Table of Contents

Articles

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  Oral Bioavailability and First-Pass Effects

  K. C. Kwan

  Drug Metabolism and Disposition December 1997, 25 (12) 1329-1336;
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  Effects of Probenecid on Brain-Cerebrospinal Fluid-Blood Distribution Kinetics of E-Δ²-Valproic Acid in Rabbits

  Jamie L. Scism, Karen M. Powers, Alan A. Artru, Anne C. Chambers, Lydia Lewis, Kimberly K. Adkison, Thomas F. Kalhorn and Danny D. Shen

  Drug Metabolism and Disposition December 1997, 25 (12) 1337-1346;
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  The Involvement of Cytochrome P450 3A4 in theN-Demethylation ofl-α-Acetylmethadol (LAAM), norLAAM, and Methadone

  David E. Moody, Mario E. Alburges, Robert J. Parker, Jerry M. Collins and John M. Strong

  Drug Metabolism and Disposition December 1997, 25 (12) 1347-1353;
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  Cytochrome P450 Isozymes Involved in Lisofylline Metabolism to Pentoxifylline in Human Liver Microsomes

  Sun H. Lee and John T. Slattery

  Drug Metabolism and Disposition December 1997, 25 (12) 1354-1358;
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  Nonspecific Binding to Microsomes: Impact on Scale-Up of in Vitro Intrinsic Clearance to Hepatic Clearance as Assessed Through Examination of Warfarin, Imipramine, and Propranolol

  R. Scott Obach

  Drug Metabolism and Disposition December 1997, 25 (12) 1359-1369;
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  Species Differences in Metabolism of Panomifene, an Analogue of Tamoxifen

  Katalin Monostory, Katalin Jemnitz, László Vereczkey and Gábor Czira

  Drug Metabolism and Disposition December 1997, 25 (12) 1370-1378;
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  Metabolism of Clozapine by cDNA-Expressed Human Cytochrome P450 Enzymes

  Kristian Linnet and Ole V. Olesen

  Drug Metabolism and Disposition December 1997, 25 (12) 1379-1382;
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  In Vitro Biotransformation and Identification of Human Cytochrome P450 Isozyme-Dependent Metabolism of Tazofelone

  Sekhar S. Surapaneni, Michael P. Clay, Larry A. Spangle, Jonathan W. Paschal and Terry D. Lindstrom

  Drug Metabolism and Disposition December 1997, 25 (12) 1383-1388;
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  Glucuronidation of Opioids, Carboxylic Acid-Containing Drugs, and Hydroxylated Xenobiotics Catalyzed by Expressed Monkey UDP-Glucuronosyltransferase 2B9 Protein

  Mitchell D. Green, Guy Bélanger, Dean W. Hum, Alain Bélanger and Thomas R. Tephly

  Drug Metabolism and Disposition December 1997, 25 (12) 1389-1394;
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  Metabolism and Excretion of a New Antianxiety Drug Candidate, CP-93,393, in Cynomolgus Monkeys

  Chandra Prakash and Donghui Cui

  Drug Metabolism and Disposition December 1997, 25 (12) 1395-1406;
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  Mechanism-Based Inactivation of Human Liver Cytochrome P450 2A6 by 8-Methoxypsoralen

  Luke L. Koenigs, Raimund M. Peter, Stella J. Thompson, Allan E. Rettie and William F. Trager

  Drug Metabolism and Disposition December 1997, 25 (12) 1407-1415;
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  Gadolinium Chloride Inhibition of Rat Hepatic Microsomal Epoxide Hydrolase and Glutathione S-Transferase Gene Expression

  Sang Geon Kim and Sung Hee Choi

  Drug Metabolism and Disposition December 1997, 25 (12) 1416-1423;
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  In Vitro and In Vivo Effects of the Arylamine Human Immunodeficiency Virus Protease Inhibitor 4R-(4α,5α,6β,7β)-1-[(3-(1-Imidazoylcarbamoyl)phenyl)methyl]-3-[(3-aminophenyl)methyl]hexahydro-5,6-dihydroxy-4,7-bis(phenylmethyl)-2H-1,3-diazepin-2-one (SD894) on Rat Hepatic Cytochrome P450 2B and 3A

  Mary F. Grubb, Sharon Diamond and David D. Christ

  Drug Metabolism and Disposition December 1997, 25 (12) 1424-1428;
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  Human Lymphocyte Cytochrome P450 2E1, a Putative Marker for Alcohol-Mediated Changes in Hepatic Chlorzoxazone Activity

  Judy L. Raucy, Eric D. Schultz, Mike R. Wester, Sanjeev Arora, David E. Johnston, John L. Omdahl and Susan P. Carpenter

  Drug Metabolism and Disposition December 1997, 25 (12) 1429-1435;
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  Relative Contribution of Human Erythrocyte Aldehyde Dehydrogenase to the Systemic Detoxification of the Oxazaphosphorines

  Patricia A. Dockham, Lakshmaiah Sreerama and Norman E. Sladek

  Drug Metabolism and Disposition December 1997, 25 (12) 1436-1441;