Drug Metabolism and Disposition: 23 (12)

December 01, 1995; Volume 23,Issue 12

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Reduction and glucuronidation of naftazone by human and rat liver microsomes.
R Herber, B Hercelin, J Van Cantfort, J De Graeve, S Fournel-Gigleux, T Taguchi and J Magdalou

Drug Metabolism and Disposition December 1995, 23 (12) 1305-1314;
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Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability.
A Lampen, U Christians, F P Guengerich, P B Watkins, J C Kolars, A Bader, A K Gonschior, H Dralle, I Hackbarth and K F Sewing

Drug Metabolism and Disposition December 1995, 23 (12) 1315-1324;
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Microsomal metabolism of the 5-lipoxygenase inhibitors L-746,530 and L-739,010 to reactive intermediates that covalently bind to protein: the role of the 6,8-dioxabicyclo[3.2.1]octanyl moiety.
N Chauret, D Nicoll-Griffith, R Friesen, C Li, L Trimble, D Dubé, R Fortin, Y Girard and J Yergey

Drug Metabolism and Disposition December 1995, 23 (12) 1325-1334;
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Relative potency of mexiletine, lidocaine, and tocainide as inhibitors of rat liver CYP1A1 activity.
X Wei, C M Loi, E J Jarvi and R E Vestal

Drug Metabolism and Disposition December 1995, 23 (12) 1335-1338;
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Human cytochromes P4501A1 and P4501A2: R-warfarin metabolism as a probe.
Z Zhang, M J Fasco, Z Huang, F P Guengerich and L S Kaminsky

Drug Metabolism and Disposition December 1995, 23 (12) 1339-1346;
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Enzyme- and sex-specific differences in the intralobular localizations and distributions of aryl sulfotransferase IV (tyrosine-ester sulfotransferase) and alcohol (hydroxysteroid) sulfotransferase a in rat liver.
G Chen, J Baron and M W Duffel

Drug Metabolism and Disposition December 1995, 23 (12) 1346-1353;
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Slow acetylation in mice is caused by a labile and catalytically impaired mutant N-acetyltransferase (NAT2 9).
J H De Leon, K J Martell, K P Vatsis and W W Weber

Drug Metabolism and Disposition December 1995, 23 (12) 1354-1361;
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Synthesis, pharmacokinetics, and biodistribution of 67GA deferoxamineacetyl-cysteinylbiotin.
M Hashmi and S F Rosebrough

Drug Metabolism and Disposition December 1995, 23 (12) 1362-1367;
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Pharmacokinetics of sodium mercaptoundecahydrododecaborate after intravenous injection in rats.
S C Mehta, F D Boudinot and D R Lu

Drug Metabolism and Disposition December 1995, 23 (12) 1368-1371;
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Transport and metabolism of delta sleep-inducing peptide in cultured human intestinal epithelial cell monolayers.
P F Augustijns and R T Borchardt

Drug Metabolism and Disposition December 1995, 23 (12) 1372-1378;
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Enhanced rates of cytochrome P450 metabolic-intermediate complex formation from nonmacrolide amines in rifampicin-treated rabbit liver microsomes.
M R Franklin

Drug Metabolism and Disposition December 1995, 23 (12) 1379-1382;
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The pharmacokinetics of valproic acid in pregnant sheep after maternal and fetal intravenous bolus administration.
J D Gordon, K W Riggs, D W Rurak, E Kwan, C Hall and F S Abbott

Drug Metabolism and Disposition December 1995, 23 (12) 1383-1389;
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Oxidation of aldehydes catalyzed by pig liver flavin-containing monooxygenase.
G P Chen, L L Poulsen and D M Ziegler

Drug Metabolism and Disposition December 1995, 23 (12) 1390-1393;
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Pharmacokinetics of O6-benzylguanine in rats and its metabolism by rat liver microsomes.
S K Roy, E Gupta and M E Dolan

Drug Metabolism and Disposition December 1995, 23 (12) 1394-1399;
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Immunoglobulin G, F(AB')2, and fab fragment uptake kinetics in isolated perfused rat liver and rat hepatic cells.
M Bazin-Redureau, P Gires, P Chapelle, M Martinet and J M Scherrmann

Drug Metabolism and Disposition December 1995, 23 (12) 1400-1406;
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Effect of cimetidine on hepatic cytochrome P450: evidence for formation of a metabolite-intermediate complex.
M Levine and G D Bellward

Drug Metabolism and Disposition December 1995, 23 (12) 1407-1411;
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Metabolism of bromodichloroacetate in B6C3F1 mice.
G Xu, D K Stevens and R J Bull

Drug Metabolism and Disposition December 1995, 23 (12) 1412-1416;
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Biotransformation of amitriptyline by Cunninghamella elegans.
D Zhang, F E Evans, J P Freeman, B Duhart and C E Cerniglia

Drug Metabolism and Disposition December 1995, 23 (12) 1417-1425;
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Stereoselective metabolism of enflurane by human liver cytochrome P450 2E1.
K J Garton, P Yuen, J Meinwald, K E Thummel and E D Kharasch

Drug Metabolism and Disposition December 1995, 23 (12) 1426-1430;
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Selectivity of flavin-containing monooxygenase 5 for the (S)-sulfoxidation of short-chain aralkyl sulfides.
M B Fisher, M P Lawton, E Atta-Asafo-Adjei, R M Philpot and A E Rettie

Drug Metabolism and Disposition December 1995, 23 (12) 1431-1433;
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Benzyloxyresorufin as a specific substrate for the major phenobarbital-inducible dog liver cytochrome P450 (P4502B11).
P A Klekotka and J R Halpert

Drug Metabolism and Disposition December 1995, 23 (12) 1434-1435;

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