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Abstract

Metabolism of mofarotene in hepatocytes and liver microsomes from different species. Comparison with in vivo data and evaluation of the cytochrome P450 isoenzymes involved in human biotransformation.

B Valles, C D Schiller, P Coassolo, G De Sousa, R Wyss, D Jaeck, A Viger-Chougnet and R Rahmani
Drug Metabolism and Disposition October 1995, 23 (10) 1051-1057;

Article Information

vol. 23 no. 10 1051-1057
PubMed 
8654192
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Published online October 1, 1995.

Author Information

  1. B Valles,
  2. C D Schiller,
  3. P Coassolo,
  4. G De Sousa,
  5. R Wyss,
  6. D Jaeck,
  7. A Viger-Chougnet and
  8. R Rahmani
  1. Pharma Division, F. Hoffmann-La Roche, Basel, Switzerland.

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    Abstract

    Metabolism of mofarotene in hepatocytes and liver microsomes from different species. Comparison with in vivo data and evaluation of the cytochrome P450 isoenzymes involved in human biotransformation.

    B Valles, C D Schiller, P Coassolo, G De Sousa, R Wyss, D Jaeck, A Viger-Chougnet and R Rahmani
    Drug Metabolism and Disposition October 1, 1995, 23 (10) 1051-1057;
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