Drug Metabolism and Disposition: 23 (1)

January 01, 1995; Volume 23,Issue 1

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Metabolism of a candidate 8-aminoquinoline antimalarial agent, WR 238605, by rat liver microsomes.
O R Idowu, J O Peggins, T G Brewer and C Kelley

Drug Metabolism and Disposition January 1995, 23 (1) 1-17;
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Side-chain hydroxylation in the metabolism of 8-aminoquinoline antiparasitic agents.
O R Idowu, J O Peggins and T G Brewer

Drug Metabolism and Disposition January 1995, 23 (1) 18-27;
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Further metabolism of FK506 (tacrolimus). Identification and biological activities of the metabolites oxidized at multiple sites of FK506.
K Iwasaki, T Shiraga, H Matsuda, K Nagase, Y Tokuma, T Hata, Y Fujii, S Sakuma, T Fujitsu and A Fujikawa

Drug Metabolism and Disposition January 1995, 23 (1) 28-34;
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Ocular absorption, distribution, and systemic absorption of a novel antiglaucoma medication, prostaglandin derivative, in male white rabbits.
K Higaki, K Kamata, M Takeuchi, K Inazawa, T Chikai, T Hamaguchi, T Yukawa, K Kadono, S Kawahara and M Nakano

Drug Metabolism and Disposition January 1995, 23 (1) 35-43;
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Infection (Actinobacillus pleuropneumoniae)-mediated suppression of oxidative hepatic drug metabolism and cytochrome P4503A mRNA levels in pigs.
M Monshouwer, R F Witkamp, S M Nijmeijer, L A Van Leengoed, J H Verheijden and A S Van Miert

Drug Metabolism and Disposition January 1995, 23 (1) 44-47;
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Biosynthesis of S-(2-chloro-1,1,2-trifluoroethyl)glutathione in rat and human hepatocytes and in Hep G2 cells.
E Tanaka and M W Anders

Drug Metabolism and Disposition January 1995, 23 (1) 48-54;
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Pharmacokinetics and organ clearance of a 3'-biotinylated, internally [32P]-labeled phosphodiester oligodeoxynucleotide coupled to a neutral avidin/monoclonal antibody conjugate.
Y S Kang, R J Boado and W M Pardridge

Drug Metabolism and Disposition January 1995, 23 (1) 55-59;
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Isoflurane-chlorodifluoroethene interaction in human liver microsomes. Role of cytochrome P4502B6 in potentiation of haloethene metabolism.
M T Baker, M J Olson, Y Wang, W C Ronnenberg, J T Johnson and A N Brady

Drug Metabolism and Disposition January 1995, 23 (1) 60-64;
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In vitro and in vivo biotransformations of the naphthalenic lignan lactone 5-lipoxygenase inhibitor, L-702,539.
N Chauret, C Li, Y Ducharme, L A Trimble, J A Yergey, C Ramachandran and D A Nicoll-Griffith

Drug Metabolism and Disposition January 1995, 23 (1) 65-71;
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Xenopus laevis: a model system for the study of embryonic retinoid metabolism. I. Embryonic metabolism of 9-cis- and all-trans-retinals and retinols to their corresponding acid forms.
J C Kraft, D Kimelman and M R Juchau

Drug Metabolism and Disposition January 1995, 23 (1) 72-82;
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Xenopus laevis: a model system for the study of embryonic retinoid metabolism. II. Embryonic metabolism of all-trans-3,4-didehydroretinol to all-trans-3,4-didehydroretinoic acid.
J Creech Kraft, D Kimelman and M R Juchau

Drug Metabolism and Disposition January 1995, 23 (1) 83-89;
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Pharmacokinetics and bioavailability of topiramate in the beagle dog.
A J Streeter, P L Stahle, M L Holland, J F Pritchard and A R Takacs

Drug Metabolism and Disposition January 1995, 23 (1) 90-93;
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Biotransformation of CI-937 in primary cultures of rat hepatocytes. Formation of glutathione conjugates.
U Renner, J Blanz, S Freund, D Waidelich, G Ehninger and K P Zeller

Drug Metabolism and Disposition January 1995, 23 (1) 94-101;
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Identification and quantification of fluorine-containing metabolites of 1-chloro-2,2,2-trifluoroethane (HCFC133A) in the rat by 19F-NMR spectroscopy.
M K Ellis, J L Naylor, T Green and M A Collins

Drug Metabolism and Disposition January 1995, 23 (1) 102-106;
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Metabolism of the nephrotoxicant N-(3,5-dichlorophenyl)succinimide by isolated rat hepatocytes.
A K Nyarko and P J Harvison

Drug Metabolism and Disposition January 1995, 23 (1) 107-112;
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Fate of 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (ET18-OME) in malignant cells, normal cells, and isolated and perfused rat liver.
A Magistrelli, P Villa, E Benfenati, E J Modest, M Salmona and M T Tacconi

Drug Metabolism and Disposition January 1995, 23 (1) 113-118;
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Characterization and formation of the glutathione conjugate of clofibric acid.
L J Shore, C Fenselau, A R King and R G Dickinson

Drug Metabolism and Disposition January 1995, 23 (1) 119-123;
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Metabolism of [14C]- and [35S]S-(1,2-dichlorovinyl)-L-cysteine in the male Fischer 344 rat.
M B Finkelstein, N J Patel and M W Anders

Drug Metabolism and Disposition January 1995, 23 (1) 124-128;
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Metabolism of [14C]naphthalene in the B6C3F1 murine isolated perfused liver.
L S Tsuruda, M W Lamé and A D Jones

Drug Metabolism and Disposition January 1995, 23 (1) 129-136;
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Budesonide is metabolized by cytochrome P450 3A (CYP3A) enzymes in human liver.
G Jönsson, A Aström and P Andersson

Drug Metabolism and Disposition January 1995, 23 (1) 137-142;
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Nicotine and cotinine accumulation in pigmented and unpigmented rat hair.
B Gerstenberg, G Schepers, P Voncken and H Völkel

Drug Metabolism and Disposition January 1995, 23 (1) 143-148;
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Stereoselective glucuronidation of zileuton isomers by human hepatic microsomes.
D J Sweeny and H N Nellans

Drug Metabolism and Disposition January 1995, 23 (1) 149-153;
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Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
D J Newton, R W Wang and A Y Lu

Drug Metabolism and Disposition January 1995, 23 (1) 154-158;

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