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Research ArticleArticle

Nonspecific Binding to Microsomes: Impact on Scale-Up of in Vitro Intrinsic Clearance to Hepatic Clearance as Assessed Through Examination of Warfarin, Imipramine, and Propranolol

R. Scott Obach
Drug Metabolism and Disposition December 1997, 25 (12) 1359-1369;
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Research ArticleArticle

Nonspecific Binding to Microsomes: Impact on Scale-Up of in Vitro Intrinsic Clearance to Hepatic Clearance as Assessed Through Examination of Warfarin, Imipramine, and Propranolol

R. Scott Obach
Drug Metabolism and Disposition December 1, 1997, 25 (12) 1359-1369;
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