Drug Metabolism and Disposition: 24 (2)

February 01, 1996; Volume 24,Issue 2

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Kinetics of acetyl coenzyme A:arylamine N-acetyltransferase from rapid and slow acetylator frog tissues.
C C Ho, T H Lin, Y S Lai, J G Chung, G N Levy and W W Weber

Drug Metabolism and Disposition February 1996, 24 (2) 137-141;
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Inhibition of the intestinal digoxin absorption and exsorption by quinidine.
S F Su and J D Huang

Drug Metabolism and Disposition February 1996, 24 (2) 142-147;
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Tissue distribution and pharmacokinetics of centchroman. A new nonsteroidal postcoital contraceptive agent and its 7-desmethyl metabolite in female rats after a single oral dose.
J K Paliwal and R C Gupta

Drug Metabolism and Disposition February 1996, 24 (2) 148-155;
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Absorption, distribution, metabolism, and excretion of N,N-diethyl-M-toluamide in the rat.
G P Schoenig, R E Hartnagel, T G Osimitz and S Llanso

Drug Metabolism and Disposition February 1996, 24 (2) 156-163;
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Metabolic interactions of putative cytochrome P4503A substrates with alternative pathways of dapsone metabolism in human liver microsomes.
Y Irshaid, R A Branch and A Adedoyin

Drug Metabolism and Disposition February 1996, 24 (2) 164-171;
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Pharmacokinetics and metabolism of EXP921, a novel cognitive enhancer, in rats.
Y N Wong, C Y Quon, K A Holm, D L Burcham, N L Frey, S M Huang and G N Lam

Drug Metabolism and Disposition February 1996, 24 (2) 172-179;
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Hydroxylation of lauramide diethanolamine by liver microsomes.
J Merdink, K Decosta, J M Mathews, C B Jones, J R Okita and R T Okita

Drug Metabolism and Disposition February 1996, 24 (2) 180-186;
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In vitro and in vivo biotransformation of 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-D]pyrimidine (U-89843) in the rat.
Z Zhao, K A Koeplinger, G L Bundy, L S Banitt, G E Padbury, M J Hauer and P E Sanders

Drug Metabolism and Disposition February 1996, 24 (2) 187-198;
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Involvement of mammalian liver cytosols and aldehyde oxidase in reductive metabolism of zonisamide.
K Sugihara, S Kitamura and K Tatsumi

Drug Metabolism and Disposition February 1996, 24 (2) 199-202;
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Modeling the cytochrome P450-mediated metabolism of chlorinated volatile organic compounds.
C L Waller, M V Evans and J D McKinney

Drug Metabolism and Disposition February 1996, 24 (2) 203-210;
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Comparison of ketoconazole and fluconazole as cytochrome P450 inhibitors. Use of steady-state infusion approach to achieve plasma concentration-response relationships.
C M Ervine, D E Matthew, B Brennan and J B Houston

Drug Metabolism and Disposition February 1996, 24 (2) 211-215;
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Local absorption kinetics into the portal system using the portal-venous concentration difference after an oral dose of diclofenac in the awakening rat. Accelerative effect of bile on intestinal absorption of diclofenac.
K Tabata, K Yamaoka, T Fukuyama and T Nakagawa

Drug Metabolism and Disposition February 1996, 24 (2) 216-220;
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Biotransformation of lifibrol (U-83860) to mixed glyceride metabolites by rat and human hepatocytes in primary culture.
E L Sun, K L Feenstra, F P Bell, P E Sanders, J G Slatter and R G Ulrich

Drug Metabolism and Disposition February 1996, 24 (2) 221-231;
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Flavonoids, potent inhibitors of the human P-form phenolsulfotransferase. Potential role in drug metabolism and chemoprevention.
E A Eaton, U K Walle, A J Lewis, T Hudson, A A Wilson and T Walle

Drug Metabolism and Disposition February 1996, 24 (2) 232-237;
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3,3',4,4'-tetrachloroazobenzene absorption, disposition, and metabolism in male Fischer 344 rats.
U A Pillai, T L Ziegler, D X Wang, M J Kattnig, T McClure, D C Liebler, M Mayersohn and I G Sipes

Drug Metabolism and Disposition February 1996, 24 (2) 238-244;
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Arylamine N-acetyltransferases. Expression in Escherichia coli, purification, and substrate specificities of recombinant hamster monomorphic and polymorphic isozymes.
C R Wagner, C P Bergstrom, K R Koning and P E Hanna

Drug Metabolism and Disposition February 1996, 24 (2) 245-253;
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Effect of 3-methylcholanthrene on bunitrolol metabolism. Kinetics and immunological studies on 4-hydroxylation of bunitrolol catalyzed by two species of cytochromes P450 in rat liver microsomes.
S Fujita, M Masuda, Y Shimamoto, H Hoshi, S Kariya, A Kazusaka and T Suzuki

Drug Metabolism and Disposition February 1996, 24 (2) 254-259;
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Putative active site template model for cytochrome P4502C9 (tolbutamide hydroxylase).
B C Jones, G Hawksworth, V A Horne, A Newlands, J Morsman, M S Tute and D A Smith

Drug Metabolism and Disposition February 1996, 24 (2) 260-266;
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Pharmacokinetics and biodistribution of 131I-labeled trigalactose conjugate of streptavidin.
M Hashmi and S F Rosebrough

Drug Metabolism and Disposition February 1996, 24 (2) 267-269;
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Influence of probenecid on the renal excretion mechanisms of cefadroxil.
M J Gimeno, M Martínez, L Granero, F Torres-Molina and J E Peris

Drug Metabolism and Disposition February 1996, 24 (2) 270-272;

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