Drug Metabolism and Disposition: 22 (6)

November 01, 1994; Volume 22,Issue 6

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Solvolysis of butadiene monoxide.
I Linhart

Drug Metabolism and Disposition November 1994, 22 (6) 820-821;
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Propranolol disposition in the single-pass isolated, perfused rat liver in the presence and absence of insulin and glucagon.
H A Semple and F Xia

Drug Metabolism and Disposition November 1994, 22 (6) 822-826;
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Theophylline N-demethylations as probes for P4501A1 and P4501A2.
M A Sarkar and B J Jackson

Drug Metabolism and Disposition November 1994, 22 (6) 827-834;
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Stereoselective pharmacokinetics of L-buthionine SR-sulfoximine in patients with cancer.
F P Lacreta, J M Brennan, T C Hamilton, R F Ozols and P J O'Dwyer

Drug Metabolism and Disposition November 1994, 22 (6) 835-842;
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Pharmcokinetics in healthy volunteers and patients of NAc-SDKP (seraspenide), a negative regulator of hematopoiesis.
E Ezan, P Carde, J Le Kerneau, T Ardouin, F Thomas, F Isnard, E Deschamps de Paillette and J M Grognet

Drug Metabolism and Disposition November 1994, 22 (6) 843-848;
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Terfenadine metabolism in human liver. In vitro inhibition by macrolide antibiotics and azole antifungals.
M Jurima-Romet, K Crawford, T Cyr and T Inaba

Drug Metabolism and Disposition November 1994, 22 (6) 849-857;
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A comprehensive evaluation of the vial equilibration method for quantification of the metabolism of volatile organic chemicals. Trichloroethylene.
C Kim, R O Manning, R P Brown and J V Bruckner

Drug Metabolism and Disposition November 1994, 22 (6) 858-865;
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Urinary metabolites of (R),(R)-labetalol.
K B Alton, T M Chan and B N Pramanik

Drug Metabolism and Disposition November 1994, 22 (6) 866-872;
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Pharmacokinetics and metabolism of cyclosporin G in humans.
J B Mangold, H F Schran and F L Tse

Drug Metabolism and Disposition November 1994, 22 (6) 873-879;
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The orally active renin inhibitor A-74273. In vivo and in vitro morpholine ring metabolism in rats, dogs, and humans.
J F Denissen, B A Grabowski, M K Johnson, S A Boyd, J T Uchic, H Stein, S Cepa and P Hill

Drug Metabolism and Disposition November 1994, 22 (6) 880-888;
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Species differences in the induction of hepatic microsomal carboxylesterases caused by dietary exposure to di(2-ethylhexyl)phthalate, a peroxisome proliferator.
M Hosokawa, K Hirata, F Nakata, T Suga and T Satoh

Drug Metabolism and Disposition November 1994, 22 (6) 889-894;
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Metabolic pathways of WR-2721 (ethyol, amifostine) in the BALB/c mouse.
L M Shaw, H S Bonner and D Q Brown

Drug Metabolism and Disposition November 1994, 22 (6) 895-902;
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Hepatic metabolism of spironolactone. Production of 3-hydroxy-thiomethyl metabolites.
L E Los, S M Pitzenberger, H G Ramjit, A B Coddington and H D Colby

Drug Metabolism and Disposition November 1994, 22 (6) 903-908;
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Cytochrome P450 isozymes involved in propranolol metabolism in human liver microsomes. The role of CYP2D6 as ring-hydroxylase and CYP1A2 as N-desisopropylase.
Y Masubuchi, S Hosokawa, T Horie, T Suzuki, S Ohmori, M Kitada and S Narimatsu

Drug Metabolism and Disposition November 1994, 22 (6) 909-915;
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In vitro metabolism of dorzolamide, a novel potent carbonic anhydrase inhibitor, in rat liver microsomes.
T Hasegawa, K Hara, T Kenmochi and S Hata

Drug Metabolism and Disposition November 1994, 22 (6) 916-921;
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Glucuronidation of N-acetylbenzidine by human liver.
S R Babu, V M Lakshmi, T V Zenser and B B Davis

Drug Metabolism and Disposition November 1994, 22 (6) 922-927;
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Identification of 9,13-dicis-retinoic acid as a major plasma metabolite of 9-cis-retinoic acid and limited transfer of 9-cis-retinoic acid and 9,13-dicis-retinoic acid to the mouse and rat embryos.
G Tzimas, J O Sass, W Wittfoht, M M Elmazar, K Ehlers and H Nau

Drug Metabolism and Disposition November 1994, 22 (6) 928-936;
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Metabolism of the proestrogenic pesticide methoxychlor by hepatic P450 monooxygenases in rats and humans. Dual pathways involving novel ortho ring-hydroxylation by CYP2B.
S S Dehal and D Kupfer

Drug Metabolism and Disposition November 1994, 22 (6) 937-946;
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Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test.
K S Lown, J C Kolars, K E Thummel, J L Barnett, K L Kunze, S A Wrighton and P B Watkins

Drug Metabolism and Disposition November 1994, 22 (6) 947-955;
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Mechanism of covalent adduct formation of diclofenac to rat hepatic microsomal proteins. Retention of the glucuronic acid moiety in the adduct.
A Kretz-Rommel and U A Boelsterli

Drug Metabolism and Disposition November 1994, 22 (6) 956-961;
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Identification of hepatocytes as the major locus of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1-related P450s, TCDDAA and TCDDAHH, in chick embryo liver.
L Paroli, C Lee and A B Rifkind

Drug Metabolism and Disposition November 1994, 22 (6) 962-968;
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Increased cosedimentation of cytosolic glutathione S-transferases with microsomal fractions prepared from frozen rat liver.
A E Cribb, G P Griffin, S P Spielberg, T H Rushmore, N Chauret and D A Nicoll-Griffith

Drug Metabolism and Disposition November 1994, 22 (6) 969-972;
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Tissue distribution and stereoselectivity of remacemide-glycine hydrolase.
H Heyn, Y G Bankmann and M W Anders

Drug Metabolism and Disposition November 1994, 22 (6) 973-974;
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Relationships between the levels of cytochrome P4502C9 and its prototypic catalytic activities in human liver microsomes.
S D Hall, M A Hamman, A E Rettie, L C Wienkers, W F Trager, M Vandenbranden and S A Wrighton

Drug Metabolism and Disposition November 1994, 22 (6) 975-978;

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