-341;
  10. Morin, D

    1. You have access
      Guinea pig and rat hepatic microsomal metabolism of monocrotaline.
      S R Dueker, M W Lamé, D Morin, D W Wilson and H J Segall
      Drug Metabolism and Disposition March 1992, 20 (2) 275-280;

N

  1. Nakano, M

    1. You have access
      Stereoselective renal tubular secretion of a new uricosuric diuretic, 6,7-dichloro-5-(N,N-dimethylsulfamoyl)-2,3-dihydro-2-benzofurancarboxyl ic acid (S-8666), in cynomolgus monkeys.
      M Nakano and S Kawahara
      Drug Metabolism and Disposition March 1992, 20 (2) 179-185;
  2. Nellans, H N

    1. You have access
      Glucuronidation of zileuton (A-64077) by human hepatic microsomes.
      D J Sweeny, J Bouska, J Machinist, R Bell, G Carter, S Cepa and H N Nellans
      Drug Metabolism and Disposition March 1992, 20 (2) 328-329;
  3. Nilsson, I

    1. You have access
      A metabolic route of omeprazole involving conjugation with glutathione identified in the rat.
      L Weidolf, K E Karlsson and I Nilsson
      Drug Metabolism and Disposition March 1992, 20 (2) 262-267;
  4. Nomeir, A A

    1. You have access
      Comparative metabolism and disposition of furfural and furfuryl alcohol in rats.
      A A Nomeir, D M Silveira, M F McComish and M Chadwick
      Drug Metabolism and Disposition March 1992, 20 (2) 198-204;

O

  1. Ogata, H

    1. You have access
      Alpha-glucoside formation of xenobiotics by rat liver alpha-glucosidases.
      H Kamimura, H Ogata and H Takahara
      Drug Metabolism and Disposition March 1992, 20 (2) 309-315;
  2. Ohishi, N

    1. You have access
      Identification of biliary metabolites of m-dichlorobenzene in rats.
      R Kimura, N Ohishi, Y Kato, S Yamada and M Sato
      Drug Metabolism and Disposition March 1992, 20 (2) 161-171;

P

  1. Patzelová, V

    1. You have access
      New evidence of sparteine metabolites in humans.
      J Pospísil, V Patzelová and B Máca
      Drug Metabolism and Disposition March 1992, 20 (2) 330-332;
  2. Pospísil, J

    1. You have access
      New evidence of sparteine metabolites in humans.
      J Pospísil, V Patzelová and B Máca
      Drug Metabolism and Disposition March 1992, 20 (2) 330-332;

R

  1. Radeke, H H

    1. You have access
      Isolation of two immunosuppressive metabolites after in vitro metabolism of rapamycin.
      U Christians, M Sattler, H M Schiebel, C Kruse, H H Radeke, A Linck and K F Sewing
      Drug Metabolism and Disposition March 1992, 20 (2) 186-191;
  2. Rahmani, R

    1. You have access
      Involvement of the cytochrome P-450IID subfamily in minaprine 4-hydroxylation by human hepatic microsomes.
      F Marre, G Fabre, B Lacarelle, M Bourrie, J Catalin, Y Berger, R Rahmani and J P Cano
      Drug Metabolism and Disposition March 1992, 20 (2) 316-321;
  3. Raj, C P

    1. You have access
      Metabolic fate of menthofuran in rats. Novel oxidative pathways.
      K M Madyastha and C P Raj
      Drug Metabolism and Disposition March 1992, 20 (2) 295-301;
  4. Raucy, J L

    1. You have access
      Human hepatic microsomal metabolism of delta 1-tetrahydrocannabinol.
      L M Bornheim, J M Lasker and J L Raucy
      Drug Metabolism and Disposition March 1992, 20 (2) 241-246;
  5. Rosegay, A

    1. You have access
      The metabolism of DuP 753, a nonpeptide angiotensin II receptor antagonist, by rat, monkey, and human liver slices.
      R A Stearns, R R Miller, G A Doss, P K Chakravarty, A Rosegay, G J Gatto and S H Chiu
      Drug Metabolism and Disposition March 1992, 20 (2) 281-287;

S

  1. Sandri, R B

    1. You have access
      Systemic pharmacokinetics of acitretin, etretinate, isotretinoin, and acetylenic retinoids in guinea pigs and obese rats.
      D S Chien, R B Sandri and D S Tang-Liu
      Drug Metabolism and Disposition March 1992, 20 (2) 211-217;
  2. Sato, M

    1. You have access
      Identification of biliary metabolites of m-dichlorobenzene in rats.
      R Kimura, N Ohishi, Y Kato, S Yamada and M Sato
      Drug Metabolism and Disposition March 1992, 20 (2) 161-171;
  3. Sattler, M

    1. You have access
      Isolation of two immunosuppressive metabolites after in vitro metabolism of rapamycin.
      U Christians, M Sattler, H M Schiebel, C Kruse, H H Radeke, A Linck and K F Sewing
      Drug Metabolism and Disposition March 1992, 20 (2) 186-191;
  4. Schiebel, H M

    1. You have access
      Isolation of two immunosuppressive metabolites after in vitro metabolism of rapamycin.
      U Christians, M Sattler, H M Schiebel, C Kruse, H H Radeke, A Linck and K F Sewing
      Drug Metabolism and Disposition March 1992, 20 (2) 186-191;
  5. Schrenk, D

    1. You have access
      Influence of P-4502E1 induction on benzene metabolism in rat hepatocytes and on biliary metabolite excretion.
      D Schrenk, M Ingelman-Sundberg and K W Bock
      Drug Metabolism and Disposition March 1992, 20 (2) 137-141;
  6. Segall, H J

    1. You have access
      Guinea pig and rat hepatic microsomal metabolism of monocrotaline.
      S R Dueker, M W Lamé, D Morin, D W Wilson and H J Segall
      Drug Metabolism and Disposition March 1992, 20 (2) 275-280;
  7. Sewing, K F

    1. You have access
      Isolation of two immunosuppressive metabolites after in vitro metabolism of rapamycin.
      U Christians, M Sattler, H M Schiebel, C Kruse, H H Radeke, A Linck and K F Sewing
      Drug Metabolism and Disposition March 1992, 20 (2) 186-191;
  8. Shoeman, J A

    1. You have access
      Identification of the antibiotic hops component, colupulone, as an inducer of hepatic cytochrome P-4503A in the mouse.
      G J Mannering, J A Shoeman and L B Deloria
      Drug Metabolism and Disposition March 1992, 20 (2) 142-147;
  9. Silveira, D M

    1. You have access
      Comparative metabolism and disposition of furfural and furfuryl alcohol in rats.
      A A Nomeir, D M Silveira, M F McComish and M Chadwick
      Drug Metabolism and Disposition March 1992, 20 (2) 198-204;
  10. Singh, S

    1. You have access
      Urinary metabolic profiles in human and rat of 1,2-dimethyl- and 1,2-diethyl-substituted 3-hydroxypyridin-4-ones.
      S Singh, R O Epemolu, P S Dobbin, G S Tilbrook, B L Ellis, L A Damani and R C Hider
      Drug Metabolism and Disposition March 1992, 20 (2) 256-261;
  11. Stearns, R A

    1. You have access
      The metabolism of DuP 753, a nonpeptide angiotensin II receptor antagonist, by rat, monkey, and human liver slices.
      R A Stearns, R R Miller, G A Doss, P K Chakravarty, A Rosegay, G J Gatto and S H Chiu
      Drug Metabolism and Disposition March 1992, 20 (2) 281-287;
  12. Sweeny, D J

    1. You have access
      Glucuronidation of zileuton (A-64077) by human hepatic microsomes.
      D J Sweeny, J Bouska, J Machinist, R Bell, G Carter, S Cepa and H N Nellans
      Drug Metabolism and Disposition March 1992, 20 (2) 328-329;
  13. Sweet, E M

    1. You have access
      Carboxyphosphamide: NMR studies of its stability and cell membrane permeability.
      S M Ludeman, C K Ho, J H Boal, E M Sweet and Y H Chang
      Drug Metabolism and Disposition March 1992, 20 (2) 337-338;

T

  1. Takahara, H

    1. You have access
      Alpha-glucoside formation of xenobiotics by rat liver alpha-glucosidases.
      H Kamimura, H Ogata and H Takahara
      Drug Metabolism and Disposition March 1992, 20 (2) 309-315;
  2. Tang-Liu, D S

    1. You have access
      Systemic pharmacokinetics of acitretin, etretinate, isotretinoin, and acetylenic retinoids in guinea pigs and obese rats.
      D S Chien, R B Sandri and D S Tang-Liu
      Drug Metabolism and Disposition March 1992, 20 (2) 211-217;
  3. Tatsumi, K

    1. You have access
      Metabolism of sodium nifurstyrenate, a veterinary antimicrobial nitrofuran, in animals and fish.
      K Tatsumi, S Kitamura, M Kato and K Hiraoka
      Drug Metabolism and Disposition March 1992, 20 (2) 226-233;
  4. Taylor, A M

    1. You have access
      Disposition and pharmacokinetics of [14C]finasteride after oral administration in humans.
      J R Carlin, P Höglund, L O Eriksson, P Christofalo, S L Gregoire, A M Taylor and K E Andersson
      Drug Metabolism and Disposition March 1992, 20 (2) 148-155;
  5. Thijssen, H H

    1. You have access
      Stereoselective acetonyl side chain reduction of warfarin and analogs. Partial characterization of two cytosolic carbonyl reductases.
      J J Hermans and H H Thijssen
      Drug Metabolism and Disposition March 1992, 20 (2) 268-274;
  6. Thomsen, K F

    1. You have access
      Glucuronidation of the dopamine D-1 receptor antagonists NNC 0756 and NNC 0772 in liver microsomes.
      K T Hansen, K F Thomsen and H Bundgaard
      Drug Metabolism and Disposition March 1992, 20 (2) 172-178;
  7. Tilbrook, G S

    1. You have access
      Urinary metabolic profiles in human and rat of 1,2-dimethyl- and 1,2-diethyl-substituted 3-hydroxypyridin-4-ones.
      S Singh, R O Epemolu, P S Dobbin, G S Tilbrook, B L Ellis, L A Damani and R C Hider
      Drug Metabolism and Disposition March 1992, 20 (2) 256-261;
  8. Tracy, T S

    1. You have access
      Metabolic inversion of (R)-ibuprofen. Epimerization and hydrolysis of ibuprofenyl-coenzyme A.
      T S Tracy and S D Hall
      Drug Metabolism and Disposition March 1992, 20 (2) 322-327;

U

  1. Uetrecht, J P

    1. You have access
      Metabolism of isoniazid by activated leukocytes. Possible role in drug-induced lupus.
      A H Hofstra, S M Li-Muller and J P Uetrecht
      Drug Metabolism and Disposition March 1992, 20 (2) 205-210;

V

  1. Varga, F

    1. You have access
      Availability of glycine and coenzyme A limits glycine conjugation in vivo.
      Z Gregus, T Fekete, F Varga and C D Klaassen
      Drug Metabolism and Disposition March 1992, 20 (2) 234-240;

W

  1. Walle, T

    1. You have access
      Stereoselective sulfate conjugation of 4-hydroxypropranolol and terbutaline by the human liver phenolsulfotransferases.
      T Walle and U K Walle
      Drug Metabolism and Disposition March 1992, 20 (2) 333-336;
  2. Walle, U K

    1. You have access
      Stereoselective sulfate conjugation of 4-hydroxypropranolol and terbutaline by the human liver phenolsulfotransferases.
      T Walle and U K Walle
      Drug Metabolism and Disposition March 1992, 20 (2) 333-336;
  3. Weidolf, L

    1. You have access
      A metabolic route of omeprazole involving conjugation with glutathione identified in the rat.
      L Weidolf, K E Karlsson and I Nilsson
      Drug Metabolism and Disposition March 1992, 20 (2) 262-267;
  4. Weinshilboum, R M

    1. You have access
      Human hepatic microsomal thiol methyltransferase. Assay conditions, biochemical properties, and correlation studies.
      T A Glauser, A L Kerremans and R M Weinshilboum
      Drug Metabolism and Disposition March 1992, 20 (2) 247-255;
  5. Wilson, D W

    1. You have access
      Guinea pig and rat hepatic microsomal metabolism of monocrotaline.
      S R Dueker, M W Lamé, D Morin, D W Wilson and H J Segall
      Drug Metabolism and Disposition March 1992, 20 (2) 275-280;

Y

  1. Yamada, S

    1. You have access
      Identification of biliary metabolites of m-dichlorobenzene in rats.
      R Kimura, N Ohishi, Y Kato, S Yamada and M Sato
      Drug Metabolism and Disposition March 1992, 20 (2) 161-171;
  2. Yoo, S D

    1. You have access
      Pharmacokinetics of caffeine and its demethylated metabolites in lactating adult rabbits and neonatal offspring. Predictions of breast milk to serum concentration ratios.
      P J McNamara, D Burgio and S D Yoo
      Drug Metabolism and Disposition March 1992, 20 (2) 302-308;
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In this issue

Drug Metabolism and Disposition
Vol. 20, Issue 2
1 Mar 1992
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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