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Abstract

In vitro hepatic metabolism of ABT-418 in chimpanzee (Pan troglodytes). A unique pattern of microsomal flavin-containing monooxygenase-dependent stereoselective N'-oxidation.

A D Rodrigues, M J Kukulka, J L Ferrero and J R Cashman
Drug Metabolism and Disposition October 1995, 23 (10) 1143-1152;

Article Information

vol. 23 no. 10 1143-1152
PubMed 
8654204
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Published online October 1, 1995.

Author Information

  1. A D Rodrigues,
  2. M J Kukulka,
  3. J L Ferrero and
  4. J R Cashman
  1. Drug Metabolism Department, Abbott Laboratories, Abbott Park, IL 60064-3500, USA.

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    Abstract

    In vitro hepatic metabolism of ABT-418 in chimpanzee (Pan troglodytes). A unique pattern of microsomal flavin-containing monooxygenase-dependent stereoselective N'-oxidation.

    A D Rodrigues, M J Kukulka, J L Ferrero and J R Cashman
    Drug Metabolism and Disposition October 1, 1995, 23 (10) 1143-1152;
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