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Index by author

January 01, 1993; Volume 21,Issue 1

A

  1. Adedoyin, A

    1. Hepatic elimination in the rat of ditekiren (U-71038), a renin inhibitor pseudohexapeptide.
      A Adedoyin, P R Perry and G R Wilkinson
      Drug Metabolism and Disposition January 1993, 21 (1) 184-188;

  2. Allievi, C

    1. In vivo glucuronidation in rat and humans of 5,6-dihydro-7-(1H-imidazol-1-yl)-naphthalene-2-carboxylic acid, a selective inhibitor of thromboxane synthase.
      J Thomassin, R Battaglia, C Allievi, M G Castelli and M Strolin Benedetti
      Drug Metabolism and Disposition January 1993, 21 (1) 151-155;

  3. Alton, K B

    1. Identification of two novel indolic metabolites of (R),(R)-labetalol in monkey urine.
      K B Alton, T M Chan and B Pramanik
      Drug Metabolism and Disposition January 1993, 21 (1) 198-199;

  4. Arvidsson, A

    1. Disposition of oral [14C]cefcanel daloxate hydrochloride in healthy male subjects.
      B Edwall, A Arvidsson, D Lake-Bakaar, K Lanbeck-Vallén and W Yisak
      Drug Metabolism and Disposition January 1993, 21 (1) 171-177;

  5. Audibert, G

    1. In vivo and in vitro effect of cimetidine, inflammation, and hypoxia on propofol kinetics.
      G Audibert, C G Saunier and P du Souich
      Drug Metabolism and Disposition January 1993, 21 (1) 7-12;

B

  1. Bai, S A

    1. Effects of propranolol on the disposition and negative dromotropic activity of diltiazem in the dog during multiple dosing.
      C Maskasame, S M Lankford and S A Bai
      Drug Metabolism and Disposition January 1993, 21 (1) 156-161;

  2. Baldew, G S

    1. Reduction of cisplatin nephrotoxicity by sodium selenite. Lack of interaction at the pharmacokinetic level of both compounds.
      N P Vermeulen, G S Baldew, G Los, J G McVie and J J De Goeij
      Drug Metabolism and Disposition January 1993, 21 (1) 30-36;

  3. Battaglia, R

    1. In vivo glucuronidation in rat and humans of 5,6-dihydro-7-(1H-imidazol-1-yl)-naphthalene-2-carboxylic acid, a selective inhibitor of thromboxane synthase.
      J Thomassin, R Battaglia, C Allievi, M G Castelli and M Strolin Benedetti
      Drug Metabolism and Disposition January 1993, 21 (1) 151-155;

  4. Bienvenu, T

    1. Caffeine metabolism in liver slices during postnatal development in rats.
      T Bienvenu, G Pons, E Rey, G Thiroux and G Olive
      Drug Metabolism and Disposition January 1993, 21 (1) 178-180;

  5. Birch, G M

    1. Biotransformation of the antiviral agent 1,3,4-thiadiazol-2-ylcyanamide (LY217896) and characteristics of a mesoionic ribose metabolite.
      W J Ehlhardt, W J Wheeler, A P Breau, S H Chay and G M Birch
      Drug Metabolism and Disposition January 1993, 21 (1) 162-170;

  6. Breau, A P

    1. Biotransformation of the antiviral agent 1,3,4-thiadiazol-2-ylcyanamide (LY217896) and characteristics of a mesoionic ribose metabolite.
      W J Ehlhardt, W J Wheeler, A P Breau, S H Chay and G M Birch
      Drug Metabolism and Disposition January 1993, 21 (1) 162-170;

  7. Burchell, B

    1. Substrate specificities of two stably expressed human liver UDP-glucuronosyltransferases of the UGT1 gene family.
      T Ebner and B Burchell
      Drug Metabolism and Disposition January 1993, 21 (1) 50-55;

C

  1. Canali, S

    1. Pharmacokinetics of recombinant human follicle stimulating hormone after intravenous, intramuscular, and subcutaneous administration in monkeys, and comparison with intravenous administration of urinary follicle stimulating hormone.
      H C Porchet, J Y Le Cotonnec, S Canali and G Zanolo
      Drug Metabolism and Disposition January 1993, 21 (1) 144-150;

  2. Castelli, M G

    1. In vivo glucuronidation in rat and humans of 5,6-dihydro-7-(1H-imidazol-1-yl)-naphthalene-2-carboxylic acid, a selective inhibitor of thromboxane synthase.
      J Thomassin, R Battaglia, C Allievi, M G Castelli and M Strolin Benedetti
      Drug Metabolism and Disposition January 1993, 21 (1) 151-155;

  3. Championsmith, A

    1. Altered pharmacokinetics of recombinant human deoxyribonuclease in rats due to the presence of a binding protein.
      M Mohler, J Cook, D Lewis, J Moore, D Sinicropi, A Championsmith, B Ferraiolo and J Mordenti
      Drug Metabolism and Disposition January 1993, 21 (1) 71-75;

  4. Chan, T M

    1. Identification of two novel indolic metabolites of (R),(R)-labetalol in monkey urine.
      K B Alton, T M Chan and B Pramanik
      Drug Metabolism and Disposition January 1993, 21 (1) 198-199;

  5. Chang, A S

    1. A pharmacokinetic study of phenylcyclohexyldiethylamine. An analog of phencyclidine.
      A K Cho, M Hiramatsu, D A Schmitz, E M Landaw, A S Chang, S Ramamurthy and D J Jenden
      Drug Metabolism and Disposition January 1993, 21 (1) 125-132;

  6. Chay, S H

    1. Biotransformation of the antiviral agent 1,3,4-thiadiazol-2-ylcyanamide (LY217896) and characteristics of a mesoionic ribose metabolite.
      W J Ehlhardt, W J Wheeler, A P Breau, S H Chay and G M Birch
      Drug Metabolism and Disposition January 1993, 21 (1) 162-170;

  7. Chenery, R J

    1. Evidence that famciclovir (BRL 42810) and its associated metabolites do not inhibit the 6 beta-hydroxylation of testosterone in human liver microsomes.
      A W Harrell, S M Wheeler, M Pennick, S E Clarke and R J Chenery
      Drug Metabolism and Disposition January 1993, 21 (1) 18-23;

  8. Cheng, X

    1. A simplified methodology for quantitation of butadiene metabolites. Application to the study of 1,3-butadiene metabolism by rat liver microsomes.
      X Cheng and J A Ruth
      Drug Metabolism and Disposition January 1993, 21 (1) 121-124;

  9. Cho, A K

    1. A pharmacokinetic study of phenylcyclohexyldiethylamine. An analog of phencyclidine.
      A K Cho, M Hiramatsu, D A Schmitz, E M Landaw, A S Chang, S Ramamurthy and D J Jenden
      Drug Metabolism and Disposition January 1993, 21 (1) 125-132;

  10. Clarke, S E

    1. Evidence that famciclovir (BRL 42810) and its associated metabolites do not inhibit the 6 beta-hydroxylation of testosterone in human liver microsomes.
      A W Harrell, S M Wheeler, M Pennick, S E Clarke and R J Chenery
      Drug Metabolism and Disposition January 1993, 21 (1) 18-23;

  11. Clement, B

    1. Oxidation of desmethylpromethazine catalyzed by pig liver flavin-containing monooxygenase. Number and nature of metabolites.
      B Clement, K L Lustig and D M Ziegler
      Drug Metabolism and Disposition January 1993, 21 (1) 24-29;

  12. Colby, H D

    1. Zonal differences in the thermal lability of adrenal microsomal monooxygenases.
      H D Colby, M Levitt and I W Larson
      Drug Metabolism and Disposition January 1993, 21 (1) 200-202;

  13. Cook, J

    1. Altered pharmacokinetics of recombinant human deoxyribonuclease in rats due to the presence of a binding protein.
      M Mohler, J Cook, D Lewis, J Moore, D Sinicropi, A Championsmith, B Ferraiolo and J Mordenti
      Drug Metabolism and Disposition January 1993, 21 (1) 71-75;

D

  1. Daley-Yates, P T

    1. Clearance and tissue uptake following 4-hour and 24-hour infusions of pamidronate in rats.
      M Pongchaidecha and P T Daley-Yates
      Drug Metabolism and Disposition January 1993, 21 (1) 100-104;

  2. Das, M

    1. Biometabolic elimination and organ retention profile of argemone alkaloid, sanguinarine, in rats and guinea pigs.
      S Tandon, M Das and S K Khanna
      Drug Metabolism and Disposition January 1993, 21 (1) 194-197;

  3. Déchelotte, P

    1. Uptake, 3-, and 6-glucuronidation of morphine in isolated cells from stomach, intestine, colon, and liver of the guinea pig.
      P Déchelotte, A Sabouraud, P Sandouk, I Hackbarth and M Schwenk
      Drug Metabolism and Disposition January 1993, 21 (1) 13-17;

  4. De Goeij, J J

    1. Reduction of cisplatin nephrotoxicity by sodium selenite. Lack of interaction at the pharmacokinetic level of both compounds.
      N P Vermeulen, G S Baldew, G Los, J G McVie and J J De Goeij
      Drug Metabolism and Disposition January 1993, 21 (1) 30-36;

  5. du Souich, P

    1. In vivo and in vitro effect of cimetidine, inflammation, and hypoxia on propofol kinetics.
      G Audibert, C G Saunier and P du Souich
      Drug Metabolism and Disposition January 1993, 21 (1) 7-12;

E

  1. Ebner, T

    1. Substrate specificities of two stably expressed human liver UDP-glucuronosyltransferases of the UGT1 gene family.
      T Ebner and B Burchell
      Drug Metabolism and Disposition January 1993, 21 (1) 50-55;

  2. Edwall, B

    1. Disposition of oral [14C]cefcanel daloxate hydrochloride in healthy male subjects.
      B Edwall, A Arvidsson, D Lake-Bakaar, K Lanbeck-Vallén and W Yisak
      Drug Metabolism and Disposition January 1993, 21 (1) 171-177;

  3. Ehlhardt, W J

    1. Biotransformation of the antiviral agent 1,3,4-thiadiazol-2-ylcyanamide (LY217896) and characteristics of a mesoionic ribose metabolite.
      W J Ehlhardt, W J Wheeler, A P Breau, S H Chay and G M Birch
      Drug Metabolism and Disposition January 1993, 21 (1) 162-170;

  4. Eugster, H P

    1. Caffeine, estradiol, and progesterone interact with human CYP1A1 and CYP1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae.
      H P Eugster, M Probst, F E Würgler and C Sengstag
      Drug Metabolism and Disposition January 1993, 21 (1) 43-49;

F

  1. Ferraiolo, B

    1. Altered pharmacokinetics of recombinant human deoxyribonuclease in rats due to the presence of a binding protein.
      M Mohler, J Cook, D Lewis, J Moore, D Sinicropi, A Championsmith, B Ferraiolo and J Mordenti
      Drug Metabolism and Disposition January 1993, 21 (1) 71-75;

G

  1. Gerig, J T

    1. Fluorine NMR studies of the metabolism of flumecinol (3-trifluoromethyl-alpha-ethylbenzhydrol).
      L A Sylvia and J T Gerig
      Drug Metabolism and Disposition January 1993, 21 (1) 105-113;

  2. Godeneche, D

    1. Main urinary metabolites of two cysteamine-containing 2-(chloroethyl) nitrosoureas in rats.
      D Godeneche, P Labarre, M F Moreau, J C Madelmont, M Rapp, J Papon and A Veyre
      Drug Metabolism and Disposition January 1993, 21 (1) 93-99;

  3. Goehl, T J

    1. Zidovudine bioavailability and linear pharmacokinetics in female B6C3F1 mice.
      J M Trang, J D Prejean, R H James, R D Irwin, T J Goehl and J G Page
      Drug Metabolism and Disposition January 1993, 21 (1) 189-193;

  4. Guengerich, F P

    1. The 1992 Bernard B. Brodie Award Lecture. Bioactivation and detoxication of toxic and carcinogenic chemicals.
      F P Guengerich
      Drug Metabolism and Disposition January 1993, 21 (1) 1-6;

H

  1. Hackbarth, I

    1. Uptake, 3-, and 6-glucuronidation of morphine in isolated cells from stomach, intestine, colon, and liver of the guinea pig.
      P Déchelotte, A Sabouraud, P Sandouk, I Hackbarth and M Schwenk
      Drug Metabolism and Disposition January 1993, 21 (1) 13-17;

  2. Hall, S D

    1. Metabolic inversion of (R)-ibuprofen. Formation of ibuprofenyl-coenzyme A.
      T S Tracy, D P Wirthwein and S D Hall
      Drug Metabolism and Disposition January 1993, 21 (1) 114-120;

  3. Hall, T W

    1. Metabolism of N,N-diethylbenzamide and N,N-diethyl-alpha,alpha'-13C-benzamide by rat liver microsomes.
      W G Taylor, T W Hall and D D Vedres
      Drug Metabolism and Disposition January 1993, 21 (1) 133-140;

  4. Harrell, A W

    1. Evidence that famciclovir (BRL 42810) and its associated metabolites do not inhibit the 6 beta-hydroxylation of testosterone in human liver microsomes.
      A W Harrell, S M Wheeler, M Pennick, S E Clarke and R J Chenery
      Drug Metabolism and Disposition January 1993, 21 (1) 18-23;

  5. Hinton, M L

    1. Pharmacokinetics and disposition in the rat of a DNA intercalator 502U83.
      D K Patel, R P Lewis, M L Hinton, D H Schroeder, J P Shockcor, R L Johnson and C W Sigel
      Drug Metabolism and Disposition January 1993, 21 (1) 62-70;

  6. Hiramatsu, M

    1. A pharmacokinetic study of phenylcyclohexyldiethylamine. An analog of phencyclidine.
      A K Cho, M Hiramatsu, D A Schmitz, E M Landaw, A S Chang, S Ramamurthy and D J Jenden
      Drug Metabolism and Disposition January 1993, 21 (1) 125-132;

I

  1. Irwin, R D

    1. Zidovudine bioavailability and linear pharmacokinetics in female B6C3F1 mice.
      J M Trang, J D Prejean, R H James, R D Irwin, T J Goehl and J G Page
      Drug Metabolism and Disposition January 1993, 21 (1) 189-193;

  2. Iwakawa, S

    1. Effect of atropine on gastrointestinal motility and the bioavailability of cyclosporine A in rats.
      R F Quijano, N Ohnishi, K Umeda, F Komada, S Iwakawa and K Okumura
      Drug Metabolism and Disposition January 1993, 21 (1) 141-143;

J

  1. James, R H

    1. Zidovudine bioavailability and linear pharmacokinetics in female B6C3F1 mice.
      J M Trang, J D Prejean, R H James, R D Irwin, T J Goehl and J G Page
      Drug Metabolism and Disposition January 1993, 21 (1) 189-193;

  2. Jenden, D J

    1. A pharmacokinetic study of phenylcyclohexyldiethylamine. An analog of phencyclidine.
      A K Cho, M Hiramatsu, D A Schmitz, E M Landaw, A S Chang, S Ramamurthy and D J Jenden
      Drug Metabolism and Disposition January 1993, 21 (1) 125-132;

  3. Johnson, R L

    1. Pharmacokinetics and disposition in the rat of a DNA intercalator 502U83.
      D K Patel, R P Lewis, M L Hinton, D H Schroeder, J P Shockcor, R L Johnson and C W Sigel
      Drug Metabolism and Disposition January 1993, 21 (1) 62-70;

K

  1. Kanekal, S

    1. Evidence for peroxidase-mediated metabolism of cyclophosphamide.
      S Kanekal and J P Kehrer
      Drug Metabolism and Disposition January 1993, 21 (1) 37-42;

  2. Kehrer, J P

    1. Evidence for peroxidase-mediated metabolism of cyclophosphamide.
      S Kanekal and J P Kehrer
      Drug Metabolism and Disposition January 1993, 21 (1) 37-42;

  3. Khanna, S K

    1. Biometabolic elimination and organ retention profile of argemone alkaloid, sanguinarine, in rats and guinea pigs.
      S Tandon, M Das and S K Khanna
      Drug Metabolism and Disposition January 1993, 21 (1) 194-197;

  4. Komada, F

    1. Effect of atropine on gastrointestinal motility and the bioavailability of cyclosporine A in rats.
      R F Quijano, N Ohnishi, K Umeda, F Komada, S Iwakawa and K Okumura
      Drug Metabolism and Disposition January 1993, 21 (1) 141-143;

L

  1. Labarre, P

    1. Main urinary metabolites of two cysteamine-containing 2-(chloroethyl) nitrosoureas in rats.
      D Godeneche, P Labarre, M F Moreau, J C Madelmont, M Rapp, J Papon and A Veyre
      Drug Metabolism and Disposition January 1993, 21 (1) 93-99;

  2. Lake-Bakaar, D

    1. Disposition of oral [14C]cefcanel daloxate hydrochloride in healthy male subjects.
      B Edwall, A Arvidsson, D Lake-Bakaar, K Lanbeck-Vallén and W Yisak
      Drug Metabolism and Disposition January 1993, 21 (1) 171-177;

  3. Lanbeck-Vallén, K

    1. Disposition of oral [14C]cefcanel daloxate hydrochloride in healthy male subjects.
      B Edwall, A Arvidsson, D Lake-Bakaar, K Lanbeck-Vallén and W Yisak
      Drug Metabolism and Disposition January 1993, 21 (1) 171-177;

  4. Landaw, E M

    1. A pharmacokinetic study of phenylcyclohexyldiethylamine. An analog of phencyclidine.
      A K Cho, M Hiramatsu, D A Schmitz, E M Landaw, A S Chang, S Ramamurthy and D J Jenden
      Drug Metabolism and Disposition January 1993, 21 (1) 125-132;

  5. Lankford, S M

    1. Effects of propranolol on the disposition and negative dromotropic activity of diltiazem in the dog during multiple dosing.
      C Maskasame, S M Lankford and S A Bai
      Drug Metabolism and Disposition January 1993, 21 (1) 156-161;

  6. Larson, I W

    1. Zonal differences in the thermal lability of adrenal microsomal monooxygenases.
      H D Colby, M Levitt and I W Larson
      Drug Metabolism and Disposition January 1993, 21 (1) 200-202;

  7. Le Cotonnec, J Y

    1. Pharmacokinetics of recombinant human follicle stimulating hormone after intravenous, intramuscular, and subcutaneous administration in monkeys, and comparison with intravenous administration of urinary follicle stimulating hormone.
      H C Porchet, J Y Le Cotonnec, S Canali and G Zanolo
      Drug Metabolism and Disposition January 1993, 21 (1) 144-150;

  8. Levitt, M

    1. Zonal differences in the thermal lability of adrenal microsomal monooxygenases.
      H D Colby, M Levitt and I W Larson
      Drug Metabolism and Disposition January 1993, 21 (1) 200-202;

  9. Lewis, D

    1. Altered pharmacokinetics of recombinant human deoxyribonuclease in rats due to the presence of a binding protein.
      M Mohler, J Cook, D Lewis, J Moore, D Sinicropi, A Championsmith, B Ferraiolo and J Mordenti
      Drug Metabolism and Disposition January 1993, 21 (1) 71-75;

  10. Lewis, R P

    1. Pharmacokinetics and disposition in the rat of a DNA intercalator 502U83.
      D K Patel, R P Lewis, M L Hinton, D H Schroeder, J P Shockcor, R L Johnson and C W Sigel
      Drug Metabolism and Disposition January 1993, 21 (1) 62-70;

  11. Lipa, J

    1. Inducibility of enzyme activities associated with the cytochrome P-450 1A family, ethoxyresorufin O-deethylase, and methoxyresorufin O-demethylase in human hepatocyte lines derived from normal liver tissue.
      E A Roberts, Z W Xie, S Yang and J Lipa
      Drug Metabolism and Disposition January 1993, 21 (1) 56-61;

  12. Los, G

    1. Reduction of cisplatin nephrotoxicity by sodium selenite. Lack of interaction at the pharmacokinetic level of both compounds.
      N P Vermeulen, G S Baldew, G Los, J G McVie and J J De Goeij
      Drug Metabolism and Disposition January 1993, 21 (1) 30-36;

  13. Lustig, K L

    1. Oxidation of desmethylpromethazine catalyzed by pig liver flavin-containing monooxygenase. Number and nature of metabolites.
      B Clement, K L Lustig and D M Ziegler
      Drug Metabolism and Disposition January 1993, 21 (1) 24-29;

M

  1. Madelmont, J C

    1. Main urinary metabolites of two cysteamine-containing 2-(chloroethyl) nitrosoureas in rats.
      D Godeneche, P Labarre, M F Moreau, J C Madelmont, M Rapp, J Papon and A Veyre
      Drug Metabolism and Disposition January 1993, 21 (1) 93-99;

  2. Manis, M

    1. Inhibition of human red blood cell N-acetyltransferase.
      R A Voice, M Manis and W W Weber
      Drug Metabolism and Disposition January 1993, 21 (1) 181-183;

  3. Maskasame, C

    1. Effects of propranolol on the disposition and negative dromotropic activity of diltiazem in the dog during multiple dosing.
      C Maskasame, S M Lankford and S A Bai
      Drug Metabolism and Disposition January 1993, 21 (1) 156-161;

  4. McVie, J G

    1. Reduction of cisplatin nephrotoxicity by sodium selenite. Lack of interaction at the pharmacokinetic level of both compounds.
      N P Vermeulen, G S Baldew, G Los, J G McVie and J J De Goeij
      Drug Metabolism and Disposition January 1993, 21 (1) 30-36;

  5. Mohler, M

    1. Altered pharmacokinetics of recombinant human deoxyribonuclease in rats due to the presence of a binding protein.
      M Mohler, J Cook, D Lewis, J Moore, D Sinicropi, A Championsmith, B Ferraiolo and J Mordenti
      Drug Metabolism and Disposition January 1993, 21 (1) 71-75;

  6. Moore, J

    1. Altered pharmacokinetics of recombinant human deoxyribonuclease in rats due to the presence of a binding protein.
      M Mohler, J Cook, D Lewis, J Moore, D Sinicropi, A Championsmith, B Ferraiolo and J Mordenti
      Drug Metabolism and Disposition January 1993, 21 (1) 71-75;

  7. Mordenti, J

    1. Altered pharmacokinetics of recombinant human deoxyribonuclease in rats due to the presence of a binding protein.
      M Mohler, J Cook, D Lewis, J Moore, D Sinicropi, A Championsmith, B Ferraiolo and J Mordenti
      Drug Metabolism and Disposition January 1993, 21 (1) 71-75;

  8. Moreau, M F

    1. Main urinary metabolites of two cysteamine-containing 2-(chloroethyl) nitrosoureas in rats.
      D Godeneche, P Labarre, M F Moreau, J C Madelmont, M Rapp, J Papon and A Veyre
      Drug Metabolism and Disposition January 1993, 21 (1) 93-99;

O

  1. Ohnishi, N

    1. Effect of atropine on gastrointestinal motility and the bioavailability of cyclosporine A in rats.
      R F Quijano, N Ohnishi, K Umeda, F Komada, S Iwakawa and K Okumura
      Drug Metabolism and Disposition January 1993, 21 (1) 141-143;

  2. Okumura, K

    1. Effect of atropine on gastrointestinal motility and the bioavailability of cyclosporine A in rats.
      R F Quijano, N Ohnishi, K Umeda, F Komada, S Iwakawa and K Okumura
      Drug Metabolism and Disposition January 1993, 21 (1) 141-143;

  3. Olive, G

    1. Caffeine metabolism in liver slices during postnatal development in rats.
      T Bienvenu, G Pons, E Rey, G Thiroux and G Olive
      Drug Metabolism and Disposition January 1993, 21 (1) 178-180;

  4. Ottoila, P

    1. Identification of major metabolites of the catechol-O-methyltransferase inhibitor entacapone in rats and humans.
      T Wikberg, A Vuorela, P Ottoila and J Taskinen
      Drug Metabolism and Disposition January 1993, 21 (1) 81-92;

P

  1. Page, J G

    1. Zidovudine bioavailability and linear pharmacokinetics in female B6C3F1 mice.
      J M Trang, J D Prejean, R H James, R D Irwin, T J Goehl and J G Page
      Drug Metabolism and Disposition January 1993, 21 (1) 189-193;

  2. Papon, J

    1. Main urinary metabolites of two cysteamine-containing 2-(chloroethyl) nitrosoureas in rats.
      D Godeneche, P Labarre, M F Moreau, J C Madelmont, M Rapp, J Papon and A Veyre
      Drug Metabolism and Disposition January 1993, 21 (1) 93-99;

  3. Patel, D K

    1. Pharmacokinetics and disposition in the rat of a DNA intercalator 502U83.
      D K Patel, R P Lewis, M L Hinton, D H Schroeder, J P Shockcor, R L Johnson and C W Sigel
      Drug Metabolism and Disposition January 1993, 21 (1) 62-70;

  4. Pennick, M

    1. Evidence that famciclovir (BRL 42810) and its associated metabolites do not inhibit the 6 beta-hydroxylation of testosterone in human liver microsomes.
      A W Harrell, S M Wheeler, M Pennick, S E Clarke and R J Chenery
      Drug Metabolism and Disposition January 1993, 21 (1) 18-23;

  5. Perry, P R

    1. Hepatic elimination in the rat of ditekiren (U-71038), a renin inhibitor pseudohexapeptide.
      A Adedoyin, P R Perry and G R Wilkinson
      Drug Metabolism and Disposition January 1993, 21 (1) 184-188;

  6. Pongchaidecha, M

    1. Clearance and tissue uptake following 4-hour and 24-hour infusions of pamidronate in rats.
      M Pongchaidecha and P T Daley-Yates
      Drug Metabolism and Disposition January 1993, 21 (1) 100-104;

  7. Pons, G

    1. Caffeine metabolism in liver slices during postnatal development in rats.
      T Bienvenu, G Pons, E Rey, G Thiroux and G Olive
      Drug Metabolism and Disposition January 1993, 21 (1) 178-180;

  8. Porchet, H C

    1. Pharmacokinetics of recombinant human follicle stimulating hormone after intravenous, intramuscular, and subcutaneous administration in monkeys, and comparison with intravenous administration of urinary follicle stimulating hormone.
      H C Porchet, J Y Le Cotonnec, S Canali and G Zanolo
      Drug Metabolism and Disposition January 1993, 21 (1) 144-150;

  9. Pramanik, B

    1. Identification of two novel indolic metabolites of (R),(R)-labetalol in monkey urine.
      K B Alton, T M Chan and B Pramanik
      Drug Metabolism and Disposition January 1993, 21 (1) 198-199;

  10. Prejean, J D

    1. Zidovudine bioavailability and linear pharmacokinetics in female B6C3F1 mice.
      J M Trang, J D Prejean, R H James, R D Irwin, T J Goehl and J G Page
      Drug Metabolism and Disposition January 1993, 21 (1) 189-193;

  11. Probst, M

    1. Caffeine, estradiol, and progesterone interact with human CYP1A1 and CYP1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae.
      H P Eugster, M Probst, F E Würgler and C Sengstag
      Drug Metabolism and Disposition January 1993, 21 (1) 43-49;

Q

  1. Quijano, R F

    1. Effect of atropine on gastrointestinal motility and the bioavailability of cyclosporine A in rats.
      R F Quijano, N Ohnishi, K Umeda, F Komada, S Iwakawa and K Okumura
      Drug Metabolism and Disposition January 1993, 21 (1) 141-143;

R

  1. Ramamurthy, S

    1. A pharmacokinetic study of phenylcyclohexyldiethylamine. An analog of phencyclidine.
      A K Cho, M Hiramatsu, D A Schmitz, E M Landaw, A S Chang, S Ramamurthy and D J Jenden
      Drug Metabolism and Disposition January 1993, 21 (1) 125-132;

  2. Rapp, M

    1. Main urinary metabolites of two cysteamine-containing 2-(chloroethyl) nitrosoureas in rats.
      D Godeneche, P Labarre, M F Moreau, J C Madelmont, M Rapp, J Papon and A Veyre
      Drug Metabolism and Disposition January 1993, 21 (1) 93-99;

  3. Rey, E

    1. Caffeine metabolism in liver slices during postnatal development in rats.
      T Bienvenu, G Pons, E Rey, G Thiroux and G Olive
      Drug Metabolism and Disposition January 1993, 21 (1) 178-180;

  4. Roberts, E A

    1. Inducibility of enzyme activities associated with the cytochrome P-450 1A family, ethoxyresorufin O-deethylase, and methoxyresorufin O-demethylase in human hepatocyte lines derived from normal liver tissue.
      E A Roberts, Z W Xie, S Yang and J Lipa
      Drug Metabolism and Disposition January 1993, 21 (1) 56-61;

  5. Ruth, J A

    1. A simplified methodology for quantitation of butadiene metabolites. Application to the study of 1,3-butadiene metabolism by rat liver microsomes.
      X Cheng and J A Ruth
      Drug Metabolism and Disposition January 1993, 21 (1) 121-124;

S

  1. Sabouraud, A

    1. Uptake, 3-, and 6-glucuronidation of morphine in isolated cells from stomach, intestine, colon, and liver of the guinea pig.
      P Déchelotte, A Sabouraud, P Sandouk, I Hackbarth and M Schwenk
      Drug Metabolism and Disposition January 1993, 21 (1) 13-17;

  2. Sandouk, P

    1. Uptake, 3-, and 6-glucuronidation of morphine in isolated cells from stomach, intestine, colon, and liver of the guinea pig.
      P Déchelotte, A Sabouraud, P Sandouk, I Hackbarth and M Schwenk
      Drug Metabolism and Disposition January 1993, 21 (1) 13-17;

  3. Saunier, C G

    1. In vivo and in vitro effect of cimetidine, inflammation, and hypoxia on propofol kinetics.
      G Audibert, C G Saunier and P du Souich
      Drug Metabolism and Disposition January 1993, 21 (1) 7-12;

  4. Schey, K L

    1. Stereoselective sulfation of albuterol in humans. Biosynthesis of the sulfate conjugate by HEP G2 cells.
      T Walle, U K Walle, K R Thornburg and K L Schey
      Drug Metabolism and Disposition January 1993, 21 (1) 76-80;

  5. Schmitz, D A

    1. A pharmacokinetic study of phenylcyclohexyldiethylamine. An analog of phencyclidine.
      A K Cho, M Hiramatsu, D A Schmitz, E M Landaw, A S Chang, S Ramamurthy and D J Jenden
      Drug Metabolism and Disposition January 1993, 21 (1) 125-132;

  6. Schroeder, D H

    1. Pharmacokinetics and disposition in the rat of a DNA intercalator 502U83.
      D K Patel, R P Lewis, M L Hinton, D H Schroeder, J P Shockcor, R L Johnson and C W Sigel
      Drug Metabolism and Disposition January 1993, 21 (1) 62-70;

  7. Schwenk, M

    1. Uptake, 3-, and 6-glucuronidation of morphine in isolated cells from stomach, intestine, colon, and liver of the guinea pig.
      P Déchelotte, A Sabouraud, P Sandouk, I Hackbarth and M Schwenk
      Drug Metabolism and Disposition January 1993, 21 (1) 13-17;

  8. Sengstag, C

    1. Caffeine, estradiol, and progesterone interact with human CYP1A1 and CYP1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae.
      H P Eugster, M Probst, F E Würgler and C Sengstag
      Drug Metabolism and Disposition January 1993, 21 (1) 43-49;

  9. Shockcor, J P

    1. Pharmacokinetics and disposition in the rat of a DNA intercalator 502U83.
      D K Patel, R P Lewis, M L Hinton, D H Schroeder, J P Shockcor, R L Johnson and C W Sigel
      Drug Metabolism and Disposition January 1993, 21 (1) 62-70;

  10. Sigel, C W

    1. Pharmacokinetics and disposition in the rat of a DNA intercalator 502U83.
      D K Patel, R P Lewis, M L Hinton, D H Schroeder, J P Shockcor, R L Johnson and C W Sigel
      Drug Metabolism and Disposition January 1993, 21 (1) 62-70;

  11. Sinicropi, D

    1. Altered pharmacokinetics of recombinant human deoxyribonuclease in rats due to the presence of a binding protein.
      M Mohler, J Cook, D Lewis, J Moore, D Sinicropi, A Championsmith, B Ferraiolo and J Mordenti
      Drug Metabolism and Disposition January 1993, 21 (1) 71-75;

  12. Strolin Benedetti, M

    1. In vivo glucuronidation in rat and humans of 5,6-dihydro-7-(1H-imidazol-1-yl)-naphthalene-2-carboxylic acid, a selective inhibitor of thromboxane synthase.
      J Thomassin, R Battaglia, C Allievi, M G Castelli and M Strolin Benedetti
      Drug Metabolism and Disposition January 1993, 21 (1) 151-155;

  13. Sylvia, L A

    1. Fluorine NMR studies of the metabolism of flumecinol (3-trifluoromethyl-alpha-ethylbenzhydrol).
      L A Sylvia and J T Gerig
      Drug Metabolism and Disposition January 1993, 21 (1) 105-113;

T

  1. Tandon, S

    1. Biometabolic elimination and organ retention profile of argemone alkaloid, sanguinarine, in rats and guinea pigs.
      S Tandon, M Das and S K Khanna
      Drug Metabolism and Disposition January 1993, 21 (1) 194-197;

  2. Taskinen, J

    1. Identification of major metabolites of the catechol-O-methyltransferase inhibitor entacapone in rats and humans.
      T Wikberg, A Vuorela, P Ottoila and J Taskinen
      Drug Metabolism and Disposition January 1993, 21 (1) 81-92;

  3. Taylor, W G

    1. Metabolism of N,N-diethylbenzamide and N,N-diethyl-alpha,alpha'-13C-benzamide by rat liver microsomes.
      W G Taylor, T W Hall and D D Vedres
      Drug Metabolism and Disposition January 1993, 21 (1) 133-140;

  4. Thiroux, G

    1. Caffeine metabolism in liver slices during postnatal development in rats.
      T Bienvenu, G Pons, E Rey, G Thiroux and G Olive
      Drug Metabolism and Disposition January 1993, 21 (1) 178-180;

  5. Thomassin, J

    1. In vivo glucuronidation in rat and humans of 5,6-dihydro-7-(1H-imidazol-1-yl)-naphthalene-2-carboxylic acid, a selective inhibitor of thromboxane synthase.
      J Thomassin, R Battaglia, C Allievi, M G Castelli and M Strolin Benedetti
      Drug Metabolism and Disposition January 1993, 21 (1) 151-155;

  6. Thornburg, K R

    1. Stereoselective sulfation of albuterol in humans. Biosynthesis of the sulfate conjugate by HEP G2 cells.
      T Walle, U K Walle, K R Thornburg and K L Schey
      Drug Metabolism and Disposition January 1993, 21 (1) 76-80;

  7. Tracy, T S

    1. Metabolic inversion of (R)-ibuprofen. Formation of ibuprofenyl-coenzyme A.
      T S Tracy, D P Wirthwein and S D Hall
      Drug Metabolism and Disposition January 1993, 21 (1) 114-120;

  8. Trang, J M

    1. Zidovudine bioavailability and linear pharmacokinetics in female B6C3F1 mice.
      J M Trang, J D Prejean, R H James, R D Irwin, T J Goehl and J G Page
      Drug Metabolism and Disposition January 1993, 21 (1) 189-193;

U

  1. Umeda, K

    1. Effect of atropine on gastrointestinal motility and the bioavailability of cyclosporine A in rats.
      R F Quijano, N Ohnishi, K Umeda, F Komada, S Iwakawa and K Okumura
      Drug Metabolism and Disposition January 1993, 21 (1) 141-143;

V

  1. Vedres, D D

    1. Metabolism of N,N-diethylbenzamide and N,N-diethyl-alpha,alpha'-13C-benzamide by rat liver microsomes.
      W G Taylor, T W Hall and D D Vedres
      Drug Metabolism and Disposition January 1993, 21 (1) 133-140;

  2. Vermeulen, N P

    1. Reduction of cisplatin nephrotoxicity by sodium selenite. Lack of interaction at the pharmacokinetic level of both compounds.
      N P Vermeulen, G S Baldew, G Los, J G McVie and J J De Goeij
      Drug Metabolism and Disposition January 1993, 21 (1) 30-36;

  3. Veyre, A

    1. Main urinary metabolites of two cysteamine-containing 2-(chloroethyl) nitrosoureas in rats.
      D Godeneche, P Labarre, M F Moreau, J C Madelmont, M Rapp, J Papon and A Veyre
      Drug Metabolism and Disposition January 1993, 21 (1) 93-99;

  4. Voice, R A

    1. Inhibition of human red blood cell N-acetyltransferase.
      R A Voice, M Manis and W W Weber
      Drug Metabolism and Disposition January 1993, 21 (1) 181-183;

  5. Vuorela, A

    1. Identification of major metabolites of the catechol-O-methyltransferase inhibitor entacapone in rats and humans.
      T Wikberg, A Vuorela, P Ottoila and J Taskinen
      Drug Metabolism and Disposition January 1993, 21 (1) 81-92;

W

  1. Walle, T

    1. Stereoselective sulfation of albuterol in humans. Biosynthesis of the sulfate conjugate by HEP G2 cells.
      T Walle, U K Walle, K R Thornburg and K L Schey
      Drug Metabolism and Disposition January 1993, 21 (1) 76-80;

  2. Walle, U K

    1. Stereoselective sulfation of albuterol in humans. Biosynthesis of the sulfate conjugate by HEP G2 cells.
      T Walle, U K Walle, K R Thornburg and K L Schey
      Drug Metabolism and Disposition January 1993, 21 (1) 76-80;

  3. Weber, W W

    1. Inhibition of human red blood cell N-acetyltransferase.
      R A Voice, M Manis and W W Weber
      Drug Metabolism and Disposition January 1993, 21 (1) 181-183;

  4. Wheeler, S M

    1. Evidence that famciclovir (BRL 42810) and its associated metabolites do not inhibit the 6 beta-hydroxylation of testosterone in human liver microsomes.
      A W Harrell, S M Wheeler, M Pennick, S E Clarke and R J Chenery
      Drug Metabolism and Disposition January 1993, 21 (1) 18-23;

  5. Wheeler, W J

    1. Biotransformation of the antiviral agent 1,3,4-thiadiazol-2-ylcyanamide (LY217896) and characteristics of a mesoionic ribose metabolite.
      W J Ehlhardt, W J Wheeler, A P Breau, S H Chay and G M Birch
      Drug Metabolism and Disposition January 1993, 21 (1) 162-170;

  6. Wikberg, T

    1. Identification of major metabolites of the catechol-O-methyltransferase inhibitor entacapone in rats and humans.
      T Wikberg, A Vuorela, P Ottoila and J Taskinen
      Drug Metabolism and Disposition January 1993, 21 (1) 81-92;

  7. Wilkinson, G R

    1. Hepatic elimination in the rat of ditekiren (U-71038), a renin inhibitor pseudohexapeptide.
      A Adedoyin, P R Perry and G R Wilkinson
      Drug Metabolism and Disposition January 1993, 21 (1) 184-188;

  8. Wirthwein, D P

    1. Metabolic inversion of (R)-ibuprofen. Formation of ibuprofenyl-coenzyme A.
      T S Tracy, D P Wirthwein and S D Hall
      Drug Metabolism and Disposition January 1993, 21 (1) 114-120;

  9. Würgler, F E

    1. Caffeine, estradiol, and progesterone interact with human CYP1A1 and CYP1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae.
      H P Eugster, M Probst, F E Würgler and C Sengstag
      Drug Metabolism and Disposition January 1993, 21 (1) 43-49;

X

  1. Xie, Z W

    1. Inducibility of enzyme activities associated with the cytochrome P-450 1A family, ethoxyresorufin O-deethylase, and methoxyresorufin O-demethylase in human hepatocyte lines derived from normal liver tissue.
      E A Roberts, Z W Xie, S Yang and J Lipa
      Drug Metabolism and Disposition January 1993, 21 (1) 56-61;

Y

  1. Yang, S

    1. Inducibility of enzyme activities associated with the cytochrome P-450 1A family, ethoxyresorufin O-deethylase, and methoxyresorufin O-demethylase in human hepatocyte lines derived from normal liver tissue.
      E A Roberts, Z W Xie, S Yang and J Lipa
      Drug Metabolism and Disposition January 1993, 21 (1) 56-61;

  2. Yisak, W

    1. Disposition of oral [14C]cefcanel daloxate hydrochloride in healthy male subjects.
      B Edwall, A Arvidsson, D Lake-Bakaar, K Lanbeck-Vallén and W Yisak
      Drug Metabolism and Disposition January 1993, 21 (1) 171-177;

Z

  1. Zanolo, G

    1. Pharmacokinetics of recombinant human follicle stimulating hormone after intravenous, intramuscular, and subcutaneous administration in monkeys, and comparison with intravenous administration of urinary follicle stimulating hormone.
      H C Porchet, J Y Le Cotonnec, S Canali and G Zanolo
      Drug Metabolism and Disposition January 1993, 21 (1) 144-150;

  2. Ziegler, D M

    1. Oxidation of desmethylpromethazine catalyzed by pig liver flavin-containing monooxygenase. Number and nature of metabolites.
      B Clement, K L Lustig and D M Ziegler
      Drug Metabolism and Disposition January 1993, 21 (1) 24-29;
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