Drug Metabolism and Disposition: 24 (12)

December 01, 1996; Volume 24,Issue 12

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Identification of 6',7'-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice.
D J Edwards, F H Bellevue and P M Woster

Drug Metabolism and Disposition December 1996, 24 (12) 1287-1290;
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Retention mechanism of imidazoles in connective tissue. I. Binding to elastin.
K Ohta, J I Yamaguchi, M Akimoto, K Fukushima, T Suwa and S Awazu

Drug Metabolism and Disposition December 1996, 24 (12) 1291-1297;
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Sex-dependent pharmacokinetics of indinavir: in vivo and in vitro evidence.
J H Lin, M Chiba, I W Chen, J A Nishime and K J Vastag

Drug Metabolism and Disposition December 1996, 24 (12) 1298-1306;
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Characterization of the NADPH-dependent covalent binding of [14C]halothane to human liver microsomes: a role for cytochrome P4502E1 at low substrate concentrations.
A Madan and A Parkinson

Drug Metabolism and Disposition December 1996, 24 (12) 1307-1313;
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Stable expression and coexpression of human cytochrome P450 oxidoreductase and cytochrome P450 1A2 in V79 Chinese hamster cells: sensitivity to quinones and biotransformation of 7-alkoxyresorufins and triazines.
W A Schmalix, D Lang, A Schneider, R Bocker, H Greim and J Doehmer

Drug Metabolism and Disposition December 1996, 24 (12) 1314-1319;
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Structural characteristics of flavin-containing monooxygenase genes one and two (FMO1 and FMO2).
M K Wyatt, R M Philpot, G Carver, M P Lawton and K N Nikbakht

Drug Metabolism and Disposition December 1996, 24 (12) 1320-1327;
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Human jejunal estrogen sulfotransferase and dehydroepiandrosterone sulfotransferase: immunochemical characterization of individual variation.
C Her, C Szumlanski, I A Aksoy and R M Weinshilboum

Drug Metabolism and Disposition December 1996, 24 (12) 1328-1335;
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Inhibition of (mono)amine oxidase activity and prevention of ifosfamide encephalopathy by methylene blue.
C Aeschlimann, T Cerny and A Küpfer

Drug Metabolism and Disposition December 1996, 24 (12) 1336-1339;
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Pharmacokinetic analysis of chloral hydrate and its metabolism in B6C3F1 mice.
R R Abbas, C S Seckel, J K Kidney and J W Fisher

Drug Metabolism and Disposition December 1996, 24 (12) 1340-1346;
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Does hepatic ATP depletion impair glycine conjugation in vivo?
Z Gregus, T Fekete, E Halászi and C D Klaassen

Drug Metabolism and Disposition December 1996, 24 (12) 1347-1354;
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Pharmacokinetics of the chemoprophylactic and chemotherapeutic trypanocidal drug isometamidium chloride (Samorin) in cattle.
M C Eisler

Drug Metabolism and Disposition December 1996, 24 (12) 1355-1361;
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Catalysis of the dealkylation/debenzylation of phenoxazone ethers by hemoglobin in the absence of peroxides: implications for investigations of embryonic biotransformation.
M R Juchau, D E Chapman, H Y Yang, Q P Lee, M J Namkung and T R Hinds

Drug Metabolism and Disposition December 1996, 24 (12) 1362-1368;
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Orally active inhibitors of human leukocyte elastase. I. Disposition of L-683,845 in rats and rhesus monkeys.
S H Vincent, S K Painter, P A Krieter, A E Colletti, E Lyszack, A Rosegay, D Dean, D Luffer-Atlas, R R Miller, C Cioffe and S H Chiu

Drug Metabolism and Disposition December 1996, 24 (12) 1369-1377;
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Conjugation of para-nitrophenol by isolated perfused fetal sheep liver.
J A Ring, H Ghabrial, M S Ching, A Shulkes, R A Smallwood and D J Morgan

Drug Metabolism and Disposition December 1996, 24 (12) 1378-1384;
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Meeting report: receptor-acting xenobiotics and their risk assessment.
A D Poland

Drug Metabolism and Disposition December 1996, 24 (12) 1385-1388;
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Disposition of indinavir, a potent HIV-1 protease inhibitor, after an oral dose in humans.
S K Balani, E J Woolf, V L Hoagland, M G Sturgill, P J Deutsch, K C Yeh and J H Lin

Drug Metabolism and Disposition December 1996, 24 (12) 1389-1394;
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Characterization of intermediates in the oxidation of zinc fingers in human immunodeficiency virus type 1 nucleocapsid protein P7.
Y Hathout, D Fabris, M S Han, R C Sowder, L E Henderson and C Fenselau

Drug Metabolism and Disposition December 1996, 24 (12) 1395-1400;
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Roles of cytochrome P4502C9 and cytochrome P4502C19 in the stereoselective metabolism of phenytoin to its major metabolite.
M Bajpai, L K Roskos, D D Shen and R H Levy

Drug Metabolism and Disposition December 1996, 24 (12) 1401-1403;

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