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Table of Contents

May 01, 1992; Volume 20,Issue 3

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Caffeine demethylase activity in human and Dark Agouti rat liver microsomes. Comparison with aminopyrine N-demethylase activity.
J A Agúndez, A Luengo and J Benítez

Drug Metabolism and Disposition May 1992, 20 (3) 343-349;
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Stereoselective disposition of S-8666, a novel uricosuric antihypertensive diuretic, and its N-monodemethylated metabolite in a perfused rat liver preparation. Effect of protein binding on the kinetics of S-8666.
K Higaki and M Nakano

Drug Metabolism and Disposition May 1992, 20 (3) 350-355;
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Diphenyl ether cleavage of 3-phenoxybenzoic acid by chicken kidney microsomal preparations.
M H Akhtar and S Mahadevan

Drug Metabolism and Disposition May 1992, 20 (3) 356-359;
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Differential expression of basal and hydrocarbon-induced cytochrome P-450 monooxygenase and quinone reductase activities in subpopulations of murine epidermal cells differing in their stages of differentiation.
J J Reiners, A R Cantu, G Thai and A Schöller

Drug Metabolism and Disposition May 1992, 20 (3) 360-366;
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Purification and characterization of a cytochrome P-450 isozyme catalyzing bunitrolol 4-hydroxylation in liver microsomes of male rats.
T Suzuki, S Narimatsu, S Fujita, Y Masubuchi, S Umeda, S Imaoka and Y Funae

Drug Metabolism and Disposition May 1992, 20 (3) 367-373;
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Homeostasis of sulfate and 3'-phosphoadenosine 5'-phosphosulfate in rats with deficient dietary intake of sulfur.
P Rozman, H J Kim, C Madhu, Z Gregus and C D Klaassen

Drug Metabolism and Disposition May 1992, 20 (3) 374-378;
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Inhibition of debrisoquin clearance in perfused rat livers and inhibition of dextromethorphan metabolism in human liver microsomes by 4-hydroxydebrisoquin or other metabolites of debrisoquin.
S Jaruratanasirikul, A D Cooper and T F Blaschke

Drug Metabolism and Disposition May 1992, 20 (3) 379-382;
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In vitro and in vivo biotransformations of the potent leukotriene D4 antagonist verlukast in the rat.
D Nicoll-Griffith, J Yergey, L Trimble, H Williams, R Rasori and R Zamboni

Drug Metabolism and Disposition May 1992, 20 (3) 383-389;
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Physiological disposition and metabolism of L-365,260, a potent antagonist of brain cholecystokinin receptor, in laboratory animals.
I W Chen, J M Dorley, H G Ramjit, S M Pitzenberger and J H Lin

Drug Metabolism and Disposition May 1992, 20 (3) 390-395;
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Pharmacokinetic evaluation of drug interactions with anti-human immunodeficiency virus drugs. V. Effect of soluble CD4 on 2',3'-dideoxycytidine kinetics in monkeys.
M Qian, A R Swagler, K L Fong, C S Crysler, M Mehta and J M Gallo

Drug Metabolism and Disposition May 1992, 20 (3) 396-401;
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Obesity as a risk factor in drug-induced organ injury. V. Toxicokinetics of gentamicin in the obese overfed rat.
D E Salazar, J J Schentag and G B Corcoran

Drug Metabolism and Disposition May 1992, 20 (3) 402-406;
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Differential effects of human recombinant interleukin-1 beta on cytochrome P-450-dependent activities in cultured fetal rat hepatocytes.
L Ferrari, P Kremers, A M Batt, J E Gielen and G Siest

Drug Metabolism and Disposition May 1992, 20 (3) 407-412;
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Sulfation of estrone and 17 beta-estradiol in human liver. Catalysis by thermostable phenol sulfotransferase and by dehydroepiandrosterone sulfotransferase.
J S Hernández, R W Watson, T C Wood and R M Weinshilboum

Drug Metabolism and Disposition May 1992, 20 (3) 413-422;
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Tissue concentrations of coenzyme Q10 in the rat following its oral and intraperitoneal administration.
S Reahal and J Wrigglesworth

Drug Metabolism and Disposition May 1992, 20 (3) 423-427;
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Physiological disposition of aerosolized MK-679 in rats.
D J Tocco, F A deluna, E Vadas and J H Lin

Drug Metabolism and Disposition May 1992, 20 (3) 428-431;
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Disposition kinetics of amphotericin B in rats. The influence of dose.
H H Chow, Y Cai and M Mayersohn

Drug Metabolism and Disposition May 1992, 20 (3) 432-435;
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Effect of dose on the percutaneous absorption of 2- and 4-chloronitrobenzene in rats.
A A Nomeir, P M Markham, A L Mongan, D M Silveira and M Chadwick

Drug Metabolism and Disposition May 1992, 20 (3) 436-439;
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Hydrolysis of the 2',3'-allylic epoxides of allylbenzene, estragole, eugenol, and safrole by both microsomal and cytosolic epoxide hydrolases.
G Luo, M K Qato and T M Guenthner

Drug Metabolism and Disposition May 1992, 20 (3) 440-445;
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Cytochrome P-450 in the brain. Potential evolutionary and therapeutic relevance of localization of drug-metabolizing enzymes.
M R Britto and P J Wedlund

Drug Metabolism and Disposition May 1992, 20 (3) 446-450;
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Isolation and characterization of carbinolamide and phenolic glucuronide conjugates of (+-)-N-methyl-N-(1-methyl-3,3-diphenylpropyl) formamide and N-formylmethamphetamine by FAB/MS, LC/MS/MS, and NMR.
A E Mutlib and F S Abbott

Drug Metabolism and Disposition May 1992, 20 (3) 451-460;
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Influence of dibutyryl-cAMP on ibuprofen-induced alterations of sulfate renal clearance in rats.
L J Benincosa and M E Morris

Drug Metabolism and Disposition May 1992, 20 (3) 461-464;
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Carbonyl (phenone) reductase in human liver: structure-activity relationship among substrates.
J M Wong, W A Mahon, W Kalow and T Inaba

Drug Metabolism and Disposition May 1992, 20 (3) 465-466;
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Distribution of 2,3,7,8-tetrachlorodibenzo-p-dioxin in splenic tissue of C57BL/6J mice.
C M Neumann, L B Steppan and N I Kerkvliet

Drug Metabolism and Disposition May 1992, 20 (3) 467-469;
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Glucosidation as a new conjugation pathway for metabolites of bis(2-ethylhexyl) phthalate.
B Egestad and P Sjöberg

Drug Metabolism and Disposition May 1992, 20 (3) 470-472;