Drug Metabolism and Disposition: 20 (6)

November 01, 1992; Volume 20,Issue 6

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Peroxisome proliferators, a unique set of drug-metabolizing enzyme inducers: commentary on a symposium.
D E Moody, G G Gibson, D F Grant, J Magdalou and M S Rao

Drug Metabolism and Disposition November 1992, 20 (6) 779-791;
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Induction of P-450 cytochromes 2E2, 1A1, and 1A2 by imidazole in neonatal rabbits.
X Ding, H M Peng, S J Pernecky, C J Davis and M J Coon

Drug Metabolism and Disposition November 1992, 20 (6) 792-796;
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Phenobarbital and dexamethasone induce expression of cytochrome P-450 genes from subfamilies IIB, IIC, and IIIA in mouse liver.
L Corcos

Drug Metabolism and Disposition November 1992, 20 (6) 797-801;
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Cyclosporin A metabolism in human liver, kidney, and intestine slices. Comparison to rat and dog slices and human cell lines.
A E Vickers, V Fischer, S Connors, R L Fisher, J P Baldeck, G Maurer and K Brendel

Drug Metabolism and Disposition November 1992, 20 (6) 802-809;
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Pharmacokinetics and pharmacodynamics of valproate analogs in rats. III. Pharmacokinetics of valproic acid, cyclohexanecarboxylic acid, and 1-methyl-1-cyclohexanecarboxylic acid in the bile-exteriorized rat.
M J Liu, K L Brouwer and G M Pollack

Drug Metabolism and Disposition November 1992, 20 (6) 810-815;
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Metabolism of 3-tert-butyl-4-hydroxyanisole by horseradish peroxidase and hydrogen peroxide.
K Tajima, M Hashizaki, K Yamamoto and T Mizutani

Drug Metabolism and Disposition November 1992, 20 (6) 816-820;
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Simultaneous modeling of the pharmacokinetic and pharmacodynamic properties of enalkiren (Abbott-64662, a new renin inhibitor). I: Single dose study.
S K Gupta, G R Granneman, R S Boger, N K Hollenberg and R R Luther

Drug Metabolism and Disposition November 1992, 20 (6) 821-825;
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Pharmacokinetic profile of theophylline in isolated perfused liver of rabbits at different ages. Development of drug-metabolizing activity during ontogenesis.
M Corada, A Bortolotti, M M Barzago, A Celardo, M Bonati and A Guaitani

Drug Metabolism and Disposition November 1992, 20 (6) 826-831;
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Stereoselective sulfoxidation by human flavin-containing monooxygenase. Evidence for catalytic diversity between hepatic, renal, and fetal forms.
A J Sadeque, A C Eddy, G P Meier and A E Rettie

Drug Metabolism and Disposition November 1992, 20 (6) 832-839;
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Characterization of metabolites of xylazine produced in vivo and in vitro by LC/MS/MS and by GC/MS.
A E Mutlib, Y C Chui, L M Young and F S Abbott

Drug Metabolism and Disposition November 1992, 20 (6) 840-848;
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Metabolism and disposition of gemcitabine, and oncolytic deoxycytidine analog, in mice, rats, and dogs.
L A Shipley, T J Brown, J D Cornpropst, M Hamilton, W D Daniels and H W Culp

Drug Metabolism and Disposition November 1992, 20 (6) 849-855;
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Pharmacokinetics of oral methamphetamine and effects of repeated daily dosing in humans.
C E Cook, A R Jeffcoat, B M Sadler, J M Hill, R D Voyksner, D E Pugh, W R White and M Perez-Reyes

Drug Metabolism and Disposition November 1992, 20 (6) 856-862;
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Pharmacokinetic analysis of the metabolism of cocaine to norcocaine and N-hydroxynorcocaine in mice.
C S Boyer and D R Petersen

Drug Metabolism and Disposition November 1992, 20 (6) 863-868;
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Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (L-696,229), in rat and liver slices.
S K Balani, S M Pitzenberger, L R Kauffman, B H Arison, H G Ramjit, M E Goldman, J A O'Brien, J D King, J M Hoffman and C S Rooney

Drug Metabolism and Disposition November 1992, 20 (6) 869-876;
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Specific and enantioselective sulfoxidation of an aryl-trifluoromethyl sulfide by rat liver cytochromes P-450.
E Benoit, T Cresteil, J L Riviere and P Delatour

Drug Metabolism and Disposition November 1992, 20 (6) 877-881;
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Microbial models of mammalian metabolism. N-dealkylation of furosemide to yield the mammalian metabolite CSA using Cunninghamella elegans.
M Hezari and P J Davis

Drug Metabolism and Disposition November 1992, 20 (6) 882-888;
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Role of guinea pig and rabbit hepatic aldehyde oxidase in oxidative in vitro metabolism of cinchona antimalarials.
C Beedham, Y al-Tayib and J A Smith

Drug Metabolism and Disposition November 1992, 20 (6) 889-895;
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Studies on tertiary amine UDP-glucuronosyltransferases from human and rabbit hepatic microsomes.
P B Styczynski, M D Green, B Coffman and T R Tephly

Drug Metabolism and Disposition November 1992, 20 (6) 896-901;
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Substrates for microsomal azoreductase. Hammett substituent effects, NMR studies, and response to inhibitors.
S Zbaida, C F Brewer and W G Levine

Drug Metabolism and Disposition November 1992, 20 (6) 902-908;
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Pharmacokinetics of D(+)-usnic acid in rabbits after intravenous and oral administration.
D R Krishna and D Venkataramana

Drug Metabolism and Disposition November 1992, 20 (6) 909-911;
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Oxidation of carbovir, a carbocyclic nucleoside, by rat liver cytosolic enzymes. Enantioselectivity and enantiomeric inhibition.
J E Patanella and J S Walsh

Drug Metabolism and Disposition November 1992, 20 (6) 912-919;
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Disposition and metabolism of triprolidine in mice.
D L Deal, P Chandrasurin, J Shockcor, D J Minick, J W Findlay and M J McNulty

Drug Metabolism and Disposition November 1992, 20 (6) 920-927;
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Disposition of triprolidine in the male beagle dog.
M J McNulty, D L Deal, T L Page, P Chandrasurin and J W Findlay

Drug Metabolism and Disposition November 1992, 20 (6) 928-935;
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Clinical pharmacology of combined oral uracil and ftorafur.
D H Ho, W P Covington, R Pazdur, N S Brown, J Kuritani, R A Newman, M N Raber and I H Krakoff

Drug Metabolism and Disposition November 1992, 20 (6) 936-940;
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Investigation of conjugated metabolites of 4-hydroxyandrost-4-ene-3,17-dione in patient urine by liquid chromatography-atmospheric pressure ionization mass spectrometry.
G K Poon, Y C Chui, M Jarman, M G Rowlands, P S Kokkonen, W M Niessen and J van der Greef

Drug Metabolism and Disposition November 1992, 20 (6) 941-947;
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Oxidation of aldose reductase inhibitors ALO-4114 and ALO-3152 catalyzed by liver microsomes.
A D Kiss, K Haggard, J C Veltman and D M Ziegler

Drug Metabolism and Disposition November 1992, 20 (6) 948-953;
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Disposition of the human immunodeficiency virus Tat inhibitor, Ro 5-3335, in rats and dogs.
C Town, D Chang, L Henderson and W A Garland

Drug Metabolism and Disposition November 1992, 20 (6) 954-957;
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Formation of indenesulfonylureas in the metabolism of the anticancer agent sulofenur in rats, monkeys, and humans.
W J Ehlhardt, J L Zimmermann, J E Ray and J E Toth

Drug Metabolism and Disposition November 1992, 20 (6) 958-961;
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Covalent binding of etodolac acyl glucuronide to albumin in vitro.
P C Smith, W Q Song and R J Rodriguez

Drug Metabolism and Disposition November 1992, 20 (6) 962-965;

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