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Drug Metabolism & Disposition

Advanced Search

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  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
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Index by author

May 01, 1993; Volume 21,Issue 3
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Abbott, F S

    1. You have access
      Metabolic profiling of clobazam, a 1,5-benzodiazepine, in rats.
      A G Borel and F S Abbott
      Drug Metabolism and Disposition May 1993, 21 (3) 415-427;
  2. Adam, A

    1. You have access
      Hepatic and extrahepatic metabolism of salbutamol in anesthetized rabbits.
      S Perreault, L Dumont, V Villiere, H Ong, A Adam and P du Souich
      Drug Metabolism and Disposition May 1993, 21 (3) 485-491;
  3. Au, J L

    1. You have access
      2',3'-Dideoxyinosine is not metabolized in human placenta.
      J T Dalton and J L Au
      Drug Metabolism and Disposition May 1993, 21 (3) 544-546;

B

  1. Barbhaiya, R H

    1. You have access
      Absorption, disposition, and metabolism of [14C]didanosine in the beagle dog.
      S Kaul, W C Shyu, U A Shukla, K A Dandekar and R H Barbhaiya
      Drug Metabolism and Disposition May 1993, 21 (3) 447-453;
    2. You have access
      Pharmacokinetics, absolute bioavailability, and disposition of [14C]nefazodone in the dog.
      U A Shukla, P H Marathe, K A Pittman and R H Barbhaiya
      Drug Metabolism and Disposition May 1993, 21 (3) 502-507;
  2. Bezek, S

    1. You have access
      Characterization of nonlinear elimination of the xanthine-related drug ethimizol in 3-methylcholanthrene-induced rat liver by the "parallel-tube" model.
      M Kukan, T F Woolf, M Melus and S Bezek
      Drug Metabolism and Disposition May 1993, 21 (3) 547-550;
  3. Biggi, W A

    1. You have access
      The biotransformation of the ergot derivative CQA 206-291 in human, dog, and rat liver slice cultures and prediction of in vivo plasma clearance.
      A E Vickers, S Connors, M Zollinger, W A Biggi, A Larrauri, J P Vogelaar and K Brendel
      Drug Metabolism and Disposition May 1993, 21 (3) 454-459;
  4. Bland, T J

    1. You have access
      Metabolism of the experimental antitumor agent acridine carboxamide in the mouse.
      I G Robertson, B D Palmer, J W Paxton and T J Bland
      Drug Metabolism and Disposition May 1993, 21 (3) 530-536;
  5. Boeren, S

    1. You have access
      Qualitative and quantitative influences of ortho chlorine substituents on the microsomal metabolism of 4-toluidines.
      B Tyrakowska, S Boeren, B Geurtsen and I M Rietjens
      Drug Metabolism and Disposition May 1993, 21 (3) 508-519;
  6. Bongard, R D

    1. You have access
      Influence of temperature and plasma protein on doxorubicin uptake by isolated lungs.
      R D Bongard, D L Roerig, M R Johnston, J H Linehan and C A Dawson
      Drug Metabolism and Disposition May 1993, 21 (3) 428-434;
  7. Borel, A G

    1. You have access
      Metabolic profiling of clobazam, a 1,5-benzodiazepine, in rats.
      A G Borel and F S Abbott
      Drug Metabolism and Disposition May 1993, 21 (3) 415-427;
  8. Brendel, K

    1. You have access
      The biotransformation of the ergot derivative CQA 206-291 in human, dog, and rat liver slice cultures and prediction of in vivo plasma clearance.
      A E Vickers, S Connors, M Zollinger, W A Biggi, A Larrauri, J P Vogelaar and K Brendel
      Drug Metabolism and Disposition May 1993, 21 (3) 454-459;

C

  1. Cashman, J R

    1. You have access
      Stereo- and regioselective N- and S-oxidation of tertiary amines and sulfides in the presence of adult human liver microsomes.
      J R Cashman, Z Yang, L Yang and S A Wrighton
      Drug Metabolism and Disposition May 1993, 21 (3) 492-501;
  2. Chen, T M

    1. You have access
      Pharmacokinetics and metabolism of vigabatrin following a single oral dose of [14C]vigabatrin in healthy male volunteers.
      S L Durham, J F Hoke and T M Chen
      Drug Metabolism and Disposition May 1993, 21 (3) 480-484;
  3. Chikai, T

    1. You have access
      Enantiomer-enantiomer interaction on N-monodemethylation of diuretic in rat liver microsomes.
      M Nakano, T Chikai and T Matsubara
      Drug Metabolism and Disposition May 1993, 21 (3) 542-543;
  4. Connors, S

    1. You have access
      The biotransformation of the ergot derivative CQA 206-291 in human, dog, and rat liver slice cultures and prediction of in vivo plasma clearance.
      A E Vickers, S Connors, M Zollinger, W A Biggi, A Larrauri, J P Vogelaar and K Brendel
      Drug Metabolism and Disposition May 1993, 21 (3) 454-459;
  5. Cribb, A E

    1. You have access
      Modulation of rat hepatic CYP3A1 induction by the interferon inducer polyinosinic acid-polycytidylic acid (polyic).
      E Delaporte, A E Cribb and K W Renton
      Drug Metabolism and Disposition May 1993, 21 (3) 520-523;

D

  1. Dalton, J T

    1. You have access
      2',3'-Dideoxyinosine is not metabolized in human placenta.
      J T Dalton and J L Au
      Drug Metabolism and Disposition May 1993, 21 (3) 544-546;
  2. Dandekar, K A

    1. You have access
      Absorption, disposition, and metabolism of [14C]didanosine in the beagle dog.
      S Kaul, W C Shyu, U A Shukla, K A Dandekar and R H Barbhaiya
      Drug Metabolism and Disposition May 1993, 21 (3) 447-453;
  3. Dawson, C A

    1. You have access
      Influence of temperature and plasma protein on doxorubicin uptake by isolated lungs.
      R D Bongard, D L Roerig, M R Johnston, J H Linehan and C A Dawson
      Drug Metabolism and Disposition May 1993, 21 (3) 428-434;
  4. Day, W W

    1. You have access
      Increased renal drug metabolism in treadmill-exercised Fischer-344 male rats.
      T S Piatkowski, W W Day and M Weiner
      Drug Metabolism and Disposition May 1993, 21 (3) 474-479;
  5. Delaporte, E

    1. You have access
      Modulation of rat hepatic CYP3A1 induction by the interferon inducer polyinosinic acid-polycytidylic acid (polyic).
      E Delaporte, A E Cribb and K W Renton
      Drug Metabolism and Disposition May 1993, 21 (3) 520-523;
  6. Drerup, J M

    1. You have access
      Conditions influencing the rat liver microsomal metabolism of 2,2,-dichloro-1,1,1-trifluoroethane (HCFC-123).
      C S Godin, J M Drerup and A Vinegar
      Drug Metabolism and Disposition May 1993, 21 (3) 551-553;
  7. Dumont, L

    1. You have access
      Hepatic and extrahepatic metabolism of salbutamol in anesthetized rabbits.
      S Perreault, L Dumont, V Villiere, H Ong, A Adam and P du Souich
      Drug Metabolism and Disposition May 1993, 21 (3) 485-491;
  8. Duncan, C A

    1. You have access
      In vivo and in vitro metabolism studies on a class III antiarrhythmic agent.
      S Vickers, C A Duncan, P H Kari, C F Homnick, J M Elliott, S M Pitzenberger, M Hichens and K P Vyas
      Drug Metabolism and Disposition May 1993, 21 (3) 467-473;
  9. Durham, S L

    1. You have access
      Pharmacokinetics and metabolism of vigabatrin following a single oral dose of [14C]vigabatrin in healthy male volunteers.
      S L Durham, J F Hoke and T M Chen
      Drug Metabolism and Disposition May 1993, 21 (3) 480-484;
  10. du Souich, P

    1. You have access
      Hepatic and extrahepatic metabolism of salbutamol in anesthetized rabbits.
      S Perreault, L Dumont, V Villiere, H Ong, A Adam and P du Souich
      Drug Metabolism and Disposition May 1993, 21 (3) 485-491;

E

  1. Elliott, J M

    1. You have access
      In vivo and in vitro metabolism studies on a class III antiarrhythmic agent.
      S Vickers, C A Duncan, P H Kari, C F Homnick, J M Elliott, S M Pitzenberger, M Hichens and K P Vyas
      Drug Metabolism and Disposition May 1993, 21 (3) 467-473;

F

  1. Farooqui, M Y

    1. You have access
      Toxicokinetics of allynitrile in rats.
      M Y Farooqui, B Ybarra and J Piper
      Drug Metabolism and Disposition May 1993, 21 (3) 460-466;

G

  1. Geurtsen, B

    1. You have access
      Qualitative and quantitative influences of ortho chlorine substituents on the microsomal metabolism of 4-toluidines.
      B Tyrakowska, S Boeren, B Geurtsen and I M Rietjens
      Drug Metabolism and Disposition May 1993, 21 (3) 508-519;
  2. Godin, C S

    1. You have access
      Conditions influencing the rat liver microsomal metabolism of 2,2,-dichloro-1,1,1-trifluoroethane (HCFC-123).
      C S Godin, J M Drerup and A Vinegar
      Drug Metabolism and Disposition May 1993, 21 (3) 551-553;
  3. Guengerich, F P

    1. You have access
      Oxidation of the antihistaminic drug terfenadine in human liver microsomes. Role of cytochrome P-450 3A(4) in N-dealkylation and C-hydroxylation.
      C H Yun, R A Okerholm and F P Guengerich
      Drug Metabolism and Disposition May 1993, 21 (3) 403-409;

H

  1. Harbison, R D

    1. You have access
      Inhibition by ethanol of the metabolism of cocaine to benzoylecgonine and ecgonine methyl ester in mouse and human liver.
      S M Roberts, R D Harbison and R C James
      Drug Metabolism and Disposition May 1993, 21 (3) 537-541;
  2. Hichens, M

    1. You have access
      In vivo and in vitro metabolism studies on a class III antiarrhythmic agent.
      S Vickers, C A Duncan, P H Kari, C F Homnick, J M Elliott, S M Pitzenberger, M Hichens and K P Vyas
      Drug Metabolism and Disposition May 1993, 21 (3) 467-473;
  3. Higuchi, S

    1. You have access
      Metabolic N-demethylation of 1,3-bis[[1-cycloheptyl-3-(p- dimethylaminophenyl)ureido]methyl]benzene dihydrochloride, a novel acyl-coenzyme A:cholesterol acyltransferase inhibitor.
      T Uchida, T Usui, T Teramura, T Watanabe and S Higuchi
      Drug Metabolism and Disposition May 1993, 21 (3) 524-529;
  4. Hoffmann, K J

    1. You have access
      Presystemic elimination of the beta-blocker pafenolol in the rat after oral and intraperitoneal administration and identification of a main metabolite in both rats and humans.
      H Lennernäs, L Renberg, K J Hoffmann and C G Regårdh
      Drug Metabolism and Disposition May 1993, 21 (3) 435-440;
  5. Hoke, J F

    1. You have access
      Pharmacokinetics and metabolism of vigabatrin following a single oral dose of [14C]vigabatrin in healthy male volunteers.
      S L Durham, J F Hoke and T M Chen
      Drug Metabolism and Disposition May 1993, 21 (3) 480-484;
  6. Homnick, C F

    1. You have access
      In vivo and in vitro metabolism studies on a class III antiarrhythmic agent.
      S Vickers, C A Duncan, P H Kari, C F Homnick, J M Elliott, S M Pitzenberger, M Hichens and K P Vyas
      Drug Metabolism and Disposition May 1993, 21 (3) 467-473;

J

  1. James, R C

    1. You have access
      Inhibition by ethanol of the metabolism of cocaine to benzoylecgonine and ecgonine methyl ester in mouse and human liver.
      S M Roberts, R D Harbison and R C James
      Drug Metabolism and Disposition May 1993, 21 (3) 537-541;
  2. Johnston, M R

    1. You have access
      Influence of temperature and plasma protein on doxorubicin uptake by isolated lungs.
      R D Bongard, D L Roerig, M R Johnston, J H Linehan and C A Dawson
      Drug Metabolism and Disposition May 1993, 21 (3) 428-434;

K

  1. Kari, P H

    1. You have access
      In vivo and in vitro metabolism studies on a class III antiarrhythmic agent.
      S Vickers, C A Duncan, P H Kari, C F Homnick, J M Elliott, S M Pitzenberger, M Hichens and K P Vyas
      Drug Metabolism and Disposition May 1993, 21 (3) 467-473;
  2. Kaul, S

    1. You have access
      Absorption, disposition, and metabolism of [14C]didanosine in the beagle dog.
      S Kaul, W C Shyu, U A Shukla, K A Dandekar and R H Barbhaiya
      Drug Metabolism and Disposition May 1993, 21 (3) 447-453;
  3. Kukan, M

    1. You have access
      Characterization of nonlinear elimination of the xanthine-related drug ethimizol in 3-methylcholanthrene-induced rat liver by the "parallel-tube" model.
      M Kukan, T F Woolf, M Melus and S Bezek
      Drug Metabolism and Disposition May 1993, 21 (3) 547-550;

L

  1. Larrauri, A

    1. You have access
      The biotransformation of the ergot derivative CQA 206-291 in human, dog, and rat liver slice cultures and prediction of in vivo plasma clearance.
      A E Vickers, S Connors, M Zollinger, W A Biggi, A Larrauri, J P Vogelaar and K Brendel
      Drug Metabolism and Disposition May 1993, 21 (3) 454-459;
  2. Lennernäs, H

    1. You have access
      Presystemic elimination of the beta-blocker pafenolol in the rat after oral and intraperitoneal administration and identification of a main metabolite in both rats and humans.
      H Lennernäs, L Renberg, K J Hoffmann and C G Regårdh
      Drug Metabolism and Disposition May 1993, 21 (3) 435-440;
  3. Linehan, J H

    1. You have access
      Influence of temperature and plasma protein on doxorubicin uptake by isolated lungs.
      R D Bongard, D L Roerig, M R Johnston, J H Linehan and C A Dawson
      Drug Metabolism and Disposition May 1993, 21 (3) 428-434;

M

  1. Marathe, P H

    1. You have access
      Pharmacokinetics, absolute bioavailability, and disposition of [14C]nefazodone in the dog.
      U A Shukla, P H Marathe, K A Pittman and R H Barbhaiya
      Drug Metabolism and Disposition May 1993, 21 (3) 502-507;
  2. Matsubara, T

    1. You have access
      Enantiomer-enantiomer interaction on N-monodemethylation of diuretic in rat liver microsomes.
      M Nakano, T Chikai and T Matsubara
      Drug Metabolism and Disposition May 1993, 21 (3) 542-543;
  3. Melus, M

    1. You have access
      Characterization of nonlinear elimination of the xanthine-related drug ethimizol in 3-methylcholanthrene-induced rat liver by the "parallel-tube" model.
      M Kukan, T F Woolf, M Melus and S Bezek
      Drug Metabolism and Disposition May 1993, 21 (3) 547-550;
  4. Muindi, J F

    1. You have access
      In vitro differential metabolism of merbarone by xanthine oxidase and microsomal flavoenzymes. The role of reactive oxygen species.
      J F Muindi, Y W Stevens, R P Warrell and C W Young
      Drug Metabolism and Disposition May 1993, 21 (3) 410-414;

N

  1. Nakano, M

    1. You have access
      Enantiomer-enantiomer interaction on N-monodemethylation of diuretic in rat liver microsomes.
      M Nakano, T Chikai and T Matsubara
      Drug Metabolism and Disposition May 1993, 21 (3) 542-543;
  2. Nijmeijer, S M

    1. You have access
      Sulfamethazine as a model compound to assess sex hormone-dependent cytochrome P-450 activity in rats.
      R F Witkamp, S M Nijmeijer, H Yun, J Noordhoek and A S van Miert
      Drug Metabolism and Disposition May 1993, 21 (3) 441-446;
  3. Noordhoek, J

    1. You have access
      Sulfamethazine as a model compound to assess sex hormone-dependent cytochrome P-450 activity in rats.
      R F Witkamp, S M Nijmeijer, H Yun, J Noordhoek and A S van Miert
      Drug Metabolism and Disposition May 1993, 21 (3) 441-446;

O

  1. Okerholm, R A

    1. You have access
      Oxidation of the antihistaminic drug terfenadine in human liver microsomes. Role of cytochrome P-450 3A(4) in N-dealkylation and C-hydroxylation.
      C H Yun, R A Okerholm and F P Guengerich
      Drug Metabolism and Disposition May 1993, 21 (3) 403-409;
  2. Ong, H

    1. You have access
      Hepatic and extrahepatic metabolism of salbutamol in anesthetized rabbits.
      S Perreault, L Dumont, V Villiere, H Ong, A Adam and P du Souich
      Drug Metabolism and Disposition May 1993, 21 (3) 485-491;

P

  1. Palmer, B D

    1. You have access
      Metabolism of the experimental antitumor agent acridine carboxamide in the mouse.
      I G Robertson, B D Palmer, J W Paxton and T J Bland
      Drug Metabolism and Disposition May 1993, 21 (3) 530-536;
  2. Paxton, J W

    1. You have access
      Metabolism of the experimental antitumor agent acridine carboxamide in the mouse.
      I G Robertson, B D Palmer, J W Paxton and T J Bland
      Drug Metabolism and Disposition May 1993, 21 (3) 530-536;
  3. Perreault, S

    1. You have access
      Hepatic and extrahepatic metabolism of salbutamol in anesthetized rabbits.
      S Perreault, L Dumont, V Villiere, H Ong, A Adam and P du Souich
      Drug Metabolism and Disposition May 1993, 21 (3) 485-491;
  4. Piatkowski, T S

    1. You have access
      Increased renal drug metabolism in treadmill-exercised Fischer-344 male rats.
      T S Piatkowski, W W Day and M Weiner
      Drug Metabolism and Disposition May 1993, 21 (3) 474-479;
  5. Piper, J

    1. You have access
      Toxicokinetics of allynitrile in rats.
      M Y Farooqui, B Ybarra and J Piper
      Drug Metabolism and Disposition May 1993, 21 (3) 460-466;
  6. Pittman, K A

    1. You have access
      Pharmacokinetics, absolute bioavailability, and disposition of [14C]nefazodone in the dog.
      U A Shukla, P H Marathe, K A Pittman and R H Barbhaiya
      Drug Metabolism and Disposition May 1993, 21 (3) 502-507;
  7. Pitzenberger, S M

    1. You have access
      In vivo and in vitro metabolism studies on a class III antiarrhythmic agent.
      S Vickers, C A Duncan, P H Kari, C F Homnick, J M Elliott, S M Pitzenberger, M Hichens and K P Vyas
      Drug Metabolism and Disposition May 1993, 21 (3) 467-473;

R

  1. Regårdh, C G

    1. You have access
      Presystemic elimination of the beta-blocker pafenolol in the rat after oral and intraperitoneal administration and identification of a main metabolite in both rats and humans.
      H Lennernäs, L Renberg, K J Hoffmann and C G Regårdh
      Drug Metabolism and Disposition May 1993, 21 (3) 435-440;
  2. Renberg, L

    1. You have access
      Presystemic elimination of the beta-blocker pafenolol in the rat after oral and intraperitoneal administration and identification of a main metabolite in both rats and humans.
      H Lennernäs, L Renberg, K J Hoffmann and C G Regårdh
      Drug Metabolism and Disposition May 1993, 21 (3) 435-440;
  3. Renton, K W

    1. You have access
      Modulation of rat hepatic CYP3A1 induction by the interferon inducer polyinosinic acid-polycytidylic acid (polyic).
      E Delaporte, A E Cribb and K W Renton
      Drug Metabolism and Disposition May 1993, 21 (3) 520-523;
  4. Rietjens, I M

    1. You have access
      Qualitative and quantitative influences of ortho chlorine substituents on the microsomal metabolism of 4-toluidines.
      B Tyrakowska, S Boeren, B Geurtsen and I M Rietjens
      Drug Metabolism and Disposition May 1993, 21 (3) 508-519;
  5. Roberts, S M

    1. You have access
      Inhibition by ethanol of the metabolism of cocaine to benzoylecgonine and ecgonine methyl ester in mouse and human liver.
      S M Roberts, R D Harbison and R C James
      Drug Metabolism and Disposition May 1993, 21 (3) 537-541;
  6. Robertson, I G

    1. You have access
      Metabolism of the experimental antitumor agent acridine carboxamide in the mouse.
      I G Robertson, B D Palmer, J W Paxton and T J Bland
      Drug Metabolism and Disposition May 1993, 21 (3) 530-536;
  7. Roerig, D L

    1. You have access
      Influence of temperature and plasma protein on doxorubicin uptake by isolated lungs.
      R D Bongard, D L Roerig, M R Johnston, J H Linehan and C A Dawson
      Drug Metabolism and Disposition May 1993, 21 (3) 428-434;

S

  1. Shukla, U A

    1. You have access
      Absorption, disposition, and metabolism of [14C]didanosine in the beagle dog.
      S Kaul, W C Shyu, U A Shukla, K A Dandekar and R H Barbhaiya
      Drug Metabolism and Disposition May 1993, 21 (3) 447-453;
    2. You have access
      Pharmacokinetics, absolute bioavailability, and disposition of [14C]nefazodone in the dog.
      U A Shukla, P H Marathe, K A Pittman and R H Barbhaiya
      Drug Metabolism and Disposition May 1993, 21 (3) 502-507;
  2. Shyu, W C

    1. You have access
      Absorption, disposition, and metabolism of [14C]didanosine in the beagle dog.
      S Kaul, W C Shyu, U A Shukla, K A Dandekar and R H Barbhaiya
      Drug Metabolism and Disposition May 1993, 21 (3) 447-453;
  3. Stevens, Y W

    1. You have access
      In vitro differential metabolism of merbarone by xanthine oxidase and microsomal flavoenzymes. The role of reactive oxygen species.
      J F Muindi, Y W Stevens, R P Warrell and C W Young
      Drug Metabolism and Disposition May 1993, 21 (3) 410-414;

T

  1. Teramura, T

    1. You have access
      Metabolic N-demethylation of 1,3-bis[[1-cycloheptyl-3-(p- dimethylaminophenyl)ureido]methyl]benzene dihydrochloride, a novel acyl-coenzyme A:cholesterol acyltransferase inhibitor.
      T Uchida, T Usui, T Teramura, T Watanabe and S Higuchi
      Drug Metabolism and Disposition May 1993, 21 (3) 524-529;
  2. Tyrakowska, B

    1. You have access
      Qualitative and quantitative influences of ortho chlorine substituents on the microsomal metabolism of 4-toluidines.
      B Tyrakowska, S Boeren, B Geurtsen and I M Rietjens
      Drug Metabolism and Disposition May 1993, 21 (3) 508-519;

U

  1. Uchida, T

    1. You have access
      Metabolic N-demethylation of 1,3-bis[[1-cycloheptyl-3-(p- dimethylaminophenyl)ureido]methyl]benzene dihydrochloride, a novel acyl-coenzyme A:cholesterol acyltransferase inhibitor.
      T Uchida, T Usui, T Teramura, T Watanabe and S Higuchi
      Drug Metabolism and Disposition May 1993, 21 (3) 524-529;
  2. Usui, T

    1. You have access
      Metabolic N-demethylation of 1,3-bis[[1-cycloheptyl-3-(p- dimethylaminophenyl)ureido]methyl]benzene dihydrochloride, a novel acyl-coenzyme A:cholesterol acyltransferase inhibitor.
      T Uchida, T Usui, T Teramura, T Watanabe and S Higuchi
      Drug Metabolism and Disposition May 1993, 21 (3) 524-529;

V

  1. van Miert, A S

    1. You have access
      Sulfamethazine as a model compound to assess sex hormone-dependent cytochrome P-450 activity in rats.
      R F Witkamp, S M Nijmeijer, H Yun, J Noordhoek and A S van Miert
      Drug Metabolism and Disposition May 1993, 21 (3) 441-446;
  2. Vickers, A E

    1. You have access
      The biotransformation of the ergot derivative CQA 206-291 in human, dog, and rat liver slice cultures and prediction of in vivo plasma clearance.
      A E Vickers, S Connors, M Zollinger, W A Biggi, A Larrauri, J P Vogelaar and K Brendel
      Drug Metabolism and Disposition May 1993, 21 (3) 454-459;
  3. Vickers, S

    1. You have access
      In vivo and in vitro metabolism studies on a class III antiarrhythmic agent.
      S Vickers, C A Duncan, P H Kari, C F Homnick, J M Elliott, S M Pitzenberger, M Hichens and K P Vyas
      Drug Metabolism and Disposition May 1993, 21 (3) 467-473;
  4. Villiere, V

    1. You have access
      Hepatic and extrahepatic metabolism of salbutamol in anesthetized rabbits.
      S Perreault, L Dumont, V Villiere, H Ong, A Adam and P du Souich
      Drug Metabolism and Disposition May 1993, 21 (3) 485-491;
  5. Vinegar, A

    1. You have access
      Conditions influencing the rat liver microsomal metabolism of 2,2,-dichloro-1,1,1-trifluoroethane (HCFC-123).
      C S Godin, J M Drerup and A Vinegar
      Drug Metabolism and Disposition May 1993, 21 (3) 551-553;
  6. Vogelaar, J P

    1. You have access
      The biotransformation of the ergot derivative CQA 206-291 in human, dog, and rat liver slice cultures and prediction of in vivo plasma clearance.
      A E Vickers, S Connors, M Zollinger, W A Biggi, A Larrauri, J P Vogelaar and K Brendel
      Drug Metabolism and Disposition May 1993, 21 (3) 454-459;
  7. Vyas, K P

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      In vivo and in vitro metabolism studies on a class III antiarrhythmic agent.
      S Vickers, C A Duncan, P H Kari, C F Homnick, J M Elliott, S M Pitzenberger, M Hichens and K P Vyas
      Drug Metabolism and Disposition May 1993, 21 (3) 467-473;

W

  1. Warrell, R P

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      In vitro differential metabolism of merbarone by xanthine oxidase and microsomal flavoenzymes. The role of reactive oxygen species.
      J F Muindi, Y W Stevens, R P Warrell and C W Young
      Drug Metabolism and Disposition May 1993, 21 (3) 410-414;
  2. Watanabe, T

    1. You have access
      Metabolic N-demethylation of 1,3-bis[[1-cycloheptyl-3-(p- dimethylaminophenyl)ureido]methyl]benzene dihydrochloride, a novel acyl-coenzyme A:cholesterol acyltransferase inhibitor.
      T Uchida, T Usui, T Teramura, T Watanabe and S Higuchi
      Drug Metabolism and Disposition May 1993, 21 (3) 524-529;
  3. Weiner, M

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      Increased renal drug metabolism in treadmill-exercised Fischer-344 male rats.
      T S Piatkowski, W W Day and M Weiner
      Drug Metabolism and Disposition May 1993, 21 (3) 474-479;
  4. Witkamp, R F

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      Sulfamethazine as a model compound to assess sex hormone-dependent cytochrome P-450 activity in rats.
      R F Witkamp, S M Nijmeijer, H Yun, J Noordhoek and A S van Miert
      Drug Metabolism and Disposition May 1993, 21 (3) 441-446;
  5. Woolf, T F

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      Characterization of nonlinear elimination of the xanthine-related drug ethimizol in 3-methylcholanthrene-induced rat liver by the "parallel-tube" model.
      M Kukan, T F Woolf, M Melus and S Bezek
      Drug Metabolism and Disposition May 1993, 21 (3) 547-550;
  6. Wrighton, S A

    1. You have access
      Stereo- and regioselective N- and S-oxidation of tertiary amines and sulfides in the presence of adult human liver microsomes.
      J R Cashman, Z Yang, L Yang and S A Wrighton
      Drug Metabolism and Disposition May 1993, 21 (3) 492-501;

Y

  1. Yang, L

    1. You have access
      Stereo- and regioselective N- and S-oxidation of tertiary amines and sulfides in the presence of adult human liver microsomes.
      J R Cashman, Z Yang, L Yang and S A Wrighton
      Drug Metabolism and Disposition May 1993, 21 (3) 492-501;
  2. Yang, Z

    1. You have access
      Stereo- and regioselective N- and S-oxidation of tertiary amines and sulfides in the presence of adult human liver microsomes.
      J R Cashman, Z Yang, L Yang and S A Wrighton
      Drug Metabolism and Disposition May 1993, 21 (3) 492-501;
  3. Ybarra, B

    1. You have access
      Toxicokinetics of allynitrile in rats.
      M Y Farooqui, B Ybarra and J Piper
      Drug Metabolism and Disposition May 1993, 21 (3) 460-466;
  4. Young, C W

    1. You have access
      In vitro differential metabolism of merbarone by xanthine oxidase and microsomal flavoenzymes. The role of reactive oxygen species.
      J F Muindi, Y W Stevens, R P Warrell and C W Young
      Drug Metabolism and Disposition May 1993, 21 (3) 410-414;
  5. Yun, C H

    1. You have access
      Oxidation of the antihistaminic drug terfenadine in human liver microsomes. Role of cytochrome P-450 3A(4) in N-dealkylation and C-hydroxylation.
      C H Yun, R A Okerholm and F P Guengerich
      Drug Metabolism and Disposition May 1993, 21 (3) 403-409;
  6. Yun, H

    1. You have access
      Sulfamethazine as a model compound to assess sex hormone-dependent cytochrome P-450 activity in rats.
      R F Witkamp, S M Nijmeijer, H Yun, J Noordhoek and A S van Miert
      Drug Metabolism and Disposition May 1993, 21 (3) 441-446;

Z

  1. Zollinger, M

    1. You have access
      The biotransformation of the ergot derivative CQA 206-291 in human, dog, and rat liver slice cultures and prediction of in vivo plasma clearance.
      A E Vickers, S Connors, M Zollinger, W A Biggi, A Larrauri, J P Vogelaar and K Brendel
      Drug Metabolism and Disposition May 1993, 21 (3) 454-459;
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In this issue

Drug Metabolism and Disposition
Vol. 21, Issue 3
1 May 1993
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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