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Research ArticleArticle

Metabolic Profiles of Montelukast Sodium (Singulair), a Potent Cysteinyl Leukotriene1 Receptor Antagonist, in Human Plasma and Bile

S. K. Balani, X. Xu, V. Pratha, M. A. Koss, R. D. Amin, C. Dufresne, R. R. Miller, B. H. Arison, G. A. Doss, M. Chiba, A. Freeman, S. D. Holland, J. I. Schwartz, K. C. Lasseter, B. J. Gertz, J. I. Isenberg, J. D. Rogers, J. H. Lin and T. A. Baillie
Drug Metabolism and Disposition November 1997, 25 (11) 1282-1287;
S. K. Balani
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X. Xu
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V. Pratha
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M. A. Koss
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R. D. Amin
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C. Dufresne
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R. R. Miller
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B. H. Arison
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G. A. Doss
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M. Chiba
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A. Freeman
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S. D. Holland
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J. I. Schwartz
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K. C. Lasseter
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B. J. Gertz
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J. I. Isenberg
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J. D. Rogers
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J. H. Lin
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T. A. Baillie
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Article Information

vol. 25 no. 11 1282-1287
PubMed 
9351905

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received April 2, 1997
  • Accepted July 15, 1997
  • Published online November 1, 1997.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. S. K. Balani1,
  2. X. Xu1,
  3. V. Pratha5,
  4. M. A. Koss5,
  5. R. D. Amin1,
  6. C. Dufresne3,
  7. R. R. Miller1,
  8. B. H. Arison1,
  9. G. A. Doss1,
  10. M. Chiba1,
  11. A. Freeman2,
  12. S. D. Holland2,
  13. J. I. Schwartz2,
  14. K. C. Lasseter4,
  15. B. J. Gertz2,
  16. J. I. Isenberg5,
  17. J. D. Rogers1,
  18. J. H. Lin1 and
  19. T. A. Baillie1
  1. Departments of 1Drug Metabolism (S.K.B., X.X., R.D.A., R.R.M., B.H.A., G.A.D., M.C., J.D.R., J.H.L., T.A.B.) and 2Clinical Pharmacology (A.F., S.D.H., J.I.S., B.J.G.), Merck Research Laboratories; 3Department of Medicinal Chemistry, Merck Frosst Centre for Therapeutics (C.D.); 4Clinical Pharmacology Associates (K.C.L.); and 5Department of Medicine, UCSD Medical Center at San Diego (V.P., M.A.K., J.I.I.), University of California, San Diego
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    1 Nov 1997
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    Research ArticleArticle

    Metabolic Profiles of Montelukast Sodium (Singulair), a Potent Cysteinyl Leukotriene1 Receptor Antagonist, in Human Plasma and Bile

    S. K. Balani, X. Xu, V. Pratha, M. A. Koss, R. D. Amin, C. Dufresne, R. R. Miller, B. H. Arison, G. A. Doss, M. Chiba, A. Freeman, S. D. Holland, J. I. Schwartz, K. C. Lasseter, B. J. Gertz, J. I. Isenberg, J. D. Rogers, J. H. Lin and T. A. Baillie
    Drug Metabolism and Disposition November 1, 1997, 25 (11) 1282-1287;

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    Research ArticleArticle

    Metabolic Profiles of Montelukast Sodium (Singulair), a Potent Cysteinyl Leukotriene1 Receptor Antagonist, in Human Plasma and Bile

    S. K. Balani, X. Xu, V. Pratha, M. A. Koss, R. D. Amin, C. Dufresne, R. R. Miller, B. H. Arison, G. A. Doss, M. Chiba, A. Freeman, S. D. Holland, J. I. Schwartz, K. C. Lasseter, B. J. Gertz, J. I. Isenberg, J. D. Rogers, J. H. Lin and T. A. Baillie
    Drug Metabolism and Disposition November 1, 1997, 25 (11) 1282-1287;
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