Drug Metabolism and Disposition: 23 (5)

May 01, 1995; Volume 23,Issue 5

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Induction of nasal carboxylesterase in F344 rats following inhalation exposure to pyridine.
K J Nikula, R F Novak, I Y Chang, A R Dahl, D A Kracko, R C Zangar, S G Kim and J L Lewis

Drug Metabolism and Disposition May 1995, 23 (5) 529-535;
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The duration of induction and species influences the downregulation of cytochrome P450 by the interferon inducer polyinosinic acid-polycytidylic acid.
M R Anari, A E Cribb and K W Renton

Drug Metabolism and Disposition May 1995, 23 (5) 536-541;
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The antibiotic tiamulin is a potent inducer and inhibitor of cytochrome P4503A via the formation of a stable metabolic intermediate complex. Studies in primary hepatocyte cultures and liver microsomes of the pig.
R F Witkamp, S M Nijmeijer, M Monshouwer and A S Van Miert

Drug Metabolism and Disposition May 1995, 23 (5) 542-547;
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Identification of phenobarbital N-glucuronides as urinary metabolites of phenobarbital in mice.
S M Neighbors and W H Soine

Drug Metabolism and Disposition May 1995, 23 (5) 548-552;
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Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary culture.
M T Donato, J V Castell and M J Gómez-Lechón

Drug Metabolism and Disposition May 1995, 23 (5) 553-558;
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Acetylation and its role in the mutagenicity of the antihypertensive agent hydralazine.
L E Lemke and C A McQueen

Drug Metabolism and Disposition May 1995, 23 (5) 559-565;
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Disposition and reactivity of ibuprofen and ibufenac acyl glucuronides in vivo in the rhesus monkey and in vitro with human serum albumin.
M Castillo and P C Smith

Drug Metabolism and Disposition May 1995, 23 (5) 566-572;
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An improved pharmacodynamic model for formation of methemoglobin by antimalarial drugs.
A A Fasanmade and W J Jusko

Drug Metabolism and Disposition May 1995, 23 (5) 573-576;
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Selectivity and kinetics of inactivation of rabbit hepatic cytochromes P450 2B4 and 2B5 by N-aralkylated derivatives of 1-aminobenzotriazole.
S W Grimm, J R Bend and J R Halpert

Drug Metabolism and Disposition May 1995, 23 (5) 577-583;
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Presystemic elimination of morphine in anesthetized rabbits. Contribution of the intestine, liver, and lungs.
C Abdallah, J G Besner and P Du Souich

Drug Metabolism and Disposition May 1995, 23 (5) 584-589;
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Covalent binding of carbamazepine oxidative metabolites to neutrophils.
S M Furst, P Sukhai, R A McClelland and J P Uetrecht

Drug Metabolism and Disposition May 1995, 23 (5) 590-594;
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Oxidation at C-1 controls the cytotoxicity of 1,1-dichloro-2,2- bis(p-chlorophenyl)ethane by rabbit and human lung cells.
W K Nichols, C M Terry, N S Cutler, M L Appleton, P K Jesthi and G S Yost

Drug Metabolism and Disposition May 1995, 23 (5) 595-599;
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Identification of two regioisomeric monocarboxylic acid metabolites of losoxantrone (DuP 941; Biantrazole) excreted in human urine.
L E Richards and J H Sun

Drug Metabolism and Disposition May 1995, 23 (5) 600-602;
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Pharmacokinetics and presystemic hepatic first-pass elimination of a novel sigma receptor antagonist, DuP 734, in the rat.
R P Kapil and G N Lam

Drug Metabolism and Disposition May 1995, 23 (5) 603-606;

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