Drug Metabolism and Disposition: 22 (1)

January 01, 1994; Volume 22,Issue 1

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Pharmacokinetic analysis of enterohepatic circulation of buprenorphine and its active metabolite, norbuprenorphine, in rats.
M Ohtani, H Kotaki, K Uchino, Y Sawada and T Iga

Drug Metabolism and Disposition January 1994, 22 (1) 2-7;
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Renal excretion of famotidine and role of adenosine in renal failure induced by bacterial lipopolysaccharide in rats.
T Hasegawa, M Nadai, L Wang, Y Takayama, K Kato, T Nabeshima and N Kato

Drug Metabolism and Disposition January 1994, 22 (1) 8-13;
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Codeine toxicokinetics in rats during a two-year dosed feed study.
J Yuan, J K Dunnick, E R Barnes and J W Findlay

Drug Metabolism and Disposition January 1994, 22 (1) 14-20;
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Tissue distribution and metabolism of amitriptyline after repeated administration in rats.
N Ohshima, H Kotaki, Y Sawada and T Iga

Drug Metabolism and Disposition January 1994, 22 (1) 21-25;
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Kinetics of tissue distribution and elimination of retinoid drugs in the rat. I. Acitretin.
E U Eisenhardt and M H Bickel

Drug Metabolism and Disposition January 1994, 22 (1) 26-30;
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Kinetics of tissue distribution and elimination of retinoid drugs in the rat. II. Etretinate.
E U Eisenhardt and M H Bickel

Drug Metabolism and Disposition January 1994, 22 (1) 31-35;
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Mechanisms of time-dependent kinetics of diltiazem in the isolated perfused rat liver.
M D Hussain, Y K Tam, M R Gray and R T Coutts

Drug Metabolism and Disposition January 1994, 22 (1) 36-42;
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Suppression of in vivo clearance of N-nitrosodimethylamine in mice by cotreatment with ethanol.
L M Anderson, R Koseniauskas, E S Burak, D L Logsdon, J P Carter, C L Driver, C T Gombar, P N Magee and G W Harrington

Drug Metabolism and Disposition January 1994, 22 (1) 43-49;
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Linear relationship between GABAA receptor occupancy of muscimol and glucose metabolic response in the conscious mouse brain. Clinical implication based on comparison with benzodiazepine receptor agonist.
K Ito, Y Sawada, Y Sugiyama, H Suzuki, M Hanano and T Iga

Drug Metabolism and Disposition January 1994, 22 (1) 50-54;
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Metabolic fate and pharmacokinetics of the acyclovir prodrug valaciclovir in cynomolgus monkeys.
P de Miranda and T C Burnette

Drug Metabolism and Disposition January 1994, 22 (1) 55-59;
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Metabolic disposition of the acyclovir prodrug valaciclovir in the rat.
T C Burnette and P de Miranda

Drug Metabolism and Disposition January 1994, 22 (1) 60-64;
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Induction of cytochromes P-450 2B and 3A in mice following the dietary administration of the novel cognitive enhancer linopirdine.
S Diamond, D Rakestraw, J O'Neil, G N Lam and D D Christ

Drug Metabolism and Disposition January 1994, 22 (1) 65-73;
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Metabolism of cyclophosphamide by lipoxygenases.
S Kanekal and J P Kehrer

Drug Metabolism and Disposition January 1994, 22 (1) 74-78;
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In vitro biotransformation of finasteride in rat hepatic microsomes. Isolation and characterization of metabolites.
Y Ishii, H Mukoyama and M Ohtawa

Drug Metabolism and Disposition January 1994, 22 (1) 79-84;
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FK 506 metabolism in male and female rat liver microsomes.
B Y Perotti, N Okudaira, T Prueksaritanont and L Z Benet

Drug Metabolism and Disposition January 1994, 22 (1) 85-89;
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Disposition of growth hormone-releasing peptide (SK&F 110679) in rat and dog following intravenous or subcutaneous administration.
C B Davis, C S Crysler, V K Boppana, K L Fong, G L Joseph, J J Urbanski, R A Macia and G R Rhodes

Drug Metabolism and Disposition January 1994, 22 (1) 90-98;
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Pharmacokinetics and saturable blood-brain barrier transport of biotin bound to a conjugate of avidin and a monoclonal antibody to the transferrin receptor.
Y S Kang, U Bickel and W M Pardridge

Drug Metabolism and Disposition January 1994, 22 (1) 99-105;
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Pharmacokinetic assessment of the dermal absorption of N,N-diethyl-m-toluamide (DEET) in cattle.
W G Taylor, T J Danielson, R W Spooner and L R Golsteyn

Drug Metabolism and Disposition January 1994, 22 (1) 106-112;
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Disposition and protein binding of valproic acid in the developing rat.
L J Haberer and G M Pollack

Drug Metabolism and Disposition January 1994, 22 (1) 113-119;
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Site-dependent intestinal hydrolysis of valproate and morphine glucuronide in the developing rat.
G M Pollack, A P Spencer, T L Horton and K L Brouwer

Drug Metabolism and Disposition January 1994, 22 (1) 120-123;
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Use of rat and human in vitro systems to assess the effectiveness and enzymology of deoxy-guanine analogues as prodrugs of an antiviral agent.
A W Harrell, S M Wheeler, P East, S E Clarke and R J Chenery

Drug Metabolism and Disposition January 1994, 22 (1) 124-128;
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The metabolism and excretion of risperidone after oral administration in rats and dogs.
W Meuldermans, J Hendrickx, G Mannens, K Lavrijsen, C Janssen, J Bracke, L Le Jeune, W Lauwers and J Heykants

Drug Metabolism and Disposition January 1994, 22 (1) 129-138;
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Metabolic disposition of simvastatin in patients with T-tube drainage.
H Cheng, M S Schwartz, S Vickers, J D Gilbert, R D Amin, B Depuy, L Liu, J D Rogers, S M Pond and C A Duncan

Drug Metabolism and Disposition January 1994, 22 (1) 139-142;
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Glutathione-dependent biosynthesis and bioactivation of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine, the glutathione and cysteine S-conjugates of dichloroacetylene, in rat tissues and subcellular fractions.
N Patel, G Birner, W Dekant and M W Anders

Drug Metabolism and Disposition January 1994, 22 (1) 143-147;
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Renal tubular transport of cimetidine in the isolated perfused kidney of the rat.
S P Boom, M M Moons and F G Russel

Drug Metabolism and Disposition January 1994, 22 (1) 148-153;
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Pharmacokinetics of 13-cis-, all-trans-, 13-cis-4-oxo-, and all-trans-4-oxo retinoic acid after intravenous administration in the cynomolgus monkey.
J A Sandberg, C Eckhoff, H Nau and W Slikker

Drug Metabolism and Disposition January 1994, 22 (1) 154-160;
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Monoacetyldapsone inhibition of dapsone N-hydroxylation by human and rat liver microsomes.
Y Irshaid, A Adedoyin, M Lotze and R A Branch

Drug Metabolism and Disposition January 1994, 22 (1) 161-164;
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Influence of phenobarbital induction on the enantioselective N-dechloroethylation of ifosfamide enantiomers in the rat.
C P Granvil, T Wang, G Batist and I W Wainer

Drug Metabolism and Disposition January 1994, 22 (1) 165-167;
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Drug concentrations in human brain tissue samples from epileptic patients treated with felbamate.
V E Adusumalli, J K Wichmann, N Kucharczyk, M Kamin, R D Sofia, J French, M Sperling, B Bourgeois, O Devinsky and F E Dreifuss

Drug Metabolism and Disposition January 1994, 22 (1) 168-170;
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Isolation and identification of the major urinary metabolite of m-chlorophenylpiperazine in the rat.
R F Mayol, C A Cole, K E Colson and E H Kerns

Drug Metabolism and Disposition January 1994, 22 (1) 171-174;
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Distribution and excretion of 125I-ardeparin, a low molecular weight heparin, in rats and beagle dogs.
S K Kirkman, T A Hultin and J Scatina

Drug Metabolism and Disposition January 1994, 22 (1) 175-176;
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6 alpha-Hydroxytaxol: isolation and identification of the major metabolite of taxol in human liver microsomes.
G N Kumar, J E Oatis, K R Thornburg, F J Heldrich, E S Hazard and T Walle

Drug Metabolism and Disposition January 1994, 22 (1) 177-179;
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Interaction of cimetidine with oxidized and prereduced microsomal cytochrome P-450.
S P Faux and R D Combes

Drug Metabolism and Disposition January 1994, 22 (1) 180-182;

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