Drug Metabolism and Disposition: 22 (5)

September 01, 1994; Volume 22,Issue 5

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Role of cytochrome P450 2E1 in the metabolism of 1,1,2,3,3,3-hexafluoropropyl methyl ether.
U Köster, P Speerschneider, R Kerssebaum, H Wittmann and W Dekant

Drug Metabolism and Disposition September 1994, 22 (5) 667-672;
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1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) modulates rat liver microsomal cyclophosphamide and ifosphamide activation by suppressing cytochrome P450 2C11 messenger RNA levels.
T K Chang, H Chen and D J Waxman

Drug Metabolism and Disposition September 1994, 22 (5) 673-679;
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Role of Kupffer cells in storage and metabolism of benzo(a)pyrene in the liver.
Z Zhong, M Goto, T Hijioka, H Oide, F C Kauffman and R G Thurman

Drug Metabolism and Disposition September 1994, 22 (5) 680-687;
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cDNA-directed expression of human cytochrome P450 CYP3A4 using baculovirus.
J T Buters, K R Korzekwa, K L Kunze, Y Omata, J P Hardwick and F J Gonzalez

Drug Metabolism and Disposition September 1994, 22 (5) 688-692;
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Physiological disposition of L-663,581, a partial agonist of the benzodiazepine receptor, in laboratory animals.
I W Chen and J H Lin

Drug Metabolism and Disposition September 1994, 22 (5) 693-699;
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Oxidation of R(+)- and S(-)-carvedilol by rat liver microsomes. Evidence for stereoselective oxidation and characterization of the cytochrome P450 isozymes involved.
M Fujimaki

Drug Metabolism and Disposition September 1994, 22 (5) 700-708;
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Pharmacokinetics of HIV protease inhibitor DMP 323 in rats and dogs.
M F Grubb, Y N Wong, D L Burcham, P L Saxton, C Y Quon and S M Huang

Drug Metabolism and Disposition September 1994, 22 (5) 709-712;
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Studies on the glucuronidation of dopamine D-1 receptor antagonists, SCH 39166 and SCH 23390, by human liver microsomes.
T R Tephly, B Coffman, P Styczynski, G Rios, D M Charkowski, M Vanrollins, R D McQuade and C E Tedford

Drug Metabolism and Disposition September 1994, 22 (5) 713-718;
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Stereoselective hydroxylation of tacrine in rats and humans.
W D Hooper, W F Pool, T F Woolf and J Gal

Drug Metabolism and Disposition September 1994, 22 (5) 719-724;
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Sulfation of acetaminophen and acetaminophen-induced alterations in sulfate and 3'-phosphoadenosine 5'-phosphosulfate homeostasis in rats with deficient dietary intake of sulfur.
Z Gregus, H J Kim, C Madhu, Y Liu, P Rozman and C D Klaassen

Drug Metabolism and Disposition September 1994, 22 (5) 725-730;
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Detoxication of the 2',3'-epoxide metabolites of allylbenzene and estragole. Conjugation with glutathione.
G Luo and T M Guenthner

Drug Metabolism and Disposition September 1994, 22 (5) 731-737;
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Novel carbamate metabolites of mofegiline, a primary amine monoamine oxidase B inhibitor, in dogs and humans.
J Dow, F Piriou, E Wolf, B D Dulery and K D Haegele

Drug Metabolism and Disposition September 1994, 22 (5) 738-749;
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Formation of toxic metabolites from thiabendazole and other thiazoles in mice. Identification of thioamides as ring cleavage products.
T Mizutani, K Yoshida and S Kawazoe

Drug Metabolism and Disposition September 1994, 22 (5) 750-755;
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Metabolism of methoxyphenamine in vitro by a CYP2D6 microsomal preparation.
R T Coutts, O O Bolaji, P Su and G B Baker

Drug Metabolism and Disposition September 1994, 22 (5) 756-760;
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Inter-individual differences of 4-[4-(4-methylphenyl)-phenylmethoxy-1-piperidinyl]butyric acid disposition in rats: possible involvement of genetic polymorphism.
E Takahara, O Nagata, H Kato, S Ohta and M Hirobe

Drug Metabolism and Disposition September 1994, 22 (5) 761-769;
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Pharmacokinetics of dapsone and amino acid prodrugs of dapsone.
N L Pochopin, W N Charman and V J Stella

Drug Metabolism and Disposition September 1994, 22 (5) 770-775;
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Effects of diltiazem on the disposition and metabolism of the enantiomers of propranolol in the dog during multiple oral dosing.
S M Lankford, C Maskasame and S A Bai

Drug Metabolism and Disposition September 1994, 22 (5) 776-787;
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The in vitro hepatic metabolism of ABT-418, a cholinergic channel activator, in rats, dogs, cynomolgus monkeys, and humans.
A D Rodrigues, J L Ferrero, M T Amann, G A Rotert, S P Cepa, B W Surber, J M Machinist, N R Tich, J P Sullivan and D S Garvey

Drug Metabolism and Disposition September 1994, 22 (5) 788-798;
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Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates.
M D Green, E M Oturu and T R Tephly

Drug Metabolism and Disposition September 1994, 22 (5) 799-805;
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Inhibition of p-nitrophenol hydroxylase in rat liver microsomes by small aromatic and heterocyclic molecules.
M B Hargreaves, B C Jones, D A Smith and A Gescher

Drug Metabolism and Disposition September 1994, 22 (5) 806-810;
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FK 506 metabolism in human liver microsomes: investigation of the involvement of cytochrome P450 isozymes other than CYP3A4.
B V Karanam, S H Vincent, D J Newton, R W Wang and S H Chiu

Drug Metabolism and Disposition September 1994, 22 (5) 811-814;
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Carbonyl reduction of 6-tert-butyl-2,3-epoxy-1,4-benzoquinone, a metabolite of 3-tert-butyl-4-hydroxyanisole, by rat liver microsomes and cytosol.
K Tajima, M Hashizaki, K Yamamoto and T Mizutani

Drug Metabolism and Disposition September 1994, 22 (5) 815-818;

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