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Drug Metabolism & Disposition

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  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
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Index by author

November 01, 1992; Volume 20,Issue 6
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Abbott, F S

    1. You have access
      Characterization of metabolites of xylazine produced in vivo and in vitro by LC/MS/MS and by GC/MS.
      A E Mutlib, Y C Chui, L M Young and F S Abbott
      Drug Metabolism and Disposition November 1992, 20 (6) 840-848;
  2. al-Tayib, Y

    1. You have access
      Role of guinea pig and rabbit hepatic aldehyde oxidase in oxidative in vitro metabolism of cinchona antimalarials.
      C Beedham, Y al-Tayib and J A Smith
      Drug Metabolism and Disposition November 1992, 20 (6) 889-895;
  3. Arison, B H

    1. You have access
      Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (L-696,229), in rat and liver slices.
      S K Balani, S M Pitzenberger, L R Kauffman, B H Arison, H G Ramjit, M E Goldman, J A O'Brien, J D King, J M Hoffman and C S Rooney
      Drug Metabolism and Disposition November 1992, 20 (6) 869-876;

B

  1. Balani, S K

    1. You have access
      Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (L-696,229), in rat and liver slices.
      S K Balani, S M Pitzenberger, L R Kauffman, B H Arison, H G Ramjit, M E Goldman, J A O'Brien, J D King, J M Hoffman and C S Rooney
      Drug Metabolism and Disposition November 1992, 20 (6) 869-876;
  2. Baldeck, J P

    1. You have access
      Cyclosporin A metabolism in human liver, kidney, and intestine slices. Comparison to rat and dog slices and human cell lines.
      A E Vickers, V Fischer, S Connors, R L Fisher, J P Baldeck, G Maurer and K Brendel
      Drug Metabolism and Disposition November 1992, 20 (6) 802-809;
  3. Barzago, M M

    1. You have access
      Pharmacokinetic profile of theophylline in isolated perfused liver of rabbits at different ages. Development of drug-metabolizing activity during ontogenesis.
      M Corada, A Bortolotti, M M Barzago, A Celardo, M Bonati and A Guaitani
      Drug Metabolism and Disposition November 1992, 20 (6) 826-831;
  4. Beedham, C

    1. You have access
      Role of guinea pig and rabbit hepatic aldehyde oxidase in oxidative in vitro metabolism of cinchona antimalarials.
      C Beedham, Y al-Tayib and J A Smith
      Drug Metabolism and Disposition November 1992, 20 (6) 889-895;
  5. Benoit, E

    1. You have access
      Specific and enantioselective sulfoxidation of an aryl-trifluoromethyl sulfide by rat liver cytochromes P-450.
      E Benoit, T Cresteil, J L Riviere and P Delatour
      Drug Metabolism and Disposition November 1992, 20 (6) 877-881;
  6. Boger, R S

    1. You have access
      Simultaneous modeling of the pharmacokinetic and pharmacodynamic properties of enalkiren (Abbott-64662, a new renin inhibitor). I: Single dose study.
      S K Gupta, G R Granneman, R S Boger, N K Hollenberg and R R Luther
      Drug Metabolism and Disposition November 1992, 20 (6) 821-825;
  7. Bonati, M

    1. You have access
      Pharmacokinetic profile of theophylline in isolated perfused liver of rabbits at different ages. Development of drug-metabolizing activity during ontogenesis.
      M Corada, A Bortolotti, M M Barzago, A Celardo, M Bonati and A Guaitani
      Drug Metabolism and Disposition November 1992, 20 (6) 826-831;
  8. Bortolotti, A

    1. You have access
      Pharmacokinetic profile of theophylline in isolated perfused liver of rabbits at different ages. Development of drug-metabolizing activity during ontogenesis.
      M Corada, A Bortolotti, M M Barzago, A Celardo, M Bonati and A Guaitani
      Drug Metabolism and Disposition November 1992, 20 (6) 826-831;
  9. Boyer, C S

    1. You have access
      Pharmacokinetic analysis of the metabolism of cocaine to norcocaine and N-hydroxynorcocaine in mice.
      C S Boyer and D R Petersen
      Drug Metabolism and Disposition November 1992, 20 (6) 863-868;
  10. Brendel, K

    1. You have access
      Cyclosporin A metabolism in human liver, kidney, and intestine slices. Comparison to rat and dog slices and human cell lines.
      A E Vickers, V Fischer, S Connors, R L Fisher, J P Baldeck, G Maurer and K Brendel
      Drug Metabolism and Disposition November 1992, 20 (6) 802-809;
  11. Brewer, C F

    1. You have access
      Substrates for microsomal azoreductase. Hammett substituent effects, NMR studies, and response to inhibitors.
      S Zbaida, C F Brewer and W G Levine
      Drug Metabolism and Disposition November 1992, 20 (6) 902-908;
  12. Brouwer, K L

    1. You have access
      Pharmacokinetics and pharmacodynamics of valproate analogs in rats. III. Pharmacokinetics of valproic acid, cyclohexanecarboxylic acid, and 1-methyl-1-cyclohexanecarboxylic acid in the bile-exteriorized rat.
      M J Liu, K L Brouwer and G M Pollack
      Drug Metabolism and Disposition November 1992, 20 (6) 810-815;
  13. Brown, N S

    1. You have access
      Clinical pharmacology of combined oral uracil and ftorafur.
      D H Ho, W P Covington, R Pazdur, N S Brown, J Kuritani, R A Newman, M N Raber and I H Krakoff
      Drug Metabolism and Disposition November 1992, 20 (6) 936-940;
  14. Brown, T J

    1. You have access
      Metabolism and disposition of gemcitabine, and oncolytic deoxycytidine analog, in mice, rats, and dogs.
      L A Shipley, T J Brown, J D Cornpropst, M Hamilton, W D Daniels and H W Culp
      Drug Metabolism and Disposition November 1992, 20 (6) 849-855;

C

  1. Celardo, A

    1. You have access
      Pharmacokinetic profile of theophylline in isolated perfused liver of rabbits at different ages. Development of drug-metabolizing activity during ontogenesis.
      M Corada, A Bortolotti, M M Barzago, A Celardo, M Bonati and A Guaitani
      Drug Metabolism and Disposition November 1992, 20 (6) 826-831;
  2. Chandrasurin, P

    1. You have access
      Disposition and metabolism of triprolidine in mice.
      D L Deal, P Chandrasurin, J Shockcor, D J Minick, J W Findlay and M J McNulty
      Drug Metabolism and Disposition November 1992, 20 (6) 920-927;
    2. You have access
      Disposition of triprolidine in the male beagle dog.
      M J McNulty, D L Deal, T L Page, P Chandrasurin and J W Findlay
      Drug Metabolism and Disposition November 1992, 20 (6) 928-935;
  3. Chang, D

    1. You have access
      Disposition of the human immunodeficiency virus Tat inhibitor, Ro 5-3335, in rats and dogs.
      C Town, D Chang, L Henderson and W A Garland
      Drug Metabolism and Disposition November 1992, 20 (6) 954-957;
  4. Chui, Y C

    1. You have access
      Characterization of metabolites of xylazine produced in vivo and in vitro by LC/MS/MS and by GC/MS.
      A E Mutlib, Y C Chui, L M Young and F S Abbott
      Drug Metabolism and Disposition November 1992, 20 (6) 840-848;
    2. You have access
      Investigation of conjugated metabolites of 4-hydroxyandrost-4-ene-3,17-dione in patient urine by liquid chromatography-atmospheric pressure ionization mass spectrometry.
      G K Poon, Y C Chui, M Jarman, M G Rowlands, P S Kokkonen, W M Niessen and J van der Greef
      Drug Metabolism and Disposition November 1992, 20 (6) 941-947;
  5. Coffman, B

    1. You have access
      Studies on tertiary amine UDP-glucuronosyltransferases from human and rabbit hepatic microsomes.
      P B Styczynski, M D Green, B Coffman and T R Tephly
      Drug Metabolism and Disposition November 1992, 20 (6) 896-901;
  6. Connors, S

    1. You have access
      Cyclosporin A metabolism in human liver, kidney, and intestine slices. Comparison to rat and dog slices and human cell lines.
      A E Vickers, V Fischer, S Connors, R L Fisher, J P Baldeck, G Maurer and K Brendel
      Drug Metabolism and Disposition November 1992, 20 (6) 802-809;
  7. Cook, C E

    1. You have access
      Pharmacokinetics of oral methamphetamine and effects of repeated daily dosing in humans.
      C E Cook, A R Jeffcoat, B M Sadler, J M Hill, R D Voyksner, D E Pugh, W R White and M Perez-Reyes
      Drug Metabolism and Disposition November 1992, 20 (6) 856-862;
  8. Coon, M J

    1. You have access
      Induction of P-450 cytochromes 2E2, 1A1, and 1A2 by imidazole in neonatal rabbits.
      X Ding, H M Peng, S J Pernecky, C J Davis and M J Coon
      Drug Metabolism and Disposition November 1992, 20 (6) 792-796;
  9. Corada, M

    1. You have access
      Pharmacokinetic profile of theophylline in isolated perfused liver of rabbits at different ages. Development of drug-metabolizing activity during ontogenesis.
      M Corada, A Bortolotti, M M Barzago, A Celardo, M Bonati and A Guaitani
      Drug Metabolism and Disposition November 1992, 20 (6) 826-831;
  10. Corcos, L

    1. You have access
      Phenobarbital and dexamethasone induce expression of cytochrome P-450 genes from subfamilies IIB, IIC, and IIIA in mouse liver.
      L Corcos
      Drug Metabolism and Disposition November 1992, 20 (6) 797-801;
  11. Cornpropst, J D

    1. You have access
      Metabolism and disposition of gemcitabine, and oncolytic deoxycytidine analog, in mice, rats, and dogs.
      L A Shipley, T J Brown, J D Cornpropst, M Hamilton, W D Daniels and H W Culp
      Drug Metabolism and Disposition November 1992, 20 (6) 849-855;
  12. Covington, W P

    1. You have access
      Clinical pharmacology of combined oral uracil and ftorafur.
      D H Ho, W P Covington, R Pazdur, N S Brown, J Kuritani, R A Newman, M N Raber and I H Krakoff
      Drug Metabolism and Disposition November 1992, 20 (6) 936-940;
  13. Cresteil, T

    1. You have access
      Specific and enantioselective sulfoxidation of an aryl-trifluoromethyl sulfide by rat liver cytochromes P-450.
      E Benoit, T Cresteil, J L Riviere and P Delatour
      Drug Metabolism and Disposition November 1992, 20 (6) 877-881;
  14. Culp, H W

    1. You have access
      Metabolism and disposition of gemcitabine, and oncolytic deoxycytidine analog, in mice, rats, and dogs.
      L A Shipley, T J Brown, J D Cornpropst, M Hamilton, W D Daniels and H W Culp
      Drug Metabolism and Disposition November 1992, 20 (6) 849-855;

D

  1. Daniels, W D

    1. You have access
      Metabolism and disposition of gemcitabine, and oncolytic deoxycytidine analog, in mice, rats, and dogs.
      L A Shipley, T J Brown, J D Cornpropst, M Hamilton, W D Daniels and H W Culp
      Drug Metabolism and Disposition November 1992, 20 (6) 849-855;
  2. Davis, C J

    1. You have access
      Induction of P-450 cytochromes 2E2, 1A1, and 1A2 by imidazole in neonatal rabbits.
      X Ding, H M Peng, S J Pernecky, C J Davis and M J Coon
      Drug Metabolism and Disposition November 1992, 20 (6) 792-796;
  3. Davis, P J

    1. You have access
      Microbial models of mammalian metabolism. N-dealkylation of furosemide to yield the mammalian metabolite CSA using Cunninghamella elegans.
      M Hezari and P J Davis
      Drug Metabolism and Disposition November 1992, 20 (6) 882-888;
  4. Deal, D L

    1. You have access
      Disposition and metabolism of triprolidine in mice.
      D L Deal, P Chandrasurin, J Shockcor, D J Minick, J W Findlay and M J McNulty
      Drug Metabolism and Disposition November 1992, 20 (6) 920-927;
    2. You have access
      Disposition of triprolidine in the male beagle dog.
      M J McNulty, D L Deal, T L Page, P Chandrasurin and J W Findlay
      Drug Metabolism and Disposition November 1992, 20 (6) 928-935;
  5. Delatour, P

    1. You have access
      Specific and enantioselective sulfoxidation of an aryl-trifluoromethyl sulfide by rat liver cytochromes P-450.
      E Benoit, T Cresteil, J L Riviere and P Delatour
      Drug Metabolism and Disposition November 1992, 20 (6) 877-881;
  6. Ding, X

    1. You have access
      Induction of P-450 cytochromes 2E2, 1A1, and 1A2 by imidazole in neonatal rabbits.
      X Ding, H M Peng, S J Pernecky, C J Davis and M J Coon
      Drug Metabolism and Disposition November 1992, 20 (6) 792-796;

E

  1. Eddy, A C

    1. You have access
      Stereoselective sulfoxidation by human flavin-containing monooxygenase. Evidence for catalytic diversity between hepatic, renal, and fetal forms.
      A J Sadeque, A C Eddy, G P Meier and A E Rettie
      Drug Metabolism and Disposition November 1992, 20 (6) 832-839;
  2. Ehlhardt, W J

    1. You have access
      Formation of indenesulfonylureas in the metabolism of the anticancer agent sulofenur in rats, monkeys, and humans.
      W J Ehlhardt, J L Zimmermann, J E Ray and J E Toth
      Drug Metabolism and Disposition November 1992, 20 (6) 958-961;

F

  1. Findlay, J W

    1. You have access
      Disposition and metabolism of triprolidine in mice.
      D L Deal, P Chandrasurin, J Shockcor, D J Minick, J W Findlay and M J McNulty
      Drug Metabolism and Disposition November 1992, 20 (6) 920-927;
    2. You have access
      Disposition of triprolidine in the male beagle dog.
      M J McNulty, D L Deal, T L Page, P Chandrasurin and J W Findlay
      Drug Metabolism and Disposition November 1992, 20 (6) 928-935;
  2. Fischer, V

    1. You have access
      Cyclosporin A metabolism in human liver, kidney, and intestine slices. Comparison to rat and dog slices and human cell lines.
      A E Vickers, V Fischer, S Connors, R L Fisher, J P Baldeck, G Maurer and K Brendel
      Drug Metabolism and Disposition November 1992, 20 (6) 802-809;
  3. Fisher, R L

    1. You have access
      Cyclosporin A metabolism in human liver, kidney, and intestine slices. Comparison to rat and dog slices and human cell lines.
      A E Vickers, V Fischer, S Connors, R L Fisher, J P Baldeck, G Maurer and K Brendel
      Drug Metabolism and Disposition November 1992, 20 (6) 802-809;

G

  1. Garland, W A

    1. You have access
      Disposition of the human immunodeficiency virus Tat inhibitor, Ro 5-3335, in rats and dogs.
      C Town, D Chang, L Henderson and W A Garland
      Drug Metabolism and Disposition November 1992, 20 (6) 954-957;
  2. Gibson, G G

    1. You have access
      Peroxisome proliferators, a unique set of drug-metabolizing enzyme inducers: commentary on a symposium.
      D E Moody, G G Gibson, D F Grant, J Magdalou and M S Rao
      Drug Metabolism and Disposition November 1992, 20 (6) 779-791;
  3. Goldman, M E

    1. You have access
      Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (L-696,229), in rat and liver slices.
      S K Balani, S M Pitzenberger, L R Kauffman, B H Arison, H G Ramjit, M E Goldman, J A O'Brien, J D King, J M Hoffman and C S Rooney
      Drug Metabolism and Disposition November 1992, 20 (6) 869-876;
  4. Granneman, G R

    1. You have access
      Simultaneous modeling of the pharmacokinetic and pharmacodynamic properties of enalkiren (Abbott-64662, a new renin inhibitor). I: Single dose study.
      S K Gupta, G R Granneman, R S Boger, N K Hollenberg and R R Luther
      Drug Metabolism and Disposition November 1992, 20 (6) 821-825;
  5. Grant, D F

    1. You have access
      Peroxisome proliferators, a unique set of drug-metabolizing enzyme inducers: commentary on a symposium.
      D E Moody, G G Gibson, D F Grant, J Magdalou and M S Rao
      Drug Metabolism and Disposition November 1992, 20 (6) 779-791;
  6. Green, M D

    1. You have access
      Studies on tertiary amine UDP-glucuronosyltransferases from human and rabbit hepatic microsomes.
      P B Styczynski, M D Green, B Coffman and T R Tephly
      Drug Metabolism and Disposition November 1992, 20 (6) 896-901;
  7. Guaitani, A

    1. You have access
      Pharmacokinetic profile of theophylline in isolated perfused liver of rabbits at different ages. Development of drug-metabolizing activity during ontogenesis.
      M Corada, A Bortolotti, M M Barzago, A Celardo, M Bonati and A Guaitani
      Drug Metabolism and Disposition November 1992, 20 (6) 826-831;
  8. Gupta, S K

    1. You have access
      Simultaneous modeling of the pharmacokinetic and pharmacodynamic properties of enalkiren (Abbott-64662, a new renin inhibitor). I: Single dose study.
      S K Gupta, G R Granneman, R S Boger, N K Hollenberg and R R Luther
      Drug Metabolism and Disposition November 1992, 20 (6) 821-825;

H

  1. Haggard, K

    1. You have access
      Oxidation of aldose reductase inhibitors ALO-4114 and ALO-3152 catalyzed by liver microsomes.
      A D Kiss, K Haggard, J C Veltman and D M Ziegler
      Drug Metabolism and Disposition November 1992, 20 (6) 948-953;
  2. Hamilton, M

    1. You have access
      Metabolism and disposition of gemcitabine, and oncolytic deoxycytidine analog, in mice, rats, and dogs.
      L A Shipley, T J Brown, J D Cornpropst, M Hamilton, W D Daniels and H W Culp
      Drug Metabolism and Disposition November 1992, 20 (6) 849-855;
  3. Hashizaki, M

    1. You have access
      Metabolism of 3-tert-butyl-4-hydroxyanisole by horseradish peroxidase and hydrogen peroxide.
      K Tajima, M Hashizaki, K Yamamoto and T Mizutani
      Drug Metabolism and Disposition November 1992, 20 (6) 816-820;
  4. Henderson, L

    1. You have access
      Disposition of the human immunodeficiency virus Tat inhibitor, Ro 5-3335, in rats and dogs.
      C Town, D Chang, L Henderson and W A Garland
      Drug Metabolism and Disposition November 1992, 20 (6) 954-957;
  5. Hezari, M

    1. You have access
      Microbial models of mammalian metabolism. N-dealkylation of furosemide to yield the mammalian metabolite CSA using Cunninghamella elegans.
      M Hezari and P J Davis
      Drug Metabolism and Disposition November 1992, 20 (6) 882-888;
  6. Hill, J M

    1. You have access
      Pharmacokinetics of oral methamphetamine and effects of repeated daily dosing in humans.
      C E Cook, A R Jeffcoat, B M Sadler, J M Hill, R D Voyksner, D E Pugh, W R White and M Perez-Reyes
      Drug Metabolism and Disposition November 1992, 20 (6) 856-862;
  7. Ho, D H

    1. You have access
      Clinical pharmacology of combined oral uracil and ftorafur.
      D H Ho, W P Covington, R Pazdur, N S Brown, J Kuritani, R A Newman, M N Raber and I H Krakoff
      Drug Metabolism and Disposition November 1992, 20 (6) 936-940;
  8. Hoffman, J M

    1. You have access
      Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (L-696,229), in rat and liver slices.
      S K Balani, S M Pitzenberger, L R Kauffman, B H Arison, H G Ramjit, M E Goldman, J A O'Brien, J D King, J M Hoffman and C S Rooney
      Drug Metabolism and Disposition November 1992, 20 (6) 869-876;
  9. Hollenberg, N K

    1. You have access
      Simultaneous modeling of the pharmacokinetic and pharmacodynamic properties of enalkiren (Abbott-64662, a new renin inhibitor). I: Single dose study.
      S K Gupta, G R Granneman, R S Boger, N K Hollenberg and R R Luther
      Drug Metabolism and Disposition November 1992, 20 (6) 821-825;

J

  1. Jarman, M

    1. You have access
      Investigation of conjugated metabolites of 4-hydroxyandrost-4-ene-3,17-dione in patient urine by liquid chromatography-atmospheric pressure ionization mass spectrometry.
      G K Poon, Y C Chui, M Jarman, M G Rowlands, P S Kokkonen, W M Niessen and J van der Greef
      Drug Metabolism and Disposition November 1992, 20 (6) 941-947;
  2. Jeffcoat, A R

    1. You have access
      Pharmacokinetics of oral methamphetamine and effects of repeated daily dosing in humans.
      C E Cook, A R Jeffcoat, B M Sadler, J M Hill, R D Voyksner, D E Pugh, W R White and M Perez-Reyes
      Drug Metabolism and Disposition November 1992, 20 (6) 856-862;

K

  1. Kauffman, L R

    1. You have access
      Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (L-696,229), in rat and liver slices.
      S K Balani, S M Pitzenberger, L R Kauffman, B H Arison, H G Ramjit, M E Goldman, J A O'Brien, J D King, J M Hoffman and C S Rooney
      Drug Metabolism and Disposition November 1992, 20 (6) 869-876;
  2. King, J D

    1. You have access
      Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (L-696,229), in rat and liver slices.
      S K Balani, S M Pitzenberger, L R Kauffman, B H Arison, H G Ramjit, M E Goldman, J A O'Brien, J D King, J M Hoffman and C S Rooney
      Drug Metabolism and Disposition November 1992, 20 (6) 869-876;
  3. Kiss, A D

    1. You have access
      Oxidation of aldose reductase inhibitors ALO-4114 and ALO-3152 catalyzed by liver microsomes.
      A D Kiss, K Haggard, J C Veltman and D M Ziegler
      Drug Metabolism and Disposition November 1992, 20 (6) 948-953;
  4. Kokkonen, P S

    1. You have access
      Investigation of conjugated metabolites of 4-hydroxyandrost-4-ene-3,17-dione in patient urine by liquid chromatography-atmospheric pressure ionization mass spectrometry.
      G K Poon, Y C Chui, M Jarman, M G Rowlands, P S Kokkonen, W M Niessen and J van der Greef
      Drug Metabolism and Disposition November 1992, 20 (6) 941-947;
  5. Krakoff, I H

    1. You have access
      Clinical pharmacology of combined oral uracil and ftorafur.
      D H Ho, W P Covington, R Pazdur, N S Brown, J Kuritani, R A Newman, M N Raber and I H Krakoff
      Drug Metabolism and Disposition November 1992, 20 (6) 936-940;
  6. Krishna, D R

    1. You have access
      Pharmacokinetics of D(+)-usnic acid in rabbits after intravenous and oral administration.
      D R Krishna and D Venkataramana
      Drug Metabolism and Disposition November 1992, 20 (6) 909-911;
  7. Kuritani, J

    1. You have access
      Clinical pharmacology of combined oral uracil and ftorafur.
      D H Ho, W P Covington, R Pazdur, N S Brown, J Kuritani, R A Newman, M N Raber and I H Krakoff
      Drug Metabolism and Disposition November 1992, 20 (6) 936-940;

L

  1. Levine, W G

    1. You have access
      Substrates for microsomal azoreductase. Hammett substituent effects, NMR studies, and response to inhibitors.
      S Zbaida, C F Brewer and W G Levine
      Drug Metabolism and Disposition November 1992, 20 (6) 902-908;
  2. Liu, M J

    1. You have access
      Pharmacokinetics and pharmacodynamics of valproate analogs in rats. III. Pharmacokinetics of valproic acid, cyclohexanecarboxylic acid, and 1-methyl-1-cyclohexanecarboxylic acid in the bile-exteriorized rat.
      M J Liu, K L Brouwer and G M Pollack
      Drug Metabolism and Disposition November 1992, 20 (6) 810-815;
  3. Luther, R R

    1. You have access
      Simultaneous modeling of the pharmacokinetic and pharmacodynamic properties of enalkiren (Abbott-64662, a new renin inhibitor). I: Single dose study.
      S K Gupta, G R Granneman, R S Boger, N K Hollenberg and R R Luther
      Drug Metabolism and Disposition November 1992, 20 (6) 821-825;

M

  1. Magdalou, J

    1. You have access
      Peroxisome proliferators, a unique set of drug-metabolizing enzyme inducers: commentary on a symposium.
      D E Moody, G G Gibson, D F Grant, J Magdalou and M S Rao
      Drug Metabolism and Disposition November 1992, 20 (6) 779-791;
  2. Maurer, G

    1. You have access
      Cyclosporin A metabolism in human liver, kidney, and intestine slices. Comparison to rat and dog slices and human cell lines.
      A E Vickers, V Fischer, S Connors, R L Fisher, J P Baldeck, G Maurer and K Brendel
      Drug Metabolism and Disposition November 1992, 20 (6) 802-809;
  3. McNulty, M J

    1. You have access
      Disposition and metabolism of triprolidine in mice.
      D L Deal, P Chandrasurin, J Shockcor, D J Minick, J W Findlay and M J McNulty
      Drug Metabolism and Disposition November 1992, 20 (6) 920-927;
    2. You have access
      Disposition of triprolidine in the male beagle dog.
      M J McNulty, D L Deal, T L Page, P Chandrasurin and J W Findlay
      Drug Metabolism and Disposition November 1992, 20 (6) 928-935;
  4. Meier, G P

    1. You have access
      Stereoselective sulfoxidation by human flavin-containing monooxygenase. Evidence for catalytic diversity between hepatic, renal, and fetal forms.
      A J Sadeque, A C Eddy, G P Meier and A E Rettie
      Drug Metabolism and Disposition November 1992, 20 (6) 832-839;
  5. Minick, D J

    1. You have access
      Disposition and metabolism of triprolidine in mice.
      D L Deal, P Chandrasurin, J Shockcor, D J Minick, J W Findlay and M J McNulty
      Drug Metabolism and Disposition November 1992, 20 (6) 920-927;
  6. Mizutani, T

    1. You have access
      Metabolism of 3-tert-butyl-4-hydroxyanisole by horseradish peroxidase and hydrogen peroxide.
      K Tajima, M Hashizaki, K Yamamoto and T Mizutani
      Drug Metabolism and Disposition November 1992, 20 (6) 816-820;
  7. Moody, D E

    1. You have access
      Peroxisome proliferators, a unique set of drug-metabolizing enzyme inducers: commentary on a symposium.
      D E Moody, G G Gibson, D F Grant, J Magdalou and M S Rao
      Drug Metabolism and Disposition November 1992, 20 (6) 779-791;
  8. Mutlib, A E

    1. You have access
      Characterization of metabolites of xylazine produced in vivo and in vitro by LC/MS/MS and by GC/MS.
      A E Mutlib, Y C Chui, L M Young and F S Abbott
      Drug Metabolism and Disposition November 1992, 20 (6) 840-848;

N

  1. Newman, R A

    1. You have access
      Clinical pharmacology of combined oral uracil and ftorafur.
      D H Ho, W P Covington, R Pazdur, N S Brown, J Kuritani, R A Newman, M N Raber and I H Krakoff
      Drug Metabolism and Disposition November 1992, 20 (6) 936-940;
  2. Niessen, W M

    1. You have access
      Investigation of conjugated metabolites of 4-hydroxyandrost-4-ene-3,17-dione in patient urine by liquid chromatography-atmospheric pressure ionization mass spectrometry.
      G K Poon, Y C Chui, M Jarman, M G Rowlands, P S Kokkonen, W M Niessen and J van der Greef
      Drug Metabolism and Disposition November 1992, 20 (6) 941-947;

O

  1. O'Brien, J A

    1. You have access
      Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (L-696,229), in rat and liver slices.
      S K Balani, S M Pitzenberger, L R Kauffman, B H Arison, H G Ramjit, M E Goldman, J A O'Brien, J D King, J M Hoffman and C S Rooney
      Drug Metabolism and Disposition November 1992, 20 (6) 869-876;

P

  1. Page, T L

    1. You have access
      Disposition of triprolidine in the male beagle dog.
      M J McNulty, D L Deal, T L Page, P Chandrasurin and J W Findlay
      Drug Metabolism and Disposition November 1992, 20 (6) 928-935;
  2. Patanella, J E

    1. You have access
      Oxidation of carbovir, a carbocyclic nucleoside, by rat liver cytosolic enzymes. Enantioselectivity and enantiomeric inhibition.
      J E Patanella and J S Walsh
      Drug Metabolism and Disposition November 1992, 20 (6) 912-919;
  3. Pazdur, R

    1. You have access
      Clinical pharmacology of combined oral uracil and ftorafur.
      D H Ho, W P Covington, R Pazdur, N S Brown, J Kuritani, R A Newman, M N Raber and I H Krakoff
      Drug Metabolism and Disposition November 1992, 20 (6) 936-940;
  4. Peng, H M

    1. You have access
      Induction of P-450 cytochromes 2E2, 1A1, and 1A2 by imidazole in neonatal rabbits.
      X Ding, H M Peng, S J Pernecky, C J Davis and M J Coon
      Drug Metabolism and Disposition November 1992, 20 (6) 792-796;
  5. Perez-Reyes, M

    1. You have access
      Pharmacokinetics of oral methamphetamine and effects of repeated daily dosing in humans.
      C E Cook, A R Jeffcoat, B M Sadler, J M Hill, R D Voyksner, D E Pugh, W R White and M Perez-Reyes
      Drug Metabolism and Disposition November 1992, 20 (6) 856-862;
  6. Pernecky, S J

    1. You have access
      Induction of P-450 cytochromes 2E2, 1A1, and 1A2 by imidazole in neonatal rabbits.
      X Ding, H M Peng, S J Pernecky, C J Davis and M J Coon
      Drug Metabolism and Disposition November 1992, 20 (6) 792-796;
  7. Petersen, D R

    1. You have access
      Pharmacokinetic analysis of the metabolism of cocaine to norcocaine and N-hydroxynorcocaine in mice.
      C S Boyer and D R Petersen
      Drug Metabolism and Disposition November 1992, 20 (6) 863-868;
  8. Pitzenberger, S M

    1. You have access
      Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (L-696,229), in rat and liver slices.
      S K Balani, S M Pitzenberger, L R Kauffman, B H Arison, H G Ramjit, M E Goldman, J A O'Brien, J D King, J M Hoffman and C S Rooney
      Drug Metabolism and Disposition November 1992, 20 (6) 869-876;
  9. Pollack, G M

    1. You have access
      Pharmacokinetics and pharmacodynamics of valproate analogs in rats. III. Pharmacokinetics of valproic acid, cyclohexanecarboxylic acid, and 1-methyl-1-cyclohexanecarboxylic acid in the bile-exteriorized rat.
      M J Liu, K L Brouwer and G M Pollack
      Drug Metabolism and Disposition November 1992, 20 (6) 810-815;
  10. Poon, G K

    1. You have access
      Investigation of conjugated metabolites of 4-hydroxyandrost-4-ene-3,17-dione in patient urine by liquid chromatography-atmospheric pressure ionization mass spectrometry.
      G K Poon, Y C Chui, M Jarman, M G Rowlands, P S Kokkonen, W M Niessen and J van der Greef
      Drug Metabolism and Disposition November 1992, 20 (6) 941-947;
  11. Pugh, D E

    1. You have access
      Pharmacokinetics of oral methamphetamine and effects of repeated daily dosing in humans.
      C E Cook, A R Jeffcoat, B M Sadler, J M Hill, R D Voyksner, D E Pugh, W R White and M Perez-Reyes
      Drug Metabolism and Disposition November 1992, 20 (6) 856-862;

R

  1. Raber, M N

    1. You have access
      Clinical pharmacology of combined oral uracil and ftorafur.
      D H Ho, W P Covington, R Pazdur, N S Brown, J Kuritani, R A Newman, M N Raber and I H Krakoff
      Drug Metabolism and Disposition November 1992, 20 (6) 936-940;
  2. Ramjit, H G

    1. You have access
      Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (L-696,229), in rat and liver slices.
      S K Balani, S M Pitzenberger, L R Kauffman, B H Arison, H G Ramjit, M E Goldman, J A O'Brien, J D King, J M Hoffman and C S Rooney
      Drug Metabolism and Disposition November 1992, 20 (6) 869-876;
  3. Rao, M S

    1. You have access
      Peroxisome proliferators, a unique set of drug-metabolizing enzyme inducers: commentary on a symposium.
      D E Moody, G G Gibson, D F Grant, J Magdalou and M S Rao
      Drug Metabolism and Disposition November 1992, 20 (6) 779-791;
  4. Ray, J E

    1. You have access
      Formation of indenesulfonylureas in the metabolism of the anticancer agent sulofenur in rats, monkeys, and humans.
      W J Ehlhardt, J L Zimmermann, J E Ray and J E Toth
      Drug Metabolism and Disposition November 1992, 20 (6) 958-961;
  5. Rettie, A E

    1. You have access
      Stereoselective sulfoxidation by human flavin-containing monooxygenase. Evidence for catalytic diversity between hepatic, renal, and fetal forms.
      A J Sadeque, A C Eddy, G P Meier and A E Rettie
      Drug Metabolism and Disposition November 1992, 20 (6) 832-839;
  6. Riviere, J L

    1. You have access
      Specific and enantioselective sulfoxidation of an aryl-trifluoromethyl sulfide by rat liver cytochromes P-450.
      E Benoit, T Cresteil, J L Riviere and P Delatour
      Drug Metabolism and Disposition November 1992, 20 (6) 877-881;
  7. Rodriguez, R J

    1. You have access
      Covalent binding of etodolac acyl glucuronide to albumin in vitro.
      P C Smith, W Q Song and R J Rodriguez
      Drug Metabolism and Disposition November 1992, 20 (6) 962-965;
  8. Rooney, C S

    1. You have access
      Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (L-696,229), in rat and liver slices.
      S K Balani, S M Pitzenberger, L R Kauffman, B H Arison, H G Ramjit, M E Goldman, J A O'Brien, J D King, J M Hoffman and C S Rooney
      Drug Metabolism and Disposition November 1992, 20 (6) 869-876;
  9. Rowlands, M G

    1. You have access
      Investigation of conjugated metabolites of 4-hydroxyandrost-4-ene-3,17-dione in patient urine by liquid chromatography-atmospheric pressure ionization mass spectrometry.
      G K Poon, Y C Chui, M Jarman, M G Rowlands, P S Kokkonen, W M Niessen and J van der Greef
      Drug Metabolism and Disposition November 1992, 20 (6) 941-947;

S

  1. Sadeque, A J

    1. You have access
      Stereoselective sulfoxidation by human flavin-containing monooxygenase. Evidence for catalytic diversity between hepatic, renal, and fetal forms.
      A J Sadeque, A C Eddy, G P Meier and A E Rettie
      Drug Metabolism and Disposition November 1992, 20 (6) 832-839;
  2. Sadler, B M

    1. You have access
      Pharmacokinetics of oral methamphetamine and effects of repeated daily dosing in humans.
      C E Cook, A R Jeffcoat, B M Sadler, J M Hill, R D Voyksner, D E Pugh, W R White and M Perez-Reyes
      Drug Metabolism and Disposition November 1992, 20 (6) 856-862;
  3. Shipley, L A

    1. You have access
      Metabolism and disposition of gemcitabine, and oncolytic deoxycytidine analog, in mice, rats, and dogs.
      L A Shipley, T J Brown, J D Cornpropst, M Hamilton, W D Daniels and H W Culp
      Drug Metabolism and Disposition November 1992, 20 (6) 849-855;
  4. Shockcor, J

    1. You have access
      Disposition and metabolism of triprolidine in mice.
      D L Deal, P Chandrasurin, J Shockcor, D J Minick, J W Findlay and M J McNulty
      Drug Metabolism and Disposition November 1992, 20 (6) 920-927;
  5. Smith, J A

    1. You have access
      Role of guinea pig and rabbit hepatic aldehyde oxidase in oxidative in vitro metabolism of cinchona antimalarials.
      C Beedham, Y al-Tayib and J A Smith
      Drug Metabolism and Disposition November 1992, 20 (6) 889-895;
  6. Smith, P C

    1. You have access
      Covalent binding of etodolac acyl glucuronide to albumin in vitro.
      P C Smith, W Q Song and R J Rodriguez
      Drug Metabolism and Disposition November 1992, 20 (6) 962-965;
  7. Song, W Q

    1. You have access
      Covalent binding of etodolac acyl glucuronide to albumin in vitro.
      P C Smith, W Q Song and R J Rodriguez
      Drug Metabolism and Disposition November 1992, 20 (6) 962-965;
  8. Styczynski, P B

    1. You have access
      Studies on tertiary amine UDP-glucuronosyltransferases from human and rabbit hepatic microsomes.
      P B Styczynski, M D Green, B Coffman and T R Tephly
      Drug Metabolism and Disposition November 1992, 20 (6) 896-901;

T

  1. Tajima, K

    1. You have access
      Metabolism of 3-tert-butyl-4-hydroxyanisole by horseradish peroxidase and hydrogen peroxide.
      K Tajima, M Hashizaki, K Yamamoto and T Mizutani
      Drug Metabolism and Disposition November 1992, 20 (6) 816-820;
  2. Tephly, T R

    1. You have access
      Studies on tertiary amine UDP-glucuronosyltransferases from human and rabbit hepatic microsomes.
      P B Styczynski, M D Green, B Coffman and T R Tephly
      Drug Metabolism and Disposition November 1992, 20 (6) 896-901;
  3. Toth, J E

    1. You have access
      Formation of indenesulfonylureas in the metabolism of the anticancer agent sulofenur in rats, monkeys, and humans.
      W J Ehlhardt, J L Zimmermann, J E Ray and J E Toth
      Drug Metabolism and Disposition November 1992, 20 (6) 958-961;
  4. Town, C

    1. You have access
      Disposition of the human immunodeficiency virus Tat inhibitor, Ro 5-3335, in rats and dogs.
      C Town, D Chang, L Henderson and W A Garland
      Drug Metabolism and Disposition November 1992, 20 (6) 954-957;

V

  1. van der Greef, J

    1. You have access
      Investigation of conjugated metabolites of 4-hydroxyandrost-4-ene-3,17-dione in patient urine by liquid chromatography-atmospheric pressure ionization mass spectrometry.
      G K Poon, Y C Chui, M Jarman, M G Rowlands, P S Kokkonen, W M Niessen and J van der Greef
      Drug Metabolism and Disposition November 1992, 20 (6) 941-947;
  2. Veltman, J C

    1. You have access
      Oxidation of aldose reductase inhibitors ALO-4114 and ALO-3152 catalyzed by liver microsomes.
      A D Kiss, K Haggard, J C Veltman and D M Ziegler
      Drug Metabolism and Disposition November 1992, 20 (6) 948-953;
  3. Venkataramana, D

    1. You have access
      Pharmacokinetics of D(+)-usnic acid in rabbits after intravenous and oral administration.
      D R Krishna and D Venkataramana
      Drug Metabolism and Disposition November 1992, 20 (6) 909-911;
  4. Vickers, A E

    1. You have access
      Cyclosporin A metabolism in human liver, kidney, and intestine slices. Comparison to rat and dog slices and human cell lines.
      A E Vickers, V Fischer, S Connors, R L Fisher, J P Baldeck, G Maurer and K Brendel
      Drug Metabolism and Disposition November 1992, 20 (6) 802-809;
  5. Voyksner, R D

    1. You have access
      Pharmacokinetics of oral methamphetamine and effects of repeated daily dosing in humans.
      C E Cook, A R Jeffcoat, B M Sadler, J M Hill, R D Voyksner, D E Pugh, W R White and M Perez-Reyes
      Drug Metabolism and Disposition November 1992, 20 (6) 856-862;

W

  1. Walsh, J S

    1. You have access
      Oxidation of carbovir, a carbocyclic nucleoside, by rat liver cytosolic enzymes. Enantioselectivity and enantiomeric inhibition.
      J E Patanella and J S Walsh
      Drug Metabolism and Disposition November 1992, 20 (6) 912-919;
  2. White, W R

    1. You have access
      Pharmacokinetics of oral methamphetamine and effects of repeated daily dosing in humans.
      C E Cook, A R Jeffcoat, B M Sadler, J M Hill, R D Voyksner, D E Pugh, W R White and M Perez-Reyes
      Drug Metabolism and Disposition November 1992, 20 (6) 856-862;

Y

  1. Yamamoto, K

    1. You have access
      Metabolism of 3-tert-butyl-4-hydroxyanisole by horseradish peroxidase and hydrogen peroxide.
      K Tajima, M Hashizaki, K Yamamoto and T Mizutani
      Drug Metabolism and Disposition November 1992, 20 (6) 816-820;
  2. Young, L M

    1. You have access
      Characterization of metabolites of xylazine produced in vivo and in vitro by LC/MS/MS and by GC/MS.
      A E Mutlib, Y C Chui, L M Young and F S Abbott
      Drug Metabolism and Disposition November 1992, 20 (6) 840-848;

Z

  1. Zbaida, S

    1. You have access
      Substrates for microsomal azoreductase. Hammett substituent effects, NMR studies, and response to inhibitors.
      S Zbaida, C F Brewer and W G Levine
      Drug Metabolism and Disposition November 1992, 20 (6) 902-908;
  2. Ziegler, D M

    1. You have access
      Oxidation of aldose reductase inhibitors ALO-4114 and ALO-3152 catalyzed by liver microsomes.
      A D Kiss, K Haggard, J C Veltman and D M Ziegler
      Drug Metabolism and Disposition November 1992, 20 (6) 948-953;
  3. Zimmermann, J L

    1. You have access
      Formation of indenesulfonylureas in the metabolism of the anticancer agent sulofenur in rats, monkeys, and humans.
      W J Ehlhardt, J L Zimmermann, J E Ray and J E Toth
      Drug Metabolism and Disposition November 1992, 20 (6) 958-961;
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In this issue

Drug Metabolism and Disposition
Vol. 20, Issue 6
1 Nov 1992
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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