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Drug Metabolism & Disposition

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  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
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Index by author

January 01, 1994; Volume 22,Issue 1
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Adedoyin, A

    1. You have access
      Monoacetyldapsone inhibition of dapsone N-hydroxylation by human and rat liver microsomes.
      Y Irshaid, A Adedoyin, M Lotze and R A Branch
      Drug Metabolism and Disposition January 1994, 22 (1) 161-164;
  2. Adusumalli, V E

    1. You have access
      Drug concentrations in human brain tissue samples from epileptic patients treated with felbamate.
      V E Adusumalli, J K Wichmann, N Kucharczyk, M Kamin, R D Sofia, J French, M Sperling, B Bourgeois, O Devinsky and F E Dreifuss
      Drug Metabolism and Disposition January 1994, 22 (1) 168-170;
  3. Amin, R D

    1. You have access
      Metabolic disposition of simvastatin in patients with T-tube drainage.
      H Cheng, M S Schwartz, S Vickers, J D Gilbert, R D Amin, B Depuy, L Liu, J D Rogers, S M Pond and C A Duncan
      Drug Metabolism and Disposition January 1994, 22 (1) 139-142;
  4. Anders, M W

    1. You have access
      Glutathione-dependent biosynthesis and bioactivation of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine, the glutathione and cysteine S-conjugates of dichloroacetylene, in rat tissues and subcellular fractions.
      N Patel, G Birner, W Dekant and M W Anders
      Drug Metabolism and Disposition January 1994, 22 (1) 143-147;
  5. Anderson, L M

    1. You have access
      Suppression of in vivo clearance of N-nitrosodimethylamine in mice by cotreatment with ethanol.
      L M Anderson, R Koseniauskas, E S Burak, D L Logsdon, J P Carter, C L Driver, C T Gombar, P N Magee and G W Harrington
      Drug Metabolism and Disposition January 1994, 22 (1) 43-49;

B

  1. Barnes, E R

    1. You have access
      Codeine toxicokinetics in rats during a two-year dosed feed study.
      J Yuan, J K Dunnick, E R Barnes and J W Findlay
      Drug Metabolism and Disposition January 1994, 22 (1) 14-20;
  2. Batist, G

    1. You have access
      Influence of phenobarbital induction on the enantioselective N-dechloroethylation of ifosfamide enantiomers in the rat.
      C P Granvil, T Wang, G Batist and I W Wainer
      Drug Metabolism and Disposition January 1994, 22 (1) 165-167;
  3. Benet, L Z

    1. You have access
      FK 506 metabolism in male and female rat liver microsomes.
      B Y Perotti, N Okudaira, T Prueksaritanont and L Z Benet
      Drug Metabolism and Disposition January 1994, 22 (1) 85-89;
  4. Bickel, M H

    1. You have access
      Kinetics of tissue distribution and elimination of retinoid drugs in the rat. I. Acitretin.
      E U Eisenhardt and M H Bickel
      Drug Metabolism and Disposition January 1994, 22 (1) 26-30;
    2. You have access
      Kinetics of tissue distribution and elimination of retinoid drugs in the rat. II. Etretinate.
      E U Eisenhardt and M H Bickel
      Drug Metabolism and Disposition January 1994, 22 (1) 31-35;
  5. Bickel, U

    1. You have access
      Pharmacokinetics and saturable blood-brain barrier transport of biotin bound to a conjugate of avidin and a monoclonal antibody to the transferrin receptor.
      Y S Kang, U Bickel and W M Pardridge
      Drug Metabolism and Disposition January 1994, 22 (1) 99-105;
  6. Birner, G

    1. You have access
      Glutathione-dependent biosynthesis and bioactivation of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine, the glutathione and cysteine S-conjugates of dichloroacetylene, in rat tissues and subcellular fractions.
      N Patel, G Birner, W Dekant and M W Anders
      Drug Metabolism and Disposition January 1994, 22 (1) 143-147;
  7. Boom, S P

    1. You have access
      Renal tubular transport of cimetidine in the isolated perfused kidney of the rat.
      S P Boom, M M Moons and F G Russel
      Drug Metabolism and Disposition January 1994, 22 (1) 148-153;
  8. Boppana, V K

    1. You have access
      Disposition of growth hormone-releasing peptide (SK&F 110679) in rat and dog following intravenous or subcutaneous administration.
      C B Davis, C S Crysler, V K Boppana, K L Fong, G L Joseph, J J Urbanski, R A Macia and G R Rhodes
      Drug Metabolism and Disposition January 1994, 22 (1) 90-98;
  9. Bourgeois, B

    1. You have access
      Drug concentrations in human brain tissue samples from epileptic patients treated with felbamate.
      V E Adusumalli, J K Wichmann, N Kucharczyk, M Kamin, R D Sofia, J French, M Sperling, B Bourgeois, O Devinsky and F E Dreifuss
      Drug Metabolism and Disposition January 1994, 22 (1) 168-170;
  10. Bracke, J

    1. You have access
      The metabolism and excretion of risperidone after oral administration in rats and dogs.
      W Meuldermans, J Hendrickx, G Mannens, K Lavrijsen, C Janssen, J Bracke, L Le Jeune, W Lauwers and J Heykants
      Drug Metabolism and Disposition January 1994, 22 (1) 129-138;
  11. Branch, R A

    1. You have access
      Monoacetyldapsone inhibition of dapsone N-hydroxylation by human and rat liver microsomes.
      Y Irshaid, A Adedoyin, M Lotze and R A Branch
      Drug Metabolism and Disposition January 1994, 22 (1) 161-164;
  12. Brouwer, K L

    1. You have access
      Site-dependent intestinal hydrolysis of valproate and morphine glucuronide in the developing rat.
      G M Pollack, A P Spencer, T L Horton and K L Brouwer
      Drug Metabolism and Disposition January 1994, 22 (1) 120-123;
  13. Burak, E S

    1. You have access
      Suppression of in vivo clearance of N-nitrosodimethylamine in mice by cotreatment with ethanol.
      L M Anderson, R Koseniauskas, E S Burak, D L Logsdon, J P Carter, C L Driver, C T Gombar, P N Magee and G W Harrington
      Drug Metabolism and Disposition January 1994, 22 (1) 43-49;
  14. Burnette, T C

    1. You have access
      Metabolic fate and pharmacokinetics of the acyclovir prodrug valaciclovir in cynomolgus monkeys.
      P de Miranda and T C Burnette
      Drug Metabolism and Disposition January 1994, 22 (1) 55-59;
    2. You have access
      Metabolic disposition of the acyclovir prodrug valaciclovir in the rat.
      T C Burnette and P de Miranda
      Drug Metabolism and Disposition January 1994, 22 (1) 60-64;

C

  1. Carter, J P

    1. You have access
      Suppression of in vivo clearance of N-nitrosodimethylamine in mice by cotreatment with ethanol.
      L M Anderson, R Koseniauskas, E S Burak, D L Logsdon, J P Carter, C L Driver, C T Gombar, P N Magee and G W Harrington
      Drug Metabolism and Disposition January 1994, 22 (1) 43-49;
  2. Chenery, R J

    1. You have access
      Use of rat and human in vitro systems to assess the effectiveness and enzymology of deoxy-guanine analogues as prodrugs of an antiviral agent.
      A W Harrell, S M Wheeler, P East, S E Clarke and R J Chenery
      Drug Metabolism and Disposition January 1994, 22 (1) 124-128;
  3. Cheng, H

    1. You have access
      Metabolic disposition of simvastatin in patients with T-tube drainage.
      H Cheng, M S Schwartz, S Vickers, J D Gilbert, R D Amin, B Depuy, L Liu, J D Rogers, S M Pond and C A Duncan
      Drug Metabolism and Disposition January 1994, 22 (1) 139-142;
  4. Christ, D D

    1. You have access
      Induction of cytochromes P-450 2B and 3A in mice following the dietary administration of the novel cognitive enhancer linopirdine.
      S Diamond, D Rakestraw, J O'Neil, G N Lam and D D Christ
      Drug Metabolism and Disposition January 1994, 22 (1) 65-73;
  5. Clarke, S E

    1. You have access
      Use of rat and human in vitro systems to assess the effectiveness and enzymology of deoxy-guanine analogues as prodrugs of an antiviral agent.
      A W Harrell, S M Wheeler, P East, S E Clarke and R J Chenery
      Drug Metabolism and Disposition January 1994, 22 (1) 124-128;
  6. Cole, C A

    1. You have access
      Isolation and identification of the major urinary metabolite of m-chlorophenylpiperazine in the rat.
      R F Mayol, C A Cole, K E Colson and E H Kerns
      Drug Metabolism and Disposition January 1994, 22 (1) 171-174;
  7. Colson, K E

    1. You have access
      Isolation and identification of the major urinary metabolite of m-chlorophenylpiperazine in the rat.
      R F Mayol, C A Cole, K E Colson and E H Kerns
      Drug Metabolism and Disposition January 1994, 22 (1) 171-174;
  8. Combes, R D

    1. You have access
      Interaction of cimetidine with oxidized and prereduced microsomal cytochrome P-450.
      S P Faux and R D Combes
      Drug Metabolism and Disposition January 1994, 22 (1) 180-182;
  9. Coutts, R T

    1. You have access
      Mechanisms of time-dependent kinetics of diltiazem in the isolated perfused rat liver.
      M D Hussain, Y K Tam, M R Gray and R T Coutts
      Drug Metabolism and Disposition January 1994, 22 (1) 36-42;
  10. Crysler, C S

    1. You have access
      Disposition of growth hormone-releasing peptide (SK&F 110679) in rat and dog following intravenous or subcutaneous administration.
      C B Davis, C S Crysler, V K Boppana, K L Fong, G L Joseph, J J Urbanski, R A Macia and G R Rhodes
      Drug Metabolism and Disposition January 1994, 22 (1) 90-98;

D

  1. Danielson, T J

    1. You have access
      Pharmacokinetic assessment of the dermal absorption of N,N-diethyl-m-toluamide (DEET) in cattle.
      W G Taylor, T J Danielson, R W Spooner and L R Golsteyn
      Drug Metabolism and Disposition January 1994, 22 (1) 106-112;
  2. Davis, C B

    1. You have access
      Disposition of growth hormone-releasing peptide (SK&F 110679) in rat and dog following intravenous or subcutaneous administration.
      C B Davis, C S Crysler, V K Boppana, K L Fong, G L Joseph, J J Urbanski, R A Macia and G R Rhodes
      Drug Metabolism and Disposition January 1994, 22 (1) 90-98;
  3. Dekant, W

    1. You have access
      Glutathione-dependent biosynthesis and bioactivation of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine, the glutathione and cysteine S-conjugates of dichloroacetylene, in rat tissues and subcellular fractions.
      N Patel, G Birner, W Dekant and M W Anders
      Drug Metabolism and Disposition January 1994, 22 (1) 143-147;
  4. de Miranda, P

    1. You have access
      Metabolic fate and pharmacokinetics of the acyclovir prodrug valaciclovir in cynomolgus monkeys.
      P de Miranda and T C Burnette
      Drug Metabolism and Disposition January 1994, 22 (1) 55-59;
    2. You have access
      Metabolic disposition of the acyclovir prodrug valaciclovir in the rat.
      T C Burnette and P de Miranda
      Drug Metabolism and Disposition January 1994, 22 (1) 60-64;
  5. Depuy, B

    1. You have access
      Metabolic disposition of simvastatin in patients with T-tube drainage.
      H Cheng, M S Schwartz, S Vickers, J D Gilbert, R D Amin, B Depuy, L Liu, J D Rogers, S M Pond and C A Duncan
      Drug Metabolism and Disposition January 1994, 22 (1) 139-142;
  6. Devinsky, O

    1. You have access
      Drug concentrations in human brain tissue samples from epileptic patients treated with felbamate.
      V E Adusumalli, J K Wichmann, N Kucharczyk, M Kamin, R D Sofia, J French, M Sperling, B Bourgeois, O Devinsky and F E Dreifuss
      Drug Metabolism and Disposition January 1994, 22 (1) 168-170;
  7. Diamond, S

    1. You have access
      Induction of cytochromes P-450 2B and 3A in mice following the dietary administration of the novel cognitive enhancer linopirdine.
      S Diamond, D Rakestraw, J O'Neil, G N Lam and D D Christ
      Drug Metabolism and Disposition January 1994, 22 (1) 65-73;
  8. Dreifuss, F E

    1. You have access
      Drug concentrations in human brain tissue samples from epileptic patients treated with felbamate.
      V E Adusumalli, J K Wichmann, N Kucharczyk, M Kamin, R D Sofia, J French, M Sperling, B Bourgeois, O Devinsky and F E Dreifuss
      Drug Metabolism and Disposition January 1994, 22 (1) 168-170;
  9. Driver, C L

    1. You have access
      Suppression of in vivo clearance of N-nitrosodimethylamine in mice by cotreatment with ethanol.
      L M Anderson, R Koseniauskas, E S Burak, D L Logsdon, J P Carter, C L Driver, C T Gombar, P N Magee and G W Harrington
      Drug Metabolism and Disposition January 1994, 22 (1) 43-49;
  10. Duncan, C A

    1. You have access
      Metabolic disposition of simvastatin in patients with T-tube drainage.
      H Cheng, M S Schwartz, S Vickers, J D Gilbert, R D Amin, B Depuy, L Liu, J D Rogers, S M Pond and C A Duncan
      Drug Metabolism and Disposition January 1994, 22 (1) 139-142;
  11. Dunnick, J K

    1. You have access
      Codeine toxicokinetics in rats during a two-year dosed feed study.
      J Yuan, J K Dunnick, E R Barnes and J W Findlay
      Drug Metabolism and Disposition January 1994, 22 (1) 14-20;

E

  1. East, P

    1. You have access
      Use of rat and human in vitro systems to assess the effectiveness and enzymology of deoxy-guanine analogues as prodrugs of an antiviral agent.
      A W Harrell, S M Wheeler, P East, S E Clarke and R J Chenery
      Drug Metabolism and Disposition January 1994, 22 (1) 124-128;
  2. Eckhoff, C

    1. You have access
      Pharmacokinetics of 13-cis-, all-trans-, 13-cis-4-oxo-, and all-trans-4-oxo retinoic acid after intravenous administration in the cynomolgus monkey.
      J A Sandberg, C Eckhoff, H Nau and W Slikker
      Drug Metabolism and Disposition January 1994, 22 (1) 154-160;
  3. Eisenhardt, E U

    1. You have access
      Kinetics of tissue distribution and elimination of retinoid drugs in the rat. I. Acitretin.
      E U Eisenhardt and M H Bickel
      Drug Metabolism and Disposition January 1994, 22 (1) 26-30;
    2. You have access
      Kinetics of tissue distribution and elimination of retinoid drugs in the rat. II. Etretinate.
      E U Eisenhardt and M H Bickel
      Drug Metabolism and Disposition January 1994, 22 (1) 31-35;

F

  1. Faux, S P

    1. You have access
      Interaction of cimetidine with oxidized and prereduced microsomal cytochrome P-450.
      S P Faux and R D Combes
      Drug Metabolism and Disposition January 1994, 22 (1) 180-182;
  2. Findlay, J W

    1. You have access
      Codeine toxicokinetics in rats during a two-year dosed feed study.
      J Yuan, J K Dunnick, E R Barnes and J W Findlay
      Drug Metabolism and Disposition January 1994, 22 (1) 14-20;
  3. Fong, K L

    1. You have access
      Disposition of growth hormone-releasing peptide (SK&F 110679) in rat and dog following intravenous or subcutaneous administration.
      C B Davis, C S Crysler, V K Boppana, K L Fong, G L Joseph, J J Urbanski, R A Macia and G R Rhodes
      Drug Metabolism and Disposition January 1994, 22 (1) 90-98;
  4. French, J

    1. You have access
      Drug concentrations in human brain tissue samples from epileptic patients treated with felbamate.
      V E Adusumalli, J K Wichmann, N Kucharczyk, M Kamin, R D Sofia, J French, M Sperling, B Bourgeois, O Devinsky and F E Dreifuss
      Drug Metabolism and Disposition January 1994, 22 (1) 168-170;

G

  1. Gilbert, J D

    1. You have access
      Metabolic disposition of simvastatin in patients with T-tube drainage.
      H Cheng, M S Schwartz, S Vickers, J D Gilbert, R D Amin, B Depuy, L Liu, J D Rogers, S M Pond and C A Duncan
      Drug Metabolism and Disposition January 1994, 22 (1) 139-142;
  2. Golsteyn, L R

    1. You have access
      Pharmacokinetic assessment of the dermal absorption of N,N-diethyl-m-toluamide (DEET) in cattle.
      W G Taylor, T J Danielson, R W Spooner and L R Golsteyn
      Drug Metabolism and Disposition January 1994, 22 (1) 106-112;
  3. Gombar, C T

    1. You have access
      Suppression of in vivo clearance of N-nitrosodimethylamine in mice by cotreatment with ethanol.
      L M Anderson, R Koseniauskas, E S Burak, D L Logsdon, J P Carter, C L Driver, C T Gombar, P N Magee and G W Harrington
      Drug Metabolism and Disposition January 1994, 22 (1) 43-49;
  4. Granvil, C P

    1. You have access
      Influence of phenobarbital induction on the enantioselective N-dechloroethylation of ifosfamide enantiomers in the rat.
      C P Granvil, T Wang, G Batist and I W Wainer
      Drug Metabolism and Disposition January 1994, 22 (1) 165-167;
  5. Gray, M R

    1. You have access
      Mechanisms of time-dependent kinetics of diltiazem in the isolated perfused rat liver.
      M D Hussain, Y K Tam, M R Gray and R T Coutts
      Drug Metabolism and Disposition January 1994, 22 (1) 36-42;

H

  1. Haberer, L J

    1. You have access
      Disposition and protein binding of valproic acid in the developing rat.
      L J Haberer and G M Pollack
      Drug Metabolism and Disposition January 1994, 22 (1) 113-119;
  2. Hanano, M

    1. You have access
      Linear relationship between GABAA receptor occupancy of muscimol and glucose metabolic response in the conscious mouse brain. Clinical implication based on comparison with benzodiazepine receptor agonist.
      K Ito, Y Sawada, Y Sugiyama, H Suzuki, M Hanano and T Iga
      Drug Metabolism and Disposition January 1994, 22 (1) 50-54;
  3. Harrell, A W

    1. You have access
      Use of rat and human in vitro systems to assess the effectiveness and enzymology of deoxy-guanine analogues as prodrugs of an antiviral agent.
      A W Harrell, S M Wheeler, P East, S E Clarke and R J Chenery
      Drug Metabolism and Disposition January 1994, 22 (1) 124-128;
  4. Harrington, G W

    1. You have access
      Suppression of in vivo clearance of N-nitrosodimethylamine in mice by cotreatment with ethanol.
      L M Anderson, R Koseniauskas, E S Burak, D L Logsdon, J P Carter, C L Driver, C T Gombar, P N Magee and G W Harrington
      Drug Metabolism and Disposition January 1994, 22 (1) 43-49;
  5. Hasegawa, T

    1. You have access
      Renal excretion of famotidine and role of adenosine in renal failure induced by bacterial lipopolysaccharide in rats.
      T Hasegawa, M Nadai, L Wang, Y Takayama, K Kato, T Nabeshima and N Kato
      Drug Metabolism and Disposition January 1994, 22 (1) 8-13;
  6. Hazard, E S

    1. You have access
      6 alpha-Hydroxytaxol: isolation and identification of the major metabolite of taxol in human liver microsomes.
      G N Kumar, J E Oatis, K R Thornburg, F J Heldrich, E S Hazard and T Walle
      Drug Metabolism and Disposition January 1994, 22 (1) 177-179;
  7. Heldrich, F J

    1. You have access
      6 alpha-Hydroxytaxol: isolation and identification of the major metabolite of taxol in human liver microsomes.
      G N Kumar, J E Oatis, K R Thornburg, F J Heldrich, E S Hazard and T Walle
      Drug Metabolism and Disposition January 1994, 22 (1) 177-179;
  8. Hendrickx, J

    1. You have access
      The metabolism and excretion of risperidone after oral administration in rats and dogs.
      W Meuldermans, J Hendrickx, G Mannens, K Lavrijsen, C Janssen, J Bracke, L Le Jeune, W Lauwers and J Heykants
      Drug Metabolism and Disposition January 1994, 22 (1) 129-138;
  9. Heykants, J

    1. You have access
      The metabolism and excretion of risperidone after oral administration in rats and dogs.
      W Meuldermans, J Hendrickx, G Mannens, K Lavrijsen, C Janssen, J Bracke, L Le Jeune, W Lauwers and J Heykants
      Drug Metabolism and Disposition January 1994, 22 (1) 129-138;
  10. Horton, T L

    1. You have access
      Site-dependent intestinal hydrolysis of valproate and morphine glucuronide in the developing rat.
      G M Pollack, A P Spencer, T L Horton and K L Brouwer
      Drug Metabolism and Disposition January 1994, 22 (1) 120-123;
  11. Hultin, T A

    1. You have access
      Distribution and excretion of 125I-ardeparin, a low molecular weight heparin, in rats and beagle dogs.
      S K Kirkman, T A Hultin and J Scatina
      Drug Metabolism and Disposition January 1994, 22 (1) 175-176;
  12. Hussain, M D

    1. You have access
      Mechanisms of time-dependent kinetics of diltiazem in the isolated perfused rat liver.
      M D Hussain, Y K Tam, M R Gray and R T Coutts
      Drug Metabolism and Disposition January 1994, 22 (1) 36-42;

I

  1. Iga, T

    1. You have access
      Tissue distribution and metabolism of amitriptyline after repeated administration in rats.
      N Ohshima, H Kotaki, Y Sawada and T Iga
      Drug Metabolism and Disposition January 1994, 22 (1) 21-25;
    2. You have access
      Pharmacokinetic analysis of enterohepatic circulation of buprenorphine and its active metabolite, norbuprenorphine, in rats.
      M Ohtani, H Kotaki, K Uchino, Y Sawada and T Iga
      Drug Metabolism and Disposition January 1994, 22 (1) 2-7;
    3. You have access
      Linear relationship between GABAA receptor occupancy of muscimol and glucose metabolic response in the conscious mouse brain. Clinical implication based on comparison with benzodiazepine receptor agonist.
      K Ito, Y Sawada, Y Sugiyama, H Suzuki, M Hanano and T Iga
      Drug Metabolism and Disposition January 1994, 22 (1) 50-54;
  2. Irshaid, Y

    1. You have access
      Monoacetyldapsone inhibition of dapsone N-hydroxylation by human and rat liver microsomes.
      Y Irshaid, A Adedoyin, M Lotze and R A Branch
      Drug Metabolism and Disposition January 1994, 22 (1) 161-164;
  3. Ishii, Y

    1. You have access
      In vitro biotransformation of finasteride in rat hepatic microsomes. Isolation and characterization of metabolites.
      Y Ishii, H Mukoyama and M Ohtawa
      Drug Metabolism and Disposition January 1994, 22 (1) 79-84;
  4. Ito, K

    1. You have access
      Linear relationship between GABAA receptor occupancy of muscimol and glucose metabolic response in the conscious mouse brain. Clinical implication based on comparison with benzodiazepine receptor agonist.
      K Ito, Y Sawada, Y Sugiyama, H Suzuki, M Hanano and T Iga
      Drug Metabolism and Disposition January 1994, 22 (1) 50-54;

J

  1. Janssen, C

    1. You have access
      The metabolism and excretion of risperidone after oral administration in rats and dogs.
      W Meuldermans, J Hendrickx, G Mannens, K Lavrijsen, C Janssen, J Bracke, L Le Jeune, W Lauwers and J Heykants
      Drug Metabolism and Disposition January 1994, 22 (1) 129-138;
  2. Joseph, G L

    1. You have access
      Disposition of growth hormone-releasing peptide (SK&F 110679) in rat and dog following intravenous or subcutaneous administration.
      C B Davis, C S Crysler, V K Boppana, K L Fong, G L Joseph, J J Urbanski, R A Macia and G R Rhodes
      Drug Metabolism and Disposition January 1994, 22 (1) 90-98;

K

  1. Kamin, M

    1. You have access
      Drug concentrations in human brain tissue samples from epileptic patients treated with felbamate.
      V E Adusumalli, J K Wichmann, N Kucharczyk, M Kamin, R D Sofia, J French, M Sperling, B Bourgeois, O Devinsky and F E Dreifuss
      Drug Metabolism and Disposition January 1994, 22 (1) 168-170;
  2. Kanekal, S

    1. You have access
      Metabolism of cyclophosphamide by lipoxygenases.
      S Kanekal and J P Kehrer
      Drug Metabolism and Disposition January 1994, 22 (1) 74-78;
  3. Kang, Y S

    1. You have access
      Pharmacokinetics and saturable blood-brain barrier transport of biotin bound to a conjugate of avidin and a monoclonal antibody to the transferrin receptor.
      Y S Kang, U Bickel and W M Pardridge
      Drug Metabolism and Disposition January 1994, 22 (1) 99-105;
  4. Kato, K

    1. You have access
      Renal excretion of famotidine and role of adenosine in renal failure induced by bacterial lipopolysaccharide in rats.
      T Hasegawa, M Nadai, L Wang, Y Takayama, K Kato, T Nabeshima and N Kato
      Drug Metabolism and Disposition January 1994, 22 (1) 8-13;
  5. Kato, N

    1. You have access
      Renal excretion of famotidine and role of adenosine in renal failure induced by bacterial lipopolysaccharide in rats.
      T Hasegawa, M Nadai, L Wang, Y Takayama, K Kato, T Nabeshima and N Kato
      Drug Metabolism and Disposition January 1994, 22 (1) 8-13;
  6. Kehrer, J P

    1. You have access
      Metabolism of cyclophosphamide by lipoxygenases.
      S Kanekal and J P Kehrer
      Drug Metabolism and Disposition January 1994, 22 (1) 74-78;
  7. Kerns, E H

    1. You have access
      Isolation and identification of the major urinary metabolite of m-chlorophenylpiperazine in the rat.
      R F Mayol, C A Cole, K E Colson and E H Kerns
      Drug Metabolism and Disposition January 1994, 22 (1) 171-174;
  8. Kirkman, S K

    1. You have access
      Distribution and excretion of 125I-ardeparin, a low molecular weight heparin, in rats and beagle dogs.
      S K Kirkman, T A Hultin and J Scatina
      Drug Metabolism and Disposition January 1994, 22 (1) 175-176;
  9. Koseniauskas, R

    1. You have access
      Suppression of in vivo clearance of N-nitrosodimethylamine in mice by cotreatment with ethanol.
      L M Anderson, R Koseniauskas, E S Burak, D L Logsdon, J P Carter, C L Driver, C T Gombar, P N Magee and G W Harrington
      Drug Metabolism and Disposition January 1994, 22 (1) 43-49;
  10. Kotaki, H

    1. You have access
      Tissue distribution and metabolism of amitriptyline after repeated administration in rats.
      N Ohshima, H Kotaki, Y Sawada and T Iga
      Drug Metabolism and Disposition January 1994, 22 (1) 21-25;
    2. You have access
      Pharmacokinetic analysis of enterohepatic circulation of buprenorphine and its active metabolite, norbuprenorphine, in rats.
      M Ohtani, H Kotaki, K Uchino, Y Sawada and T Iga
      Drug Metabolism and Disposition January 1994, 22 (1) 2-7;
  11. Kucharczyk, N

    1. You have access
      Drug concentrations in human brain tissue samples from epileptic patients treated with felbamate.
      V E Adusumalli, J K Wichmann, N Kucharczyk, M Kamin, R D Sofia, J French, M Sperling, B Bourgeois, O Devinsky and F E Dreifuss
      Drug Metabolism and Disposition January 1994, 22 (1) 168-170;
  12. Kumar, G N

    1. You have access
      6 alpha-Hydroxytaxol: isolation and identification of the major metabolite of taxol in human liver microsomes.
      G N Kumar, J E Oatis, K R Thornburg, F J Heldrich, E S Hazard and T Walle
      Drug Metabolism and Disposition January 1994, 22 (1) 177-179;

L

  1. Lam, G N

    1. You have access
      Induction of cytochromes P-450 2B and 3A in mice following the dietary administration of the novel cognitive enhancer linopirdine.
      S Diamond, D Rakestraw, J O'Neil, G N Lam and D D Christ
      Drug Metabolism and Disposition January 1994, 22 (1) 65-73;
  2. Lauwers, W

    1. You have access
      The metabolism and excretion of risperidone after oral administration in rats and dogs.
      W Meuldermans, J Hendrickx, G Mannens, K Lavrijsen, C Janssen, J Bracke, L Le Jeune, W Lauwers and J Heykants
      Drug Metabolism and Disposition January 1994, 22 (1) 129-138;
  3. Lavrijsen, K

    1. You have access
      The metabolism and excretion of risperidone after oral administration in rats and dogs.
      W Meuldermans, J Hendrickx, G Mannens, K Lavrijsen, C Janssen, J Bracke, L Le Jeune, W Lauwers and J Heykants
      Drug Metabolism and Disposition January 1994, 22 (1) 129-138;
  4. Le Jeune, L

    1. You have access
      The metabolism and excretion of risperidone after oral administration in rats and dogs.
      W Meuldermans, J Hendrickx, G Mannens, K Lavrijsen, C Janssen, J Bracke, L Le Jeune, W Lauwers and J Heykants
      Drug Metabolism and Disposition January 1994, 22 (1) 129-138;
  5. Liu, L

    1. You have access
      Metabolic disposition of simvastatin in patients with T-tube drainage.
      H Cheng, M S Schwartz, S Vickers, J D Gilbert, R D Amin, B Depuy, L Liu, J D Rogers, S M Pond and C A Duncan
      Drug Metabolism and Disposition January 1994, 22 (1) 139-142;
  6. Logsdon, D L

    1. You have access
      Suppression of in vivo clearance of N-nitrosodimethylamine in mice by cotreatment with ethanol.
      L M Anderson, R Koseniauskas, E S Burak, D L Logsdon, J P Carter, C L Driver, C T Gombar, P N Magee and G W Harrington
      Drug Metabolism and Disposition January 1994, 22 (1) 43-49;
  7. Lotze, M

    1. You have access
      Monoacetyldapsone inhibition of dapsone N-hydroxylation by human and rat liver microsomes.
      Y Irshaid, A Adedoyin, M Lotze and R A Branch
      Drug Metabolism and Disposition January 1994, 22 (1) 161-164;

M

  1. Macia, R A

    1. You have access
      Disposition of growth hormone-releasing peptide (SK&F 110679) in rat and dog following intravenous or subcutaneous administration.
      C B Davis, C S Crysler, V K Boppana, K L Fong, G L Joseph, J J Urbanski, R A Macia and G R Rhodes
      Drug Metabolism and Disposition January 1994, 22 (1) 90-98;
  2. Magee, P N

    1. You have access
      Suppression of in vivo clearance of N-nitrosodimethylamine in mice by cotreatment with ethanol.
      L M Anderson, R Koseniauskas, E S Burak, D L Logsdon, J P Carter, C L Driver, C T Gombar, P N Magee and G W Harrington
      Drug Metabolism and Disposition January 1994, 22 (1) 43-49;
  3. Mannens, G

    1. You have access
      The metabolism and excretion of risperidone after oral administration in rats and dogs.
      W Meuldermans, J Hendrickx, G Mannens, K Lavrijsen, C Janssen, J Bracke, L Le Jeune, W Lauwers and J Heykants
      Drug Metabolism and Disposition January 1994, 22 (1) 129-138;
  4. Mayol, R F

    1. You have access
      Isolation and identification of the major urinary metabolite of m-chlorophenylpiperazine in the rat.
      R F Mayol, C A Cole, K E Colson and E H Kerns
      Drug Metabolism and Disposition January 1994, 22 (1) 171-174;
  5. Meuldermans, W

    1. You have access
      The metabolism and excretion of risperidone after oral administration in rats and dogs.
      W Meuldermans, J Hendrickx, G Mannens, K Lavrijsen, C Janssen, J Bracke, L Le Jeune, W Lauwers and J Heykants
      Drug Metabolism and Disposition January 1994, 22 (1) 129-138;
  6. Moons, M M

    1. You have access
      Renal tubular transport of cimetidine in the isolated perfused kidney of the rat.
      S P Boom, M M Moons and F G Russel
      Drug Metabolism and Disposition January 1994, 22 (1) 148-153;
  7. Mukoyama, H

    1. You have access
      In vitro biotransformation of finasteride in rat hepatic microsomes. Isolation and characterization of metabolites.
      Y Ishii, H Mukoyama and M Ohtawa
      Drug Metabolism and Disposition January 1994, 22 (1) 79-84;

N

  1. Nabeshima, T

    1. You have access
      Renal excretion of famotidine and role of adenosine in renal failure induced by bacterial lipopolysaccharide in rats.
      T Hasegawa, M Nadai, L Wang, Y Takayama, K Kato, T Nabeshima and N Kato
      Drug Metabolism and Disposition January 1994, 22 (1) 8-13;
  2. Nadai, M

    1. You have access
      Renal excretion of famotidine and role of adenosine in renal failure induced by bacterial lipopolysaccharide in rats.
      T Hasegawa, M Nadai, L Wang, Y Takayama, K Kato, T Nabeshima and N Kato
      Drug Metabolism and Disposition January 1994, 22 (1) 8-13;
  3. Nau, H

    1. You have access
      Pharmacokinetics of 13-cis-, all-trans-, 13-cis-4-oxo-, and all-trans-4-oxo retinoic acid after intravenous administration in the cynomolgus monkey.
      J A Sandberg, C Eckhoff, H Nau and W Slikker
      Drug Metabolism and Disposition January 1994, 22 (1) 154-160;

O

  1. O'Neil, J

    1. You have access
      Induction of cytochromes P-450 2B and 3A in mice following the dietary administration of the novel cognitive enhancer linopirdine.
      S Diamond, D Rakestraw, J O'Neil, G N Lam and D D Christ
      Drug Metabolism and Disposition January 1994, 22 (1) 65-73;
  2. Oatis, J E

    1. You have access
      6 alpha-Hydroxytaxol: isolation and identification of the major metabolite of taxol in human liver microsomes.
      G N Kumar, J E Oatis, K R Thornburg, F J Heldrich, E S Hazard and T Walle
      Drug Metabolism and Disposition January 1994, 22 (1) 177-179;
  3. Ohshima, N

    1. You have access
      Tissue distribution and metabolism of amitriptyline after repeated administration in rats.
      N Ohshima, H Kotaki, Y Sawada and T Iga
      Drug Metabolism and Disposition January 1994, 22 (1) 21-25;
  4. Ohtani, M

    1. You have access
      Pharmacokinetic analysis of enterohepatic circulation of buprenorphine and its active metabolite, norbuprenorphine, in rats.
      M Ohtani, H Kotaki, K Uchino, Y Sawada and T Iga
      Drug Metabolism and Disposition January 1994, 22 (1) 2-7;
  5. Ohtawa, M

    1. You have access
      In vitro biotransformation of finasteride in rat hepatic microsomes. Isolation and characterization of metabolites.
      Y Ishii, H Mukoyama and M Ohtawa
      Drug Metabolism and Disposition January 1994, 22 (1) 79-84;
  6. Okudaira, N

    1. You have access
      FK 506 metabolism in male and female rat liver microsomes.
      B Y Perotti, N Okudaira, T Prueksaritanont and L Z Benet
      Drug Metabolism and Disposition January 1994, 22 (1) 85-89;

P

  1. Pardridge, W M

    1. You have access
      Pharmacokinetics and saturable blood-brain barrier transport of biotin bound to a conjugate of avidin and a monoclonal antibody to the transferrin receptor.
      Y S Kang, U Bickel and W M Pardridge
      Drug Metabolism and Disposition January 1994, 22 (1) 99-105;
  2. Patel, N

    1. You have access
      Glutathione-dependent biosynthesis and bioactivation of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine, the glutathione and cysteine S-conjugates of dichloroacetylene, in rat tissues and subcellular fractions.
      N Patel, G Birner, W Dekant and M W Anders
      Drug Metabolism and Disposition January 1994, 22 (1) 143-147;
  3. Perotti, B Y

    1. You have access
      FK 506 metabolism in male and female rat liver microsomes.
      B Y Perotti, N Okudaira, T Prueksaritanont and L Z Benet
      Drug Metabolism and Disposition January 1994, 22 (1) 85-89;
  4. Pollack, G M

    1. You have access
      Disposition and protein binding of valproic acid in the developing rat.
      L J Haberer and G M Pollack
      Drug Metabolism and Disposition January 1994, 22 (1) 113-119;
    2. You have access
      Site-dependent intestinal hydrolysis of valproate and morphine glucuronide in the developing rat.
      G M Pollack, A P Spencer, T L Horton and K L Brouwer
      Drug Metabolism and Disposition January 1994, 22 (1) 120-123;
  5. Pond, S M

    1. You have access
      Metabolic disposition of simvastatin in patients with T-tube drainage.
      H Cheng, M S Schwartz, S Vickers, J D Gilbert, R D Amin, B Depuy, L Liu, J D Rogers, S M Pond and C A Duncan
      Drug Metabolism and Disposition January 1994, 22 (1) 139-142;
  6. Prueksaritanont, T

    1. You have access
      FK 506 metabolism in male and female rat liver microsomes.
      B Y Perotti, N Okudaira, T Prueksaritanont and L Z Benet
      Drug Metabolism and Disposition January 1994, 22 (1) 85-89;

R

  1. Rakestraw, D

    1. You have access
      Induction of cytochromes P-450 2B and 3A in mice following the dietary administration of the novel cognitive enhancer linopirdine.
      S Diamond, D Rakestraw, J O'Neil, G N Lam and D D Christ
      Drug Metabolism and Disposition January 1994, 22 (1) 65-73;
  2. Rhodes, G R

    1. You have access
      Disposition of growth hormone-releasing peptide (SK&F 110679) in rat and dog following intravenous or subcutaneous administration.
      C B Davis, C S Crysler, V K Boppana, K L Fong, G L Joseph, J J Urbanski, R A Macia and G R Rhodes
      Drug Metabolism and Disposition January 1994, 22 (1) 90-98;
  3. Rogers, J D

    1. You have access
      Metabolic disposition of simvastatin in patients with T-tube drainage.
      H Cheng, M S Schwartz, S Vickers, J D Gilbert, R D Amin, B Depuy, L Liu, J D Rogers, S M Pond and C A Duncan
      Drug Metabolism and Disposition January 1994, 22 (1) 139-142;
  4. Russel, F G

    1. You have access
      Renal tubular transport of cimetidine in the isolated perfused kidney of the rat.
      S P Boom, M M Moons and F G Russel
      Drug Metabolism and Disposition January 1994, 22 (1) 148-153;

S

  1. Sandberg, J A

    1. You have access
      Pharmacokinetics of 13-cis-, all-trans-, 13-cis-4-oxo-, and all-trans-4-oxo retinoic acid after intravenous administration in the cynomolgus monkey.
      J A Sandberg, C Eckhoff, H Nau and W Slikker
      Drug Metabolism and Disposition January 1994, 22 (1) 154-160;
  2. Sawada, Y

    1. You have access
      Tissue distribution and metabolism of amitriptyline after repeated administration in rats.
      N Ohshima, H Kotaki, Y Sawada and T Iga
      Drug Metabolism and Disposition January 1994, 22 (1) 21-25;
    2. You have access
      Pharmacokinetic analysis of enterohepatic circulation of buprenorphine and its active metabolite, norbuprenorphine, in rats.
      M Ohtani, H Kotaki, K Uchino, Y Sawada and T Iga
      Drug Metabolism and Disposition January 1994, 22 (1) 2-7;
    3. You have access
      Linear relationship between GABAA receptor occupancy of muscimol and glucose metabolic response in the conscious mouse brain. Clinical implication based on comparison with benzodiazepine receptor agonist.
      K Ito, Y Sawada, Y Sugiyama, H Suzuki, M Hanano and T Iga
      Drug Metabolism and Disposition January 1994, 22 (1) 50-54;
  3. Scatina, J

    1. You have access
      Distribution and excretion of 125I-ardeparin, a low molecular weight heparin, in rats and beagle dogs.
      S K Kirkman, T A Hultin and J Scatina
      Drug Metabolism and Disposition January 1994, 22 (1) 175-176;
  4. Schwartz, M S

    1. You have access
      Metabolic disposition of simvastatin in patients with T-tube drainage.
      H Cheng, M S Schwartz, S Vickers, J D Gilbert, R D Amin, B Depuy, L Liu, J D Rogers, S M Pond and C A Duncan
      Drug Metabolism and Disposition January 1994, 22 (1) 139-142;
  5. Slikker, W

    1. You have access
      Pharmacokinetics of 13-cis-, all-trans-, 13-cis-4-oxo-, and all-trans-4-oxo retinoic acid after intravenous administration in the cynomolgus monkey.
      J A Sandberg, C Eckhoff, H Nau and W Slikker
      Drug Metabolism and Disposition January 1994, 22 (1) 154-160;
  6. Sofia, R D

    1. You have access
      Drug concentrations in human brain tissue samples from epileptic patients treated with felbamate.
      V E Adusumalli, J K Wichmann, N Kucharczyk, M Kamin, R D Sofia, J French, M Sperling, B Bourgeois, O Devinsky and F E Dreifuss
      Drug Metabolism and Disposition January 1994, 22 (1) 168-170;
  7. Spencer, A P

    1. You have access
      Site-dependent intestinal hydrolysis of valproate and morphine glucuronide in the developing rat.
      G M Pollack, A P Spencer, T L Horton and K L Brouwer
      Drug Metabolism and Disposition January 1994, 22 (1) 120-123;
  8. Sperling, M

    1. You have access
      Drug concentrations in human brain tissue samples from epileptic patients treated with felbamate.
      V E Adusumalli, J K Wichmann, N Kucharczyk, M Kamin, R D Sofia, J French, M Sperling, B Bourgeois, O Devinsky and F E Dreifuss
      Drug Metabolism and Disposition January 1994, 22 (1) 168-170;
  9. Spooner, R W

    1. You have access
      Pharmacokinetic assessment of the dermal absorption of N,N-diethyl-m-toluamide (DEET) in cattle.
      W G Taylor, T J Danielson, R W Spooner and L R Golsteyn
      Drug Metabolism and Disposition January 1994, 22 (1) 106-112;
  10. Sugiyama, Y

    1. You have access
      Linear relationship between GABAA receptor occupancy of muscimol and glucose metabolic response in the conscious mouse brain. Clinical implication based on comparison with benzodiazepine receptor agonist.
      K Ito, Y Sawada, Y Sugiyama, H Suzuki, M Hanano and T Iga
      Drug Metabolism and Disposition January 1994, 22 (1) 50-54;
  11. Suzuki, H

    1. You have access
      Linear relationship between GABAA receptor occupancy of muscimol and glucose metabolic response in the conscious mouse brain. Clinical implication based on comparison with benzodiazepine receptor agonist.
      K Ito, Y Sawada, Y Sugiyama, H Suzuki, M Hanano and T Iga
      Drug Metabolism and Disposition January 1994, 22 (1) 50-54;

T

  1. Takayama, Y

    1. You have access
      Renal excretion of famotidine and role of adenosine in renal failure induced by bacterial lipopolysaccharide in rats.
      T Hasegawa, M Nadai, L Wang, Y Takayama, K Kato, T Nabeshima and N Kato
      Drug Metabolism and Disposition January 1994, 22 (1) 8-13;
  2. Tam, Y K

    1. You have access
      Mechanisms of time-dependent kinetics of diltiazem in the isolated perfused rat liver.
      M D Hussain, Y K Tam, M R Gray and R T Coutts
      Drug Metabolism and Disposition January 1994, 22 (1) 36-42;
  3. Taylor, W G

    1. You have access
      Pharmacokinetic assessment of the dermal absorption of N,N-diethyl-m-toluamide (DEET) in cattle.
      W G Taylor, T J Danielson, R W Spooner and L R Golsteyn
      Drug Metabolism and Disposition January 1994, 22 (1) 106-112;
  4. Thornburg, K R

    1. You have access
      6 alpha-Hydroxytaxol: isolation and identification of the major metabolite of taxol in human liver microsomes.
      G N Kumar, J E Oatis, K R Thornburg, F J Heldrich, E S Hazard and T Walle
      Drug Metabolism and Disposition January 1994, 22 (1) 177-179;

U

  1. Uchino, K

    1. You have access
      Pharmacokinetic analysis of enterohepatic circulation of buprenorphine and its active metabolite, norbuprenorphine, in rats.
      M Ohtani, H Kotaki, K Uchino, Y Sawada and T Iga
      Drug Metabolism and Disposition January 1994, 22 (1) 2-7;
  2. Urbanski, J J

    1. You have access
      Disposition of growth hormone-releasing peptide (SK&F 110679) in rat and dog following intravenous or subcutaneous administration.
      C B Davis, C S Crysler, V K Boppana, K L Fong, G L Joseph, J J Urbanski, R A Macia and G R Rhodes
      Drug Metabolism and Disposition January 1994, 22 (1) 90-98;

V

  1. Vickers, S

    1. You have access
      Metabolic disposition of simvastatin in patients with T-tube drainage.
      H Cheng, M S Schwartz, S Vickers, J D Gilbert, R D Amin, B Depuy, L Liu, J D Rogers, S M Pond and C A Duncan
      Drug Metabolism and Disposition January 1994, 22 (1) 139-142;

W

  1. Wainer, I W

    1. You have access
      Influence of phenobarbital induction on the enantioselective N-dechloroethylation of ifosfamide enantiomers in the rat.
      C P Granvil, T Wang, G Batist and I W Wainer
      Drug Metabolism and Disposition January 1994, 22 (1) 165-167;
  2. Walle, T

    1. You have access
      6 alpha-Hydroxytaxol: isolation and identification of the major metabolite of taxol in human liver microsomes.
      G N Kumar, J E Oatis, K R Thornburg, F J Heldrich, E S Hazard and T Walle
      Drug Metabolism and Disposition January 1994, 22 (1) 177-179;
  3. Wang, L

    1. You have access
      Renal excretion of famotidine and role of adenosine in renal failure induced by bacterial lipopolysaccharide in rats.
      T Hasegawa, M Nadai, L Wang, Y Takayama, K Kato, T Nabeshima and N Kato
      Drug Metabolism and Disposition January 1994, 22 (1) 8-13;
  4. Wang, T

    1. You have access
      Influence of phenobarbital induction on the enantioselective N-dechloroethylation of ifosfamide enantiomers in the rat.
      C P Granvil, T Wang, G Batist and I W Wainer
      Drug Metabolism and Disposition January 1994, 22 (1) 165-167;
  5. Wheeler, S M

    1. You have access
      Use of rat and human in vitro systems to assess the effectiveness and enzymology of deoxy-guanine analogues as prodrugs of an antiviral agent.
      A W Harrell, S M Wheeler, P East, S E Clarke and R J Chenery
      Drug Metabolism and Disposition January 1994, 22 (1) 124-128;
  6. Wichmann, J K

    1. You have access
      Drug concentrations in human brain tissue samples from epileptic patients treated with felbamate.
      V E Adusumalli, J K Wichmann, N Kucharczyk, M Kamin, R D Sofia, J French, M Sperling, B Bourgeois, O Devinsky and F E Dreifuss
      Drug Metabolism and Disposition January 1994, 22 (1) 168-170;

Y

  1. Yuan, J

    1. You have access
      Codeine toxicokinetics in rats during a two-year dosed feed study.
      J Yuan, J K Dunnick, E R Barnes and J W Findlay
      Drug Metabolism and Disposition January 1994, 22 (1) 14-20;
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In this issue

Drug Metabolism and Disposition
Vol. 22, Issue 1
1 Jan 1994
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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