Drug Metabolism and Disposition: 23 (11)

November 01, 1995; Volume 23,Issue 11

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The 1994 Bernard B. Brodie Award Lecture. Structure, mechanism, and inhibition of cytochrome P450.
P R Ortiz de Montellano

Drug Metabolism and Disposition November 1995, 23 (11) 1181-1187;
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Metabolites of N-ethylbenzamide, N,N-diethylbenzamide and related compounds detected in rat urine by NMR spectroscopy.
W G Taylor, T W Hall and D D Vedres

Drug Metabolism and Disposition November 1995, 23 (11) 1188-1194;
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In vitro studies to elucidate the metabolic pathway of (+)-S-145, a thromboxane A2 receptor antagonist, in rats. Evidence for two independent pathways in peroxisomal beta-oxidation.
Y Yamaguchi, T Baba, A Touchi and T Matsubara

Drug Metabolism and Disposition November 1995, 23 (11) 1195-1201;
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Dichloroacetic acid: metabolism in cytosol.
J C Lipscomb, D A Mahle, W T Brashear and H A Barton

Drug Metabolism and Disposition November 1995, 23 (11) 1202-1205;
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Pharmacokinetics and metabolic pattern after intravenous infusion and oral administration to healthy subjects.
J Schmid, U Busch, G Heinzel, G Bozler, S Kaschke and M Kummer

Drug Metabolism and Disposition November 1995, 23 (11) 1206-1213;
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Pharmacokinetics of YM175, a new bisphosphonate, in rats and dogs.
T Usui, T Watanabe and S Higuchi

Drug Metabolism and Disposition November 1995, 23 (11) 1214-1219;
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Quantitative relationship between structure and peritoneal membrane transport based on physiological pharmacokinetic concepts for acidic drugs.
E Nakashima, R Matsushita, T Ohshima, A Tsuji and F Ichimura

Drug Metabolism and Disposition November 1995, 23 (11) 1220-1224;
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Multiple forms of cytochrome P450 are involved in the metabolism of ondansetron in humans.
C M Dixon, P V Colthup, C J Serabjit-Singh, B M Kerr, C C Boehlert, G R Park and M H Tarbit

Drug Metabolism and Disposition November 1995, 23 (11) 1225-1230;
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Comparisons of phase I and phase II in vitro hepatic enzyme activities of human, dog, rhesus monkey, and cynomolgus monkey.
J E Sharer, L A Shipley, M R Vandenbranden, S N Binkley and S A Wrighton

Drug Metabolism and Disposition November 1995, 23 (11) 1231-1241;
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Metabolism and pharmacokinetics of a double prodrug of ganciclovir in the rat and monkey.
H C Krasny, L Beauchamp, T A Krenitsky and P de Miranda

Drug Metabolism and Disposition November 1995, 23 (11) 1242-1247;
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Time-dependent increase in nitric oxide formation concurrent with vasodilation induced by sodium nitroprusside, 3-morpholinosydnonimine, and S-nitroso-N-acetylpenicillamine but not by glyceryl trinitrate.
G S Marks, B E McLaughlin, S L Jimmo, M Poklewska-Koziell, J F Brien and K Nakatsu

Drug Metabolism and Disposition November 1995, 23 (11) 1248-1252;
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Oxidative metabolism of zolpidem by human liver cytochrome P450S.
L Pichard, G Gillet, C Bonfils, J Domergue, J P Thénot and P Maurel

Drug Metabolism and Disposition November 1995, 23 (11) 1253-1262;
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Major factors for the susceptibility of guinea pig to the pyrrolizidine alkaloid jacobine.
W G Chung and D R Buhler

Drug Metabolism and Disposition November 1995, 23 (11) 1263-1267;
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Purification and characterization of a dog cytochrome P450 isozyme belonging to the CYP2D subfamily and development of its antipeptide antibody.
A Nakamura, Y Yamamoto, T Tasaki, C Sugimoto, M Masuda, A Kazusaka and S Fujita

Drug Metabolism and Disposition November 1995, 23 (11) 1268-1273;
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Quantitative differences in phase I and II metabolism between rat precision-cut liver slices and isolated hepatocytes.
S Ekins, G I Murray, M D Burke, J A Williams, N C Marchant and G M Hawksworth

Drug Metabolism and Disposition November 1995, 23 (11) 1274-1279;
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Pharmacokinetics, tissue distribution, and excretion of cis-malonato[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3- dioxolane]platinum(II) in dogs.
Y B Cho, K H Kim and D K Kim

Drug Metabolism and Disposition November 1995, 23 (11) 1280-1285;
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Dexamethasone induction of taxol metabolism in the rat.
C D Anderson, J Wang, G N Kumar, J M McMillan, U K Walle and T Walle

Drug Metabolism and Disposition November 1995, 23 (11) 1286-1290;
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Induction of "male-specific" cytochrome P450 isozymes in female rats by oxandrolone.
M J Waskiewicz, S Choudhuri, S M Vanderbeck, X J Zhang and P E Thomas

Drug Metabolism and Disposition November 1995, 23 (11) 1291-1296;
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Rapid plasma clearance and metabolism in vivo of a phosphorothioate oligodeoxynucleotide with a single, internal phosphodiester bond.
R J Boado, Y S Kang, D Wu and W M Pardridge

Drug Metabolism and Disposition November 1995, 23 (11) 1297-1300;
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Debrisoquine/sparteine-type polymorphic drug metabolism in wild Clethrionomys rufocanus.
H Hoshi, M Masuda, Y Yamamoto, Y Suimamoto, A Kazusaka and S Fujita

Drug Metabolism and Disposition November 1995, 23 (11) 1301-1303;

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