Table of Contents

Articles

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  Comparative Studies of In Vitro Inhibition of Cytochrome P450 3A4-Dependent Testosterone 6β-Hydroxylation by Roxithromycin and Its Metabolites, Troleandomycin, and Erythromycin

  Hiroshi Yamazaki and Tsutomu Shimada

  Drug Metabolism and Disposition November 1998, 26 (11) 1053-1057;
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  Tissue Distribution, Metabolism, and Clearance of the Convulsant Trimethylolpropane Phosphate in Rats

  John Rossi, Anne E. Jung, Glenn D. Ritchie, James W. Lindsey and Alan F. Nordholm

  Drug Metabolism and Disposition November 1998, 26 (11) 1058-1062;
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  Alterations of the Catalytic Activities of Drug-Metabolizing Enzymes in Cultures of Human Liver Slices

  Mark VandenBranden, Steven A. Wrighton, Sean Ekins, Jennifer S. Gillespie, Shelly N. Binkley, Barbara J. Ring, Melinda G. Gadberry, D. Charlene Mullins, Stephen C. Strom and Charles B. Jensen

  Drug Metabolism and Disposition November 1998, 26 (11) 1063-1068;
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  Metabolism and Excretion of Zafirlukast in Dogs, Rats, and Mice

  R. D. Savidge, K. H. Bui, B. K. Birmingham, J. L. Morse and R. C. Spreen

  Drug Metabolism and Disposition November 1998, 26 (11) 1069-1076;
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  Pharmacokinetics of the Bicyclic Peptide Tachykinin NK₂ Receptor Antagonist MEN 11420 (Nepadutant) in Rats

  Annalisa Lippi, Marco Criscuoli, Marco Guelfi, Paolo Santicioli and Carlo Alberto Maggi

  Drug Metabolism and Disposition November 1998, 26 (11) 1077-1081;
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  Effects of Fibrates on the Glycine Conjugation of Benzoic Acid in Rats

  Zoltán Gregus, Tibor Fekete, Éva Halászi, Ágnes Gyurasics and Curtis D. Klaassen

  Drug Metabolism and Disposition November 1998, 26 (11) 1082-1088;
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  Potentially Reactive Cyclic Carbamate Metabolite of the Antiepileptic Drug Felbamate Produced by Human Liver Tissue In Vitro

  Izet M. Kapetanovic, Cynthia D. Torchin, Charles D. Thompson, Thomas A. Miller, Patrick J. McNeilly, Timothy L. Macdonald, Harvey J. Kupferberg, James L. Perhach, R. Duane Sofia and John M. Strong

  Drug Metabolism and Disposition November 1998, 26 (11) 1089-1095;
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  1- and 3-Hydroxylations, in Addition to 4-Hydroxylation, of Debrisoquine Are Catalyzed by Cytochrome P450 2D6 in Humans

  Birgit Eiermann, Per Olof Edlund, Agneta Tjernberg, Per Dalén, Marja-Liisa Dahl and Leif Bertilsson

  Drug Metabolism and Disposition November 1998, 26 (11) 1096-1101;
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  In Vitro and In Vivo Metabolism of the Progestagen Org 30659 in Several Species

  C. H. J. Verhoeven, S. F. M. Krebbers, G. N. Wagenaars, C. J. Booy, G. M. M. Groothuis, P. Olinga and R. M. E. Vos

  Drug Metabolism and Disposition November 1998, 26 (11) 1102-1112;
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  Hepatobiliary Transport Kinetics of HSR-903, a New Quinolone Antibacterial Agent

  Mitsuo Murata, Ikumi Tamai, Yoshimichi Sai, Osamu Nagata, Hideo Kato, Yuichi Sugiyama and Akira Tsuji

  Drug Metabolism and Disposition November 1998, 26 (11) 1113-1119;
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  Predicting the Oral Bioavailability of 19-Nortestosterone Progestins In Vivo from Their Metabolic Stability in Human Liver Microsomal Preparations In Vitro

  Wilhelm Kuhnz and Hille Gieschen

  Drug Metabolism and Disposition November 1998, 26 (11) 1120-1127;
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  Dose-Dependent Effects of PSC 833 on Its Tissue Distribution and on the Biliary Excretion of Endogenous Substrates in Rats

  SaeHeum Song, Hiroshi Suzuki, Ryosei Kawai, Chiaki Tanaka, Izumi Akasaka and Yuichi Sugiyama

  Drug Metabolism and Disposition November 1998, 26 (11) 1128-1133;
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  Pharmacokinetics and Metabolism of [¹⁴C]Dichloroacetate in Male Sprague-Dawley Rats

  Margaret O. James, Zimeng Yan, Rachel Cornett, V. Murali K. M. Jayanti, George N. Henderson, Natalia Davydova, Michael J. Katovich, Brad Pollock and Peter W. Stacpoole

  Drug Metabolism and Disposition November 1998, 26 (11) 1134-1143;
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  Transport of the β-Lactam Antibiotic Benzylpenicillin and the Dipeptide Glycylsarcosine by Brain Capillary Endothelial Cells In Vitro

  Michael Török, Jörg Huwyler, Jürgen Drewe, Heike Gutmann and Gert Fricker

  Drug Metabolism and Disposition November 1998, 26 (11) 1144-1148;
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  Tissue Distribution and Biotransformation of Zopolrestat, an Aldose Reductase Inhibitor, in Rats

  Richard P. Schneider, Hassan G. Fouda and Philip B. Inskeep

  Drug Metabolism and Disposition November 1998, 26 (11) 1149-1159;
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  Bioavailability, Multiple-Dose Pharmacokinetics, and Biotransformation of the Aldose Reductase Inhibitor Zopolrestat in Dogs

  Richard P. Schneider, Cynthia J. Davenport, Keith A. Hoffmaster and Philip B. Inskeep

  Drug Metabolism and Disposition November 1998, 26 (11) 1160-1166;