Drug Metabolism and Disposition: 24 (9)

September 01, 1996; Volume 24,Issue 9

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Dietary indole-3-carbinol inhibits FMO activity and the expression of flavin-containing monooxygenase form 1 in rat liver and intestine.
S Larsen-Su and D E Williams

Drug Metabolism and Disposition September 1996, 24 (9) 927-931;
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Metabolism of fentanyl, a synthetic opioid analgesic, by human liver microsomes. Role of CYP3A4.
D E Feierman and J M Lasker

Drug Metabolism and Disposition September 1996, 24 (9) 932-939;
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Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450.
A Ghosal, H Satoh, P E Thomas, E Bush and D Moore

Drug Metabolism and Disposition September 1996, 24 (9) 940-947;
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Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin.
H Heyn, R B White and J C Stevens

Drug Metabolism and Disposition September 1996, 24 (9) 948-954;
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Ropivacaine, a new amide-type local anesthetic agent, is metabolized by cytochromes P450 1A and 3A in human liver microsomes.
G Ekström and U B Gunnarsson

Drug Metabolism and Disposition September 1996, 24 (9) 955-961;
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Metabolism and excretion of ropivacaine in humans.
M M Halldin, E Bredberg, B Angelin, T Arvidsson, Y Askemark, S Elofsson and M Widman

Drug Metabolism and Disposition September 1996, 24 (9) 962-968;
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Comparative metabolism of the nonsteroidal antiinflammatory drug, aceclofenac, in the rat, monkey, and human.
R Bort, X Ponsoda, E Carrasco, M J Gómez-Lechón and J V Castell

Drug Metabolism and Disposition September 1996, 24 (9) 969-975;
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Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4.
D K Spracklin, K E Thummel and E D Kharasch

Drug Metabolism and Disposition September 1996, 24 (9) 976-983;
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Disposition of gemfibrozil and gemfibrozil acyl glucuronide in the rat isolated perfused liver.
B C Sallustio, B A Fairchild, K Shanahan, A M Evans and R L Nation

Drug Metabolism and Disposition September 1996, 24 (9) 984-989;
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Xenobiotic metabolism in rat, dog, and human precision-cut liver slices, freshly isolated hepatocytes, and vitrified precision-cut liver slices.
S Ekins, J A Williams, G I Murray, M D Burke, N C Marchant, J Engeset and G M Hawksworth

Drug Metabolism and Disposition September 1996, 24 (9) 990-995;
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Kinetics and selectivity of mechanism-based inhibition of guinea pig hepatic and pulmonary cytochrome P450 by N-benzyl-1-aminobenzotriazole and N-alpha-methylbenzyl-1-aminobenzotriazole.
C J Sinal and J R Bend

Drug Metabolism and Disposition September 1996, 24 (9) 996-1001;
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Stereoselective metabolism of a new anticonvulsant drug candidate, losigamone, by human liver microsomes.
C D Torchin, P J McNeilly, I M Kapetanovic, J M Strong and H J Kupferberg

Drug Metabolism and Disposition September 1996, 24 (9) 1002-1008;
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Absorption and disposition kinetics of 3,3',4,4'-tetrachloroazoxybenzene in the male Fischer 344 rat.
T L Ziegler, U A Pillai, R L Smith, M J Kattnig, D C Liebler, M Mayersohn and I G Sipes

Drug Metabolism and Disposition September 1996, 24 (9) 1009-1014;
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Busulfan conjugation by glutathione S-transferases alpha, mu, and pi.
M Czerwinski, J P Gibbs and J T Slattery

Drug Metabolism and Disposition September 1996, 24 (9) 1015-1019;
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Covalent binding to DNA in vitro of 2',3'-oxides derived from allylbenzene analogs.
G Luo and T M Guenthner

Drug Metabolism and Disposition September 1996, 24 (9) 1020-1027;
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Hemodynamic effects of N-acetylamrinone in a porcine model of group B streptococcal sepsis.
E M Allen, M Rowin, J B Pappas, D D Vernon and J M Dean

Drug Metabolism and Disposition September 1996, 24 (9) 1028-1031;
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Disposition of metabolically radiolabeled CE9.1--a macaque-human chimeric anti-human CD4 monoclonal antibody--in transgenic mice bearing human CD4.
C B Davis, E M Garver, D C Kwok and J J Urbanski

Drug Metabolism and Disposition September 1996, 24 (9) 1032-1037;
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Substrate probe for the mechanism of aromatic hydroxylation catalyzed by cytochrome P450.
J F Darbyshire, K R Iyer, J Grogan, K R Korzekwa and W F Trager

Drug Metabolism and Disposition September 1996, 24 (9) 1038-1045;

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