Table of Contents

Articles

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  Preface

  James R. Halpert and Guest Editor

  Drug Metabolism and Disposition December 1998, 26 (12) 1167;
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  The 1996 Bernard B. Brodie Lecture

  Anthony Y. H. Lu

  Drug Metabolism and Disposition December 1998, 26 (12) 1168-1173;
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  The Life and Times of Anthony Y. H. Lu

  Gerald T. Miwa

  Drug Metabolism and Disposition December 1998, 26 (12) 1174;
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  Twenty Years of Biochemistry of Human P450s

  F. Peter Guengerich, Natilie A. Hosea, Asit Parikh, L. Chastine Bell-Parikh, William W. Johnson, Elizabeth M. J. Gillam and Tsutomu Shimada

  Drug Metabolism and Disposition December 1998, 26 (12) 1175-1178;
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  Molecular Basis of P450 Inhibition and Activation

  Grazyna D. Szklarz and James R. Halpert

  Drug Metabolism and Disposition December 1998, 26 (12) 1179-1184;
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  Nitric Oxide Synthase Structure and Electron Transfer

  Paul R. Ortiz de Montellano, Clinton Nishida, Ignacio Rodriguez-Crespo and Nancy Gerber

  Drug Metabolism and Disposition December 1998, 26 (12) 1185-1189;
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  Multiple Activated Oxygen Species in P450 Catalysis

  Minor J. Coon, Alfin D. N. Vaz, Dermot F. McGinnity and Hwei-Ming Peng

  Drug Metabolism and Disposition December 1998, 26 (12) 1190-1193;
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  The Aryl Hydrocarbon Receptor

  Frank J. Gonzalez and Pedro Fernandez-Salguero

  Drug Metabolism and Disposition December 1998, 26 (12) 1194-1198;
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  Lanosterol 14α-Demethylase (CYP51) and Spermatogenesis

  Damjana Rozman and Michael R. Waterman

  Drug Metabolism and Disposition December 1998, 26 (12) 1199-1201;
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  Applications and Limitations of Interspecies Scaling and In Vitro Extrapolation in Pharmacokinetics

  Jiunn H. Lin

  Drug Metabolism and Disposition December 1998, 26 (12) 1202-1212;
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  Short- and Long-Term Projections About the Use of Drug Metabolism in Drug Discovery and Development

  Ronald E. White

  Drug Metabolism and Disposition December 1998, 26 (12) 1213-1216;
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  Drug-Metabolism Research Challenges in the New Millennium

  Anthony Y. H. Lu

  Drug Metabolism and Disposition December 1998, 26 (12) 1217-1222;
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  Structure-Function of Cytochromes P450 and Flavin-Containing Monooxygenases

  James R. Halpert, Tammy L. Domanski, Orhan Adali, Christine P. Biagini, Jose Cosme, Elizabeth A. Dierks, Eric F. Johnson, Jeffrey P. Jones, Paul Ortiz de Montellano, Richard M. Philpot, Ole Sibbesen, W. Keith Wyatt and Zhoupeng Zheng

  Drug Metabolism and Disposition December 1998, 26 (12) 1223-1231;
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  Physiological and Pathophysiological Regulation of Cytochrome P450

  Edward T. Morgan, Marion B. Sewer, Heinrich Iber, Frank J. Gonzalez, Ying-Hue Lee, Robert H. Tukey, Steve Okino, Tien Vu, Yue-Hwa Chen, Jaspreet S. Sidhu and Curtis J. Omiecinski

  Drug Metabolism and Disposition December 1998, 26 (12) 1232-1240;