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Drug Metabolism & Disposition

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Table of Contents

October 01, 1995; Volume 23,Issue 10
  • You have access
    Use of gender and oxygenation as synonyms for sex and oxidation.
    S Vickers
    Drug Metabolism and Disposition October 1995, 23 (10) 1007;
  • You have access
    Species similarities and differences in pharmacokinetics.
    J H Lin
    Drug Metabolism and Disposition October 1995, 23 (10) 1008-1021;
  • You have access
    Interindividual variation in carboxylesterase levels in human liver microsomes.
    M Hosokawa, T Endo, M Fujisawa, S Hara, N Iwata, Y Sato and T Satoh
    Drug Metabolism and Disposition October 1995, 23 (10) 1022-1027;
  • You have access
    Preclinical pharmacokinetic evaluation of the respiratory syncytial virus-specific reshaped human monoclonal antibody RSHZ19.
    C B Davis, T W Hepburn, J J Urbanski, D C Kwok, T K Hart, D J Herzyk, S G Demuth, M Leland and G R Rhodes
    Drug Metabolism and Disposition October 1995, 23 (10) 1028-1036;
  • You have access
    Human liver lauric acid hydroxylase activities.
    P J Castle, J L Merdink, J R Okita, S A Wrighton and R T Okita
    Drug Metabolism and Disposition October 1995, 23 (10) 1037-1043;
  • You have access
    Renal catabolism of recombinant human soluble CD4 after intravenous administration to male Sprague-Dawley rats.
    T W Hepburn, C B Davis, J J Urbanski, B R Smith, W H Schaefer, M A Carbonaro and P J Bugelski
    Drug Metabolism and Disposition October 1995, 23 (10) 1044-1050;
  • You have access
    Metabolism of mofarotene in hepatocytes and liver microsomes from different species. Comparison with in vivo data and evaluation of the cytochrome P450 isoenzymes involved in human biotransformation.
    B Valles, C D Schiller, P Coassolo, G De Sousa, R Wyss, D Jaeck, A Viger-Chougnet and R Rahmani
    Drug Metabolism and Disposition October 1995, 23 (10) 1051-1057;
  • You have access
    Xenopus laevis: a model system for the study of embryonic retinoid metabolism. III. Isomerization and metabolism of all-trans-retinoic acid and 9-cis-retinoic acid and their dysmorphogenic effects in embryos during neurulation.
    J C Kraft and M R Juchau
    Drug Metabolism and Disposition October 1995, 23 (10) 1058-1071;
  • You have access
    Microdialysis sampling for hepatic metabolism studies. Impact of microdialysis probe design and implantation technique on liver tissue.
    M I Davies and C E Lunte
    Drug Metabolism and Disposition October 1995, 23 (10) 1072-1079;
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    Human breast adenocarcinoma MCF-7/0 cells electroporated with cytosolic class 3 aldehyde dehydrogenases obtained from tumor cells and a normal tissue exhibit differential sensitivity to mafosfamide.
    L Sreerama and N E Sladek
    Drug Metabolism and Disposition October 1995, 23 (10) 1080-1084;
  • You have access
    Verlukast (MK-0679) conjugation with glutathione by rat liver and kidney cytosols and excretion in the bile.
    D A Nicoll-Griffith, N Gupta, S P Twa, H Williams, L A Trimble and J A Yergey
    Drug Metabolism and Disposition October 1995, 23 (10) 1085-1093;
  • You have access
    Minimal effects of two aldose reductase inhibitors, AL-1576 and AL-4114, after subacute topical-ocular dosing on xenobiotic biotransformation in rabbits.
    S G Sastry, R A Sanders, J C Veltman and J B Watkins
    Drug Metabolism and Disposition October 1995, 23 (10) 1094-1098;
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    Stereoselective disposition of naproxen glucuronide in the rat.
    M Iwaki, A Bischer, A C Nguyen, A F McDonagh and L Z Benet
    Drug Metabolism and Disposition October 1995, 23 (10) 1099-1103;
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    Disposition of DMP 811 (L-708,404), a potent angiotensin II receptor antagonist, in the rat, monkey, and chimpanzee.
    K E Zhang and K P Vyas
    Drug Metabolism and Disposition October 1995, 23 (10) 1104-1109;
  • You have access
    Liver volume as a determinant of drug clearance in children and adolescents.
    D J Murry, W R Crom, W E Reddick, R Bhargava and W E Evans
    Drug Metabolism and Disposition October 1995, 23 (10) 1110-1116;
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    Metabolism and pharmacokinetics of N1,N11-diethylnorspermine.
    R J Bergeron, W R Weimar, G Luchetta, R R Streiff, J Wiegand, J Perrin, K M Schreier, C Porter, G W Yao and H Dimova
    Drug Metabolism and Disposition October 1995, 23 (10) 1117-1125;
  • You have access
    Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride.
    S W Huskey, D C Dean, R R Miller, G H Rasmusson and S H Chiu
    Drug Metabolism and Disposition October 1995, 23 (10) 1126-1135;
  • You have access
    Metabolism as a determinant of species susceptibility to 2,3,5-(triglutathion-S-yl)hydroquinone-mediated nephrotoxicity. The role of N-acetylation and N-deacetylation.
    S S Lau, H E Kleiner and T J Monks
    Drug Metabolism and Disposition October 1995, 23 (10) 1136-1142;
  • You have access
    In vitro hepatic metabolism of ABT-418 in chimpanzee (Pan troglodytes). A unique pattern of microsomal flavin-containing monooxygenase-dependent stereoselective N'-oxidation.
    A D Rodrigues, M J Kukulka, J L Ferrero and J R Cashman
    Drug Metabolism and Disposition October 1995, 23 (10) 1143-1152;
  • You have access
    Identification of the human and rat P450 enzymes responsible for the sulfoxidation of S-methyl N,N-diethylthiolcarbamate (DETC-ME). The terminal step in the bioactivation of disulfiram.
    A Madan, A Parkinson and M D Faiman
    Drug Metabolism and Disposition October 1995, 23 (10) 1153-1162;
  • You have access
    Identification of the human liver cytochrome P450 enzymes involved in the metabolism of zileuton (ABT-077) and its N-dehydroxylated metabolite, Abbott-66193.
    J M Machinist, M D Mayer, M S Shet, J L Ferrero and A D Rodrigues
    Drug Metabolism and Disposition October 1995, 23 (10) 1163-1174;
  • You have access
    Determination of nicotine metabolites in rat brain after peripheral radiolabeled nicotine administration: detection of nornicotine.
    P A Crooks, M Li and L P Dwoskin
    Drug Metabolism and Disposition October 1995, 23 (10) 1175-1177;
  • You have access
    Influence of lipophilicity on the bioavailability and disposition of orally active 3-hydroxypyridin-4-one metal chelators.
    R A Yokel, A M Fredenburg, K A Meurer and T L Skinner
    Drug Metabolism and Disposition October 1995, 23 (10) 1178-1180;
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In this issue

Drug Metabolism and Disposition
Vol. 23, Issue 10
1 Oct 1995
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Most Cited
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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