Drug Metabolism and Disposition: 23 (10)

October 01, 1995; Volume 23,Issue 10

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Use of gender and oxygenation as synonyms for sex and oxidation.
S Vickers

Drug Metabolism and Disposition October 1995, 23 (10) 1007;
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Species similarities and differences in pharmacokinetics.
J H Lin

Drug Metabolism and Disposition October 1995, 23 (10) 1008-1021;
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Interindividual variation in carboxylesterase levels in human liver microsomes.
M Hosokawa, T Endo, M Fujisawa, S Hara, N Iwata, Y Sato and T Satoh

Drug Metabolism and Disposition October 1995, 23 (10) 1022-1027;
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Preclinical pharmacokinetic evaluation of the respiratory syncytial virus-specific reshaped human monoclonal antibody RSHZ19.
C B Davis, T W Hepburn, J J Urbanski, D C Kwok, T K Hart, D J Herzyk, S G Demuth, M Leland and G R Rhodes

Drug Metabolism and Disposition October 1995, 23 (10) 1028-1036;
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Human liver lauric acid hydroxylase activities.
P J Castle, J L Merdink, J R Okita, S A Wrighton and R T Okita

Drug Metabolism and Disposition October 1995, 23 (10) 1037-1043;
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Renal catabolism of recombinant human soluble CD4 after intravenous administration to male Sprague-Dawley rats.
T W Hepburn, C B Davis, J J Urbanski, B R Smith, W H Schaefer, M A Carbonaro and P J Bugelski

Drug Metabolism and Disposition October 1995, 23 (10) 1044-1050;
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Metabolism of mofarotene in hepatocytes and liver microsomes from different species. Comparison with in vivo data and evaluation of the cytochrome P450 isoenzymes involved in human biotransformation.
B Valles, C D Schiller, P Coassolo, G De Sousa, R Wyss, D Jaeck, A Viger-Chougnet and R Rahmani

Drug Metabolism and Disposition October 1995, 23 (10) 1051-1057;
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Xenopus laevis: a model system for the study of embryonic retinoid metabolism. III. Isomerization and metabolism of all-trans-retinoic acid and 9-cis-retinoic acid and their dysmorphogenic effects in embryos during neurulation.
J C Kraft and M R Juchau

Drug Metabolism and Disposition October 1995, 23 (10) 1058-1071;
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Microdialysis sampling for hepatic metabolism studies. Impact of microdialysis probe design and implantation technique on liver tissue.
M I Davies and C E Lunte

Drug Metabolism and Disposition October 1995, 23 (10) 1072-1079;
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Human breast adenocarcinoma MCF-7/0 cells electroporated with cytosolic class 3 aldehyde dehydrogenases obtained from tumor cells and a normal tissue exhibit differential sensitivity to mafosfamide.
L Sreerama and N E Sladek

Drug Metabolism and Disposition October 1995, 23 (10) 1080-1084;
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Verlukast (MK-0679) conjugation with glutathione by rat liver and kidney cytosols and excretion in the bile.
D A Nicoll-Griffith, N Gupta, S P Twa, H Williams, L A Trimble and J A Yergey

Drug Metabolism and Disposition October 1995, 23 (10) 1085-1093;
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Minimal effects of two aldose reductase inhibitors, AL-1576 and AL-4114, after subacute topical-ocular dosing on xenobiotic biotransformation in rabbits.
S G Sastry, R A Sanders, J C Veltman and J B Watkins

Drug Metabolism and Disposition October 1995, 23 (10) 1094-1098;
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Stereoselective disposition of naproxen glucuronide in the rat.
M Iwaki, A Bischer, A C Nguyen, A F McDonagh and L Z Benet

Drug Metabolism and Disposition October 1995, 23 (10) 1099-1103;
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Disposition of DMP 811 (L-708,404), a potent angiotensin II receptor antagonist, in the rat, monkey, and chimpanzee.
K E Zhang and K P Vyas

Drug Metabolism and Disposition October 1995, 23 (10) 1104-1109;
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Liver volume as a determinant of drug clearance in children and adolescents.
D J Murry, W R Crom, W E Reddick, R Bhargava and W E Evans

Drug Metabolism and Disposition October 1995, 23 (10) 1110-1116;
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Metabolism and pharmacokinetics of N1,N11-diethylnorspermine.
R J Bergeron, W R Weimar, G Luchetta, R R Streiff, J Wiegand, J Perrin, K M Schreier, C Porter, G W Yao and H Dimova

Drug Metabolism and Disposition October 1995, 23 (10) 1117-1125;
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Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride.
S W Huskey, D C Dean, R R Miller, G H Rasmusson and S H Chiu

Drug Metabolism and Disposition October 1995, 23 (10) 1126-1135;
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Metabolism as a determinant of species susceptibility to 2,3,5-(triglutathion-S-yl)hydroquinone-mediated nephrotoxicity. The role of N-acetylation and N-deacetylation.
S S Lau, H E Kleiner and T J Monks

Drug Metabolism and Disposition October 1995, 23 (10) 1136-1142;
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In vitro hepatic metabolism of ABT-418 in chimpanzee (Pan troglodytes). A unique pattern of microsomal flavin-containing monooxygenase-dependent stereoselective N'-oxidation.
A D Rodrigues, M J Kukulka, J L Ferrero and J R Cashman

Drug Metabolism and Disposition October 1995, 23 (10) 1143-1152;
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Identification of the human and rat P450 enzymes responsible for the sulfoxidation of S-methyl N,N-diethylthiolcarbamate (DETC-ME). The terminal step in the bioactivation of disulfiram.
A Madan, A Parkinson and M D Faiman

Drug Metabolism and Disposition October 1995, 23 (10) 1153-1162;
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Identification of the human liver cytochrome P450 enzymes involved in the metabolism of zileuton (ABT-077) and its N-dehydroxylated metabolite, Abbott-66193.
J M Machinist, M D Mayer, M S Shet, J L Ferrero and A D Rodrigues

Drug Metabolism and Disposition October 1995, 23 (10) 1163-1174;
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Determination of nicotine metabolites in rat brain after peripheral radiolabeled nicotine administration: detection of nornicotine.
P A Crooks, M Li and L P Dwoskin

Drug Metabolism and Disposition October 1995, 23 (10) 1175-1177;
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Influence of lipophilicity on the bioavailability and disposition of orally active 3-hydroxypyridin-4-one metal chelators.
R A Yokel, A M Fredenburg, K A Meurer and T L Skinner

Drug Metabolism and Disposition October 1995, 23 (10) 1178-1180;

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