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Research ArticleArticle

Pharmacokinetics and Metabolism of [14C]Dichloroacetate in Male Sprague-Dawley Rats

Identification of Glycine Conjugates, Including Hippurate, as Urinary Metabolites of Dichloroacetate

Margaret O. James, Zimeng Yan, Rachel Cornett, V. Murali K. M. Jayanti, George N. Henderson, Natalia Davydova, Michael J. Katovich, Brad Pollock and Peter W. Stacpoole
Drug Metabolism and Disposition November 1998, 26 (11) 1134-1143;

Article Information

vol. 26 no. 11 1134-1143
PubMed 
9806957
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received February 13, 1998
  • Accepted July 9, 1998
  • Published online November 1, 1998.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Margaret O. James,
  2. Zimeng Yan1,
  3. Rachel Cornett,
  4. V. Murali K. M. Jayanti2,
  5. George N. Henderson,
  6. Natalia Davydova,
  7. Michael J. Katovich,
  8. Brad Pollock and
  9. Peter W. Stacpoole
  1. Departments of Medicinal Chemistry (MOJ, RC, VMKMJ) and Pharmacodynamics (MJK), College of Pharmacy, and Department of Medicine, Division of Endocrinology and Metabolism (ZY, GNH, ND, PWS), Department of Health Policy and Epidemiology (BP), and Department of Biochemistry and Molecular Biology (PWS), College of Medicine, University of Florida
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    Research ArticleArticle

    Pharmacokinetics and Metabolism of [14C]Dichloroacetate in Male Sprague-Dawley Rats

    Margaret O. James, Zimeng Yan, Rachel Cornett, V. Murali K. M. Jayanti, George N. Henderson, Natalia Davydova, Michael J. Katovich, Brad Pollock and Peter W. Stacpoole
    Drug Metabolism and Disposition November 1, 1998, 26 (11) 1134-1143;
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