Abstract
The antibiotic tiamulin is a potent inducer and inhibitor of cytochrome P4503A via the formation of a stable metabolic intermediate complex. Studies in primary hepatocyte cultures and liver microsomes of the pig.
R F Witkamp, S M Nijmeijer, M Monshouwer and A S Van Miert
Drug Metabolism and Disposition May 1995, 23 (5) 542-547;