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Drug Metabolism & Disposition

Advanced Search

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  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
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Index by author

November 01, 1998; Volume 26,Issue 11
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Akasaka, Izumi

    1. You have access
      Dose-Dependent Effects of PSC 833 on Its Tissue Distribution and on the Biliary Excretion of Endogenous Substrates in Rats
      SaeHeum Song, Hiroshi Suzuki, Ryosei Kawai, Chiaki Tanaka, Izumi Akasaka and Yuichi Sugiyama
      Drug Metabolism and Disposition November 1998, 26 (11) 1128-1133;

B

  1. Bertilsson, Leif

    1. You have access
      1- and 3-Hydroxylations, in Addition to 4-Hydroxylation, of Debrisoquine Are Catalyzed by Cytochrome P450 2D6 in Humans
      Birgit Eiermann, Per Olof Edlund, Agneta Tjernberg, Per Dalén, Marja-Liisa Dahl and Leif Bertilsson
      Drug Metabolism and Disposition November 1998, 26 (11) 1096-1101;
  2. Binkley, Shelly N.

    1. You have access
      Alterations of the Catalytic Activities of Drug-Metabolizing Enzymes in Cultures of Human Liver Slices
      Mark VandenBranden, Steven A. Wrighton, Sean Ekins, Jennifer S. Gillespie, Shelly N. Binkley, Barbara J. Ring, Melinda G. Gadberry, D. Charlene Mullins, Stephen C. Strom and Charles B. Jensen
      Drug Metabolism and Disposition November 1998, 26 (11) 1063-1068;
  3. Birmingham, B. K.

    1. You have access
      Metabolism and Excretion of Zafirlukast in Dogs, Rats, and Mice
      R. D. Savidge, K. H. Bui, B. K. Birmingham, J. L. Morse and R. C. Spreen
      Drug Metabolism and Disposition November 1998, 26 (11) 1069-1076;
  4. Booy, C. J.

    1. You have access
      In Vitro and In Vivo Metabolism of the Progestagen Org 30659 in Several Species
      C. H. J. Verhoeven, S. F. M. Krebbers, G. N. Wagenaars, C. J. Booy, G. M. M. Groothuis, P. Olinga and R. M. E. Vos
      Drug Metabolism and Disposition November 1998, 26 (11) 1102-1112;
  5. Bui, K. H.

    1. You have access
      Metabolism and Excretion of Zafirlukast in Dogs, Rats, and Mice
      R. D. Savidge, K. H. Bui, B. K. Birmingham, J. L. Morse and R. C. Spreen
      Drug Metabolism and Disposition November 1998, 26 (11) 1069-1076;

C

  1. Cornett, Rachel

    1. You have access
      Pharmacokinetics and Metabolism of [14C]Dichloroacetate in Male Sprague-Dawley Rats
      Margaret O. James, Zimeng Yan, Rachel Cornett, V. Murali K. M. Jayanti, George N. Henderson, Natalia Davydova, Michael J. Katovich, Brad Pollock and Peter W. Stacpoole
      Drug Metabolism and Disposition November 1998, 26 (11) 1134-1143;
  2. Criscuoli, Marco

    1. You have access
      Pharmacokinetics of the Bicyclic Peptide Tachykinin NK2 Receptor Antagonist MEN 11420 (Nepadutant) in Rats
      Annalisa Lippi, Marco Criscuoli, Marco Guelfi, Paolo Santicioli and Carlo Alberto Maggi
      Drug Metabolism and Disposition November 1998, 26 (11) 1077-1081;

D

  1. Dahl, Marja-Liisa

    1. You have access
      1- and 3-Hydroxylations, in Addition to 4-Hydroxylation, of Debrisoquine Are Catalyzed by Cytochrome P450 2D6 in Humans
      Birgit Eiermann, Per Olof Edlund, Agneta Tjernberg, Per Dalén, Marja-Liisa Dahl and Leif Bertilsson
      Drug Metabolism and Disposition November 1998, 26 (11) 1096-1101;
  2. Dalén, Per

    1. You have access
      1- and 3-Hydroxylations, in Addition to 4-Hydroxylation, of Debrisoquine Are Catalyzed by Cytochrome P450 2D6 in Humans
      Birgit Eiermann, Per Olof Edlund, Agneta Tjernberg, Per Dalén, Marja-Liisa Dahl and Leif Bertilsson
      Drug Metabolism and Disposition November 1998, 26 (11) 1096-1101;
  3. Davenport, Cynthia J.

    1. You have access
      Bioavailability, Multiple-Dose Pharmacokinetics, and Biotransformation of the Aldose Reductase Inhibitor Zopolrestat in Dogs
      Richard P. Schneider, Cynthia J. Davenport, Keith A. Hoffmaster and Philip B. Inskeep
      Drug Metabolism and Disposition November 1998, 26 (11) 1160-1166;
  4. Davydova, Natalia

    1. You have access
      Pharmacokinetics and Metabolism of [14C]Dichloroacetate in Male Sprague-Dawley Rats
      Margaret O. James, Zimeng Yan, Rachel Cornett, V. Murali K. M. Jayanti, George N. Henderson, Natalia Davydova, Michael J. Katovich, Brad Pollock and Peter W. Stacpoole
      Drug Metabolism and Disposition November 1998, 26 (11) 1134-1143;
  5. Drewe, Jürgen

    1. You have access
      Transport of the β-Lactam Antibiotic Benzylpenicillin and the Dipeptide Glycylsarcosine by Brain Capillary Endothelial Cells In Vitro
      Michael Török, Jörg Huwyler, Jürgen Drewe, Heike Gutmann and Gert Fricker
      Drug Metabolism and Disposition November 1998, 26 (11) 1144-1148;

E

  1. Edlund, Per Olof

    1. You have access
      1- and 3-Hydroxylations, in Addition to 4-Hydroxylation, of Debrisoquine Are Catalyzed by Cytochrome P450 2D6 in Humans
      Birgit Eiermann, Per Olof Edlund, Agneta Tjernberg, Per Dalén, Marja-Liisa Dahl and Leif Bertilsson
      Drug Metabolism and Disposition November 1998, 26 (11) 1096-1101;
  2. Eiermann, Birgit

    1. You have access
      1- and 3-Hydroxylations, in Addition to 4-Hydroxylation, of Debrisoquine Are Catalyzed by Cytochrome P450 2D6 in Humans
      Birgit Eiermann, Per Olof Edlund, Agneta Tjernberg, Per Dalén, Marja-Liisa Dahl and Leif Bertilsson
      Drug Metabolism and Disposition November 1998, 26 (11) 1096-1101;
  3. Ekins, Sean

    1. You have access
      Alterations of the Catalytic Activities of Drug-Metabolizing Enzymes in Cultures of Human Liver Slices
      Mark VandenBranden, Steven A. Wrighton, Sean Ekins, Jennifer S. Gillespie, Shelly N. Binkley, Barbara J. Ring, Melinda G. Gadberry, D. Charlene Mullins, Stephen C. Strom and Charles B. Jensen
      Drug Metabolism and Disposition November 1998, 26 (11) 1063-1068;

F

  1. Fekete, Tibor

    1. You have access
      Effects of Fibrates on the Glycine Conjugation of Benzoic Acid in Rats
      Zoltán Gregus, Tibor Fekete, Éva Halászi, Ágnes Gyurasics and Curtis D. Klaassen
      Drug Metabolism and Disposition November 1998, 26 (11) 1082-1088;
  2. Fouda, Hassan G.

    1. You have access
      Tissue Distribution and Biotransformation of Zopolrestat, an Aldose Reductase Inhibitor, in Rats
      Richard P. Schneider, Hassan G. Fouda and Philip B. Inskeep
      Drug Metabolism and Disposition November 1998, 26 (11) 1149-1159;
  3. Fricker, Gert

    1. You have access
      Transport of the β-Lactam Antibiotic Benzylpenicillin and the Dipeptide Glycylsarcosine by Brain Capillary Endothelial Cells In Vitro
      Michael Török, Jörg Huwyler, Jürgen Drewe, Heike Gutmann and Gert Fricker
      Drug Metabolism and Disposition November 1998, 26 (11) 1144-1148;

G

  1. Gadberry, Melinda G.

    1. You have access
      Alterations of the Catalytic Activities of Drug-Metabolizing Enzymes in Cultures of Human Liver Slices
      Mark VandenBranden, Steven A. Wrighton, Sean Ekins, Jennifer S. Gillespie, Shelly N. Binkley, Barbara J. Ring, Melinda G. Gadberry, D. Charlene Mullins, Stephen C. Strom and Charles B. Jensen
      Drug Metabolism and Disposition November 1998, 26 (11) 1063-1068;
  2. Gieschen, Hille

    1. You have access
      Predicting the Oral Bioavailability of 19-Nortestosterone Progestins In Vivo from Their Metabolic Stability in Human Liver Microsomal Preparations In Vitro
      Wilhelm Kuhnz and Hille Gieschen
      Drug Metabolism and Disposition November 1998, 26 (11) 1120-1127;
  3. Gillespie, Jennifer S.

    1. You have access
      Alterations of the Catalytic Activities of Drug-Metabolizing Enzymes in Cultures of Human Liver Slices
      Mark VandenBranden, Steven A. Wrighton, Sean Ekins, Jennifer S. Gillespie, Shelly N. Binkley, Barbara J. Ring, Melinda G. Gadberry, D. Charlene Mullins, Stephen C. Strom and Charles B. Jensen
      Drug Metabolism and Disposition November 1998, 26 (11) 1063-1068;
  4. Gregus, Zoltán

    1. You have access
      Effects of Fibrates on the Glycine Conjugation of Benzoic Acid in Rats
      Zoltán Gregus, Tibor Fekete, Éva Halászi, Ágnes Gyurasics and Curtis D. Klaassen
      Drug Metabolism and Disposition November 1998, 26 (11) 1082-1088;
  5. Groothuis, G. M. M.

    1. You have access
      In Vitro and In Vivo Metabolism of the Progestagen Org 30659 in Several Species
      C. H. J. Verhoeven, S. F. M. Krebbers, G. N. Wagenaars, C. J. Booy, G. M. M. Groothuis, P. Olinga and R. M. E. Vos
      Drug Metabolism and Disposition November 1998, 26 (11) 1102-1112;
  6. Guelfi, Marco

    1. You have access
      Pharmacokinetics of the Bicyclic Peptide Tachykinin NK2 Receptor Antagonist MEN 11420 (Nepadutant) in Rats
      Annalisa Lippi, Marco Criscuoli, Marco Guelfi, Paolo Santicioli and Carlo Alberto Maggi
      Drug Metabolism and Disposition November 1998, 26 (11) 1077-1081;
  7. Gutmann, Heike

    1. You have access
      Transport of the β-Lactam Antibiotic Benzylpenicillin and the Dipeptide Glycylsarcosine by Brain Capillary Endothelial Cells In Vitro
      Michael Török, Jörg Huwyler, Jürgen Drewe, Heike Gutmann and Gert Fricker
      Drug Metabolism and Disposition November 1998, 26 (11) 1144-1148;
  8. Gyurasics, Ágnes

    1. You have access
      Effects of Fibrates on the Glycine Conjugation of Benzoic Acid in Rats
      Zoltán Gregus, Tibor Fekete, Éva Halászi, Ágnes Gyurasics and Curtis D. Klaassen
      Drug Metabolism and Disposition November 1998, 26 (11) 1082-1088;

H

  1. Halászi, Éva

    1. You have access
      Effects of Fibrates on the Glycine Conjugation of Benzoic Acid in Rats
      Zoltán Gregus, Tibor Fekete, Éva Halászi, Ágnes Gyurasics and Curtis D. Klaassen
      Drug Metabolism and Disposition November 1998, 26 (11) 1082-1088;
  2. Henderson, George N.

    1. You have access
      Pharmacokinetics and Metabolism of [14C]Dichloroacetate in Male Sprague-Dawley Rats
      Margaret O. James, Zimeng Yan, Rachel Cornett, V. Murali K. M. Jayanti, George N. Henderson, Natalia Davydova, Michael J. Katovich, Brad Pollock and Peter W. Stacpoole
      Drug Metabolism and Disposition November 1998, 26 (11) 1134-1143;
  3. Hoffmaster, Keith A.

    1. You have access
      Bioavailability, Multiple-Dose Pharmacokinetics, and Biotransformation of the Aldose Reductase Inhibitor Zopolrestat in Dogs
      Richard P. Schneider, Cynthia J. Davenport, Keith A. Hoffmaster and Philip B. Inskeep
      Drug Metabolism and Disposition November 1998, 26 (11) 1160-1166;
  4. Huwyler, Jörg

    1. You have access
      Transport of the β-Lactam Antibiotic Benzylpenicillin and the Dipeptide Glycylsarcosine by Brain Capillary Endothelial Cells In Vitro
      Michael Török, Jörg Huwyler, Jürgen Drewe, Heike Gutmann and Gert Fricker
      Drug Metabolism and Disposition November 1998, 26 (11) 1144-1148;

I

  1. Inskeep, Philip B.

    1. You have access
      Tissue Distribution and Biotransformation of Zopolrestat, an Aldose Reductase Inhibitor, in Rats
      Richard P. Schneider, Hassan G. Fouda and Philip B. Inskeep
      Drug Metabolism and Disposition November 1998, 26 (11) 1149-1159;
    2. You have access
      Bioavailability, Multiple-Dose Pharmacokinetics, and Biotransformation of the Aldose Reductase Inhibitor Zopolrestat in Dogs
      Richard P. Schneider, Cynthia J. Davenport, Keith A. Hoffmaster and Philip B. Inskeep
      Drug Metabolism and Disposition November 1998, 26 (11) 1160-1166;

J

  1. James, Margaret O.

    1. You have access
      Pharmacokinetics and Metabolism of [14C]Dichloroacetate in Male Sprague-Dawley Rats
      Margaret O. James, Zimeng Yan, Rachel Cornett, V. Murali K. M. Jayanti, George N. Henderson, Natalia Davydova, Michael J. Katovich, Brad Pollock and Peter W. Stacpoole
      Drug Metabolism and Disposition November 1998, 26 (11) 1134-1143;
  2. Jayanti, V. Murali K. M.

    1. You have access
      Pharmacokinetics and Metabolism of [14C]Dichloroacetate in Male Sprague-Dawley Rats
      Margaret O. James, Zimeng Yan, Rachel Cornett, V. Murali K. M. Jayanti, George N. Henderson, Natalia Davydova, Michael J. Katovich, Brad Pollock and Peter W. Stacpoole
      Drug Metabolism and Disposition November 1998, 26 (11) 1134-1143;
  3. Jensen, Charles B.

    1. You have access
      Alterations of the Catalytic Activities of Drug-Metabolizing Enzymes in Cultures of Human Liver Slices
      Mark VandenBranden, Steven A. Wrighton, Sean Ekins, Jennifer S. Gillespie, Shelly N. Binkley, Barbara J. Ring, Melinda G. Gadberry, D. Charlene Mullins, Stephen C. Strom and Charles B. Jensen
      Drug Metabolism and Disposition November 1998, 26 (11) 1063-1068;
  4. Jung, Anne E.

    1. You have access
      Tissue Distribution, Metabolism, and Clearance of the Convulsant Trimethylolpropane Phosphate in Rats
      John Rossi, Anne E. Jung, Glenn D. Ritchie, James W. Lindsey and Alan F. Nordholm
      Drug Metabolism and Disposition November 1998, 26 (11) 1058-1062;

K

  1. Kapetanovic, Izet M.

    1. You have access
      Potentially Reactive Cyclic Carbamate Metabolite of the Antiepileptic Drug Felbamate Produced by Human Liver Tissue In Vitro
      Izet M. Kapetanovic, Cynthia D. Torchin, Charles D. Thompson, Thomas A. Miller, Patrick J. McNeilly, Timothy L. Macdonald, Harvey J. Kupferberg, James L. Perhach, R. Duane Sofia and John M. Strong
      Drug Metabolism and Disposition November 1998, 26 (11) 1089-1095;
  2. Kato, Hideo

    1. You have access
      Hepatobiliary Transport Kinetics of HSR-903, a New Quinolone Antibacterial Agent
      Mitsuo Murata, Ikumi Tamai, Yoshimichi Sai, Osamu Nagata, Hideo Kato, Yuichi Sugiyama and Akira Tsuji
      Drug Metabolism and Disposition November 1998, 26 (11) 1113-1119;
  3. Katovich, Michael J.

    1. You have access
      Pharmacokinetics and Metabolism of [14C]Dichloroacetate in Male Sprague-Dawley Rats
      Margaret O. James, Zimeng Yan, Rachel Cornett, V. Murali K. M. Jayanti, George N. Henderson, Natalia Davydova, Michael J. Katovich, Brad Pollock and Peter W. Stacpoole
      Drug Metabolism and Disposition November 1998, 26 (11) 1134-1143;
  4. Kawai, Ryosei

    1. You have access
      Dose-Dependent Effects of PSC 833 on Its Tissue Distribution and on the Biliary Excretion of Endogenous Substrates in Rats
      SaeHeum Song, Hiroshi Suzuki, Ryosei Kawai, Chiaki Tanaka, Izumi Akasaka and Yuichi Sugiyama
      Drug Metabolism and Disposition November 1998, 26 (11) 1128-1133;
  5. Klaassen, Curtis D.

    1. You have access
      Effects of Fibrates on the Glycine Conjugation of Benzoic Acid in Rats
      Zoltán Gregus, Tibor Fekete, Éva Halászi, Ágnes Gyurasics and Curtis D. Klaassen
      Drug Metabolism and Disposition November 1998, 26 (11) 1082-1088;
  6. Krebbers, S. F. M.

    1. You have access
      In Vitro and In Vivo Metabolism of the Progestagen Org 30659 in Several Species
      C. H. J. Verhoeven, S. F. M. Krebbers, G. N. Wagenaars, C. J. Booy, G. M. M. Groothuis, P. Olinga and R. M. E. Vos
      Drug Metabolism and Disposition November 1998, 26 (11) 1102-1112;
  7. Kuhnz, Wilhelm

    1. You have access
      Predicting the Oral Bioavailability of 19-Nortestosterone Progestins In Vivo from Their Metabolic Stability in Human Liver Microsomal Preparations In Vitro
      Wilhelm Kuhnz and Hille Gieschen
      Drug Metabolism and Disposition November 1998, 26 (11) 1120-1127;
  8. Kupferberg, Harvey J.

    1. You have access
      Potentially Reactive Cyclic Carbamate Metabolite of the Antiepileptic Drug Felbamate Produced by Human Liver Tissue In Vitro
      Izet M. Kapetanovic, Cynthia D. Torchin, Charles D. Thompson, Thomas A. Miller, Patrick J. McNeilly, Timothy L. Macdonald, Harvey J. Kupferberg, James L. Perhach, R. Duane Sofia and John M. Strong
      Drug Metabolism and Disposition November 1998, 26 (11) 1089-1095;

L

  1. Lindsey, James W.

    1. You have access
      Tissue Distribution, Metabolism, and Clearance of the Convulsant Trimethylolpropane Phosphate in Rats
      John Rossi, Anne E. Jung, Glenn D. Ritchie, James W. Lindsey and Alan F. Nordholm
      Drug Metabolism and Disposition November 1998, 26 (11) 1058-1062;
  2. Lippi, Annalisa

    1. You have access
      Pharmacokinetics of the Bicyclic Peptide Tachykinin NK2 Receptor Antagonist MEN 11420 (Nepadutant) in Rats
      Annalisa Lippi, Marco Criscuoli, Marco Guelfi, Paolo Santicioli and Carlo Alberto Maggi
      Drug Metabolism and Disposition November 1998, 26 (11) 1077-1081;

M

  1. Macdonald, Timothy L.

    1. You have access
      Potentially Reactive Cyclic Carbamate Metabolite of the Antiepileptic Drug Felbamate Produced by Human Liver Tissue In Vitro
      Izet M. Kapetanovic, Cynthia D. Torchin, Charles D. Thompson, Thomas A. Miller, Patrick J. McNeilly, Timothy L. Macdonald, Harvey J. Kupferberg, James L. Perhach, R. Duane Sofia and John M. Strong
      Drug Metabolism and Disposition November 1998, 26 (11) 1089-1095;
  2. Maggi, Carlo Alberto

    1. You have access
      Pharmacokinetics of the Bicyclic Peptide Tachykinin NK2 Receptor Antagonist MEN 11420 (Nepadutant) in Rats
      Annalisa Lippi, Marco Criscuoli, Marco Guelfi, Paolo Santicioli and Carlo Alberto Maggi
      Drug Metabolism and Disposition November 1998, 26 (11) 1077-1081;
  3. McNeilly, Patrick J.

    1. You have access
      Potentially Reactive Cyclic Carbamate Metabolite of the Antiepileptic Drug Felbamate Produced by Human Liver Tissue In Vitro
      Izet M. Kapetanovic, Cynthia D. Torchin, Charles D. Thompson, Thomas A. Miller, Patrick J. McNeilly, Timothy L. Macdonald, Harvey J. Kupferberg, James L. Perhach, R. Duane Sofia and John M. Strong
      Drug Metabolism and Disposition November 1998, 26 (11) 1089-1095;
  4. Miller, Thomas A.

    1. You have access
      Potentially Reactive Cyclic Carbamate Metabolite of the Antiepileptic Drug Felbamate Produced by Human Liver Tissue In Vitro
      Izet M. Kapetanovic, Cynthia D. Torchin, Charles D. Thompson, Thomas A. Miller, Patrick J. McNeilly, Timothy L. Macdonald, Harvey J. Kupferberg, James L. Perhach, R. Duane Sofia and John M. Strong
      Drug Metabolism and Disposition November 1998, 26 (11) 1089-1095;
  5. Morse, J. L.

    1. You have access
      Metabolism and Excretion of Zafirlukast in Dogs, Rats, and Mice
      R. D. Savidge, K. H. Bui, B. K. Birmingham, J. L. Morse and R. C. Spreen
      Drug Metabolism and Disposition November 1998, 26 (11) 1069-1076;
  6. Mullins, D. Charlene

    1. You have access
      Alterations of the Catalytic Activities of Drug-Metabolizing Enzymes in Cultures of Human Liver Slices
      Mark VandenBranden, Steven A. Wrighton, Sean Ekins, Jennifer S. Gillespie, Shelly N. Binkley, Barbara J. Ring, Melinda G. Gadberry, D. Charlene Mullins, Stephen C. Strom and Charles B. Jensen
      Drug Metabolism and Disposition November 1998, 26 (11) 1063-1068;
  7. Murata, Mitsuo

    1. You have access
      Hepatobiliary Transport Kinetics of HSR-903, a New Quinolone Antibacterial Agent
      Mitsuo Murata, Ikumi Tamai, Yoshimichi Sai, Osamu Nagata, Hideo Kato, Yuichi Sugiyama and Akira Tsuji
      Drug Metabolism and Disposition November 1998, 26 (11) 1113-1119;

N

  1. Nagata, Osamu

    1. You have access
      Hepatobiliary Transport Kinetics of HSR-903, a New Quinolone Antibacterial Agent
      Mitsuo Murata, Ikumi Tamai, Yoshimichi Sai, Osamu Nagata, Hideo Kato, Yuichi Sugiyama and Akira Tsuji
      Drug Metabolism and Disposition November 1998, 26 (11) 1113-1119;
  2. Nordholm, Alan F.

    1. You have access
      Tissue Distribution, Metabolism, and Clearance of the Convulsant Trimethylolpropane Phosphate in Rats
      John Rossi, Anne E. Jung, Glenn D. Ritchie, James W. Lindsey and Alan F. Nordholm
      Drug Metabolism and Disposition November 1998, 26 (11) 1058-1062;

O

  1. Olinga, P.

    1. You have access
      In Vitro and In Vivo Metabolism of the Progestagen Org 30659 in Several Species
      C. H. J. Verhoeven, S. F. M. Krebbers, G. N. Wagenaars, C. J. Booy, G. M. M. Groothuis, P. Olinga and R. M. E. Vos
      Drug Metabolism and Disposition November 1998, 26 (11) 1102-1112;

P

  1. Perhach, James L.

    1. You have access
      Potentially Reactive Cyclic Carbamate Metabolite of the Antiepileptic Drug Felbamate Produced by Human Liver Tissue In Vitro
      Izet M. Kapetanovic, Cynthia D. Torchin, Charles D. Thompson, Thomas A. Miller, Patrick J. McNeilly, Timothy L. Macdonald, Harvey J. Kupferberg, James L. Perhach, R. Duane Sofia and John M. Strong
      Drug Metabolism and Disposition November 1998, 26 (11) 1089-1095;
  2. Pollock, Brad

    1. You have access
      Pharmacokinetics and Metabolism of [14C]Dichloroacetate in Male Sprague-Dawley Rats
      Margaret O. James, Zimeng Yan, Rachel Cornett, V. Murali K. M. Jayanti, George N. Henderson, Natalia Davydova, Michael J. Katovich, Brad Pollock and Peter W. Stacpoole
      Drug Metabolism and Disposition November 1998, 26 (11) 1134-1143;

R

  1. Ring, Barbara J.

    1. You have access
      Alterations of the Catalytic Activities of Drug-Metabolizing Enzymes in Cultures of Human Liver Slices
      Mark VandenBranden, Steven A. Wrighton, Sean Ekins, Jennifer S. Gillespie, Shelly N. Binkley, Barbara J. Ring, Melinda G. Gadberry, D. Charlene Mullins, Stephen C. Strom and Charles B. Jensen
      Drug Metabolism and Disposition November 1998, 26 (11) 1063-1068;
  2. Ritchie, Glenn D.

    1. You have access
      Tissue Distribution, Metabolism, and Clearance of the Convulsant Trimethylolpropane Phosphate in Rats
      John Rossi, Anne E. Jung, Glenn D. Ritchie, James W. Lindsey and Alan F. Nordholm
      Drug Metabolism and Disposition November 1998, 26 (11) 1058-1062;
  3. Rossi, John

    1. You have access
      Tissue Distribution, Metabolism, and Clearance of the Convulsant Trimethylolpropane Phosphate in Rats
      John Rossi, Anne E. Jung, Glenn D. Ritchie, James W. Lindsey and Alan F. Nordholm
      Drug Metabolism and Disposition November 1998, 26 (11) 1058-1062;

S

  1. Sai, Yoshimichi

    1. You have access
      Hepatobiliary Transport Kinetics of HSR-903, a New Quinolone Antibacterial Agent
      Mitsuo Murata, Ikumi Tamai, Yoshimichi Sai, Osamu Nagata, Hideo Kato, Yuichi Sugiyama and Akira Tsuji
      Drug Metabolism and Disposition November 1998, 26 (11) 1113-1119;
  2. Santicioli, Paolo

    1. You have access
      Pharmacokinetics of the Bicyclic Peptide Tachykinin NK2 Receptor Antagonist MEN 11420 (Nepadutant) in Rats
      Annalisa Lippi, Marco Criscuoli, Marco Guelfi, Paolo Santicioli and Carlo Alberto Maggi
      Drug Metabolism and Disposition November 1998, 26 (11) 1077-1081;
  3. Savidge, R. D.

    1. You have access
      Metabolism and Excretion of Zafirlukast in Dogs, Rats, and Mice
      R. D. Savidge, K. H. Bui, B. K. Birmingham, J. L. Morse and R. C. Spreen
      Drug Metabolism and Disposition November 1998, 26 (11) 1069-1076;
  4. Schneider, Richard P.

    1. You have access
      Tissue Distribution and Biotransformation of Zopolrestat, an Aldose Reductase Inhibitor, in Rats
      Richard P. Schneider, Hassan G. Fouda and Philip B. Inskeep
      Drug Metabolism and Disposition November 1998, 26 (11) 1149-1159;
    2. You have access
      Bioavailability, Multiple-Dose Pharmacokinetics, and Biotransformation of the Aldose Reductase Inhibitor Zopolrestat in Dogs
      Richard P. Schneider, Cynthia J. Davenport, Keith A. Hoffmaster and Philip B. Inskeep
      Drug Metabolism and Disposition November 1998, 26 (11) 1160-1166;
  5. Shimada, Tsutomu

    1. You have access
      Comparative Studies of In Vitro Inhibition of Cytochrome P450 3A4-Dependent Testosterone 6β-Hydroxylation by Roxithromycin and Its Metabolites, Troleandomycin, and Erythromycin
      Hiroshi Yamazaki and Tsutomu Shimada
      Drug Metabolism and Disposition November 1998, 26 (11) 1053-1057;
  6. Sofia, R. Duane

    1. You have access
      Potentially Reactive Cyclic Carbamate Metabolite of the Antiepileptic Drug Felbamate Produced by Human Liver Tissue In Vitro
      Izet M. Kapetanovic, Cynthia D. Torchin, Charles D. Thompson, Thomas A. Miller, Patrick J. McNeilly, Timothy L. Macdonald, Harvey J. Kupferberg, James L. Perhach, R. Duane Sofia and John M. Strong
      Drug Metabolism and Disposition November 1998, 26 (11) 1089-1095;
  7. Song, SaeHeum

    1. You have access
      Dose-Dependent Effects of PSC 833 on Its Tissue Distribution and on the Biliary Excretion of Endogenous Substrates in Rats
      SaeHeum Song, Hiroshi Suzuki, Ryosei Kawai, Chiaki Tanaka, Izumi Akasaka and Yuichi Sugiyama
      Drug Metabolism and Disposition November 1998, 26 (11) 1128-1133;
  8. Spreen, R. C.

    1. You have access
      Metabolism and Excretion of Zafirlukast in Dogs, Rats, and Mice
      R. D. Savidge, K. H. Bui, B. K. Birmingham, J. L. Morse and R. C. Spreen
      Drug Metabolism and Disposition November 1998, 26 (11) 1069-1076;
  9. Stacpoole, Peter W.

    1. You have access
      Pharmacokinetics and Metabolism of [14C]Dichloroacetate in Male Sprague-Dawley Rats
      Margaret O. James, Zimeng Yan, Rachel Cornett, V. Murali K. M. Jayanti, George N. Henderson, Natalia Davydova, Michael J. Katovich, Brad Pollock and Peter W. Stacpoole
      Drug Metabolism and Disposition November 1998, 26 (11) 1134-1143;
  10. Strom, Stephen C.

    1. You have access
      Alterations of the Catalytic Activities of Drug-Metabolizing Enzymes in Cultures of Human Liver Slices
      Mark VandenBranden, Steven A. Wrighton, Sean Ekins, Jennifer S. Gillespie, Shelly N. Binkley, Barbara J. Ring, Melinda G. Gadberry, D. Charlene Mullins, Stephen C. Strom and Charles B. Jensen
      Drug Metabolism and Disposition November 1998, 26 (11) 1063-1068;
  11. Strong, John M.

    1. You have access
      Potentially Reactive Cyclic Carbamate Metabolite of the Antiepileptic Drug Felbamate Produced by Human Liver Tissue In Vitro
      Izet M. Kapetanovic, Cynthia D. Torchin, Charles D. Thompson, Thomas A. Miller, Patrick J. McNeilly, Timothy L. Macdonald, Harvey J. Kupferberg, James L. Perhach, R. Duane Sofia and John M. Strong
      Drug Metabolism and Disposition November 1998, 26 (11) 1089-1095;
  12. Sugiyama, Yuichi

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      Hepatobiliary Transport Kinetics of HSR-903, a New Quinolone Antibacterial Agent
      Mitsuo Murata, Ikumi Tamai, Yoshimichi Sai, Osamu Nagata, Hideo Kato, Yuichi Sugiyama and Akira Tsuji
      Drug Metabolism and Disposition November 1998, 26 (11) 1113-1119;
    2. You have access
      Dose-Dependent Effects of PSC 833 on Its Tissue Distribution and on the Biliary Excretion of Endogenous Substrates in Rats
      SaeHeum Song, Hiroshi Suzuki, Ryosei Kawai, Chiaki Tanaka, Izumi Akasaka and Yuichi Sugiyama
      Drug Metabolism and Disposition November 1998, 26 (11) 1128-1133;
  13. Suzuki, Hiroshi

    1. You have access
      Dose-Dependent Effects of PSC 833 on Its Tissue Distribution and on the Biliary Excretion of Endogenous Substrates in Rats
      SaeHeum Song, Hiroshi Suzuki, Ryosei Kawai, Chiaki Tanaka, Izumi Akasaka and Yuichi Sugiyama
      Drug Metabolism and Disposition November 1998, 26 (11) 1128-1133;

T

  1. Tamai, Ikumi

    1. You have access
      Hepatobiliary Transport Kinetics of HSR-903, a New Quinolone Antibacterial Agent
      Mitsuo Murata, Ikumi Tamai, Yoshimichi Sai, Osamu Nagata, Hideo Kato, Yuichi Sugiyama and Akira Tsuji
      Drug Metabolism and Disposition November 1998, 26 (11) 1113-1119;
  2. Tanaka, Chiaki

    1. You have access
      Dose-Dependent Effects of PSC 833 on Its Tissue Distribution and on the Biliary Excretion of Endogenous Substrates in Rats
      SaeHeum Song, Hiroshi Suzuki, Ryosei Kawai, Chiaki Tanaka, Izumi Akasaka and Yuichi Sugiyama
      Drug Metabolism and Disposition November 1998, 26 (11) 1128-1133;
  3. Thompson, Charles D.

    1. You have access
      Potentially Reactive Cyclic Carbamate Metabolite of the Antiepileptic Drug Felbamate Produced by Human Liver Tissue In Vitro
      Izet M. Kapetanovic, Cynthia D. Torchin, Charles D. Thompson, Thomas A. Miller, Patrick J. McNeilly, Timothy L. Macdonald, Harvey J. Kupferberg, James L. Perhach, R. Duane Sofia and John M. Strong
      Drug Metabolism and Disposition November 1998, 26 (11) 1089-1095;
  4. Tjernberg, Agneta

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      1- and 3-Hydroxylations, in Addition to 4-Hydroxylation, of Debrisoquine Are Catalyzed by Cytochrome P450 2D6 in Humans
      Birgit Eiermann, Per Olof Edlund, Agneta Tjernberg, Per Dalén, Marja-Liisa Dahl and Leif Bertilsson
      Drug Metabolism and Disposition November 1998, 26 (11) 1096-1101;
  5. Torchin, Cynthia D.

    1. You have access
      Potentially Reactive Cyclic Carbamate Metabolite of the Antiepileptic Drug Felbamate Produced by Human Liver Tissue In Vitro
      Izet M. Kapetanovic, Cynthia D. Torchin, Charles D. Thompson, Thomas A. Miller, Patrick J. McNeilly, Timothy L. Macdonald, Harvey J. Kupferberg, James L. Perhach, R. Duane Sofia and John M. Strong
      Drug Metabolism and Disposition November 1998, 26 (11) 1089-1095;
  6. Török, Michael

    1. You have access
      Transport of the β-Lactam Antibiotic Benzylpenicillin and the Dipeptide Glycylsarcosine by Brain Capillary Endothelial Cells In Vitro
      Michael Török, Jörg Huwyler, Jürgen Drewe, Heike Gutmann and Gert Fricker
      Drug Metabolism and Disposition November 1998, 26 (11) 1144-1148;
  7. Tsuji, Akira

    1. You have access
      Hepatobiliary Transport Kinetics of HSR-903, a New Quinolone Antibacterial Agent
      Mitsuo Murata, Ikumi Tamai, Yoshimichi Sai, Osamu Nagata, Hideo Kato, Yuichi Sugiyama and Akira Tsuji
      Drug Metabolism and Disposition November 1998, 26 (11) 1113-1119;

V

  1. VandenBranden, Mark

    1. You have access
      Alterations of the Catalytic Activities of Drug-Metabolizing Enzymes in Cultures of Human Liver Slices
      Mark VandenBranden, Steven A. Wrighton, Sean Ekins, Jennifer S. Gillespie, Shelly N. Binkley, Barbara J. Ring, Melinda G. Gadberry, D. Charlene Mullins, Stephen C. Strom and Charles B. Jensen
      Drug Metabolism and Disposition November 1998, 26 (11) 1063-1068;
  2. Verhoeven, C. H. J.

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      In Vitro and In Vivo Metabolism of the Progestagen Org 30659 in Several Species
      C. H. J. Verhoeven, S. F. M. Krebbers, G. N. Wagenaars, C. J. Booy, G. M. M. Groothuis, P. Olinga and R. M. E. Vos
      Drug Metabolism and Disposition November 1998, 26 (11) 1102-1112;
  3. Vos, R. M. E.

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      In Vitro and In Vivo Metabolism of the Progestagen Org 30659 in Several Species
      C. H. J. Verhoeven, S. F. M. Krebbers, G. N. Wagenaars, C. J. Booy, G. M. M. Groothuis, P. Olinga and R. M. E. Vos
      Drug Metabolism and Disposition November 1998, 26 (11) 1102-1112;

W

  1. Wagenaars, G. N.

    1. You have access
      In Vitro and In Vivo Metabolism of the Progestagen Org 30659 in Several Species
      C. H. J. Verhoeven, S. F. M. Krebbers, G. N. Wagenaars, C. J. Booy, G. M. M. Groothuis, P. Olinga and R. M. E. Vos
      Drug Metabolism and Disposition November 1998, 26 (11) 1102-1112;
  2. Wrighton, Steven A.

    1. You have access
      Alterations of the Catalytic Activities of Drug-Metabolizing Enzymes in Cultures of Human Liver Slices
      Mark VandenBranden, Steven A. Wrighton, Sean Ekins, Jennifer S. Gillespie, Shelly N. Binkley, Barbara J. Ring, Melinda G. Gadberry, D. Charlene Mullins, Stephen C. Strom and Charles B. Jensen
      Drug Metabolism and Disposition November 1998, 26 (11) 1063-1068;

Y

  1. Yamazaki, Hiroshi

    1. You have access
      Comparative Studies of In Vitro Inhibition of Cytochrome P450 3A4-Dependent Testosterone 6β-Hydroxylation by Roxithromycin and Its Metabolites, Troleandomycin, and Erythromycin
      Hiroshi Yamazaki and Tsutomu Shimada
      Drug Metabolism and Disposition November 1998, 26 (11) 1053-1057;
  2. Yan, Zimeng

    1. You have access
      Pharmacokinetics and Metabolism of [14C]Dichloroacetate in Male Sprague-Dawley Rats
      Margaret O. James, Zimeng Yan, Rachel Cornett, V. Murali K. M. Jayanti, George N. Henderson, Natalia Davydova, Michael J. Katovich, Brad Pollock and Peter W. Stacpoole
      Drug Metabolism and Disposition November 1998, 26 (11) 1134-1143;
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In this issue

Drug Metabolism and Disposition
Vol. 26, Issue 11
1 Nov 1998
  • Table of Contents
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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