Applications and Limitations of Interspecies Scaling and In Vitro Extrapolation in Pharmacokinetics

Jiunn H. Lin

Article Information

vol. 26 no. 12 1202-1212

PubMed

9860929

Published By

American Society for Pharmacology and Experimental Therapeutics

Print ISSN

0090-9556

Online ISSN

1521-009X

History

Published online December 1, 1998.

The American Society for Pharmacology and Experimental Therapeutics

Author Information

Jiunn H. Lin

Department of Drug Metabolism, Merck Research Laboratories

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	Abstract	Full	Pdf
Jan 1999	19	124	63
Feb 1999	18	67	34
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Apr 1999	7	30	6
May 1999	2	16	13
Jun 1999	1	18	11
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Dec 2010	9	25	14
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Jul 2011	22	13	19
Aug 2011	20	13	16
Sep 2011	37	55	29
Oct 2011	15	32	11
Nov 2011	23	53	27
Dec 2011	23	48	43
Jan 2012	29	36	25
Feb 2012	27	44	33
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Oct 2012	21	68	50
Nov 2012	20	81	33
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Jan 2013	40	53	51
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Jul 2013	17	21	15
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Oct 2013	18	15	12
Nov 2013	18	18	23
Dec 2013	20	32	16
Jan 2014	22	20	26
Feb 2014	11	51	18
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Apr 2014	21	40	11
May 2014	15	60	24
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Jul 2014	10	33	13
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Oct 2014	15	21	13
Nov 2014	16	30	9
Dec 2014	20	17	12
Jan 2015	12	26	9
Feb 2015	9	25	18
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Apr 2015	17	21	5
May 2015	15	20	8
Jun 2015	8	27	6
Jul 2015	18	44	19
Aug 2015	24	26	73
Sep 2015	119	32	15
Oct 2015	9	20	8
Nov 2015	16	30	16
Dec 2015	9	15	9
Jan 2016	10	15	11
Feb 2016	42	14	6
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Apr 2016	15	34	8
May 2016	5	17	4
Jun 2016	13	25	15
Jul 2016	9	18	7
Aug 2016	4	16	3
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Oct 2016	15	45	17
Nov 2016	8	53	28
Dec 2016	3	35	18
Jan 2017	8	39	12
Feb 2017	6	61	17
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Apr 2017	5	20	7
May 2017	11	26	20
Jun 2017	7	18	5
Jul 2017	6	30	20
Aug 2017	23	37	7
Sep 2017	4	35	13
Oct 2017	8	37	67
Nov 2017	9	61	21
Dec 2017	9	25	14
Jan 2018	4	26	9
Feb 2018	1	16	4
Mar 2018	1	62	9
Apr 2018	1	32	2
May 2018	0	44	11
Jun 2018	0	27	9
Jul 2018	4	21	15
Aug 2018	2	20	9
Sep 2018	0	26	9
Oct 2018	2	24	13
Nov 2018	8	33	15
Dec 2018	32	19	5
Jan 2019	69	2	1
Feb 2019	24	4	5
Mar 2019	24	4	3
Apr 2019	36	3	4
May 2019	29	3	6
Jun 2019	20	1	5
Jul 2019	27	2	2
Aug 2019	26	2	2
Sep 2019	37	3	5
Oct 2019	30	3	2
Nov 2019	38	1	0
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Jan 2020	18	0	0
Feb 2020	15	2	1
Mar 2020	18	7	2
Apr 2020	28	3	2
May 2020	16	0	1
Jun 2020	17	1	1
Jul 2020	36	5	6
Aug 2020	15	3	3
Sep 2020	20	2	0
Oct 2020	13	1	1
Nov 2020	48	4	3
Dec 2020	32	3	4
Jan 2021	56	11	4
Feb 2021	15	15	1
Mar 2021	5	2	2