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Drug Metabolism & Disposition

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Index by author

May 01, 1995; Volume 23,Issue 5
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Abdallah, C

    1. You have access
      Presystemic elimination of morphine in anesthetized rabbits. Contribution of the intestine, liver, and lungs.
      C Abdallah, J G Besner and P Du Souich
      Drug Metabolism and Disposition May 1995, 23 (5) 584-589;
  2. Anari, M R

    1. You have access
      The duration of induction and species influences the downregulation of cytochrome P450 by the interferon inducer polyinosinic acid-polycytidylic acid.
      M R Anari, A E Cribb and K W Renton
      Drug Metabolism and Disposition May 1995, 23 (5) 536-541;
  3. Appleton, M L

    1. You have access
      Oxidation at C-1 controls the cytotoxicity of 1,1-dichloro-2,2- bis(p-chlorophenyl)ethane by rabbit and human lung cells.
      W K Nichols, C M Terry, N S Cutler, M L Appleton, P K Jesthi and G S Yost
      Drug Metabolism and Disposition May 1995, 23 (5) 595-599;

B

  1. Bend, J R

    1. You have access
      Selectivity and kinetics of inactivation of rabbit hepatic cytochromes P450 2B4 and 2B5 by N-aralkylated derivatives of 1-aminobenzotriazole.
      S W Grimm, J R Bend and J R Halpert
      Drug Metabolism and Disposition May 1995, 23 (5) 577-583;
  2. Besner, J G

    1. You have access
      Presystemic elimination of morphine in anesthetized rabbits. Contribution of the intestine, liver, and lungs.
      C Abdallah, J G Besner and P Du Souich
      Drug Metabolism and Disposition May 1995, 23 (5) 584-589;

C

  1. Castell, J V

    1. You have access
      Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary culture.
      M T Donato, J V Castell and M J Gómez-Lechón
      Drug Metabolism and Disposition May 1995, 23 (5) 553-558;
  2. Castillo, M

    1. You have access
      Disposition and reactivity of ibuprofen and ibufenac acyl glucuronides in vivo in the rhesus monkey and in vitro with human serum albumin.
      M Castillo and P C Smith
      Drug Metabolism and Disposition May 1995, 23 (5) 566-572;
  3. Chang, I Y

    1. You have access
      Induction of nasal carboxylesterase in F344 rats following inhalation exposure to pyridine.
      K J Nikula, R F Novak, I Y Chang, A R Dahl, D A Kracko, R C Zangar, S G Kim and J L Lewis
      Drug Metabolism and Disposition May 1995, 23 (5) 529-535;
  4. Cribb, A E

    1. You have access
      The duration of induction and species influences the downregulation of cytochrome P450 by the interferon inducer polyinosinic acid-polycytidylic acid.
      M R Anari, A E Cribb and K W Renton
      Drug Metabolism and Disposition May 1995, 23 (5) 536-541;
  5. Cutler, N S

    1. You have access
      Oxidation at C-1 controls the cytotoxicity of 1,1-dichloro-2,2- bis(p-chlorophenyl)ethane by rabbit and human lung cells.
      W K Nichols, C M Terry, N S Cutler, M L Appleton, P K Jesthi and G S Yost
      Drug Metabolism and Disposition May 1995, 23 (5) 595-599;

D

  1. Dahl, A R

    1. You have access
      Induction of nasal carboxylesterase in F344 rats following inhalation exposure to pyridine.
      K J Nikula, R F Novak, I Y Chang, A R Dahl, D A Kracko, R C Zangar, S G Kim and J L Lewis
      Drug Metabolism and Disposition May 1995, 23 (5) 529-535;
  2. Donato, M T

    1. You have access
      Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary culture.
      M T Donato, J V Castell and M J Gómez-Lechón
      Drug Metabolism and Disposition May 1995, 23 (5) 553-558;
  3. Du Souich, P

    1. You have access
      Presystemic elimination of morphine in anesthetized rabbits. Contribution of the intestine, liver, and lungs.
      C Abdallah, J G Besner and P Du Souich
      Drug Metabolism and Disposition May 1995, 23 (5) 584-589;

F

  1. Fasanmade, A A

    1. You have access
      An improved pharmacodynamic model for formation of methemoglobin by antimalarial drugs.
      A A Fasanmade and W J Jusko
      Drug Metabolism and Disposition May 1995, 23 (5) 573-576;
  2. Furst, S M

    1. You have access
      Covalent binding of carbamazepine oxidative metabolites to neutrophils.
      S M Furst, P Sukhai, R A McClelland and J P Uetrecht
      Drug Metabolism and Disposition May 1995, 23 (5) 590-594;

G

  1. Gómez-Lechón, M J

    1. You have access
      Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary culture.
      M T Donato, J V Castell and M J Gómez-Lechón
      Drug Metabolism and Disposition May 1995, 23 (5) 553-558;
  2. Grimm, S W

    1. You have access
      Selectivity and kinetics of inactivation of rabbit hepatic cytochromes P450 2B4 and 2B5 by N-aralkylated derivatives of 1-aminobenzotriazole.
      S W Grimm, J R Bend and J R Halpert
      Drug Metabolism and Disposition May 1995, 23 (5) 577-583;

H

  1. Halpert, J R

    1. You have access
      Selectivity and kinetics of inactivation of rabbit hepatic cytochromes P450 2B4 and 2B5 by N-aralkylated derivatives of 1-aminobenzotriazole.
      S W Grimm, J R Bend and J R Halpert
      Drug Metabolism and Disposition May 1995, 23 (5) 577-583;

J

  1. Jesthi, P K

    1. You have access
      Oxidation at C-1 controls the cytotoxicity of 1,1-dichloro-2,2- bis(p-chlorophenyl)ethane by rabbit and human lung cells.
      W K Nichols, C M Terry, N S Cutler, M L Appleton, P K Jesthi and G S Yost
      Drug Metabolism and Disposition May 1995, 23 (5) 595-599;
  2. Jusko, W J

    1. You have access
      An improved pharmacodynamic model for formation of methemoglobin by antimalarial drugs.
      A A Fasanmade and W J Jusko
      Drug Metabolism and Disposition May 1995, 23 (5) 573-576;

K

  1. Kapil, R P

    1. You have access
      Pharmacokinetics and presystemic hepatic first-pass elimination of a novel sigma receptor antagonist, DuP 734, in the rat.
      R P Kapil and G N Lam
      Drug Metabolism and Disposition May 1995, 23 (5) 603-606;
  2. Kim, S G

    1. You have access
      Induction of nasal carboxylesterase in F344 rats following inhalation exposure to pyridine.
      K J Nikula, R F Novak, I Y Chang, A R Dahl, D A Kracko, R C Zangar, S G Kim and J L Lewis
      Drug Metabolism and Disposition May 1995, 23 (5) 529-535;
  3. Kracko, D A

    1. You have access
      Induction of nasal carboxylesterase in F344 rats following inhalation exposure to pyridine.
      K J Nikula, R F Novak, I Y Chang, A R Dahl, D A Kracko, R C Zangar, S G Kim and J L Lewis
      Drug Metabolism and Disposition May 1995, 23 (5) 529-535;

L

  1. Lam, G N

    1. You have access
      Pharmacokinetics and presystemic hepatic first-pass elimination of a novel sigma receptor antagonist, DuP 734, in the rat.
      R P Kapil and G N Lam
      Drug Metabolism and Disposition May 1995, 23 (5) 603-606;
  2. Lemke, L E

    1. You have access
      Acetylation and its role in the mutagenicity of the antihypertensive agent hydralazine.
      L E Lemke and C A McQueen
      Drug Metabolism and Disposition May 1995, 23 (5) 559-565;
  3. Lewis, J L

    1. You have access
      Induction of nasal carboxylesterase in F344 rats following inhalation exposure to pyridine.
      K J Nikula, R F Novak, I Y Chang, A R Dahl, D A Kracko, R C Zangar, S G Kim and J L Lewis
      Drug Metabolism and Disposition May 1995, 23 (5) 529-535;

M

  1. McClelland, R A

    1. You have access
      Covalent binding of carbamazepine oxidative metabolites to neutrophils.
      S M Furst, P Sukhai, R A McClelland and J P Uetrecht
      Drug Metabolism and Disposition May 1995, 23 (5) 590-594;
  2. McQueen, C A

    1. You have access
      Acetylation and its role in the mutagenicity of the antihypertensive agent hydralazine.
      L E Lemke and C A McQueen
      Drug Metabolism and Disposition May 1995, 23 (5) 559-565;
  3. Monshouwer, M

    1. You have access
      The antibiotic tiamulin is a potent inducer and inhibitor of cytochrome P4503A via the formation of a stable metabolic intermediate complex. Studies in primary hepatocyte cultures and liver microsomes of the pig.
      R F Witkamp, S M Nijmeijer, M Monshouwer and A S Van Miert
      Drug Metabolism and Disposition May 1995, 23 (5) 542-547;

N

  1. Neighbors, S M

    1. You have access
      Identification of phenobarbital N-glucuronides as urinary metabolites of phenobarbital in mice.
      S M Neighbors and W H Soine
      Drug Metabolism and Disposition May 1995, 23 (5) 548-552;
  2. Nichols, W K

    1. You have access
      Oxidation at C-1 controls the cytotoxicity of 1,1-dichloro-2,2- bis(p-chlorophenyl)ethane by rabbit and human lung cells.
      W K Nichols, C M Terry, N S Cutler, M L Appleton, P K Jesthi and G S Yost
      Drug Metabolism and Disposition May 1995, 23 (5) 595-599;
  3. Nijmeijer, S M

    1. You have access
      The antibiotic tiamulin is a potent inducer and inhibitor of cytochrome P4503A via the formation of a stable metabolic intermediate complex. Studies in primary hepatocyte cultures and liver microsomes of the pig.
      R F Witkamp, S M Nijmeijer, M Monshouwer and A S Van Miert
      Drug Metabolism and Disposition May 1995, 23 (5) 542-547;
  4. Nikula, K J

    1. You have access
      Induction of nasal carboxylesterase in F344 rats following inhalation exposure to pyridine.
      K J Nikula, R F Novak, I Y Chang, A R Dahl, D A Kracko, R C Zangar, S G Kim and J L Lewis
      Drug Metabolism and Disposition May 1995, 23 (5) 529-535;
  5. Novak, R F

    1. You have access
      Induction of nasal carboxylesterase in F344 rats following inhalation exposure to pyridine.
      K J Nikula, R F Novak, I Y Chang, A R Dahl, D A Kracko, R C Zangar, S G Kim and J L Lewis
      Drug Metabolism and Disposition May 1995, 23 (5) 529-535;

R

  1. Renton, K W

    1. You have access
      The duration of induction and species influences the downregulation of cytochrome P450 by the interferon inducer polyinosinic acid-polycytidylic acid.
      M R Anari, A E Cribb and K W Renton
      Drug Metabolism and Disposition May 1995, 23 (5) 536-541;
  2. Richards, L E

    1. You have access
      Identification of two regioisomeric monocarboxylic acid metabolites of losoxantrone (DuP 941; Biantrazole) excreted in human urine.
      L E Richards and J H Sun
      Drug Metabolism and Disposition May 1995, 23 (5) 600-602;

S

  1. Smith, P C

    1. You have access
      Disposition and reactivity of ibuprofen and ibufenac acyl glucuronides in vivo in the rhesus monkey and in vitro with human serum albumin.
      M Castillo and P C Smith
      Drug Metabolism and Disposition May 1995, 23 (5) 566-572;
  2. Soine, W H

    1. You have access
      Identification of phenobarbital N-glucuronides as urinary metabolites of phenobarbital in mice.
      S M Neighbors and W H Soine
      Drug Metabolism and Disposition May 1995, 23 (5) 548-552;
  3. Sukhai, P

    1. You have access
      Covalent binding of carbamazepine oxidative metabolites to neutrophils.
      S M Furst, P Sukhai, R A McClelland and J P Uetrecht
      Drug Metabolism and Disposition May 1995, 23 (5) 590-594;
  4. Sun, J H

    1. You have access
      Identification of two regioisomeric monocarboxylic acid metabolites of losoxantrone (DuP 941; Biantrazole) excreted in human urine.
      L E Richards and J H Sun
      Drug Metabolism and Disposition May 1995, 23 (5) 600-602;

T

  1. Terry, C M

    1. You have access
      Oxidation at C-1 controls the cytotoxicity of 1,1-dichloro-2,2- bis(p-chlorophenyl)ethane by rabbit and human lung cells.
      W K Nichols, C M Terry, N S Cutler, M L Appleton, P K Jesthi and G S Yost
      Drug Metabolism and Disposition May 1995, 23 (5) 595-599;

U

  1. Uetrecht, J P

    1. You have access
      Covalent binding of carbamazepine oxidative metabolites to neutrophils.
      S M Furst, P Sukhai, R A McClelland and J P Uetrecht
      Drug Metabolism and Disposition May 1995, 23 (5) 590-594;

V

  1. Van Miert, A S

    1. You have access
      The antibiotic tiamulin is a potent inducer and inhibitor of cytochrome P4503A via the formation of a stable metabolic intermediate complex. Studies in primary hepatocyte cultures and liver microsomes of the pig.
      R F Witkamp, S M Nijmeijer, M Monshouwer and A S Van Miert
      Drug Metabolism and Disposition May 1995, 23 (5) 542-547;

W

  1. Witkamp, R F

    1. You have access
      The antibiotic tiamulin is a potent inducer and inhibitor of cytochrome P4503A via the formation of a stable metabolic intermediate complex. Studies in primary hepatocyte cultures and liver microsomes of the pig.
      R F Witkamp, S M Nijmeijer, M Monshouwer and A S Van Miert
      Drug Metabolism and Disposition May 1995, 23 (5) 542-547;

Y

  1. Yost, G S

    1. You have access
      Oxidation at C-1 controls the cytotoxicity of 1,1-dichloro-2,2- bis(p-chlorophenyl)ethane by rabbit and human lung cells.
      W K Nichols, C M Terry, N S Cutler, M L Appleton, P K Jesthi and G S Yost
      Drug Metabolism and Disposition May 1995, 23 (5) 595-599;

Z

  1. Zangar, R C

    1. You have access
      Induction of nasal carboxylesterase in F344 rats following inhalation exposure to pyridine.
      K J Nikula, R F Novak, I Y Chang, A R Dahl, D A Kracko, R C Zangar, S G Kim and J L Lewis
      Drug Metabolism and Disposition May 1995, 23 (5) 529-535;
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In this issue

Drug Metabolism and Disposition
Vol. 23, Issue 5
1 May 1995
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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