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Drug Metabolism & Disposition

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  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
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Index by author

March 01, 1995; Volume 23,Issue 3
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

B

  1. Benet, L Z

    1. You have access
      Reactivity of tolmetin glucuronide with human serum albumin. Identification of binding sites and mechanisms of reaction by tandem mass spectrometry.
      A Ding, P Zia-Amirhosseini, A F McDonagh, A L Burlingame and L Z Benet
      Drug Metabolism and Disposition March 1995, 23 (3) 369-376;
  2. Bishop, W P

    1. You have access
      Expressed human UGT1.4 protein catalyzes the formation of quaternary ammonium-linked glucuronides.
      M D Green, W P Bishop and T R Tephly
      Drug Metabolism and Disposition March 1995, 23 (3) 299-302;
  3. Blake, P

    1. You have access
      Formation of chloroethylamine and 1,3-oxazolidine-2-one following ifosfamide administration in humans.
      M S Highley, G Momerency, K Van Cauwenberghe, A T Van Oosterom, E A de Bruijn, R A Maes, P Blake, J Mansi and P G Harper
      Drug Metabolism and Disposition March 1995, 23 (3) 433-437;
  4. Bradbury, A

    1. You have access
      Kinetics of drug metabolism in rat liver slices. Rates of oxidation of ethoxycoumarin and tolbutamide, examples of high- and low-clearance compounds.
      P D Worboys, A Bradbury and J B Houston
      Drug Metabolism and Disposition March 1995, 23 (3) 393-397;
  5. Brendel, K

    1. You have access
      Sites of biotransformation for the cyclosporin derivative SDZ IMM 125 using human liver and kidney slices and intestine. Comparison with rat liver slices and cyclosporin A metabolism.
      A E Vickers, R L Fisher, K Brendel, J Guertler, R Dannecker, B Keller and V Fischer
      Drug Metabolism and Disposition March 1995, 23 (3) 327-333;
  6. Brennan, B

    1. You have access
      In vivo disposition of caffeine predicted from hepatic microsomal and hepatocyte data.
      K A Hayes, B Brennan, R Chenery and J B Houston
      Drug Metabolism and Disposition March 1995, 23 (3) 349-353;
  7. Burlingame, A L

    1. You have access
      Reactivity of tolmetin glucuronide with human serum albumin. Identification of binding sites and mechanisms of reaction by tandem mass spectrometry.
      A Ding, P Zia-Amirhosseini, A F McDonagh, A L Burlingame and L Z Benet
      Drug Metabolism and Disposition March 1995, 23 (3) 369-376;

C

  1. Chenery, R

    1. You have access
      In vivo disposition of caffeine predicted from hepatic microsomal and hepatocyte data.
      K A Hayes, B Brennan, R Chenery and J B Houston
      Drug Metabolism and Disposition March 1995, 23 (3) 349-353;
  2. Choudhury, R

    1. You have access
      Effect of iron overload on the metabolism and urinary recovery of 3-hydroxypyridin-4-one chelating agents in the rat.
      R Choudhury and S Singh
      Drug Metabolism and Disposition March 1995, 23 (3) 314-320;
  3. Creveling, C R

    1. You have access
      Induction of catechol-O-methyltransferase in the luminal epithelium of rat uterus by progesterone: inhibition by RU-486.
      K Inoue and C R Creveling
      Drug Metabolism and Disposition March 1995, 23 (3) 430-432;
  4. Cribb, A E

    1. You have access
      N4-hydroxylation of sulfamethoxazole by cytochrome P450 of the cytochrome P4502C subfamily and reduction of sulfamethoxazole hydroxylamine in human and rat hepatic microsomes.
      A E Cribb, S P Spielberg and G P Griffin
      Drug Metabolism and Disposition March 1995, 23 (3) 406-414;

D

  1. Dannecker, R

    1. You have access
      Human liver cytochrome P4503A biotransformation of the cyclosporin derivative SDZ IMM 125.
      A E Vickers, E Meyer, R Dannecker, B Keller, R E Tynes and G Maurer
      Drug Metabolism and Disposition March 1995, 23 (3) 321-326;
    2. You have access
      Sites of biotransformation for the cyclosporin derivative SDZ IMM 125 using human liver and kidney slices and intestine. Comparison with rat liver slices and cyclosporin A metabolism.
      A E Vickers, R L Fisher, K Brendel, J Guertler, R Dannecker, B Keller and V Fischer
      Drug Metabolism and Disposition March 1995, 23 (3) 327-333;
  2. de Bruijn, E A

    1. You have access
      Formation of chloroethylamine and 1,3-oxazolidine-2-one following ifosfamide administration in humans.
      M S Highley, G Momerency, K Van Cauwenberghe, A T Van Oosterom, E A de Bruijn, R A Maes, P Blake, J Mansi and P G Harper
      Drug Metabolism and Disposition March 1995, 23 (3) 433-437;
  3. De Sousa, G

    1. You have access
      Comparative metabolism of 3'-azido-3'-deoxythymidine in cultured hepatocytes from rats, dogs, monkeys, and humans.
      F Nicolas, G De Sousa, P Thomas, M Placidi, G Lorenzon and R Rahmani
      Drug Metabolism and Disposition March 1995, 23 (3) 308-313;
  4. Ding, A

    1. You have access
      Reactivity of tolmetin glucuronide with human serum albumin. Identification of binding sites and mechanisms of reaction by tandem mass spectrometry.
      A Ding, P Zia-Amirhosseini, A F McDonagh, A L Burlingame and L Z Benet
      Drug Metabolism and Disposition March 1995, 23 (3) 369-376;

E

  1. Ellis, A G

    1. You have access
      Metabolism and elimination of 5,6-dimethylxanthenone-4-acetic acid in the isolated perfused rat liver.
      L K Webster, A G Ellis, P Kestell and G W Rewcastle
      Drug Metabolism and Disposition March 1995, 23 (3) 363-368;
  2. Escousse, A

    1. You have access
      Characterization of the in vitro glucuronidation of flurbiprofen enantiomers.
      M Hamdoune, J Mounie, J Magdalou, T Masmoudi, H Goudonnet and A Escousse
      Drug Metabolism and Disposition March 1995, 23 (3) 343-348;

F

  1. Fischer, V

    1. You have access
      Sites of biotransformation for the cyclosporin derivative SDZ IMM 125 using human liver and kidney slices and intestine. Comparison with rat liver slices and cyclosporin A metabolism.
      A E Vickers, R L Fisher, K Brendel, J Guertler, R Dannecker, B Keller and V Fischer
      Drug Metabolism and Disposition March 1995, 23 (3) 327-333;
  2. Fisher, R A

    1. You have access
      Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human hepatocytes.
      T A Kocarek, E G Schuetz, S C Strom, R A Fisher and P S Guzelian
      Drug Metabolism and Disposition March 1995, 23 (3) 415-421;
  3. Fisher, R L

    1. You have access
      Sites of biotransformation for the cyclosporin derivative SDZ IMM 125 using human liver and kidney slices and intestine. Comparison with rat liver slices and cyclosporin A metabolism.
      A E Vickers, R L Fisher, K Brendel, J Guertler, R Dannecker, B Keller and V Fischer
      Drug Metabolism and Disposition March 1995, 23 (3) 327-333;

G

  1. Goudonnet, H

    1. You have access
      Characterization of the in vitro glucuronidation of flurbiprofen enantiomers.
      M Hamdoune, J Mounie, J Magdalou, T Masmoudi, H Goudonnet and A Escousse
      Drug Metabolism and Disposition March 1995, 23 (3) 343-348;
  2. Green, M D

    1. You have access
      Expressed human UGT1.4 protein catalyzes the formation of quaternary ammonium-linked glucuronides.
      M D Green, W P Bishop and T R Tephly
      Drug Metabolism and Disposition March 1995, 23 (3) 299-302;
  3. Griffin, G P

    1. You have access
      N4-hydroxylation of sulfamethoxazole by cytochrome P450 of the cytochrome P4502C subfamily and reduction of sulfamethoxazole hydroxylamine in human and rat hepatic microsomes.
      A E Cribb, S P Spielberg and G P Griffin
      Drug Metabolism and Disposition March 1995, 23 (3) 406-414;
  4. Guengerich, F P

    1. You have access
      Selectivity of cytochrome P4502E1 in chlorzoxazone 6-hydroxylation.
      H Yamazaki, Z Guo and F P Guengerich
      Drug Metabolism and Disposition March 1995, 23 (3) 438-440;
  5. Guertler, J

    1. You have access
      Sites of biotransformation for the cyclosporin derivative SDZ IMM 125 using human liver and kidney slices and intestine. Comparison with rat liver slices and cyclosporin A metabolism.
      A E Vickers, R L Fisher, K Brendel, J Guertler, R Dannecker, B Keller and V Fischer
      Drug Metabolism and Disposition March 1995, 23 (3) 327-333;
  6. Guo, Z

    1. You have access
      Selectivity of cytochrome P4502E1 in chlorzoxazone 6-hydroxylation.
      H Yamazaki, Z Guo and F P Guengerich
      Drug Metabolism and Disposition March 1995, 23 (3) 438-440;
  7. Guzelian, P S

    1. You have access
      Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human hepatocytes.
      T A Kocarek, E G Schuetz, S C Strom, R A Fisher and P S Guzelian
      Drug Metabolism and Disposition March 1995, 23 (3) 415-421;

H

  1. Hamdoune, M

    1. You have access
      Characterization of the in vitro glucuronidation of flurbiprofen enantiomers.
      M Hamdoune, J Mounie, J Magdalou, T Masmoudi, H Goudonnet and A Escousse
      Drug Metabolism and Disposition March 1995, 23 (3) 343-348;
  2. Harper, P G

    1. You have access
      Formation of chloroethylamine and 1,3-oxazolidine-2-one following ifosfamide administration in humans.
      M S Highley, G Momerency, K Van Cauwenberghe, A T Van Oosterom, E A de Bruijn, R A Maes, P Blake, J Mansi and P G Harper
      Drug Metabolism and Disposition March 1995, 23 (3) 433-437;
  3. Hayes, K A

    1. You have access
      In vivo disposition of caffeine predicted from hepatic microsomal and hepatocyte data.
      K A Hayes, B Brennan, R Chenery and J B Houston
      Drug Metabolism and Disposition March 1995, 23 (3) 349-353;
  4. Hendrickx, J

    1. You have access
      Reduction of the prodrug loperamide oxide to its active drug loperamide in the gut of rats, dogs, and humans.
      K Lavrijsen, D van Dyck, J van Houdt, J Hendrickx, J Monbaliu, R Woestenborghs, W Meuldermans and J Heykants
      Drug Metabolism and Disposition March 1995, 23 (3) 354-362;
  5. Heykants, J

    1. You have access
      Reduction of the prodrug loperamide oxide to its active drug loperamide in the gut of rats, dogs, and humans.
      K Lavrijsen, D van Dyck, J van Houdt, J Hendrickx, J Monbaliu, R Woestenborghs, W Meuldermans and J Heykants
      Drug Metabolism and Disposition March 1995, 23 (3) 354-362;
  6. Highley, M S

    1. You have access
      Formation of chloroethylamine and 1,3-oxazolidine-2-one following ifosfamide administration in humans.
      M S Highley, G Momerency, K Van Cauwenberghe, A T Van Oosterom, E A de Bruijn, R A Maes, P Blake, J Mansi and P G Harper
      Drug Metabolism and Disposition March 1995, 23 (3) 433-437;
  7. Honchel, R

    1. You have access
      Thiopurine methyltransferase pharmacogenetics. Cloning of human liver cDNA and a processed pseudogene on human chromosome 18q21.1.
      D Lee, C Szumlanski, J Houtman, R Honchel, K Rojas, J Overhauser, E D Wieben and R M Weinshilboum
      Drug Metabolism and Disposition March 1995, 23 (3) 398-405;
  8. Horton, M N

    1. You have access
      Identification of tamoxifen metabolites in human Hep G2 cell line, human liver homogenate, and patients on long-term therapy for breast cancer.
      G K Poon, B Walter, P E Lønning, M N Horton and R McCague
      Drug Metabolism and Disposition March 1995, 23 (3) 377-382;
  9. Houston, J B

    1. You have access
      In vivo disposition of caffeine predicted from hepatic microsomal and hepatocyte data.
      K A Hayes, B Brennan, R Chenery and J B Houston
      Drug Metabolism and Disposition March 1995, 23 (3) 349-353;
    2. You have access
      Kinetics of drug metabolism in rat liver slices. Rates of oxidation of ethoxycoumarin and tolbutamide, examples of high- and low-clearance compounds.
      P D Worboys, A Bradbury and J B Houston
      Drug Metabolism and Disposition March 1995, 23 (3) 393-397;
  10. Houtman, J

    1. You have access
      Thiopurine methyltransferase pharmacogenetics. Cloning of human liver cDNA and a processed pseudogene on human chromosome 18q21.1.
      D Lee, C Szumlanski, J Houtman, R Honchel, K Rojas, J Overhauser, E D Wieben and R M Weinshilboum
      Drug Metabolism and Disposition March 1995, 23 (3) 398-405;

I

  1. Inoue, K

    1. You have access
      Induction of catechol-O-methyltransferase in the luminal epithelium of rat uterus by progesterone: inhibition by RU-486.
      K Inoue and C R Creveling
      Drug Metabolism and Disposition March 1995, 23 (3) 430-432;

J

  1. Jones, A D

    1. You have access
      Biliary excretion of pyrrolic metabolites of [14C]monocrotaline in the rat.
      M W Lamé, A D Jones, D Morin, H J Segall and D W Wilson
      Drug Metabolism and Disposition March 1995, 23 (3) 422-429;

K

  1. Kaminski, D R

    1. You have access
      Sulfation and glucuronidation of acetaminophen by human hepatocytes cultured on Matrigel and type 1 collagen reproduces conjugation in vivo.
      R E Kane, A P Li and D R Kaminski
      Drug Metabolism and Disposition March 1995, 23 (3) 303-307;
  2. Kane, R E

    1. You have access
      Sulfation and glucuronidation of acetaminophen by human hepatocytes cultured on Matrigel and type 1 collagen reproduces conjugation in vivo.
      R E Kane, A P Li and D R Kaminski
      Drug Metabolism and Disposition March 1995, 23 (3) 303-307;
  3. Keller, B

    1. You have access
      Human liver cytochrome P4503A biotransformation of the cyclosporin derivative SDZ IMM 125.
      A E Vickers, E Meyer, R Dannecker, B Keller, R E Tynes and G Maurer
      Drug Metabolism and Disposition March 1995, 23 (3) 321-326;
    2. You have access
      Sites of biotransformation for the cyclosporin derivative SDZ IMM 125 using human liver and kidney slices and intestine. Comparison with rat liver slices and cyclosporin A metabolism.
      A E Vickers, R L Fisher, K Brendel, J Guertler, R Dannecker, B Keller and V Fischer
      Drug Metabolism and Disposition March 1995, 23 (3) 327-333;
  4. Kestell, P

    1. You have access
      Metabolism and elimination of 5,6-dimethylxanthenone-4-acetic acid in the isolated perfused rat liver.
      L K Webster, A G Ellis, P Kestell and G W Rewcastle
      Drug Metabolism and Disposition March 1995, 23 (3) 363-368;
  5. Kocarek, T A

    1. You have access
      Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human hepatocytes.
      T A Kocarek, E G Schuetz, S C Strom, R A Fisher and P S Guzelian
      Drug Metabolism and Disposition March 1995, 23 (3) 415-421;

L

  1. Lamé, M W

    1. You have access
      Biliary excretion of pyrrolic metabolites of [14C]monocrotaline in the rat.
      M W Lamé, A D Jones, D Morin, H J Segall and D W Wilson
      Drug Metabolism and Disposition March 1995, 23 (3) 422-429;
  2. Lavrijsen, K

    1. You have access
      Reduction of the prodrug loperamide oxide to its active drug loperamide in the gut of rats, dogs, and humans.
      K Lavrijsen, D van Dyck, J van Houdt, J Hendrickx, J Monbaliu, R Woestenborghs, W Meuldermans and J Heykants
      Drug Metabolism and Disposition March 1995, 23 (3) 354-362;
  3. Lee, D

    1. You have access
      Thiopurine methyltransferase pharmacogenetics. Cloning of human liver cDNA and a processed pseudogene on human chromosome 18q21.1.
      D Lee, C Szumlanski, J Houtman, R Honchel, K Rojas, J Overhauser, E D Wieben and R M Weinshilboum
      Drug Metabolism and Disposition March 1995, 23 (3) 398-405;
  4. Li, A P

    1. You have access
      Sulfation and glucuronidation of acetaminophen by human hepatocytes cultured on Matrigel and type 1 collagen reproduces conjugation in vivo.
      R E Kane, A P Li and D R Kaminski
      Drug Metabolism and Disposition March 1995, 23 (3) 303-307;
  5. Lønning, P E

    1. You have access
      Identification of tamoxifen metabolites in human Hep G2 cell line, human liver homogenate, and patients on long-term therapy for breast cancer.
      G K Poon, B Walter, P E Lønning, M N Horton and R McCague
      Drug Metabolism and Disposition March 1995, 23 (3) 377-382;
  6. Lorenzon, G

    1. You have access
      Comparative metabolism of 3'-azido-3'-deoxythymidine in cultured hepatocytes from rats, dogs, monkeys, and humans.
      F Nicolas, G De Sousa, P Thomas, M Placidi, G Lorenzon and R Rahmani
      Drug Metabolism and Disposition March 1995, 23 (3) 308-313;

M

  1. Maes, R A

    1. You have access
      Formation of chloroethylamine and 1,3-oxazolidine-2-one following ifosfamide administration in humans.
      M S Highley, G Momerency, K Van Cauwenberghe, A T Van Oosterom, E A de Bruijn, R A Maes, P Blake, J Mansi and P G Harper
      Drug Metabolism and Disposition March 1995, 23 (3) 433-437;
  2. Magdalou, J

    1. You have access
      Characterization of the in vitro glucuronidation of flurbiprofen enantiomers.
      M Hamdoune, J Mounie, J Magdalou, T Masmoudi, H Goudonnet and A Escousse
      Drug Metabolism and Disposition March 1995, 23 (3) 343-348;
  3. Mansi, J

    1. You have access
      Formation of chloroethylamine and 1,3-oxazolidine-2-one following ifosfamide administration in humans.
      M S Highley, G Momerency, K Van Cauwenberghe, A T Van Oosterom, E A de Bruijn, R A Maes, P Blake, J Mansi and P G Harper
      Drug Metabolism and Disposition March 1995, 23 (3) 433-437;
  4. Masmoudi, T

    1. You have access
      Characterization of the in vitro glucuronidation of flurbiprofen enantiomers.
      M Hamdoune, J Mounie, J Magdalou, T Masmoudi, H Goudonnet and A Escousse
      Drug Metabolism and Disposition March 1995, 23 (3) 343-348;
  5. Mather, L E

    1. You have access
      Comparative disposition of morphine-3-glucuronide during separate intravenous infusions of morphine and morphine-3-glucuronide in sheep. Importance of the kidney.
      R W Milne, C F McLean, L E Mather, R L Nation, W B Runciman, A J Rutten and A A Somogyi
      Drug Metabolism and Disposition March 1995, 23 (3) 334-342;
  6. Maurer, G

    1. You have access
      Human liver cytochrome P4503A biotransformation of the cyclosporin derivative SDZ IMM 125.
      A E Vickers, E Meyer, R Dannecker, B Keller, R E Tynes and G Maurer
      Drug Metabolism and Disposition March 1995, 23 (3) 321-326;
  7. McCague, R

    1. You have access
      Identification of tamoxifen metabolites in human Hep G2 cell line, human liver homogenate, and patients on long-term therapy for breast cancer.
      G K Poon, B Walter, P E Lønning, M N Horton and R McCague
      Drug Metabolism and Disposition March 1995, 23 (3) 377-382;
  8. McDonagh, A F

    1. You have access
      Reactivity of tolmetin glucuronide with human serum albumin. Identification of binding sites and mechanisms of reaction by tandem mass spectrometry.
      A Ding, P Zia-Amirhosseini, A F McDonagh, A L Burlingame and L Z Benet
      Drug Metabolism and Disposition March 1995, 23 (3) 369-376;
  9. McLean, C F

    1. You have access
      Comparative disposition of morphine-3-glucuronide during separate intravenous infusions of morphine and morphine-3-glucuronide in sheep. Importance of the kidney.
      R W Milne, C F McLean, L E Mather, R L Nation, W B Runciman, A J Rutten and A A Somogyi
      Drug Metabolism and Disposition March 1995, 23 (3) 334-342;
  10. Meuldermans, W

    1. You have access
      Reduction of the prodrug loperamide oxide to its active drug loperamide in the gut of rats, dogs, and humans.
      K Lavrijsen, D van Dyck, J van Houdt, J Hendrickx, J Monbaliu, R Woestenborghs, W Meuldermans and J Heykants
      Drug Metabolism and Disposition March 1995, 23 (3) 354-362;
  11. Meyer, E

    1. You have access
      Human liver cytochrome P4503A biotransformation of the cyclosporin derivative SDZ IMM 125.
      A E Vickers, E Meyer, R Dannecker, B Keller, R E Tynes and G Maurer
      Drug Metabolism and Disposition March 1995, 23 (3) 321-326;
  12. Milne, R W

    1. You have access
      Comparative disposition of morphine-3-glucuronide during separate intravenous infusions of morphine and morphine-3-glucuronide in sheep. Importance of the kidney.
      R W Milne, C F McLean, L E Mather, R L Nation, W B Runciman, A J Rutten and A A Somogyi
      Drug Metabolism and Disposition March 1995, 23 (3) 334-342;
  13. Mizsak, S A

    1. You have access
      In vitro metabolism of tirilazad mesylate in male and female rats. Contribution of cytochrome P4502C11 and delta 4-5 alpha-reductase.
      L C Wienkers, R C Steenwyk, S A Mizsak and P G Pearson
      Drug Metabolism and Disposition March 1995, 23 (3) 383-392;
  14. Momerency, G

    1. You have access
      Formation of chloroethylamine and 1,3-oxazolidine-2-one following ifosfamide administration in humans.
      M S Highley, G Momerency, K Van Cauwenberghe, A T Van Oosterom, E A de Bruijn, R A Maes, P Blake, J Mansi and P G Harper
      Drug Metabolism and Disposition March 1995, 23 (3) 433-437;
  15. Monbaliu, J

    1. You have access
      Reduction of the prodrug loperamide oxide to its active drug loperamide in the gut of rats, dogs, and humans.
      K Lavrijsen, D van Dyck, J van Houdt, J Hendrickx, J Monbaliu, R Woestenborghs, W Meuldermans and J Heykants
      Drug Metabolism and Disposition March 1995, 23 (3) 354-362;
  16. Morin, D

    1. You have access
      Biliary excretion of pyrrolic metabolites of [14C]monocrotaline in the rat.
      M W Lamé, A D Jones, D Morin, H J Segall and D W Wilson
      Drug Metabolism and Disposition March 1995, 23 (3) 422-429;
  17. Mounie, J

    1. You have access
      Characterization of the in vitro glucuronidation of flurbiprofen enantiomers.
      M Hamdoune, J Mounie, J Magdalou, T Masmoudi, H Goudonnet and A Escousse
      Drug Metabolism and Disposition March 1995, 23 (3) 343-348;

N

  1. Nation, R L

    1. You have access
      Comparative disposition of morphine-3-glucuronide during separate intravenous infusions of morphine and morphine-3-glucuronide in sheep. Importance of the kidney.
      R W Milne, C F McLean, L E Mather, R L Nation, W B Runciman, A J Rutten and A A Somogyi
      Drug Metabolism and Disposition March 1995, 23 (3) 334-342;
  2. Nicolas, F

    1. You have access
      Comparative metabolism of 3'-azido-3'-deoxythymidine in cultured hepatocytes from rats, dogs, monkeys, and humans.
      F Nicolas, G De Sousa, P Thomas, M Placidi, G Lorenzon and R Rahmani
      Drug Metabolism and Disposition March 1995, 23 (3) 308-313;

O

  1. Overhauser, J

    1. You have access
      Thiopurine methyltransferase pharmacogenetics. Cloning of human liver cDNA and a processed pseudogene on human chromosome 18q21.1.
      D Lee, C Szumlanski, J Houtman, R Honchel, K Rojas, J Overhauser, E D Wieben and R M Weinshilboum
      Drug Metabolism and Disposition March 1995, 23 (3) 398-405;

P

  1. Pearson, P G

    1. You have access
      In vitro metabolism of tirilazad mesylate in male and female rats. Contribution of cytochrome P4502C11 and delta 4-5 alpha-reductase.
      L C Wienkers, R C Steenwyk, S A Mizsak and P G Pearson
      Drug Metabolism and Disposition March 1995, 23 (3) 383-392;
  2. Placidi, M

    1. You have access
      Comparative metabolism of 3'-azido-3'-deoxythymidine in cultured hepatocytes from rats, dogs, monkeys, and humans.
      F Nicolas, G De Sousa, P Thomas, M Placidi, G Lorenzon and R Rahmani
      Drug Metabolism and Disposition March 1995, 23 (3) 308-313;
  3. Poon, G K

    1. You have access
      Identification of tamoxifen metabolites in human Hep G2 cell line, human liver homogenate, and patients on long-term therapy for breast cancer.
      G K Poon, B Walter, P E Lønning, M N Horton and R McCague
      Drug Metabolism and Disposition March 1995, 23 (3) 377-382;

R

  1. Rahmani, R

    1. You have access
      Comparative metabolism of 3'-azido-3'-deoxythymidine in cultured hepatocytes from rats, dogs, monkeys, and humans.
      F Nicolas, G De Sousa, P Thomas, M Placidi, G Lorenzon and R Rahmani
      Drug Metabolism and Disposition March 1995, 23 (3) 308-313;
  2. Rewcastle, G W

    1. You have access
      Metabolism and elimination of 5,6-dimethylxanthenone-4-acetic acid in the isolated perfused rat liver.
      L K Webster, A G Ellis, P Kestell and G W Rewcastle
      Drug Metabolism and Disposition March 1995, 23 (3) 363-368;
  3. Rojas, K

    1. You have access
      Thiopurine methyltransferase pharmacogenetics. Cloning of human liver cDNA and a processed pseudogene on human chromosome 18q21.1.
      D Lee, C Szumlanski, J Houtman, R Honchel, K Rojas, J Overhauser, E D Wieben and R M Weinshilboum
      Drug Metabolism and Disposition March 1995, 23 (3) 398-405;
  4. Runciman, W B

    1. You have access
      Comparative disposition of morphine-3-glucuronide during separate intravenous infusions of morphine and morphine-3-glucuronide in sheep. Importance of the kidney.
      R W Milne, C F McLean, L E Mather, R L Nation, W B Runciman, A J Rutten and A A Somogyi
      Drug Metabolism and Disposition March 1995, 23 (3) 334-342;
  5. Rutten, A J

    1. You have access
      Comparative disposition of morphine-3-glucuronide during separate intravenous infusions of morphine and morphine-3-glucuronide in sheep. Importance of the kidney.
      R W Milne, C F McLean, L E Mather, R L Nation, W B Runciman, A J Rutten and A A Somogyi
      Drug Metabolism and Disposition March 1995, 23 (3) 334-342;

S

  1. Schuetz, E G

    1. You have access
      Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human hepatocytes.
      T A Kocarek, E G Schuetz, S C Strom, R A Fisher and P S Guzelian
      Drug Metabolism and Disposition March 1995, 23 (3) 415-421;
  2. Segall, H J

    1. You have access
      Biliary excretion of pyrrolic metabolites of [14C]monocrotaline in the rat.
      M W Lamé, A D Jones, D Morin, H J Segall and D W Wilson
      Drug Metabolism and Disposition March 1995, 23 (3) 422-429;
  3. Singh, S

    1. You have access
      Effect of iron overload on the metabolism and urinary recovery of 3-hydroxypyridin-4-one chelating agents in the rat.
      R Choudhury and S Singh
      Drug Metabolism and Disposition March 1995, 23 (3) 314-320;
  4. Somogyi, A A

    1. You have access
      Comparative disposition of morphine-3-glucuronide during separate intravenous infusions of morphine and morphine-3-glucuronide in sheep. Importance of the kidney.
      R W Milne, C F McLean, L E Mather, R L Nation, W B Runciman, A J Rutten and A A Somogyi
      Drug Metabolism and Disposition March 1995, 23 (3) 334-342;
  5. Spielberg, S P

    1. You have access
      N4-hydroxylation of sulfamethoxazole by cytochrome P450 of the cytochrome P4502C subfamily and reduction of sulfamethoxazole hydroxylamine in human and rat hepatic microsomes.
      A E Cribb, S P Spielberg and G P Griffin
      Drug Metabolism and Disposition March 1995, 23 (3) 406-414;
  6. Steenwyk, R C

    1. You have access
      In vitro metabolism of tirilazad mesylate in male and female rats. Contribution of cytochrome P4502C11 and delta 4-5 alpha-reductase.
      L C Wienkers, R C Steenwyk, S A Mizsak and P G Pearson
      Drug Metabolism and Disposition March 1995, 23 (3) 383-392;
  7. Strom, S C

    1. You have access
      Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human hepatocytes.
      T A Kocarek, E G Schuetz, S C Strom, R A Fisher and P S Guzelian
      Drug Metabolism and Disposition March 1995, 23 (3) 415-421;
  8. Szumlanski, C

    1. You have access
      Thiopurine methyltransferase pharmacogenetics. Cloning of human liver cDNA and a processed pseudogene on human chromosome 18q21.1.
      D Lee, C Szumlanski, J Houtman, R Honchel, K Rojas, J Overhauser, E D Wieben and R M Weinshilboum
      Drug Metabolism and Disposition March 1995, 23 (3) 398-405;

T

  1. Tephly, T R

    1. You have access
      Expressed human UGT1.4 protein catalyzes the formation of quaternary ammonium-linked glucuronides.
      M D Green, W P Bishop and T R Tephly
      Drug Metabolism and Disposition March 1995, 23 (3) 299-302;
  2. Thomas, P

    1. You have access
      Comparative metabolism of 3'-azido-3'-deoxythymidine in cultured hepatocytes from rats, dogs, monkeys, and humans.
      F Nicolas, G De Sousa, P Thomas, M Placidi, G Lorenzon and R Rahmani
      Drug Metabolism and Disposition March 1995, 23 (3) 308-313;
  3. Tynes, R E

    1. You have access
      Human liver cytochrome P4503A biotransformation of the cyclosporin derivative SDZ IMM 125.
      A E Vickers, E Meyer, R Dannecker, B Keller, R E Tynes and G Maurer
      Drug Metabolism and Disposition March 1995, 23 (3) 321-326;

V

  1. Van Cauwenberghe, K

    1. You have access
      Formation of chloroethylamine and 1,3-oxazolidine-2-one following ifosfamide administration in humans.
      M S Highley, G Momerency, K Van Cauwenberghe, A T Van Oosterom, E A de Bruijn, R A Maes, P Blake, J Mansi and P G Harper
      Drug Metabolism and Disposition March 1995, 23 (3) 433-437;
  2. van Dyck, D

    1. You have access
      Reduction of the prodrug loperamide oxide to its active drug loperamide in the gut of rats, dogs, and humans.
      K Lavrijsen, D van Dyck, J van Houdt, J Hendrickx, J Monbaliu, R Woestenborghs, W Meuldermans and J Heykants
      Drug Metabolism and Disposition March 1995, 23 (3) 354-362;
  3. van Houdt, J

    1. You have access
      Reduction of the prodrug loperamide oxide to its active drug loperamide in the gut of rats, dogs, and humans.
      K Lavrijsen, D van Dyck, J van Houdt, J Hendrickx, J Monbaliu, R Woestenborghs, W Meuldermans and J Heykants
      Drug Metabolism and Disposition March 1995, 23 (3) 354-362;
  4. Van Oosterom, A T

    1. You have access
      Formation of chloroethylamine and 1,3-oxazolidine-2-one following ifosfamide administration in humans.
      M S Highley, G Momerency, K Van Cauwenberghe, A T Van Oosterom, E A de Bruijn, R A Maes, P Blake, J Mansi and P G Harper
      Drug Metabolism and Disposition March 1995, 23 (3) 433-437;
  5. Vickers, A E

    1. You have access
      Human liver cytochrome P4503A biotransformation of the cyclosporin derivative SDZ IMM 125.
      A E Vickers, E Meyer, R Dannecker, B Keller, R E Tynes and G Maurer
      Drug Metabolism and Disposition March 1995, 23 (3) 321-326;
    2. You have access
      Sites of biotransformation for the cyclosporin derivative SDZ IMM 125 using human liver and kidney slices and intestine. Comparison with rat liver slices and cyclosporin A metabolism.
      A E Vickers, R L Fisher, K Brendel, J Guertler, R Dannecker, B Keller and V Fischer
      Drug Metabolism and Disposition March 1995, 23 (3) 327-333;

W

  1. Walter, B

    1. You have access
      Identification of tamoxifen metabolites in human Hep G2 cell line, human liver homogenate, and patients on long-term therapy for breast cancer.
      G K Poon, B Walter, P E Lønning, M N Horton and R McCague
      Drug Metabolism and Disposition March 1995, 23 (3) 377-382;
  2. Webster, L K

    1. You have access
      Metabolism and elimination of 5,6-dimethylxanthenone-4-acetic acid in the isolated perfused rat liver.
      L K Webster, A G Ellis, P Kestell and G W Rewcastle
      Drug Metabolism and Disposition March 1995, 23 (3) 363-368;
  3. Weinshilboum, R M

    1. You have access
      Thiopurine methyltransferase pharmacogenetics. Cloning of human liver cDNA and a processed pseudogene on human chromosome 18q21.1.
      D Lee, C Szumlanski, J Houtman, R Honchel, K Rojas, J Overhauser, E D Wieben and R M Weinshilboum
      Drug Metabolism and Disposition March 1995, 23 (3) 398-405;
  4. Wieben, E D

    1. You have access
      Thiopurine methyltransferase pharmacogenetics. Cloning of human liver cDNA and a processed pseudogene on human chromosome 18q21.1.
      D Lee, C Szumlanski, J Houtman, R Honchel, K Rojas, J Overhauser, E D Wieben and R M Weinshilboum
      Drug Metabolism and Disposition March 1995, 23 (3) 398-405;
  5. Wienkers, L C

    1. You have access
      In vitro metabolism of tirilazad mesylate in male and female rats. Contribution of cytochrome P4502C11 and delta 4-5 alpha-reductase.
      L C Wienkers, R C Steenwyk, S A Mizsak and P G Pearson
      Drug Metabolism and Disposition March 1995, 23 (3) 383-392;
  6. Wilson, D W

    1. You have access
      Biliary excretion of pyrrolic metabolites of [14C]monocrotaline in the rat.
      M W Lamé, A D Jones, D Morin, H J Segall and D W Wilson
      Drug Metabolism and Disposition March 1995, 23 (3) 422-429;
  7. Woestenborghs, R

    1. You have access
      Reduction of the prodrug loperamide oxide to its active drug loperamide in the gut of rats, dogs, and humans.
      K Lavrijsen, D van Dyck, J van Houdt, J Hendrickx, J Monbaliu, R Woestenborghs, W Meuldermans and J Heykants
      Drug Metabolism and Disposition March 1995, 23 (3) 354-362;
  8. Worboys, P D

    1. You have access
      Kinetics of drug metabolism in rat liver slices. Rates of oxidation of ethoxycoumarin and tolbutamide, examples of high- and low-clearance compounds.
      P D Worboys, A Bradbury and J B Houston
      Drug Metabolism and Disposition March 1995, 23 (3) 393-397;

Y

  1. Yamazaki, H

    1. You have access
      Selectivity of cytochrome P4502E1 in chlorzoxazone 6-hydroxylation.
      H Yamazaki, Z Guo and F P Guengerich
      Drug Metabolism and Disposition March 1995, 23 (3) 438-440;

Z

  1. Zia-Amirhosseini, P

    1. You have access
      Reactivity of tolmetin glucuronide with human serum albumin. Identification of binding sites and mechanisms of reaction by tandem mass spectrometry.
      A Ding, P Zia-Amirhosseini, A F McDonagh, A L Burlingame and L Z Benet
      Drug Metabolism and Disposition March 1995, 23 (3) 369-376;
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In this issue

Drug Metabolism and Disposition
Vol. 23, Issue 3
1 Mar 1995
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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