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Drug Metabolism & Disposition

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Table of Contents

December 01, 1997; Volume 25,Issue 12

Articles

  • You have access
    Oral Bioavailability and First-Pass Effects
    K. C. Kwan
    Drug Metabolism and Disposition December 1997, 25 (12) 1329-1336;
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    Effects of Probenecid on Brain-Cerebrospinal Fluid-Blood Distribution Kinetics of E-Δ2-Valproic Acid in Rabbits
    Jamie L. Scism, Karen M. Powers, Alan A. Artru, Anne C. Chambers, Lydia Lewis, Kimberly K. Adkison, Thomas F. Kalhorn and Danny D. Shen
    Drug Metabolism and Disposition December 1997, 25 (12) 1337-1346;
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    The Involvement of Cytochrome P450 3A4 in theN-Demethylation ofl-α-Acetylmethadol (LAAM), norLAAM, and Methadone
    David E. Moody, Mario E. Alburges, Robert J. Parker, Jerry M. Collins and John M. Strong
    Drug Metabolism and Disposition December 1997, 25 (12) 1347-1353;
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    Cytochrome P450 Isozymes Involved in Lisofylline Metabolism to Pentoxifylline in Human Liver Microsomes
    Sun H. Lee and John T. Slattery
    Drug Metabolism and Disposition December 1997, 25 (12) 1354-1358;
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    Nonspecific Binding to Microsomes: Impact on Scale-Up of in Vitro Intrinsic Clearance to Hepatic Clearance as Assessed Through Examination of Warfarin, Imipramine, and Propranolol
    R. Scott Obach
    Drug Metabolism and Disposition December 1997, 25 (12) 1359-1369;
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    Species Differences in Metabolism of Panomifene, an Analogue of Tamoxifen
    Katalin Monostory, Katalin Jemnitz, László Vereczkey and Gábor Czira
    Drug Metabolism and Disposition December 1997, 25 (12) 1370-1378;
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    Metabolism of Clozapine by cDNA-Expressed Human Cytochrome P450 Enzymes
    Kristian Linnet and Ole V. Olesen
    Drug Metabolism and Disposition December 1997, 25 (12) 1379-1382;
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    In Vitro Biotransformation and Identification of Human Cytochrome P450 Isozyme-Dependent Metabolism of Tazofelone
    Sekhar S. Surapaneni, Michael P. Clay, Larry A. Spangle, Jonathan W. Paschal and Terry D. Lindstrom
    Drug Metabolism and Disposition December 1997, 25 (12) 1383-1388;
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    Glucuronidation of Opioids, Carboxylic Acid-Containing Drugs, and Hydroxylated Xenobiotics Catalyzed by Expressed Monkey UDP-Glucuronosyltransferase 2B9 Protein
    Mitchell D. Green, Guy Bélanger, Dean W. Hum, Alain Bélanger and Thomas R. Tephly
    Drug Metabolism and Disposition December 1997, 25 (12) 1389-1394;
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    Metabolism and Excretion of a New Antianxiety Drug Candidate, CP-93,393, in Cynomolgus Monkeys
    Chandra Prakash and Donghui Cui
    Drug Metabolism and Disposition December 1997, 25 (12) 1395-1406;
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    Mechanism-Based Inactivation of Human Liver Cytochrome P450 2A6 by 8-Methoxypsoralen
    Luke L. Koenigs, Raimund M. Peter, Stella J. Thompson, Allan E. Rettie and William F. Trager
    Drug Metabolism and Disposition December 1997, 25 (12) 1407-1415;
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    Gadolinium Chloride Inhibition of Rat Hepatic Microsomal Epoxide Hydrolase and Glutathione S-Transferase Gene Expression
    Sang Geon Kim and Sung Hee Choi
    Drug Metabolism and Disposition December 1997, 25 (12) 1416-1423;
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    In Vitro and In Vivo Effects of the Arylamine Human Immunodeficiency Virus Protease Inhibitor 4R-(4α,5α,6β,7β)-1-[(3-(1-Imidazoylcarbamoyl)phenyl)methyl]-3-[(3-aminophenyl)methyl]hexahydro-5,6-dihydroxy-4,7-bis(phenylmethyl)-2H-1,3-diazepin-2-one (SD894) on Rat Hepatic Cytochrome P450 2B and 3A
    Mary F. Grubb, Sharon Diamond and David D. Christ
    Drug Metabolism and Disposition December 1997, 25 (12) 1424-1428;
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    Human Lymphocyte Cytochrome P450 2E1, a Putative Marker for Alcohol-Mediated Changes in Hepatic Chlorzoxazone Activity
    Judy L. Raucy, Eric D. Schultz, Mike R. Wester, Sanjeev Arora, David E. Johnston, John L. Omdahl and Susan P. Carpenter
    Drug Metabolism and Disposition December 1997, 25 (12) 1429-1435;
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    Relative Contribution of Human Erythrocyte Aldehyde Dehydrogenase to the Systemic Detoxification of the Oxazaphosphorines
    Patricia A. Dockham, Lakshmaiah Sreerama and Norman E. Sladek
    Drug Metabolism and Disposition December 1997, 25 (12) 1436-1441;

Short Communication

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    Induction of Rat Hepatic Cytochrome P450 2B Subfamily by Azidophenobarbital, as a Possible Photoaffinity Probe for the Putative Phenobarbital Receptor
    Taishi Shinohara, Ken-ichiro Taura, Tohru Imamura, Hideyuki Yamada and Kazuta Oguri
    Drug Metabolism and Disposition December 1997, 25 (12) 1442-1446;

Letter

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    9,13-Dicis-Retinoic Acid as an Isomerization Product of 9-cis-Retinoic Acid  
    Jörn Oliver Sass, Georg Tzimas and Heinz Nau
    Drug Metabolism and Disposition December 1997, 25 (12) 1447;

Erratum

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    Correction for vol. 24, p. 1340
    Drug Metabolism and Disposition December 1997, 25 (12) 1449;
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Drug Metabolism and Disposition
Vol. 25, Issue 12
1 Dec 1997
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