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Drug Metabolism & Disposition

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Table of Contents

November 01, 1997; Volume 25,Issue 11

Accelerated Communications

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    Glutathione-Dependent Conversion to Glyoxylate, a Major Pathway of Dichloroacetate Biotransformation in Hepatic Cytosol from Humans and Rats, is Reduced in Dichloroacetate-Treated Rats
    M. O. James, R. Cornett, Z. Yan, G. N. Henderson and P. W. Stacpoole
    Drug Metabolism and Disposition November 1997, 25 (11) 1223-1227;
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    Mechanisms of Enhanced Oral Availability of CYP3A4 Substrates by Grapefruit Constituents
    Phyllissa Schmiedlin-Ren, David J. Edwards, Michael E. Fitzsimmons, Kan He, Kenneth S. Lown, Patrick M. Woster, Atiqur Rahman, Kenneth E. Thummel, Jeannine M. Fisher, Paul F. Hollenberg and Paul B. Watkins
    Drug Metabolism and Disposition November 1997, 25 (11) 1228-1233;

Articles

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    Heterologous Expression of Human Drug-metabolizing Enzymes
    F. Peter Guengerich, Asit Parikh, Eric F. Johnson, Toby H. Richardson, Claes von Wachenfeldt, Jose Cosme, Frank Jung, Christian P. Strassburg, Michael P. Manns, Robert H. Tukey, Mike Pritchard, Sylvie Fournel-Gigleux and Brian Burchell
    Drug Metabolism and Disposition November 1997, 25 (11) 1234-1241;
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    Inactivation of Cytochrome P450s 2B1, 2B4, 2B6, and 2B11 by Arylalkynes
    Elizabeth S. Roberts, Nancy Eddy Hopkins, Maryam Foroozesh, William L. Alworth, James R. Halpert and Paul F. Hollenberg
    Drug Metabolism and Disposition November 1997, 25 (11) 1242-1248;
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    Gender, Age and Dose Effects of Neonatally Administered Aspartate on the Sexually Dimorphic Plasma Growth Hormone Profiles Regulating Expression of the Rat Sex-Dependent Hepatic CYP Isoforms
    Arun K. Agrawal and Bernard H. Shapiro
    Drug Metabolism and Disposition November 1997, 25 (11) 1249-1256;
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    14C-Propoxyphene Demethylation in the Rat
    Yves Horsmans, Alain Saliez, Véronique Van Den Berge, Jean-Pierre Desager, André P. Geubel, Stanislas Pauwels and Luc Lambotte
    Drug Metabolism and Disposition November 1997, 25 (11) 1257-1259;
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    Use of the Deconvolution Principle in the Estimation of Absorption and Pre-systemic Intestinal Elimination of Drugs
    Yazdi K. Pithavala, Inmaculada Soria and Cheryl L. Zimmerman
    Drug Metabolism and Disposition November 1997, 25 (11) 1260-1265;
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    Formation of Guanoxabenz from Guanabenz in Human Liver
    Bernd Clement and Mark Demesmaeker
    Drug Metabolism and Disposition November 1997, 25 (11) 1266-1271;
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    Pharmacokinetics and Metabolism in Mice of a Phosphorothioate Oligonucleotide Antisense Inhibitor of C-raf-1 Kinase Expression
    Richard S. Geary, Janet M. Leeds, Jon Fitchett, Todd Burckin, Loanne Truong, Charles Spainhour, Moire Creek and Arthur A. Levin
    Drug Metabolism and Disposition November 1997, 25 (11) 1272-1281;
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    Metabolic Profiles of Montelukast Sodium (Singulair), a Potent Cysteinyl Leukotriene1 Receptor Antagonist, in Human Plasma and Bile
    S. K. Balani, X. Xu, V. Pratha, M. A. Koss, R. D. Amin, C. Dufresne, R. R. Miller, B. H. Arison, G. A. Doss, M. Chiba, A. Freeman, S. D. Holland, J. I. Schwartz, K. C. Lasseter, B. J. Gertz, J. I. Isenberg, J. D. Rogers, J. H. Lin and T. A. Baillie
    Drug Metabolism and Disposition November 1997, 25 (11) 1282-1287;
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    Metabolism and Excretion of a Novel Antianxiety Drug Candidate, CP-93,393, in Long Evans Rats
    Chandra Prakash and Victor Soliman
    Drug Metabolism and Disposition November 1997, 25 (11) 1288-1297;
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    Metabolism of the Antiandrogenic Drug (Flutamide) by Human CYP1A2
    Manjunath S. Shet, Michael McPhaul, Charles W. Fisher, Nancy R. Stallings and Ronald W. Estabrook
    Drug Metabolism and Disposition November 1997, 25 (11) 1298-1303;
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    Studies on the Interactions of Chiral Secondary Alcohols with Rat Hydroxysteroid Sulfotransferase STa
    Erden Banoglu and Michael W. Duffel
    Drug Metabolism and Disposition November 1997, 25 (11) 1304-1310;
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    Reversible Formation of Fatty Acid Esters of Budesonide, an Antiasthma Glucocorticoid, in Human Lung and Liver Microsomes
    Anders Tunek, Karin Sjödin and Gösta Hallström
    Drug Metabolism and Disposition November 1997, 25 (11) 1311-1317;
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    Synthesis and Reactivity of Coumarin 3,4-Epoxide
    Stephanie L. Born, Pedro A. Rodriguez, Cynthia L. Eddy and Lois D. Lehman-McKeeman
    Drug Metabolism and Disposition November 1997, 25 (11) 1318-1324;

Short Communication

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    Pharmacokinetics of Recombinant Human Insulin-Like Growth Factor-I in Diabetic Rats  
    Kazutaka Higaki, Yukihiro Matsumoto, Rika Fujimoto, Yuji Kurosaki and Toshikiro Kimura
    Drug Metabolism and Disposition November 1997, 25 (11) 1324-1327;
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Drug Metabolism and Disposition
Vol. 25, Issue 11
1 Nov 1997
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