Drug Metabolism and Disposition: 21 (6)

November 01, 1993; Volume 21,Issue 6

You have access
Isolation, identification, and biological activities of oxidative metabolites of FK506, a potent immunosuppressive macrolide lactone.
K Iwasaki, T Shiraga, K Nagase, Z Tozuka, K Noda, S Sakuma, T Fujitsu, K Shimatani, A Sato and M Fujioka

Drug Metabolism and Disposition November 1993, 21 (6) 971-977;
You have access
Evidence for CYP3A-mediated N-deethylation of amiodarone in human liver microsomal fractions.
G Fabre, B Julian, B Saint-Aubert, H Joyeux and Y Berger

Drug Metabolism and Disposition November 1993, 21 (6) 978-985;
You have access
Kinetic analysis of the reaction of melphalan with water, phosphate, and glutathione.
M G Bolton, J Hilton, K D Robertson, R T Streeper, O M Colvin and D A Noe

Drug Metabolism and Disposition November 1993, 21 (6) 986-996;
You have access
Effect of colchicine-specific Fab fragments on the hepatic clearance of colchicine.
A Sabouraud, M Redureau, P Gires, M Martinet and J M Scherrmann

Drug Metabolism and Disposition November 1993, 21 (6) 997-1002;
You have access
Biotransformation of lovastatin. V. Species differences in in vivo metabolite profiles of mouse, rat, dog, and human.
R A Halpin, E H Ulm, A E Till, P H Kari, K P Vyas, D B Hunninghake and D E Duggan

Drug Metabolism and Disposition November 1993, 21 (6) 1003-1011;
You have access
Regioselective contribution of the cytochrome P-450 2D subfamily to propranolol metabolism in rat liver microsomes.
Y Masubuchi, N Kagimoto, S Narimatsu, S Fujita and T Suzuki

Drug Metabolism and Disposition November 1993, 21 (6) 1012-1016;
You have access
Disposition of a new antiinfective agent 1,3-di(4-imidazolino-2-methoxyphenoxy)propane in male rats.
I Bekersky, R J Puhl, G Hanson and S Mong

Drug Metabolism and Disposition November 1993, 21 (6) 1017-1021;
You have access
Disposition of salmeterol xinafoate in laboratory animals and humans.
G R Manchee, A Barrow, S Kulkarni, E Palmer, J Oxford, P V Colthup, J G Maconochie and M H Tarbit

Drug Metabolism and Disposition November 1993, 21 (6) 1022-1028;
You have access
CYP1A1 specificity of Verlukast epoxidation in mice, rats, rhesus monkeys, and humans.
S J Grossman, E G Herold, J M Drey, D W Alberts, D R Umbenhauer, D H Patrick, D Nicoll-Griffith, N Chauret and J A Yergey

Drug Metabolism and Disposition November 1993, 21 (6) 1029-1036;
You have access
Disposition of [14C]velnacrine maleate in rats, dogs, and humans.
R G Turcan, D Hillbeck, T E Hartley, P J Gilbert, R A Coe, J A Troke and C W Vose

Drug Metabolism and Disposition November 1993, 21 (6) 1037-1047;
You have access
Characterization of cytochrome P-450 2B6 in human liver microsomes.
M Mimura, T Baba, H Yamazaki, S Ohmori, Y Inui, F J Gonzalez, F P Guengerich and T Shimada

Drug Metabolism and Disposition November 1993, 21 (6) 1048-1056;
You have access
Distribution of 2-aminofluorene and p-aminobenzoic acid N-acetyltransferase activity in tissues of C57BL/6J rapid and B6.A-NatS slow acetylator congenic mice.
J G Chung, G N Levy and W W Weber

Drug Metabolism and Disposition November 1993, 21 (6) 1057-1063;
You have access
Head injury and cytochrome P-450 enzymes. Differential effect on mRNA and protein expression in the Fischer-344 rat.
S M Toler, A B Young, C J McClain, S I Shedlofsky, A M Bandyopadhyay and R A Blouin

Drug Metabolism and Disposition November 1993, 21 (6) 1064-1069;
You have access
Localization of glutathione conjugation activities toward bromosulfophthalein in perfused rat liver. Studies with the multiple indicator dilution technique.
Y Zhao, C A Snel, G J Mulder and K S Pang

Drug Metabolism and Disposition November 1993, 21 (6) 1070-1078;
You have access
Distribution of the anticonvulsant felbamate to cerebrospinal fluid and brain tissue of adult and neonatal rats.
V E Adusumalli, J K Wichmann, N Kucharczyk and R D Sofia

Drug Metabolism and Disposition November 1993, 21 (6) 1079-1085;
You have access
Identification of spironolactone metabolites in plasma and target organs of guinea pigs.
L E Los, A B Coddington, H G Ramjit and H D Colby

Drug Metabolism and Disposition November 1993, 21 (6) 1086-1090;
You have access
Toxicokinetics of sulfasalazine (salicylazosulfapyridine) and its metabolites in B6C3F1 mice.
W Zheng, S M Winter, M Mayersohn, J B Bishop and I G Sipes

Drug Metabolism and Disposition November 1993, 21 (6) 1091-1097;
You have access
In vivo formation of the thiol conjugates of reactive metabolites of 4-ene VPA and its analog 4-pentenoic acid.
K Kassahun and F Abbott

Drug Metabolism and Disposition November 1993, 21 (6) 1098-1106;
You have access
Kinetics of nasal carboxylesterase-mediated metabolism of vinyl acetate.
M S Bogdanffy and M L Taylor

Drug Metabolism and Disposition November 1993, 21 (6) 1107-1111;
You have access
Biodisposition studies with the acyl-coenzyme A: cholesterol acyltransferase inhibitor 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide, CI-976.
T F Woolf, A Black, Y Y Shum, W McNally, H Lee and T Chang

Drug Metabolism and Disposition November 1993, 21 (6) 1112-1118;
You have access
Analysis of phase I and phase II metabolites of tamoxifen in breast cancer patients.
G K Poon, Y C Chui, R McCague, P E Lłnning, R Feng, M G Rowlands and M Jarman

Drug Metabolism and Disposition November 1993, 21 (6) 1119-1124;
You have access
Pharmacokinetics of zopiclone and its enantiomers in Caucasian young healthy volunteers.
C Fernandez, V Maradeix, F Gimenez, A Thuillier and R Farinotti

Drug Metabolism and Disposition November 1993, 21 (6) 1125-1128;
You have access
Acute phenobarbital administration alters the disposition of acetaminophen metabolites in the rat.
K L Brouwer

Drug Metabolism and Disposition November 1993, 21 (6) 1129-1133;
You have access
Absorption, metabolism, and excretion of risperidone in humans.
G Mannens, M L Huang, W Meuldermans, J Hendrickx, R Woestenborghs and J Heykants

Drug Metabolism and Disposition November 1993, 21 (6) 1134-1141;
You have access
Pharmacokinetic study of p-chloronitrobenzene in humans suffering from acute poisoning.
T Yoshida, T Tabuchi and K Andoh

Drug Metabolism and Disposition November 1993, 21 (6) 1142-1146;
You have access
Formation of a beta-glucuronidase-resistant glucuronide conjugate of digitoxin by dog liver microsomes.
M C Castle

Drug Metabolism and Disposition November 1993, 21 (6) 1147-1150;
You have access
Disposition of morphine and its 3- and 6-glucuronide metabolites during morphine infusion in the sheep.
R W Milne, P A Sloan, C F McLean, L E Mather, R L Nation, W B Runciman, A J Rutten and A A Somogyi

Drug Metabolism and Disposition November 1993, 21 (6) 1151-1156;
You have access
In vivo and in vitro glucuronidation of the flavonoid diosmetin in rats.
J A Boutin, F Meunier, P H Lambert, P Hennig, D Bertin, B Serkiz and J P Volland

Drug Metabolism and Disposition November 1993, 21 (6) 1157-1166;
You have access
Novel cleavage of the 1,2,4-oxadiazole ring in rat metabolism of SM-6586, a dihydropyridine calcium antagonist.
M Yabuki, F Shono, I Nakatsuka and A Yoshitake

Drug Metabolism and Disposition November 1993, 21 (6) 1167-1169;
You have access
Inhibitory effects of deuterium substitution on the metabolism of sevoflurane by the rat.
M T Baker, W C Ronnenberg, J A Ruzicka, C K Chiang and J H Tinker

Drug Metabolism and Disposition November 1993, 21 (6) 1170-1171;
You have access
Relationship between the terminal disposition half-life and mean residence time in multicompartment models.
M Mayersohn and R Hamilton

Drug Metabolism and Disposition November 1993, 21 (6) 1172-1173;

Main menu

User menu

Search

Table of Contents

In this issue

Navigate

More Information

ASPET's Other Journals