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Drug Metabolism & Disposition

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  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
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Index by author

July 01, 1994; Volume 22,Issue 4
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Alary, J

    1. You have access
      Evidence for new metabolic pathways of chloramphenicol in the duck.
      J P Cravedi, M Baradat, L Debrauwer, J Alary, J Tulliez and G Bories
      Drug Metabolism and Disposition July 1994, 22 (4) 578-583;
  2. Anders, M W

    1. You have access
      Gas-uptake pharmacokinetics of 2,2-dichloro-1,1,1-trifluoroethane (HCFC-123).
      G D Loizou, G Urban, W Dekant and M W Anders
      Drug Metabolism and Disposition July 1994, 22 (4) 511-517;

B

  1. Bading, J R

    1. You have access
      Transport limits cellular entry of hepatic arterially injected 5-[18F]fluoro-2'-deoxyuridine in human intrahepatic tumors.
      J R Bading, E R Sigurdson, R D Finn, S D Yeh, J Ginos, N E Kemeny and S M Larson
      Drug Metabolism and Disposition July 1994, 22 (4) 643-650;
  2. Baillie, T A

    1. You have access
      Metabolic chiral inversion of stiripentol in the rat. I. Mechanistic studies.
      K Zhang, C Tang, M Rashed, D Cui, F Tombret, H Botte, F Lepage, R H Levy and T A Baillie
      Drug Metabolism and Disposition July 1994, 22 (4) 544-553;
    2. You have access
      Metabolic chiral inversion of stiripentol in the rat. II. Influence of route of administration.
      C Tang, K Zhang, F Lepage, R H Levy and T A Baillie
      Drug Metabolism and Disposition July 1994, 22 (4) 554-560;
  3. Baradat, M

    1. You have access
      Evidence for new metabolic pathways of chloramphenicol in the duck.
      J P Cravedi, M Baradat, L Debrauwer, J Alary, J Tulliez and G Bories
      Drug Metabolism and Disposition July 1994, 22 (4) 578-583;
  4. Baudry, J P

    1. You have access
      Disposition and metabolism of O6-alkylguanine-DNA alkyltransferase inhibitor in nude mice bearing human melanoma.
      C Cussac, E Mounetou, M Rapp, J C Madelmont, J C Maurizis, P Labarre, P Chollet, J L Chabard, D Godeneche and J P Baudry
      Drug Metabolism and Disposition July 1994, 22 (4) 637-642;
  5. Borchardt, R T

    1. You have access
      Metabolism of L-alpha-methyldopa in cultured human intestinal epithelial (Caco-2) cell monolayers. Comparison with metabolism in vivo.
      P J Chikhale and R T Borchardt
      Drug Metabolism and Disposition July 1994, 22 (4) 592-600;
  6. Bories, G

    1. You have access
      Evidence for new metabolic pathways of chloramphenicol in the duck.
      J P Cravedi, M Baradat, L Debrauwer, J Alary, J Tulliez and G Bories
      Drug Metabolism and Disposition July 1994, 22 (4) 578-583;
  7. Botte, H

    1. You have access
      Metabolic chiral inversion of stiripentol in the rat. I. Mechanistic studies.
      K Zhang, C Tang, M Rashed, D Cui, F Tombret, H Botte, F Lepage, R H Levy and T A Baillie
      Drug Metabolism and Disposition July 1994, 22 (4) 544-553;

C

  1. Caldwell, J

    1. You have access
      Metabolic fate of [3H]-l-menthol in the rat.
      T Yamaguchi, J Caldwell and P B Farmer
      Drug Metabolism and Disposition July 1994, 22 (4) 616-624;
  2. Chabard, J L

    1. You have access
      Disposition and metabolism of O6-alkylguanine-DNA alkyltransferase inhibitor in nude mice bearing human melanoma.
      C Cussac, E Mounetou, M Rapp, J C Madelmont, J C Maurizis, P Labarre, P Chollet, J L Chabard, D Godeneche and J P Baudry
      Drug Metabolism and Disposition July 1994, 22 (4) 637-642;
  3. Chen, C F

    1. You have access
      Disposition of magnolol after intravenous bolus and infusion in rabbits.
      T H Tsai, C J Chou and C F Chen
      Drug Metabolism and Disposition July 1994, 22 (4) 518-521;
  4. Chen, L

    1. You have access
      Effects of flavonoids on cytochrome P450-dependent acetaminophen metabolism in rats and human liver microsomes.
      Y Li, E Wang, C J Patten, L Chen and C S Yang
      Drug Metabolism and Disposition July 1994, 22 (4) 566-571;
  5. Chikhale, P J

    1. You have access
      Metabolism of L-alpha-methyldopa in cultured human intestinal epithelial (Caco-2) cell monolayers. Comparison with metabolism in vivo.
      P J Chikhale and R T Borchardt
      Drug Metabolism and Disposition July 1994, 22 (4) 592-600;
  6. Chiu, S H

    1. You have access
      N-glucuronidation reactions. II. Relative N-glucuronidation reactivity of methylbiphenyl tetrazole, methylbiphenyl triazole, and methylbiphenyl imidazole in rat, monkey, and human hepatic microsomes.
      S W Huskey, G A Doss, R R Miller, W R Schoen and S H Chiu
      Drug Metabolism and Disposition July 1994, 22 (4) 651-658;
    2. You have access
      N-glucuronidation reactions. III. Regioselectivity of N-glucuronidation of methylbiphenyl tetrazole, methylbiphenyl triazole, and methylbiphenyl imidazole using human and rat recombinant UDP-glucuronosyltransferases stably expressed in V79 cells.
      S E Huskey, J Magdalou, M Ouzzine, G Siest and S H Chiu
      Drug Metabolism and Disposition July 1994, 22 (4) 659-662;
  7. Chollet, P

    1. You have access
      Disposition and metabolism of O6-alkylguanine-DNA alkyltransferase inhibitor in nude mice bearing human melanoma.
      C Cussac, E Mounetou, M Rapp, J C Madelmont, J C Maurizis, P Labarre, P Chollet, J L Chabard, D Godeneche and J P Baudry
      Drug Metabolism and Disposition July 1994, 22 (4) 637-642;
  8. Chou, C J

    1. You have access
      Disposition of magnolol after intravenous bolus and infusion in rabbits.
      T H Tsai, C J Chou and C F Chen
      Drug Metabolism and Disposition July 1994, 22 (4) 518-521;
  9. Colletti, A E

    1. You have access
      Disposition and metabolism of the hypoglycemic agent pioglitazone in rats.
      P A Krieter, A E Colletti, G A Doss and R R Miller
      Drug Metabolism and Disposition July 1994, 22 (4) 625-630;
  10. Coutts, R T

    1. You have access
      Kinetic interactions of lidocaine, diphenhydramine, and verapamil with diltiazem. A study using isolated perfused rat liver.
      M D Hussain, Y K Tam, M R Gray and R T Coutts
      Drug Metabolism and Disposition July 1994, 22 (4) 530-536;
  11. Cravedi, J P

    1. You have access
      Evidence for new metabolic pathways of chloramphenicol in the duck.
      J P Cravedi, M Baradat, L Debrauwer, J Alary, J Tulliez and G Bories
      Drug Metabolism and Disposition July 1994, 22 (4) 578-583;
  12. Crawford, S T

    1. You have access
      Chronic voluntary exercise may alter hepatobiliary clearance of endogenous and exogenous chemicals in rats.
      J B Watkins, S T Crawford and R A Sanders
      Drug Metabolism and Disposition July 1994, 22 (4) 537-543;
  13. Cui, D

    1. You have access
      Metabolic chiral inversion of stiripentol in the rat. I. Mechanistic studies.
      K Zhang, C Tang, M Rashed, D Cui, F Tombret, H Botte, F Lepage, R H Levy and T A Baillie
      Drug Metabolism and Disposition July 1994, 22 (4) 544-553;
  14. Cussac, C

    1. You have access
      Disposition and metabolism of O6-alkylguanine-DNA alkyltransferase inhibitor in nude mice bearing human melanoma.
      C Cussac, E Mounetou, M Rapp, J C Madelmont, J C Maurizis, P Labarre, P Chollet, J L Chabard, D Godeneche and J P Baudry
      Drug Metabolism and Disposition July 1994, 22 (4) 637-642;

D

  1. Darbyshire, J F

    1. You have access
      Theoretical kinetics of sequential metabolism in vitro. Study of the formation of 16 alpha-hydroxyandrostenedione from testosterone by purified rat P450 2C11.
      K Sugiyama, K Nagata, J R Gillette and J F Darbyshire
      Drug Metabolism and Disposition July 1994, 22 (4) 584-591;
  2. Debrauwer, L

    1. You have access
      Evidence for new metabolic pathways of chloramphenicol in the duck.
      J P Cravedi, M Baradat, L Debrauwer, J Alary, J Tulliez and G Bories
      Drug Metabolism and Disposition July 1994, 22 (4) 578-583;
  3. Dekant, W

    1. You have access
      Gas-uptake pharmacokinetics of 2,2-dichloro-1,1,1-trifluoroethane (HCFC-123).
      G D Loizou, G Urban, W Dekant and M W Anders
      Drug Metabolism and Disposition July 1994, 22 (4) 511-517;
  4. Doss, G A

    1. You have access
      Disposition and metabolism of the hypoglycemic agent pioglitazone in rats.
      P A Krieter, A E Colletti, G A Doss and R R Miller
      Drug Metabolism and Disposition July 1994, 22 (4) 625-630;
    2. You have access
      N-glucuronidation reactions. II. Relative N-glucuronidation reactivity of methylbiphenyl tetrazole, methylbiphenyl triazole, and methylbiphenyl imidazole in rat, monkey, and human hepatic microsomes.
      S W Huskey, G A Doss, R R Miller, W R Schoen and S H Chiu
      Drug Metabolism and Disposition July 1994, 22 (4) 651-658;
  5. Duncan, C A

    1. You have access
      Disposition of MK-852, a fibrinogen receptor antagonist, in rats and dogs.
      S Vickers, C A Duncan, A S Yuan and K P Vyas
      Drug Metabolism and Disposition July 1994, 22 (4) 631-636;

F

  1. Farmer, P B

    1. You have access
      Metabolic fate of [3H]-l-menthol in the rat.
      T Yamaguchi, J Caldwell and P B Farmer
      Drug Metabolism and Disposition July 1994, 22 (4) 616-624;
  2. Finley, B L

    1. You have access
      Urinary excretion of chromium by humans following ingestion of chromium picolinate. Implications for biomonitoring.
      M L Gargas, R L Norton, D J Paustenbach and B L Finley
      Drug Metabolism and Disposition July 1994, 22 (4) 522-529;
  3. Finn, R D

    1. You have access
      Transport limits cellular entry of hepatic arterially injected 5-[18F]fluoro-2'-deoxyuridine in human intrahepatic tumors.
      J R Bading, E R Sigurdson, R D Finn, S D Yeh, J Ginos, N E Kemeny and S M Larson
      Drug Metabolism and Disposition July 1994, 22 (4) 643-650;

G

  1. Gargas, M L

    1. You have access
      Urinary excretion of chromium by humans following ingestion of chromium picolinate. Implications for biomonitoring.
      M L Gargas, R L Norton, D J Paustenbach and B L Finley
      Drug Metabolism and Disposition July 1994, 22 (4) 522-529;
  2. Gillette, J R

    1. You have access
      Theoretical kinetics of sequential metabolism in vitro. Study of the formation of 16 alpha-hydroxyandrostenedione from testosterone by purified rat P450 2C11.
      K Sugiyama, K Nagata, J R Gillette and J F Darbyshire
      Drug Metabolism and Disposition July 1994, 22 (4) 584-591;
  3. Ginos, J

    1. You have access
      Transport limits cellular entry of hepatic arterially injected 5-[18F]fluoro-2'-deoxyuridine in human intrahepatic tumors.
      J R Bading, E R Sigurdson, R D Finn, S D Yeh, J Ginos, N E Kemeny and S M Larson
      Drug Metabolism and Disposition July 1994, 22 (4) 643-650;
  4. Godeneche, D

    1. You have access
      Disposition and metabolism of O6-alkylguanine-DNA alkyltransferase inhibitor in nude mice bearing human melanoma.
      C Cussac, E Mounetou, M Rapp, J C Madelmont, J C Maurizis, P Labarre, P Chollet, J L Chabard, D Godeneche and J P Baudry
      Drug Metabolism and Disposition July 1994, 22 (4) 637-642;
  5. Gray, M R

    1. You have access
      Kinetic interactions of lidocaine, diphenhydramine, and verapamil with diltiazem. A study using isolated perfused rat liver.
      M D Hussain, Y K Tam, M R Gray and R T Coutts
      Drug Metabolism and Disposition July 1994, 22 (4) 530-536;

H

  1. Hasegawa, T

    1. You have access
      Alterations in the pharmacokinetics and protein binding of enprofylline in Eisai hyperbilirubinemic rats.
      M Nadai, T Hasegawa, L Wang, O Tagaya and T Nabeshima
      Drug Metabolism and Disposition July 1994, 22 (4) 561-565;
  2. Hasegawa, Y

    1. You have access
      Pharmacokinetics of RU44403, an active form of newly developed angiotensin-converting enzyme inhibitor (RU44570) in the rat.
      M Hirayama, A Kurihara, T Manabe and Y Hasegawa
      Drug Metabolism and Disposition July 1994, 22 (4) 601-606;
  3. Hill, B A

    1. You have access
      Metabolism and toxicity of 2-bromo-(diglutathion-S-yl)-hydroquinone and 2-bromo-3-(glutathion-S-yl)hydroquinone in the in situ perfused rat kidney.
      M I Rivera, L M Hinojosa, B A Hill, S S Lau and T J Monks
      Drug Metabolism and Disposition July 1994, 22 (4) 503-510;
  4. Hinojosa, L M

    1. You have access
      Metabolism and toxicity of 2-bromo-(diglutathion-S-yl)-hydroquinone and 2-bromo-3-(glutathion-S-yl)hydroquinone in the in situ perfused rat kidney.
      M I Rivera, L M Hinojosa, B A Hill, S S Lau and T J Monks
      Drug Metabolism and Disposition July 1994, 22 (4) 503-510;
  5. Hirayama, M

    1. You have access
      Pharmacokinetics of RU44403, an active form of newly developed angiotensin-converting enzyme inhibitor (RU44570) in the rat.
      M Hirayama, A Kurihara, T Manabe and Y Hasegawa
      Drug Metabolism and Disposition July 1994, 22 (4) 601-606;
  6. Huskey, S E

    1. You have access
      N-glucuronidation reactions. III. Regioselectivity of N-glucuronidation of methylbiphenyl tetrazole, methylbiphenyl triazole, and methylbiphenyl imidazole using human and rat recombinant UDP-glucuronosyltransferases stably expressed in V79 cells.
      S E Huskey, J Magdalou, M Ouzzine, G Siest and S H Chiu
      Drug Metabolism and Disposition July 1994, 22 (4) 659-662;
  7. Huskey, S W

    1. You have access
      N-glucuronidation reactions. II. Relative N-glucuronidation reactivity of methylbiphenyl tetrazole, methylbiphenyl triazole, and methylbiphenyl imidazole in rat, monkey, and human hepatic microsomes.
      S W Huskey, G A Doss, R R Miller, W R Schoen and S H Chiu
      Drug Metabolism and Disposition July 1994, 22 (4) 651-658;
  8. Hussain, M D

    1. You have access
      Kinetic interactions of lidocaine, diphenhydramine, and verapamil with diltiazem. A study using isolated perfused rat liver.
      M D Hussain, Y K Tam, M R Gray and R T Coutts
      Drug Metabolism and Disposition July 1994, 22 (4) 530-536;

K

  1. Kemeny, N E

    1. You have access
      Transport limits cellular entry of hepatic arterially injected 5-[18F]fluoro-2'-deoxyuridine in human intrahepatic tumors.
      J R Bading, E R Sigurdson, R D Finn, S D Yeh, J Ginos, N E Kemeny and S M Larson
      Drug Metabolism and Disposition July 1994, 22 (4) 643-650;
  2. Kitareewan, S

    1. You have access
      Genetic and developmental diversity of hepatic cytochromes P450. Warfarin and progesterone metabolism by hepatic microsomes from four inbred strains of rat.
      S Kitareewan and F G Walz
      Drug Metabolism and Disposition July 1994, 22 (4) 607-615;
  3. Krieter, P A

    1. You have access
      Disposition and metabolism of the hypoglycemic agent pioglitazone in rats.
      P A Krieter, A E Colletti, G A Doss and R R Miller
      Drug Metabolism and Disposition July 1994, 22 (4) 625-630;
  4. Kurihara, A

    1. You have access
      Pharmacokinetics of RU44403, an active form of newly developed angiotensin-converting enzyme inhibitor (RU44570) in the rat.
      M Hirayama, A Kurihara, T Manabe and Y Hasegawa
      Drug Metabolism and Disposition July 1994, 22 (4) 601-606;

L

  1. Labarre, P

    1. You have access
      Disposition and metabolism of O6-alkylguanine-DNA alkyltransferase inhibitor in nude mice bearing human melanoma.
      C Cussac, E Mounetou, M Rapp, J C Madelmont, J C Maurizis, P Labarre, P Chollet, J L Chabard, D Godeneche and J P Baudry
      Drug Metabolism and Disposition July 1994, 22 (4) 637-642;
  2. Larson, S M

    1. You have access
      Transport limits cellular entry of hepatic arterially injected 5-[18F]fluoro-2'-deoxyuridine in human intrahepatic tumors.
      J R Bading, E R Sigurdson, R D Finn, S D Yeh, J Ginos, N E Kemeny and S M Larson
      Drug Metabolism and Disposition July 1994, 22 (4) 643-650;
  3. Lau, S S

    1. You have access
      Metabolism and toxicity of 2-bromo-(diglutathion-S-yl)-hydroquinone and 2-bromo-3-(glutathion-S-yl)hydroquinone in the in situ perfused rat kidney.
      M I Rivera, L M Hinojosa, B A Hill, S S Lau and T J Monks
      Drug Metabolism and Disposition July 1994, 22 (4) 503-510;
  4. Lepage, F

    1. You have access
      Metabolic chiral inversion of stiripentol in the rat. I. Mechanistic studies.
      K Zhang, C Tang, M Rashed, D Cui, F Tombret, H Botte, F Lepage, R H Levy and T A Baillie
      Drug Metabolism and Disposition July 1994, 22 (4) 544-553;
    2. You have access
      Metabolic chiral inversion of stiripentol in the rat. II. Influence of route of administration.
      C Tang, K Zhang, F Lepage, R H Levy and T A Baillie
      Drug Metabolism and Disposition July 1994, 22 (4) 554-560;
  5. Levy, R H

    1. You have access
      Metabolic chiral inversion of stiripentol in the rat. I. Mechanistic studies.
      K Zhang, C Tang, M Rashed, D Cui, F Tombret, H Botte, F Lepage, R H Levy and T A Baillie
      Drug Metabolism and Disposition July 1994, 22 (4) 544-553;
    2. You have access
      Metabolic chiral inversion of stiripentol in the rat. II. Influence of route of administration.
      C Tang, K Zhang, F Lepage, R H Levy and T A Baillie
      Drug Metabolism and Disposition July 1994, 22 (4) 554-560;
  6. Li, Y

    1. You have access
      Effects of flavonoids on cytochrome P450-dependent acetaminophen metabolism in rats and human liver microsomes.
      Y Li, E Wang, C J Patten, L Chen and C S Yang
      Drug Metabolism and Disposition July 1994, 22 (4) 566-571;
  7. Loizou, G D

    1. You have access
      Gas-uptake pharmacokinetics of 2,2-dichloro-1,1,1-trifluoroethane (HCFC-123).
      G D Loizou, G Urban, W Dekant and M W Anders
      Drug Metabolism and Disposition July 1994, 22 (4) 511-517;

M

  1. Madelmont, J C

    1. You have access
      Disposition and metabolism of O6-alkylguanine-DNA alkyltransferase inhibitor in nude mice bearing human melanoma.
      C Cussac, E Mounetou, M Rapp, J C Madelmont, J C Maurizis, P Labarre, P Chollet, J L Chabard, D Godeneche and J P Baudry
      Drug Metabolism and Disposition July 1994, 22 (4) 637-642;
  2. Magdalou, J

    1. You have access
      N-glucuronidation reactions. III. Regioselectivity of N-glucuronidation of methylbiphenyl tetrazole, methylbiphenyl triazole, and methylbiphenyl imidazole using human and rat recombinant UDP-glucuronosyltransferases stably expressed in V79 cells.
      S E Huskey, J Magdalou, M Ouzzine, G Siest and S H Chiu
      Drug Metabolism and Disposition July 1994, 22 (4) 659-662;
  3. Manabe, T

    1. You have access
      Pharmacokinetics of RU44403, an active form of newly developed angiotensin-converting enzyme inhibitor (RU44570) in the rat.
      M Hirayama, A Kurihara, T Manabe and Y Hasegawa
      Drug Metabolism and Disposition July 1994, 22 (4) 601-606;
  4. Mannering, G J

    1. You have access
      Induction of murine cytochrome P4503A by the lichen constituents usnic and vulpinic acids.
      G J Mannering and J A Shoeman
      Drug Metabolism and Disposition July 1994, 22 (4) 663-665;
  5. Maurizis, J C

    1. You have access
      Disposition and metabolism of O6-alkylguanine-DNA alkyltransferase inhibitor in nude mice bearing human melanoma.
      C Cussac, E Mounetou, M Rapp, J C Madelmont, J C Maurizis, P Labarre, P Chollet, J L Chabard, D Godeneche and J P Baudry
      Drug Metabolism and Disposition July 1994, 22 (4) 637-642;
  6. Miller, R R

    1. You have access
      Disposition and metabolism of the hypoglycemic agent pioglitazone in rats.
      P A Krieter, A E Colletti, G A Doss and R R Miller
      Drug Metabolism and Disposition July 1994, 22 (4) 625-630;
    2. You have access
      N-glucuronidation reactions. II. Relative N-glucuronidation reactivity of methylbiphenyl tetrazole, methylbiphenyl triazole, and methylbiphenyl imidazole in rat, monkey, and human hepatic microsomes.
      S W Huskey, G A Doss, R R Miller, W R Schoen and S H Chiu
      Drug Metabolism and Disposition July 1994, 22 (4) 651-658;
  7. Monks, T J

    1. You have access
      Metabolism and toxicity of 2-bromo-(diglutathion-S-yl)-hydroquinone and 2-bromo-3-(glutathion-S-yl)hydroquinone in the in situ perfused rat kidney.
      M I Rivera, L M Hinojosa, B A Hill, S S Lau and T J Monks
      Drug Metabolism and Disposition July 1994, 22 (4) 503-510;
  8. Mounetou, E

    1. You have access
      Disposition and metabolism of O6-alkylguanine-DNA alkyltransferase inhibitor in nude mice bearing human melanoma.
      C Cussac, E Mounetou, M Rapp, J C Madelmont, J C Maurizis, P Labarre, P Chollet, J L Chabard, D Godeneche and J P Baudry
      Drug Metabolism and Disposition July 1994, 22 (4) 637-642;

N

  1. Nabeshima, T

    1. You have access
      Alterations in the pharmacokinetics and protein binding of enprofylline in Eisai hyperbilirubinemic rats.
      M Nadai, T Hasegawa, L Wang, O Tagaya and T Nabeshima
      Drug Metabolism and Disposition July 1994, 22 (4) 561-565;
  2. Nadai, M

    1. You have access
      Alterations in the pharmacokinetics and protein binding of enprofylline in Eisai hyperbilirubinemic rats.
      M Nadai, T Hasegawa, L Wang, O Tagaya and T Nabeshima
      Drug Metabolism and Disposition July 1994, 22 (4) 561-565;
  3. Nagata, K

    1. You have access
      Theoretical kinetics of sequential metabolism in vitro. Study of the formation of 16 alpha-hydroxyandrostenedione from testosterone by purified rat P450 2C11.
      K Sugiyama, K Nagata, J R Gillette and J F Darbyshire
      Drug Metabolism and Disposition July 1994, 22 (4) 584-591;
  4. Norton, R L

    1. You have access
      Urinary excretion of chromium by humans following ingestion of chromium picolinate. Implications for biomonitoring.
      M L Gargas, R L Norton, D J Paustenbach and B L Finley
      Drug Metabolism and Disposition July 1994, 22 (4) 522-529;

O

  1. Ouzzine, M

    1. You have access
      N-glucuronidation reactions. III. Regioselectivity of N-glucuronidation of methylbiphenyl tetrazole, methylbiphenyl triazole, and methylbiphenyl imidazole using human and rat recombinant UDP-glucuronosyltransferases stably expressed in V79 cells.
      S E Huskey, J Magdalou, M Ouzzine, G Siest and S H Chiu
      Drug Metabolism and Disposition July 1994, 22 (4) 659-662;

P

  1. Patten, C J

    1. You have access
      Effects of flavonoids on cytochrome P450-dependent acetaminophen metabolism in rats and human liver microsomes.
      Y Li, E Wang, C J Patten, L Chen and C S Yang
      Drug Metabolism and Disposition July 1994, 22 (4) 566-571;
  2. Paustenbach, D J

    1. You have access
      Urinary excretion of chromium by humans following ingestion of chromium picolinate. Implications for biomonitoring.
      M L Gargas, R L Norton, D J Paustenbach and B L Finley
      Drug Metabolism and Disposition July 1994, 22 (4) 522-529;

R

  1. Rapp, M

    1. You have access
      Disposition and metabolism of O6-alkylguanine-DNA alkyltransferase inhibitor in nude mice bearing human melanoma.
      C Cussac, E Mounetou, M Rapp, J C Madelmont, J C Maurizis, P Labarre, P Chollet, J L Chabard, D Godeneche and J P Baudry
      Drug Metabolism and Disposition July 1994, 22 (4) 637-642;
  2. Rashed, M

    1. You have access
      Metabolic chiral inversion of stiripentol in the rat. I. Mechanistic studies.
      K Zhang, C Tang, M Rashed, D Cui, F Tombret, H Botte, F Lepage, R H Levy and T A Baillie
      Drug Metabolism and Disposition July 1994, 22 (4) 544-553;
  3. Rivera, M I

    1. You have access
      Metabolism and toxicity of 2-bromo-(diglutathion-S-yl)-hydroquinone and 2-bromo-3-(glutathion-S-yl)hydroquinone in the in situ perfused rat kidney.
      M I Rivera, L M Hinojosa, B A Hill, S S Lau and T J Monks
      Drug Metabolism and Disposition July 1994, 22 (4) 503-510;

S

  1. Sanders, R A

    1. You have access
      Chronic voluntary exercise may alter hepatobiliary clearance of endogenous and exogenous chemicals in rats.
      J B Watkins, S T Crawford and R A Sanders
      Drug Metabolism and Disposition July 1994, 22 (4) 537-543;
  2. Schoen, W R

    1. You have access
      N-glucuronidation reactions. II. Relative N-glucuronidation reactivity of methylbiphenyl tetrazole, methylbiphenyl triazole, and methylbiphenyl imidazole in rat, monkey, and human hepatic microsomes.
      S W Huskey, G A Doss, R R Miller, W R Schoen and S H Chiu
      Drug Metabolism and Disposition July 1994, 22 (4) 651-658;
  3. Shoeman, J A

    1. You have access
      Induction of murine cytochrome P4503A by the lichen constituents usnic and vulpinic acids.
      G J Mannering and J A Shoeman
      Drug Metabolism and Disposition July 1994, 22 (4) 663-665;
  4. Siest, G

    1. You have access
      N-glucuronidation reactions. III. Regioselectivity of N-glucuronidation of methylbiphenyl tetrazole, methylbiphenyl triazole, and methylbiphenyl imidazole using human and rat recombinant UDP-glucuronosyltransferases stably expressed in V79 cells.
      S E Huskey, J Magdalou, M Ouzzine, G Siest and S H Chiu
      Drug Metabolism and Disposition July 1994, 22 (4) 659-662;
  5. Sigurdson, E R

    1. You have access
      Transport limits cellular entry of hepatic arterially injected 5-[18F]fluoro-2'-deoxyuridine in human intrahepatic tumors.
      J R Bading, E R Sigurdson, R D Finn, S D Yeh, J Ginos, N E Kemeny and S M Larson
      Drug Metabolism and Disposition July 1994, 22 (4) 643-650;
  6. Sugiyama, K

    1. You have access
      Theoretical kinetics of sequential metabolism in vitro. Study of the formation of 16 alpha-hydroxyandrostenedione from testosterone by purified rat P450 2C11.
      K Sugiyama, K Nagata, J R Gillette and J F Darbyshire
      Drug Metabolism and Disposition July 1994, 22 (4) 584-591;
  7. Svensson, C K

    1. You have access
      Evidence that the biotransformation of dapsone and monoacetyldapsone to their respective hydroxylamine metabolites in rat liver microsomes is mediated by cytochrome P450 2C6/2C11 and 3A1.
      C Vage and C K Svensson
      Drug Metabolism and Disposition July 1994, 22 (4) 572-577;

T

  1. Tagaya, O

    1. You have access
      Alterations in the pharmacokinetics and protein binding of enprofylline in Eisai hyperbilirubinemic rats.
      M Nadai, T Hasegawa, L Wang, O Tagaya and T Nabeshima
      Drug Metabolism and Disposition July 1994, 22 (4) 561-565;
  2. Tam, Y K

    1. You have access
      Kinetic interactions of lidocaine, diphenhydramine, and verapamil with diltiazem. A study using isolated perfused rat liver.
      M D Hussain, Y K Tam, M R Gray and R T Coutts
      Drug Metabolism and Disposition July 1994, 22 (4) 530-536;
  3. Tang, C

    1. You have access
      Metabolic chiral inversion of stiripentol in the rat. I. Mechanistic studies.
      K Zhang, C Tang, M Rashed, D Cui, F Tombret, H Botte, F Lepage, R H Levy and T A Baillie
      Drug Metabolism and Disposition July 1994, 22 (4) 544-553;
    2. You have access
      Metabolic chiral inversion of stiripentol in the rat. II. Influence of route of administration.
      C Tang, K Zhang, F Lepage, R H Levy and T A Baillie
      Drug Metabolism and Disposition July 1994, 22 (4) 554-560;
  4. Tombret, F

    1. You have access
      Metabolic chiral inversion of stiripentol in the rat. I. Mechanistic studies.
      K Zhang, C Tang, M Rashed, D Cui, F Tombret, H Botte, F Lepage, R H Levy and T A Baillie
      Drug Metabolism and Disposition July 1994, 22 (4) 544-553;
  5. Tsai, T H

    1. You have access
      Disposition of magnolol after intravenous bolus and infusion in rabbits.
      T H Tsai, C J Chou and C F Chen
      Drug Metabolism and Disposition July 1994, 22 (4) 518-521;
  6. Tulliez, J

    1. You have access
      Evidence for new metabolic pathways of chloramphenicol in the duck.
      J P Cravedi, M Baradat, L Debrauwer, J Alary, J Tulliez and G Bories
      Drug Metabolism and Disposition July 1994, 22 (4) 578-583;

U

  1. Urban, G

    1. You have access
      Gas-uptake pharmacokinetics of 2,2-dichloro-1,1,1-trifluoroethane (HCFC-123).
      G D Loizou, G Urban, W Dekant and M W Anders
      Drug Metabolism and Disposition July 1994, 22 (4) 511-517;

V

  1. Vage, C

    1. You have access
      Evidence that the biotransformation of dapsone and monoacetyldapsone to their respective hydroxylamine metabolites in rat liver microsomes is mediated by cytochrome P450 2C6/2C11 and 3A1.
      C Vage and C K Svensson
      Drug Metabolism and Disposition July 1994, 22 (4) 572-577;
  2. Vickers, S

    1. You have access
      Disposition of MK-852, a fibrinogen receptor antagonist, in rats and dogs.
      S Vickers, C A Duncan, A S Yuan and K P Vyas
      Drug Metabolism and Disposition July 1994, 22 (4) 631-636;
  3. Vyas, K P

    1. You have access
      Disposition of MK-852, a fibrinogen receptor antagonist, in rats and dogs.
      S Vickers, C A Duncan, A S Yuan and K P Vyas
      Drug Metabolism and Disposition July 1994, 22 (4) 631-636;

W

  1. Walz, F G

    1. You have access
      Genetic and developmental diversity of hepatic cytochromes P450. Warfarin and progesterone metabolism by hepatic microsomes from four inbred strains of rat.
      S Kitareewan and F G Walz
      Drug Metabolism and Disposition July 1994, 22 (4) 607-615;
  2. Wang, E

    1. You have access
      Effects of flavonoids on cytochrome P450-dependent acetaminophen metabolism in rats and human liver microsomes.
      Y Li, E Wang, C J Patten, L Chen and C S Yang
      Drug Metabolism and Disposition July 1994, 22 (4) 566-571;
  3. Wang, L

    1. You have access
      Alterations in the pharmacokinetics and protein binding of enprofylline in Eisai hyperbilirubinemic rats.
      M Nadai, T Hasegawa, L Wang, O Tagaya and T Nabeshima
      Drug Metabolism and Disposition July 1994, 22 (4) 561-565;
  4. Watkins, J B

    1. You have access
      Chronic voluntary exercise may alter hepatobiliary clearance of endogenous and exogenous chemicals in rats.
      J B Watkins, S T Crawford and R A Sanders
      Drug Metabolism and Disposition July 1994, 22 (4) 537-543;

Y

  1. Yamaguchi, T

    1. You have access
      Metabolic fate of [3H]-l-menthol in the rat.
      T Yamaguchi, J Caldwell and P B Farmer
      Drug Metabolism and Disposition July 1994, 22 (4) 616-624;
  2. Yang, C S

    1. You have access
      Effects of flavonoids on cytochrome P450-dependent acetaminophen metabolism in rats and human liver microsomes.
      Y Li, E Wang, C J Patten, L Chen and C S Yang
      Drug Metabolism and Disposition July 1994, 22 (4) 566-571;
  3. Yeh, S D

    1. You have access
      Transport limits cellular entry of hepatic arterially injected 5-[18F]fluoro-2'-deoxyuridine in human intrahepatic tumors.
      J R Bading, E R Sigurdson, R D Finn, S D Yeh, J Ginos, N E Kemeny and S M Larson
      Drug Metabolism and Disposition July 1994, 22 (4) 643-650;
  4. Yuan, A S

    1. You have access
      Disposition of MK-852, a fibrinogen receptor antagonist, in rats and dogs.
      S Vickers, C A Duncan, A S Yuan and K P Vyas
      Drug Metabolism and Disposition July 1994, 22 (4) 631-636;

Z

  1. Zhang, K

    1. You have access
      Metabolic chiral inversion of stiripentol in the rat. I. Mechanistic studies.
      K Zhang, C Tang, M Rashed, D Cui, F Tombret, H Botte, F Lepage, R H Levy and T A Baillie
      Drug Metabolism and Disposition July 1994, 22 (4) 544-553;
    2. You have access
      Metabolic chiral inversion of stiripentol in the rat. II. Influence of route of administration.
      C Tang, K Zhang, F Lepage, R H Levy and T A Baillie
      Drug Metabolism and Disposition July 1994, 22 (4) 554-560;
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In this issue

Drug Metabolism and Disposition
Vol. 22, Issue 4
1 Jul 1994
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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