Drug Metabolism and Disposition: 21 (1)

January 01, 1993; Volume 21,Issue 1

You have access
The 1992 Bernard B. Brodie Award Lecture. Bioactivation and detoxication of toxic and carcinogenic chemicals.
F P Guengerich

Drug Metabolism and Disposition January 1993, 21 (1) 1-6;
You have access
In vivo and in vitro effect of cimetidine, inflammation, and hypoxia on propofol kinetics.
G Audibert, C G Saunier and P du Souich

Drug Metabolism and Disposition January 1993, 21 (1) 7-12;
You have access
Uptake, 3-, and 6-glucuronidation of morphine in isolated cells from stomach, intestine, colon, and liver of the guinea pig.
P Déchelotte, A Sabouraud, P Sandouk, I Hackbarth and M Schwenk

Drug Metabolism and Disposition January 1993, 21 (1) 13-17;
You have access
Evidence that famciclovir (BRL 42810) and its associated metabolites do not inhibit the 6 beta-hydroxylation of testosterone in human liver microsomes.
A W Harrell, S M Wheeler, M Pennick, S E Clarke and R J Chenery

Drug Metabolism and Disposition January 1993, 21 (1) 18-23;
You have access
Oxidation of desmethylpromethazine catalyzed by pig liver flavin-containing monooxygenase. Number and nature of metabolites.
B Clement, K L Lustig and D M Ziegler

Drug Metabolism and Disposition January 1993, 21 (1) 24-29;
You have access
Reduction of cisplatin nephrotoxicity by sodium selenite. Lack of interaction at the pharmacokinetic level of both compounds.
N P Vermeulen, G S Baldew, G Los, J G McVie and J J De Goeij

Drug Metabolism and Disposition January 1993, 21 (1) 30-36;
You have access
Evidence for peroxidase-mediated metabolism of cyclophosphamide.
S Kanekal and J P Kehrer

Drug Metabolism and Disposition January 1993, 21 (1) 37-42;
You have access
Caffeine, estradiol, and progesterone interact with human CYP1A1 and CYP1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae.
H P Eugster, M Probst, F E Würgler and C Sengstag

Drug Metabolism and Disposition January 1993, 21 (1) 43-49;
You have access
Substrate specificities of two stably expressed human liver UDP-glucuronosyltransferases of the UGT1 gene family.
T Ebner and B Burchell

Drug Metabolism and Disposition January 1993, 21 (1) 50-55;
You have access
Inducibility of enzyme activities associated with the cytochrome P-450 1A family, ethoxyresorufin O-deethylase, and methoxyresorufin O-demethylase in human hepatocyte lines derived from normal liver tissue.
E A Roberts, Z W Xie, S Yang and J Lipa

Drug Metabolism and Disposition January 1993, 21 (1) 56-61;
You have access
Pharmacokinetics and disposition in the rat of a DNA intercalator 502U83.
D K Patel, R P Lewis, M L Hinton, D H Schroeder, J P Shockcor, R L Johnson and C W Sigel

Drug Metabolism and Disposition January 1993, 21 (1) 62-70;
You have access
Altered pharmacokinetics of recombinant human deoxyribonuclease in rats due to the presence of a binding protein.
M Mohler, J Cook, D Lewis, J Moore, D Sinicropi, A Championsmith, B Ferraiolo and J Mordenti

Drug Metabolism and Disposition January 1993, 21 (1) 71-75;
You have access
Stereoselective sulfation of albuterol in humans. Biosynthesis of the sulfate conjugate by HEP G2 cells.
T Walle, U K Walle, K R Thornburg and K L Schey

Drug Metabolism and Disposition January 1993, 21 (1) 76-80;
You have access
Identification of major metabolites of the catechol-O-methyltransferase inhibitor entacapone in rats and humans.
T Wikberg, A Vuorela, P Ottoila and J Taskinen

Drug Metabolism and Disposition January 1993, 21 (1) 81-92;
You have access
Main urinary metabolites of two cysteamine-containing 2-(chloroethyl) nitrosoureas in rats.
D Godeneche, P Labarre, M F Moreau, J C Madelmont, M Rapp, J Papon and A Veyre

Drug Metabolism and Disposition January 1993, 21 (1) 93-99;
You have access
Clearance and tissue uptake following 4-hour and 24-hour infusions of pamidronate in rats.
M Pongchaidecha and P T Daley-Yates

Drug Metabolism and Disposition January 1993, 21 (1) 100-104;
You have access
Fluorine NMR studies of the metabolism of flumecinol (3-trifluoromethyl-alpha-ethylbenzhydrol).
L A Sylvia and J T Gerig

Drug Metabolism and Disposition January 1993, 21 (1) 105-113;
You have access
Metabolic inversion of (R)-ibuprofen. Formation of ibuprofenyl-coenzyme A.
T S Tracy, D P Wirthwein and S D Hall

Drug Metabolism and Disposition January 1993, 21 (1) 114-120;
You have access
A simplified methodology for quantitation of butadiene metabolites. Application to the study of 1,3-butadiene metabolism by rat liver microsomes.
X Cheng and J A Ruth

Drug Metabolism and Disposition January 1993, 21 (1) 121-124;
You have access
A pharmacokinetic study of phenylcyclohexyldiethylamine. An analog of phencyclidine.
A K Cho, M Hiramatsu, D A Schmitz, E M Landaw, A S Chang, S Ramamurthy and D J Jenden

Drug Metabolism and Disposition January 1993, 21 (1) 125-132;
You have access
Metabolism of N,N-diethylbenzamide and N,N-diethyl-alpha,alpha'-13C-benzamide by rat liver microsomes.
W G Taylor, T W Hall and D D Vedres

Drug Metabolism and Disposition January 1993, 21 (1) 133-140;
You have access
Effect of atropine on gastrointestinal motility and the bioavailability of cyclosporine A in rats.
R F Quijano, N Ohnishi, K Umeda, F Komada, S Iwakawa and K Okumura

Drug Metabolism and Disposition January 1993, 21 (1) 141-143;
You have access
Pharmacokinetics of recombinant human follicle stimulating hormone after intravenous, intramuscular, and subcutaneous administration in monkeys, and comparison with intravenous administration of urinary follicle stimulating hormone.
H C Porchet, J Y Le Cotonnec, S Canali and G Zanolo

Drug Metabolism and Disposition January 1993, 21 (1) 144-150;
You have access
In vivo glucuronidation in rat and humans of 5,6-dihydro-7-(1H-imidazol-1-yl)-naphthalene-2-carboxylic acid, a selective inhibitor of thromboxane synthase.
J Thomassin, R Battaglia, C Allievi, M G Castelli and M Strolin Benedetti

Drug Metabolism and Disposition January 1993, 21 (1) 151-155;
You have access
Effects of propranolol on the disposition and negative dromotropic activity of diltiazem in the dog during multiple dosing.
C Maskasame, S M Lankford and S A Bai

Drug Metabolism and Disposition January 1993, 21 (1) 156-161;
You have access
Biotransformation of the antiviral agent 1,3,4-thiadiazol-2-ylcyanamide (LY217896) and characteristics of a mesoionic ribose metabolite.
W J Ehlhardt, W J Wheeler, A P Breau, S H Chay and G M Birch

Drug Metabolism and Disposition January 1993, 21 (1) 162-170;
You have access
Disposition of oral [14C]cefcanel daloxate hydrochloride in healthy male subjects.
B Edwall, A Arvidsson, D Lake-Bakaar, K Lanbeck-Vallén and W Yisak

Drug Metabolism and Disposition January 1993, 21 (1) 171-177;
You have access
Caffeine metabolism in liver slices during postnatal development in rats.
T Bienvenu, G Pons, E Rey, G Thiroux and G Olive

Drug Metabolism and Disposition January 1993, 21 (1) 178-180;
You have access
Inhibition of human red blood cell N-acetyltransferase.
R A Voice, M Manis and W W Weber

Drug Metabolism and Disposition January 1993, 21 (1) 181-183;
You have access
Hepatic elimination in the rat of ditekiren (U-71038), a renin inhibitor pseudohexapeptide.
A Adedoyin, P R Perry and G R Wilkinson

Drug Metabolism and Disposition January 1993, 21 (1) 184-188;
You have access
Zidovudine bioavailability and linear pharmacokinetics in female B6C3F1 mice.
J M Trang, J D Prejean, R H James, R D Irwin, T J Goehl and J G Page

Drug Metabolism and Disposition January 1993, 21 (1) 189-193;
You have access
Biometabolic elimination and organ retention profile of argemone alkaloid, sanguinarine, in rats and guinea pigs.
S Tandon, M Das and S K Khanna

Drug Metabolism and Disposition January 1993, 21 (1) 194-197;
You have access
Identification of two novel indolic metabolites of (R),(R)-labetalol in monkey urine.
K B Alton, T M Chan and B Pramanik

Drug Metabolism and Disposition January 1993, 21 (1) 198-199;
You have access
Zonal differences in the thermal lability of adrenal microsomal monooxygenases.
H D Colby, M Levitt and I W Larson

Drug Metabolism and Disposition January 1993, 21 (1) 200-202;

Main menu

User menu

Search

Table of Contents

In this issue

Navigate

More Information

ASPET's Other Journals