Drug Metabolism and Disposition: 20 (5)

September 01, 1992; Volume 20,Issue 5

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Induction of CYP1A1 mRNA in rat epidermis and cultured human epidermal keratinocytes by benz(a)anthracene and beta-naphthoflavone.
I U Khan, D R Bickers, T M Haqqi and H Mukhtar

Drug Metabolism and Disposition September 1992, 20 (5) 620-624;
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Conjugation of dinitrofluorobenzene to plasma proteins in vivo in the rat.
N R Kitteringham, J G Kenna, C McLean, J B Clarke and B K Park

Drug Metabolism and Disposition September 1992, 20 (5) 625-631;
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Isolation, purification, and characterization of two new chemical decomposition products of methylazoxyprocarbazine.
D S Swaffar, W G Harker, S C Pomerantz, H K Lim and G S Yost

Drug Metabolism and Disposition September 1992, 20 (5) 632-642;
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Effects of dose, strain, and dosing vehicle on methacrylonitrile disposition in rats and identification of a novel-exhaled metabolite.
B I Ghanayem, I M Sanchez and L T Burka

Drug Metabolism and Disposition September 1992, 20 (5) 643-652;
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Pharmacokinetics and renal handling of enprofylline in pregnant rats.
I Muraoka, T Hasegawa, M Nadai, K Kato and T Nabeshima

Drug Metabolism and Disposition September 1992, 20 (5) 653-657;
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Species and tissue differences in the microsomal oxidation of 1,3-butadiene and the glutathione conjugation of butadiene monoxide in mice and rats. Possible role in 1,3-butadiene-induced toxicity.
J E Sharer, R J Duescher and A A Elfarra

Drug Metabolism and Disposition September 1992, 20 (5) 658-664;
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Identification and comparison of the urinary metabolites of [1,2,3-13C3]acrylic acid and [1,2,3-13C3]propionic acid in the rat by homonuclear 13C nuclear magnetic resonance spectroscopy.
S M Winter, G L Weber, P R Gooley, N E MacKenzie and I G Sipes

Drug Metabolism and Disposition September 1992, 20 (5) 665-672;
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Pharmacokinetics of intravenously injected [3H]tetrachloro(D,L-trans)1,2-diaminocyclohexane platinum (IV) (tetraplatin) in mice.
Y Kido, A R Khokhar and Z H Siddik

Drug Metabolism and Disposition September 1992, 20 (5) 673-678;
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Disposition of acrivastine in the male beagle dog.
M J McNulty, D L Deal, F R Nelson, S Weller, P Chandrasurin, J Shockcor and J W Findlay

Drug Metabolism and Disposition September 1992, 20 (5) 679-687;
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Bromo(monohydroxy)phenyl mercapturic acids. A new class of mercapturic acids from bromobenzene-treated rats.
J Zheng and R P Hanzlik

Drug Metabolism and Disposition September 1992, 20 (5) 688-694;
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Disposition of metabolically labeled recombinant soluble CD4 (sT4) in male Sprague-Dawley rats following intravenous and subcutaneous administration.
C B Davis, K E Boyle, J J Urbanski, R T Paradysz and K L Fong

Drug Metabolism and Disposition September 1992, 20 (5) 695-705;
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Pharmacokinetics and pharmacodynamics of topotecan in patients with advanced cancer.
L B Grochow, E K Rowinsky, R Johnson, S Ludeman, S H Kaufmann, F L McCabe, B R Smith, L Hurowitz, A DeLisa and R C Donehower

Drug Metabolism and Disposition September 1992, 20 (5) 706-713;
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Exogenous glutathione decreases cellular cadmium uptake and toxicity.
Y J Kang

Drug Metabolism and Disposition September 1992, 20 (5) 714-718;
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Enantioselectivity of microsomal and cytosolic esterases in rat intestinal mucosa.
S K Yang, Y Y Hsieh, W C Chang and J D Huang

Drug Metabolism and Disposition September 1992, 20 (5) 719-725;
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Concomitant induction of microsomal epoxide hydrolase and UDP-glucuronosyltransferase activities by dipyridine compounds.
M R Franklin and D E Moody

Drug Metabolism and Disposition September 1992, 20 (5) 726-729;
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Comparative pharmacokinetics of cefoperazone and cephradine in untreated streptozotocin diabetic rats.
E Nakashima, R Matsushita, M Takeda, T Nakanishi and F Ichimura

Drug Metabolism and Disposition September 1992, 20 (5) 730-735;
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The pharmacokinetics of 1,2-diethyl-3-hydroxypyridin-4-one (CP94) in rats.
O R Epemolu, S Singh, R C Hider and L A Damani

Drug Metabolism and Disposition September 1992, 20 (5) 736-741;
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Metabolism of 7-(1,3-thiazolidin-2-ylmethyl)theophylline by rat liver microsomes. Evidence for a monooxygenase-dependent step in 1,3-thiazolidine ring cleavage.
G Grosa, O Caputo, M Ceruti and G Biglino

Drug Metabolism and Disposition September 1992, 20 (5) 742-746;
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Pharmacokinetics in mice of the anti-retrovirus agent 9-(2-phosphonylmethoxyethyl)adenine.
L Naesens, J Balzarini and E De Clercq

Drug Metabolism and Disposition September 1992, 20 (5) 747-752;
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Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat.
M Sattler, F P Guengerich, C H Yun, U Christians and K F Sewing

Drug Metabolism and Disposition September 1992, 20 (5) 753-761;
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Isolation and structural characterization by spectroscopic methods of two glucuronide metabolites of mexiletine after N-oxidation and deamination.
J Turgeon, J R Paré, M Lalande, O Grech-Bélanger and P M Bélanger

Drug Metabolism and Disposition September 1992, 20 (5) 762-769;
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Cytochrome P-450-mediated N-dechloroethylation of cyclophosphamide and ifosfamide in the rat.
J A Ruzicka and P C Ruenitz

Drug Metabolism and Disposition September 1992, 20 (5) 770-772;
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Trimethadione metabolism as an index of hepatic drug-oxidizing capacity in dogs with liver ischemia.
E Tanaka, M Otsuka, K Yuzawa, A Isikawa, K Fukao and Y Iwasaki

Drug Metabolism and Disposition September 1992, 20 (5) 773-774;
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Inhibition of rabbit microsomal cytochrome P-450 2E1-dependent p-nitrophenol hydroxylation by substituted benzene derivatives.
D R Koop and C L Laethem

Drug Metabolism and Disposition September 1992, 20 (5) 775-777;

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